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Genome Projector: zoomable genome map with multiple views
Genome Projector: zoomable genome map with multiple views

... which can be toggled with buttons located in the upperright corner (Figure 3B). In Genome Projector, the overlay for the Genome Map shows the predicted gene expression levels calculated using the Codon Adaptation Index (CAI) [37]. CAI measures the relative adaptiveness of the synonymous codon usage ...
11.1 app notes
11.1 app notes

... -don’t always know there are carriers of disorder -parents may not know the disorder is in the family ------------------------------------------------------------------------------parents with a dominant disorder may choose to not have children or may not survive to age of procreation ...
Genomics
Genomics

... MAKE NO REPRESENTATIONS OR WARRANTIES, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. University will not be liable for any costs, damages, fees or other liability, nor for any direct, indirect, special, incidental or ...
PDF - 2.6 MB
PDF - 2.6 MB

... Your classmate discovers an X-linked male-sterile mutant that arose spontaneously in her mouse colony. Having heard about your studies of the human SPG gene, she points out that most genes on the human X chromosome have counterparts on the mouse X chromosome, and that her male-sterile mice might be ...
The photosynthetic apparatus of Prochlorococcus
The photosynthetic apparatus of Prochlorococcus

... supported clade, which can be further divided into two clusters (Urbach et al., 1998; Rocap et al., 1999; Fig. 2). In contrast, the high B/A isolates, while distinctly different from the low B/A isolates, do not form a monophyletic clade of their own but instead are divided among four clusters (Roca ...
Quantitative trait loci and the study of plant domestication
Quantitative trait loci and the study of plant domestication

... has also played a more subtle historical role as the foundation of the modern study of evolution and adaptation. Until recently, however, researchers interested in domestication were limited to studying phenotypic changes or the genetics of simple Mendelian traits, when often the characters of most ...
Evolutionary implications of non- neutral
Evolutionary implications of non- neutral

... proceed via a model in which adaptive mutations in one genome select for a response in the other (Box 2). This likelihood might well be increased if environmental (e.g. thermal) selection is driving this co-evolution, as discussed later. mtDNA effects on fitness Here, we showcase the most recent lit ...
Lyons/Hewitt/Suchocki/Yeh, CONCEPTUAL INTEGRATED SCIENCE
Lyons/Hewitt/Suchocki/Yeh, CONCEPTUAL INTEGRATED SCIENCE

... By 1950, scientists knew DNA was the genetic material, but they did not know the structure of DNA. In 1953, Watson and Crick built a model of DNA that was consistent with available evidence. They used X-ray photos of DNA taken by Franklin and Wilkins as part of their research. ...
Stochasticity and variability in the dynamics and genetics of
Stochasticity and variability in the dynamics and genetics of

... s genetic variability maintained by selection-mutation balance, or by neutral mutations? Perhaps by pleiotropy? How does drift affects variability? These are typical questions that population genetics (PG) and quantitative genetics (QG) ask. These disciplines describe the evolution at the levels of ...
Slide 1
Slide 1

... 1) IL-17A, IL-17F and IL-23R are important regulators of immune response and may be associated with bone ...
Resistance genes in barley - Journal of Applied Genetics
Resistance genes in barley - Journal of Applied Genetics

... The number of putative resistance genes increased during the last five years. DNA markers developed to identify barley resistance genes are listed in Table 2. In early studies, most resistance genes were identified by using RFLP makers. Of the 28 markers developed, 22 are PCR-based. STS markers have ...
A single nucleotide polymorphism of the TNRC9 gene associated
A single nucleotide polymorphism of the TNRC9 gene associated

... reported that close relatives of patients have an approximately 2-fold increased risk of cancer, and the genetic factors believed to be most crucial have been revealed from twin studies (Peto and Mack, 2000; Pharoah et al., 2004). TNRC9 (trinucleotide-repeat-containing 9), also termed TOX3, was firs ...
Association of (rs1801133) Polymorphism with Breast
Association of (rs1801133) Polymorphism with Breast

