Molecular mechanisms of the origin of micronuclei
... chromosome-type micronuclei, because they arise independently in a single cell, and an intermediate mixed type was rarely detected (15). Furthermore, purified DM-type micronuclei contained essentially pure DM’s DNA (16). The reason for the appearance of such DM-type micronuclei was obtained from the ...
... chromosome-type micronuclei, because they arise independently in a single cell, and an intermediate mixed type was rarely detected (15). Furthermore, purified DM-type micronuclei contained essentially pure DM’s DNA (16). The reason for the appearance of such DM-type micronuclei was obtained from the ...
Lesson Plan, GeneChip® Microarrays: Teacher`s Guide
... decide to cut out some of the questions to lessen the workload. Or, you could have the students write their own questions for the material and then bring them to class the next day to switch with other students. Then, in class they could answer each others questions as the warm up for the day. Depen ...
... decide to cut out some of the questions to lessen the workload. Or, you could have the students write their own questions for the material and then bring them to class the next day to switch with other students. Then, in class they could answer each others questions as the warm up for the day. Depen ...
Single Nucleotide Polymorphism (SNP) 分析與應用
... • SNPs are useful for finding genes that contribute to disease, in two ways. Some SNP alleles are the actual DNA sequence variants that cause differences in gene function or regulation that directly contribute to disease processes. Most SNP alleles, however, probably contribute little to disease. Th ...
... • SNPs are useful for finding genes that contribute to disease, in two ways. Some SNP alleles are the actual DNA sequence variants that cause differences in gene function or regulation that directly contribute to disease processes. Most SNP alleles, however, probably contribute little to disease. Th ...
Japanese morning glory dusky mutants displaying reddish
... blue flowers (Figure 1b) that contain the peonidin (3¢-methylcyanidin) 3-O-sophoroside derivative named Heavenly Blue Anthocyanin (HBA) (Figure 1f; Kondo et al., 1987; Lu et al., 1992), and a number of spontaneous mutants exhibiting various flower colors have been isolated since the 17th century (Ii ...
... blue flowers (Figure 1b) that contain the peonidin (3¢-methylcyanidin) 3-O-sophoroside derivative named Heavenly Blue Anthocyanin (HBA) (Figure 1f; Kondo et al., 1987; Lu et al., 1992), and a number of spontaneous mutants exhibiting various flower colors have been isolated since the 17th century (Ii ...
Genome-wide histone modification patterns in
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
... bioRxiv preprint first posted online Feb. 15, 2016; doi: http://dx.doi.org/10.1101/039776. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
Punnet squares lecture
... largely as a result of independent work in the early 20th century by Godfrey Hardy, an English mathematician, and Wilhelm Weinberg, a German physician. Through mathematical modeling based on probability, they concluded in 1908 that gene pool frequencies are inherently stable but that evolution shoul ...
... largely as a result of independent work in the early 20th century by Godfrey Hardy, an English mathematician, and Wilhelm Weinberg, a German physician. Through mathematical modeling based on probability, they concluded in 1908 that gene pool frequencies are inherently stable but that evolution shoul ...
Genetics 1 - National Open University of Nigeria
... observations. Kolreuter and many others after him did not record the ratios in which the original parental characters occurred among the progeny. As we shall see later, it is therefore not surprising that the early hybridizers did not discover any underlying principles of inheritance. Thus, even tho ...
... observations. Kolreuter and many others after him did not record the ratios in which the original parental characters occurred among the progeny. As we shall see later, it is therefore not surprising that the early hybridizers did not discover any underlying principles of inheritance. Thus, even tho ...
Genetic Location of Heritable Traits Through Association Studies: A
... apply Luria-Delbrück equations, originally developed for bacterial mutation studies, and adapted in this work to obtain recombinational distances from LD measures. Finally, we will take a look at other alternative approaches that have been proposed. One of the most known and applied (see, for instan ...
... apply Luria-Delbrück equations, originally developed for bacterial mutation studies, and adapted in this work to obtain recombinational distances from LD measures. Finally, we will take a look at other alternative approaches that have been proposed. One of the most known and applied (see, for instan ...
