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2610//16 1 Allele-specific expression, ASE [1] Defini8on of allele
... • feat: FeatureID as specified in the input file (typically a gene idenBfier) • n.vars: Number of variants within the gene • mean.s: Mean of s across the variants within the gene • median.s: Median of s across the variants within the gene • sd.s: Standard deviaBon of s across the variants with ...
... • feat: FeatureID as specified in the input file (typically a gene idenBfier) • n.vars: Number of variants within the gene • mean.s: Mean of s across the variants within the gene • median.s: Median of s across the variants within the gene • sd.s: Standard deviaBon of s across the variants with ...
Genome Science performed with e-Science Tools
... to identify overlapping sequences. Only new or improved hits are relevant, and so the results are first translated into a simplified format using “SIMPLIFIER”, before being compared to the results of the previous run using the “COMPARER” service. “RETRIEVE” takes new hits and determines which are lo ...
... to identify overlapping sequences. Only new or improved hits are relevant, and so the results are first translated into a simplified format using “SIMPLIFIER”, before being compared to the results of the previous run using the “COMPARER” service. “RETRIEVE” takes new hits and determines which are lo ...
Genetic identification of eleven aquatic bacteria using the 16S rDNA
... Sequences were compared to other sequences from the genetic nucleotide library by using BLAST. The 16S rDNA gene sequences size was modified for each sample by eliminating undefined nucleotides at the beginning and at the end of the sequences because the peaks on that section are not well defined (T ...
... Sequences were compared to other sequences from the genetic nucleotide library by using BLAST. The 16S rDNA gene sequences size was modified for each sample by eliminating undefined nucleotides at the beginning and at the end of the sequences because the peaks on that section are not well defined (T ...
Discovery of MLL1 binding units, their localization to CpG Islands
... Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothing is known about sequence features that may act as TREs in mammalian genomic DNA. Results: By analyzing results ...
... Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothing is known about sequence features that may act as TREs in mammalian genomic DNA. Results: By analyzing results ...
Acta Biotheoretica 47: 29-40, 1999 ON THE ADAPTIVE VALUE OF
... alleles relative to other alleles, making it a strategy with high evolutionary stability in terms of the genetic dynamics, but with little effect on the average fitness of populations. Otherwise, assortative mating based on more general criteria (MSC 8 and MSC 11, Fig. 1), had a comparable fitness t ...
... alleles relative to other alleles, making it a strategy with high evolutionary stability in terms of the genetic dynamics, but with little effect on the average fitness of populations. Otherwise, assortative mating based on more general criteria (MSC 8 and MSC 11, Fig. 1), had a comparable fitness t ...
Nature Genetics: doi:10.1038/ng.3791
... locations from the analysis3-5. To address this potential bias, we created a genome-wide mappability map of each DGRP line for each position in the genome and used this to pre-filter regions that are likely to introduce artificial associations: Raw sequencing reads from the DGRP genome-sequencing pr ...
... locations from the analysis3-5. To address this potential bias, we created a genome-wide mappability map of each DGRP line for each position in the genome and used this to pre-filter regions that are likely to introduce artificial associations: Raw sequencing reads from the DGRP genome-sequencing pr ...
A novel duplication in the HOXA13 gene in a family with atypical
... There are several reasons to question whether the malformations seen in patients heterozygous for the different mutations in HOXA13 are the result of haploinsufficiency. The patient with a heterozygous deletion of the entire HOXA cluster has a relatively mild HFGS phenotype, in particular with regar ...
... There are several reasons to question whether the malformations seen in patients heterozygous for the different mutations in HOXA13 are the result of haploinsufficiency. The patient with a heterozygous deletion of the entire HOXA cluster has a relatively mild HFGS phenotype, in particular with regar ...
GroEL buffers against deleterious mutations
... density during growth overnight. A simple explanation could be that an overproduction of GroEL of about 8616-fold is deleterious because it diverts amino acids away from other cellular functions. To test this, we grew each groE c strain and its ancestor in DM25 supplemented with increasing concentr ...
... density during growth overnight. A simple explanation could be that an overproduction of GroEL of about 8616-fold is deleterious because it diverts amino acids away from other cellular functions. To test this, we grew each groE c strain and its ancestor in DM25 supplemented with increasing concentr ...
Statistical power and significance testing in large
... ethnic origin) or principal components that are derived from a subset of the SNPs scattered throughout the genome12,13. As many SNPs are being tested, keeping the significance threshold at the conventional value of 0.05 would lead to a large number of false-positive significant results. For example, ...
... ethnic origin) or principal components that are derived from a subset of the SNPs scattered throughout the genome12,13. As many SNPs are being tested, keeping the significance threshold at the conventional value of 0.05 would lead to a large number of false-positive significant results. For example, ...
What is an Evolutionary Algorithm?
... • All proteins in life on earth are composed of sequences built from 20 different amino acids • DNA is built from four nucleotides in a double helix spiral: purines A,G; pyrimidines T,C • Triplets of these from codons, each of which codes for a specific amino acid • Much redundancy: ...
... • All proteins in life on earth are composed of sequences built from 20 different amino acids • DNA is built from four nucleotides in a double helix spiral: purines A,G; pyrimidines T,C • Triplets of these from codons, each of which codes for a specific amino acid • Much redundancy: ...
Genes - Teachnet UK-home
... Question 10 In the 1990’s scientist calculated the sequence of bases in human chromosomes was around 3 billion bases long. What did the scientist call this experiment? • The human gene experiment • Gene count 1999 ...
... Question 10 In the 1990’s scientist calculated the sequence of bases in human chromosomes was around 3 billion bases long. What did the scientist call this experiment? • The human gene experiment • Gene count 1999 ...