... DNA sequence variation which is common in the main population. So in this case no single allele is taken as the standard sequence. Instead there are two or more equally acceptable alternatives. SNPs are biological markers which can help in determining the location of the genes associated with diseas ...
Article Genetic Signatures Reveal High-Altitude
Article Genetic Signatures Reveal High-Altitude

... small divergence time. Therefore, we expect the signal of positive selection to remain detectable in the populations considered here, even if their current environment does not expose them to such extreme selection pressure. Both the Amhara and Tigray populations share the same Semitic language grou ...
Causes, consequences and solutions of
Causes, consequences and solutions of

... throughout biology such as in studies of human diseases: for epidemiological investigations [1–3], for identifying and characterizing newly discovered pathogens [4, 5] and for identifying and tracking natural reservoirs of zoonotic diseases [6]. In addition, phylogenetic analysis has been widely use ...
It`s in the Genes - CR Alpacas, Inc.
It`s in the Genes - CR Alpacas, Inc.

... development. Melanin is also a critical structural component of cells, including hairs in the cochlea in the inner ear. Failure of melanin to reach these cochlear hairs results in their death soon after birth, and deafness. Similarly, failure of pigment cells to reach the cells that will become the ...
Information Encoding in Biological Molecules: DNA and
Information Encoding in Biological Molecules: DNA and

... info, gene structure ...
View - OhioLINK Electronic Theses and Dissertations Center
View - OhioLINK Electronic Theses and Dissertations Center

... Centrosomes are highly conserved organelles that are composed of two microtubule-based centrioles surrounded by an amorphous protein cloud of pericentriolar material (PCM), which is able to nucleate astral microtubules. They serve as microtubule organizing centers during cell division and are import ...
Drawings of Chromosome Movement During Meiosis
Drawings of Chromosome Movement During Meiosis

... encouraged to review this concept at this time. Be sure that each of the items on the list below is incorporated in your drawings. The instructions request that you draw the chromosomes during each phase and that you draw the spindle fibers for metaphase and anaphase. Refer to your textbook and note ...
ppt
ppt

... 1) No mate need 2) All genes transferred to every offspring 3) Offspring survival high in same environment Costs 1) “Muller’s ratchet” 2) Mutation (rare) only source of variation 3) Offspring survival is “all or none” in a changing environment ...
More than Meets the Eye: The Genetics of Eye Color
More than Meets the Eye: The Genetics of Eye Color

... Their curiosity further piqued, Alexia and Evan contacted Dr. Rick Sturm1 at the University of Queensland, a leading expert on eye color. “It used to be thought that eye colour was what we call a simple Mendelian recessive trait—in other words, brown eye colour was dominant over blue, so a person wi ...
Journal of Genomics The Sex Chromosomes of Frogs: Variability
Journal of Genomics The Sex Chromosomes of Frogs: Variability

... should have greater ability to tolerate sex chromosome evolution. These recent studies have revealed many exciting new ideas for how sex chromosome homomorphy might be maintained. Indeed, homomorphy is the most abundant state of sex chromosome morphology in all animals, yet most theory has focused o ...
Evolutionary relationships and diversification of barhl genes within
Evolutionary relationships and diversification of barhl genes within

... the retina as early as 35 hpf (Figure 1B). At this stage, most RGCs and the first ACs are born [15]. Barhl2 transcripts are initially localized in a few cells in the central retina and subsequently expressed in the whole retina (Figure 1A-C), in a pattern matching the wave of AC genesis. At 40 hpf, ...
The Optimal Discovery Procedure II: Applications to Comparative
The Optimal Discovery Procedure II: Applications to Comparative

... through the application of large-scale significance testing. For example, significance analyses are often performed in DNA microarray, comparative genomic hybridization, genome-wide comparative genomics, protein array, mass spectrometry, and genome-wide association studies (3–5). We propose a new ap ...
Symbiosis, Evolvability and Modularity
Symbiosis, Evolvability and Modularity

... with anti-outlaw criteria. The problem of defection was first noted in the context of group selective explanations of altruism (Sober and Wilson 1998), and it has subsequently been applied to the evolution of multi-celled organisms (Buss 1987; Maynard Smith and Szathmary 1995; Michod 1999). To the e ...
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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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