Overview: Alcohol and Nicotine Use and Dependence: Common
... Among regular smokers, there may be a unidirectional or reciprocal causal relationship between nicotine and alcohol dependence - in discordant MZ pairs, who are genetically identical, the nicotine dependent twin is significantly more likely to also be alcohol dependent. ...
... Among regular smokers, there may be a unidirectional or reciprocal causal relationship between nicotine and alcohol dependence - in discordant MZ pairs, who are genetically identical, the nicotine dependent twin is significantly more likely to also be alcohol dependent. ...
Means (*) and standard deviation (s) of quantitative
... Among regular smokers, there may be a unidirectional or reciprocal causal relationship between nicotine and alcohol dependence - in discordant MZ pairs, who are genetically identical, the nicotine dependent twin is significantly more likely to also be alcohol dependent. ...
... Among regular smokers, there may be a unidirectional or reciprocal causal relationship between nicotine and alcohol dependence - in discordant MZ pairs, who are genetically identical, the nicotine dependent twin is significantly more likely to also be alcohol dependent. ...
characterizing the genetic bases of autosomal recessive disorders
... Autosomal recessive disorders have devastating effects on patients and their families. Elucidating the genetic bases of such disorders is essential to improve their clinical outcome and for implementing effective prevention programs. In this dissertation, the genetic bases of seven autosomal recessi ...
... Autosomal recessive disorders have devastating effects on patients and their families. Elucidating the genetic bases of such disorders is essential to improve their clinical outcome and for implementing effective prevention programs. In this dissertation, the genetic bases of seven autosomal recessi ...
Section 2
... for a single trait exist, some alleles may be dominant and others may be recessive. 3. Principle of Segregation- In most sexually reproducing organisms, each adult has two alleles of each gene—one from each parent. These alleles segregate from each other randomly and independently when gametes are f ...
... for a single trait exist, some alleles may be dominant and others may be recessive. 3. Principle of Segregation- In most sexually reproducing organisms, each adult has two alleles of each gene—one from each parent. These alleles segregate from each other randomly and independently when gametes are f ...
Ribosomopathies: human disorders of ribosome
... SDS was first reported in 1964 by Schwachman et al in a group of 5 children being followed in a cystic fibrosis clinic at Harvard University.40 SDS is an autosomal recessive disease, with an incidence estimated at 1 in 50 000 births, characterized by exocrine pancreatic insufficiency, ineffective he ...
... SDS was first reported in 1964 by Schwachman et al in a group of 5 children being followed in a cystic fibrosis clinic at Harvard University.40 SDS is an autosomal recessive disease, with an incidence estimated at 1 in 50 000 births, characterized by exocrine pancreatic insufficiency, ineffective he ...
chapt21_HumanBiology14e_lecture
... • Cystic fibrosis – Cl- ions do not pass normally through a cell membrane, resulting in thick mucus in lungs ...
... • Cystic fibrosis – Cl- ions do not pass normally through a cell membrane, resulting in thick mucus in lungs ...
Ribosomopathies: human disorders of ribosome
... SDS was first reported in 1964 by Schwachman et al in a group of 5 children being followed in a cystic fibrosis clinic at Harvard University.40 SDS is an autosomal recessive disease, with an incidence estimated at 1 in 50 000 births, characterized by exocrine pancreatic insufficiency, ineffective he ...
... SDS was first reported in 1964 by Schwachman et al in a group of 5 children being followed in a cystic fibrosis clinic at Harvard University.40 SDS is an autosomal recessive disease, with an incidence estimated at 1 in 50 000 births, characterized by exocrine pancreatic insufficiency, ineffective he ...
Ray-tracing Method for Estimating Radio Propagation Using Genetic
... generated, while also searching for ...
... generated, while also searching for ...
Chapter 10
... plants with each other, their offspring are the F2 generation—the second filial generation. You might find it easier to understand these terms if you ...
... plants with each other, their offspring are the F2 generation—the second filial generation. You might find it easier to understand these terms if you ...
exploring genetics - Cold Spring Harbor Laboratory
... from its original site to other parts of the body and can also be fatal if not treated adequately. CENTRAL DOGMA theory developed by Francis Crick that describes the sequential transfer of genetic information from DNA (genes) ’ RNA ’ protein in eukaryotic organisms. Some organisms such as retrovirus ...
