Table S1.
... resistant than heterozygotes; directional selection cannot be excluded [6]. In addition, α-thalassemia alleles are also associated with other infectious diseases [6] e.g. Thalassemic children in Vanuatu more susceptible to infection with Plasmodium vivax. Subsequent immune response renders them rela ...
... resistant than heterozygotes; directional selection cannot be excluded [6]. In addition, α-thalassemia alleles are also associated with other infectious diseases [6] e.g. Thalassemic children in Vanuatu more susceptible to infection with Plasmodium vivax. Subsequent immune response renders them rela ...
A Genomic Imprinting Test for Ordinal Traits in Pedigree Data
... generated 100 pedigrees with two parents and three offspring in each pedigree. A latent variable Uie was generated from N(0,1) that is shared by all family members, and a random noise eij was also generated from N(0,1) for each individual. For each founder in a pedigree, 20 highly polymorphic marker ...
... generated 100 pedigrees with two parents and three offspring in each pedigree. A latent variable Uie was generated from N(0,1) that is shared by all family members, and a random noise eij was also generated from N(0,1) for each individual. For each founder in a pedigree, 20 highly polymorphic marker ...
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genetics 7: e1002087.
... FGF, which activates Breathless FGFR and plays a central role in controlling and coupling each of these processes by guiding outgrowth of primary branches and inducing expression of key genes encoding transcription factors such as pointed, blistered/pruned, and escargot required, respectively, for s ...
... FGF, which activates Breathless FGFR and plays a central role in controlling and coupling each of these processes by guiding outgrowth of primary branches and inducing expression of key genes encoding transcription factors such as pointed, blistered/pruned, and escargot required, respectively, for s ...
Additional information on heterozygote advantage.
... resistant than heterozygotes; directional selection cannot be excluded [6]. In addition, α-thalassemia alleles are also associated with other infectious diseases [6] e.g. Thalassemic children in Vanuatu more susceptible to infection with Plasmodium vivax. Subsequent immune response renders them rela ...
... resistant than heterozygotes; directional selection cannot be excluded [6]. In addition, α-thalassemia alleles are also associated with other infectious diseases [6] e.g. Thalassemic children in Vanuatu more susceptible to infection with Plasmodium vivax. Subsequent immune response renders them rela ...
Supplementary Table Legends
... each sample, the Illumina instrument model, RIN score, type of run, and the number of total and uniquely-mapping reads is shown. In addition, it is indicated which percentage of quality-filtered reads mapped to exon, intron or intergenic coordinates, the number of Ensembl genes determined as express ...
... each sample, the Illumina instrument model, RIN score, type of run, and the number of total and uniquely-mapping reads is shown. In addition, it is indicated which percentage of quality-filtered reads mapped to exon, intron or intergenic coordinates, the number of Ensembl genes determined as express ...
Handout - 7 - Misc - Topics for discussion at June 2016
... codes created after the ACnc -> Pr/Threshold change). Still have about 7000 ACnc/Ord codes. As it turns out, it is very difficult to figure out whether an existing ACnc code should have the Property Pr versus Threshold, and even for new codes, the distinction is not always easy. Also, all else being ...
... codes created after the ACnc -> Pr/Threshold change). Still have about 7000 ACnc/Ord codes. As it turns out, it is very difficult to figure out whether an existing ACnc code should have the Property Pr versus Threshold, and even for new codes, the distinction is not always easy. Also, all else being ...
Mate choice evolution, dominance effects, and the
... Tomkins et al., 2004). Nevertheless, to enable us to track the coevolution of genetic variation and female choice, we have chosen to simplify the situation such that only one locus with two alleles, say A and a, determines the condition of both males and females (see Table 1 for a list of symbols). ...
... Tomkins et al., 2004). Nevertheless, to enable us to track the coevolution of genetic variation and female choice, we have chosen to simplify the situation such that only one locus with two alleles, say A and a, determines the condition of both males and females (see Table 1 for a list of symbols). ...
introduction to genetic epidemiology
... The heuristic interpretation is that aggregation exists when cases of disease appear in families more often than one would expect if diseased cases were spread uniformly and randomly over individuals: “it runs in the family” Actual approaches for detecting aggregation depend on the nature of the ...
... The heuristic interpretation is that aggregation exists when cases of disease appear in families more often than one would expect if diseased cases were spread uniformly and randomly over individuals: “it runs in the family” Actual approaches for detecting aggregation depend on the nature of the ...
An In Silico Investigation Into the Discovery of Novel Cis
... the tumor-specific expression patterns correspond to expression patterns in corresponding embryonic cell lineages. The intronic regions of the PAX7 gene were analyzed using computational DNA pattern recognition methods. Several potential cis-regulatory motifs were identified in this investigation an ...
... the tumor-specific expression patterns correspond to expression patterns in corresponding embryonic cell lineages. The intronic regions of the PAX7 gene were analyzed using computational DNA pattern recognition methods. Several potential cis-regulatory motifs were identified in this investigation an ...
The global repressor FliZ antagonizes gene
... S2A) (21,22) and recent publications indicate that FliZ acts as a DNA-binding regulator in other bacterial species (23). This suggested that the ability of FliZ to antagonize sS-dependent gene expression (10) might be due to binding to sS-controlled promoters rather than to sS itself. This possibili ...
... S2A) (21,22) and recent publications indicate that FliZ acts as a DNA-binding regulator in other bacterial species (23). This suggested that the ability of FliZ to antagonize sS-dependent gene expression (10) might be due to binding to sS-controlled promoters rather than to sS itself. This possibili ...