Egg production
... than in commercial egg-laying strains where persistency is good. For this reason selection for rapid growth rate and feed conversion efficiency in broilers is associated with poor reproductive efficiency in broiler breeders. The aim of the research is to identify genetic markers for marker assisted ...
... than in commercial egg-laying strains where persistency is good. For this reason selection for rapid growth rate and feed conversion efficiency in broilers is associated with poor reproductive efficiency in broiler breeders. The aim of the research is to identify genetic markers for marker assisted ...
Color and Scent: How Single Genes Influence Pollinator Attraction
... color variants and the genes that determine these. So far, the molecular basis of natural variation is known for only two pollination syndrome traits: petal color, specifically anthocyanin-based color, and scent production. We discuss the types of genes that have been found, their role in the attrac ...
... color variants and the genes that determine these. So far, the molecular basis of natural variation is known for only two pollination syndrome traits: petal color, specifically anthocyanin-based color, and scent production. We discuss the types of genes that have been found, their role in the attrac ...
Male-Biased Mutation Rate and Divergence in Autosomal, Z
... Orthologous chicken and turkey introns were aligned by use of ClustalW on default settings (Thompson, Higgins, and Gibson 1994), although some manual adjustment was required to improve the alignment of repetitive sequences. Pairwise distances were estimated by use of the baseml program in PAML versi ...
... Orthologous chicken and turkey introns were aligned by use of ClustalW on default settings (Thompson, Higgins, and Gibson 1994), although some manual adjustment was required to improve the alignment of repetitive sequences. Pairwise distances were estimated by use of the baseml program in PAML versi ...
LIVESTOCK PRODUCTION - Spencer
... Echtyma: sore mouth—contagious to sheep & humans, vaccines can be used Enterotoxemia: all ages susceptible, avoid feeding excess milk or grain Goat pox: lesions on mucous membranes and skin, not prevalent in U.S. Tetanus: infects wounds and causes death, annual boosters control the disease ...
... Echtyma: sore mouth—contagious to sheep & humans, vaccines can be used Enterotoxemia: all ages susceptible, avoid feeding excess milk or grain Goat pox: lesions on mucous membranes and skin, not prevalent in U.S. Tetanus: infects wounds and causes death, annual boosters control the disease ...
THE EVOLUTION OF SELECTIVE ADVANTAGE IN A
... heterozygote has an optiiiium fitness above the wild type’s. If, however, the mutation only changes the value of the wild type, its fitness can only be raised to the wild type’s fitness, and dominance but not overdominance will evolve. The mutation must therefore cause a qualitative change in the ch ...
... heterozygote has an optiiiium fitness above the wild type’s. If, however, the mutation only changes the value of the wild type, its fitness can only be raised to the wild type’s fitness, and dominance but not overdominance will evolve. The mutation must therefore cause a qualitative change in the ch ...
The riboswitch control of bacterial metabolism
... enzymes for riboflavin synthesis from GTP [9]. The operon has an untranslated regulatory leader region of , 300 base pairs in front of its first gene. The leader is responsible for negative regulation of the operon by flavins. Intensive genetic and genomic studies of the rib leader in B. subtilis an ...
... enzymes for riboflavin synthesis from GTP [9]. The operon has an untranslated regulatory leader region of , 300 base pairs in front of its first gene. The leader is responsible for negative regulation of the operon by flavins. Intensive genetic and genomic studies of the rib leader in B. subtilis an ...
PDF - Atlas of Genetics and Cytogenetics in Oncology and
... • A possesses alleles a1 and a2. It transmits to the great-grandparents GGP: • either identical alleles (a1 and a1 or: a2 and a2) --> proba: 1/2 • or different alleles (a1 and a2 or: a2 et a1), but... if A itself exhibits consanguinity (with a coefficient of consanguinity FA), then a1 and a2 have a ...
... • A possesses alleles a1 and a2. It transmits to the great-grandparents GGP: • either identical alleles (a1 and a1 or: a2 and a2) --> proba: 1/2 • or different alleles (a1 and a2 or: a2 et a1), but... if A itself exhibits consanguinity (with a coefficient of consanguinity FA), then a1 and a2 have a ...
Chpt9_Transposition.doc
... propagating themselves. We now realize that some transposable elements are also viruses, for instance, some retroviruses can integrate into a host genome to form endogenous retroviruses. Indeed, some viruses may be derived from natural transposable elements and vice versa. Since viruses move between ...
... propagating themselves. We now realize that some transposable elements are also viruses, for instance, some retroviruses can integrate into a host genome to form endogenous retroviruses. Indeed, some viruses may be derived from natural transposable elements and vice versa. Since viruses move between ...
Insights into three whole-genome duplications gleaned
... biaurelia, 10,970 P. tetraurelia, and 10,024 P. sexaurelia genes (Files S1-S2). This represents about 30% of the genes in each of the aligned genomes, as missing data in any of one of the twelve scaffolds being aligned caused a region to be excluded. We also identified 305 ancestral genes that exist ...
... biaurelia, 10,970 P. tetraurelia, and 10,024 P. sexaurelia genes (Files S1-S2). This represents about 30% of the genes in each of the aligned genomes, as missing data in any of one of the twelve scaffolds being aligned caused a region to be excluded. We also identified 305 ancestral genes that exist ...
Pedigree analysis through genetics hypothesis testing
... Genetic testing shows that individual 4 has only nonmutant alleles of both genes. Genetic testing also shows that individual 12 has pnly mutant alleles of both genes. There are four basic hypotheses to test: X-linked dominant and recessive, and autosomal dominant and recessive. ...
... Genetic testing shows that individual 4 has only nonmutant alleles of both genes. Genetic testing also shows that individual 12 has pnly mutant alleles of both genes. There are four basic hypotheses to test: X-linked dominant and recessive, and autosomal dominant and recessive. ...