... from its original site to other parts of the body and can also be fatal if not treated adequately. CENTRAL DOGMA theory developed by Francis Crick that describes the sequential transfer of genetic information from DNA (genes) ’ RNA ’ protein in eukaryotic organisms. Some organisms such as retrovirus ...
Neurofibromatosis, Type 1 - St. Jude Children`s Research Hospital
... Neurofibromatosis, type 1, is caused by changes in a gene known as NF1. Genes carry information telling cells within the body how to function. The NF1 gene helps to control how and when cells grow, divide and die. Most people without neurofibromatosis, type 1, carry two working copies of the NF1 gen ...
... Neurofibromatosis, type 1, is caused by changes in a gene known as NF1. Genes carry information telling cells within the body how to function. The NF1 gene helps to control how and when cells grow, divide and die. Most people without neurofibromatosis, type 1, carry two working copies of the NF1 gen ...
Bridging the gap between developmental systems theory and
... ``If development is to reenter evolutionary theory, it should be development that integrates genes into organisms, and organisms into the many levels of the environment that enter into their ontogenetic construction'' (p. 113).(5) In this task of deep contextualization, a central construct of DST is ...
... ``If development is to reenter evolutionary theory, it should be development that integrates genes into organisms, and organisms into the many levels of the environment that enter into their ontogenetic construction'' (p. 113).(5) In this task of deep contextualization, a central construct of DST is ...
Gene Section JAG1 (jagged 1 (Alagille syndrome)) Atlas of Genetics and Cytogenetics
... Table 2. EGF-like repeats of the human JAG1 protein. A : the 16 EGF motifs are aligned. A 24-amino acid insertion is present in EGF10 (in grey, as in human JAG2 protein). The numbers above the sequences refer to cysteine residues (C in blue). Each EGF-like repeat contains 6 cysteine residues, able t ...
... Table 2. EGF-like repeats of the human JAG1 protein. A : the 16 EGF motifs are aligned. A 24-amino acid insertion is present in EGF10 (in grey, as in human JAG2 protein). The numbers above the sequences refer to cysteine residues (C in blue). Each EGF-like repeat contains 6 cysteine residues, able t ...
Unbalanced translocation, a major chromosome alteration
... chromosomal segregation at mitosis and also through genetic alterations that change chromosomal structures of the cell (Lasko et al., 1991; Weinberg, 2007). In fact, whole, terminal and interstitial chromosome deletions were shown to cause LOH on several chromosomal loci in human cancers (Naylor et ...
... chromosomal segregation at mitosis and also through genetic alterations that change chromosomal structures of the cell (Lasko et al., 1991; Weinberg, 2007). In fact, whole, terminal and interstitial chromosome deletions were shown to cause LOH on several chromosomal loci in human cancers (Naylor et ...
Functional Divergence of the Nuclear Receptor NR2C1
... divergence within NRs. Combining these models can uncover functionally relevant patterns of evolution that may not be apparent when they are used in isolation (Schott et al. 2014). Prior to interpreting the modeling results, we carried out a suite of reliability and robustness analyses, which led us ...
... divergence within NRs. Combining these models can uncover functionally relevant patterns of evolution that may not be apparent when they are used in isolation (Schott et al. 2014). Prior to interpreting the modeling results, we carried out a suite of reliability and robustness analyses, which led us ...
Modulation of CTCF Insulator Function by
... LPS induction. In addition, short-term treatment with the inhibitor of transcriptional elongation, 5,6-dichloro-1-b-D-ribofuranosyl-benzimidazole, permitted transcription of many immediate-early genes but abrogated LPS-induced LINoCR expression, IKKa recruitment, histone H3 phosphoacetylation, and s ...
... LPS induction. In addition, short-term treatment with the inhibitor of transcriptional elongation, 5,6-dichloro-1-b-D-ribofuranosyl-benzimidazole, permitted transcription of many immediate-early genes but abrogated LPS-induced LINoCR expression, IKKa recruitment, histone H3 phosphoacetylation, and s ...