Full Text - Genes | Genomes | Genetics
... mice do not recapitulate the severe human (and canine) phenotypes (Cooper et al. 1988; Valentine et al. 1988, 1992). Many other cases of muscular dystrophies in dogs and other companion animals have been published. Recently, the case of a myopathic Labrador Retriever was reported that showed greatly ...
... mice do not recapitulate the severe human (and canine) phenotypes (Cooper et al. 1988; Valentine et al. 1988, 1992). Many other cases of muscular dystrophies in dogs and other companion animals have been published. Recently, the case of a myopathic Labrador Retriever was reported that showed greatly ...
Fungal - CBS-KNAW Fungal Biodiversity Centre
... appears that other Cercospora species may also occur on this host (Wang et al., 1998). The unnamed Cercospora sp. reported by Crous et al. (2006) appeared to be morphologically and phylogenetically more similar to isolates in the C. apii complex than to C. zeae-maydis and C. zeina. The description o ...
... appears that other Cercospora species may also occur on this host (Wang et al., 1998). The unnamed Cercospora sp. reported by Crous et al. (2006) appeared to be morphologically and phylogenetically more similar to isolates in the C. apii complex than to C. zeae-maydis and C. zeina. The description o ...
What are SNPs
... SNP Validation refers to genetic validation, the process of ensuring that the SNP is not due to sequencing error and that it is not extremely rear. This should not be confused with assay, target or regulatory validation. Confirmation of SNPs found in Discovery Larger numbers of individual samples to ...
... SNP Validation refers to genetic validation, the process of ensuring that the SNP is not due to sequencing error and that it is not extremely rear. This should not be confused with assay, target or regulatory validation. Confirmation of SNPs found in Discovery Larger numbers of individual samples to ...
2002-11-19: Quantitative Traits V
... Experiment can be designed to remove such crossed genotype by environment covariance. One can assume these covariance terms are nonzero. If they are not, they are absorbed in the genetic variance. ...
... Experiment can be designed to remove such crossed genotype by environment covariance. One can assume these covariance terms are nonzero. If they are not, they are absorbed in the genetic variance. ...
Molecular Evolution of Overlapping Genes
... limitations, and compare the possible outcomes of estimating selection without ...
... limitations, and compare the possible outcomes of estimating selection without ...
Meiosis and Sexual Life Cycles
... In synapsis, the 2 members of each homologous pair of chromosomes line up side-by-side, aligned gene by gene, to form a tetrad consisting of 4 chromatids During synapsis, sometimes there is an exchange of homologous parts between non-sister chromatids. This exchange is called crossing over Each tetr ...
... In synapsis, the 2 members of each homologous pair of chromosomes line up side-by-side, aligned gene by gene, to form a tetrad consisting of 4 chromatids During synapsis, sometimes there is an exchange of homologous parts between non-sister chromatids. This exchange is called crossing over Each tetr ...
Garrett-Engele* C. M., Siegal*, M. L., Manoli, D. S., Williams, B. C., Li. H., and Baker, B. S.
... length polymorphism (RFLP) mapping. A clone containing the ix gene was identified by its ability to rescue ix mutant phenotypes when introduced into flies by P-element-mediated germline transformation. The ix protein has sequence similarity to proteins proposed to act as transcriptional activators, ...
... length polymorphism (RFLP) mapping. A clone containing the ix gene was identified by its ability to rescue ix mutant phenotypes when introduced into flies by P-element-mediated germline transformation. The ix protein has sequence similarity to proteins proposed to act as transcriptional activators, ...
Genes, Chromosomes, and Numbers
... • Finally nuclei, reform, the spindles break down, and the cytoplasm divides. • At the end of meiosis II, four haploid cells have been formed from one diploid cell. ...
... • Finally nuclei, reform, the spindles break down, and the cytoplasm divides. • At the end of meiosis II, four haploid cells have been formed from one diploid cell. ...
Foot-and-mouth disease type O viruses exhibit genetically and
... Serotype O is the most prevalent of the seven serotypes of foot-and-mouth disease (FMD) virus and occurs in many parts of the world. The UPGMA method was used to construct a phylogenetic tree based on nucleotide sequences at the 3h end of the VP1 gene from 105 FMD type O viruses obtained from sample ...
... Serotype O is the most prevalent of the seven serotypes of foot-and-mouth disease (FMD) virus and occurs in many parts of the world. The UPGMA method was used to construct a phylogenetic tree based on nucleotide sequences at the 3h end of the VP1 gene from 105 FMD type O viruses obtained from sample ...
Exam 2
... 4. It is possible to eliminate the tetracycline resistant (TetR) plasmid pLAFR from a bacterial strain by mating in the gentamycin resistant (GenR) plasmid pPH1JI. a. What does this suggest about the properties of these two plasmids? ANSWER: The two plasmids are probably incompatible. This means tha ...
... 4. It is possible to eliminate the tetracycline resistant (TetR) plasmid pLAFR from a bacterial strain by mating in the gentamycin resistant (GenR) plasmid pPH1JI. a. What does this suggest about the properties of these two plasmids? ANSWER: The two plasmids are probably incompatible. This means tha ...
Lung Cancer - American Thoracic Society
... Epidemiologic research has vastly improved our understanding of lung cancer risk factors and found them to be modifiable with appropriate interventions. Lung cancer is much less common in persons without identifiable risk factors. Applying this information to develop and implement prevention strateg ...
... Epidemiologic research has vastly improved our understanding of lung cancer risk factors and found them to be modifiable with appropriate interventions. Lung cancer is much less common in persons without identifiable risk factors. Applying this information to develop and implement prevention strateg ...
trans - bioRxiv
... these effects in downstream analyses did not change our conclusions, but we nonetheless excluded these ...
... these effects in downstream analyses did not change our conclusions, but we nonetheless excluded these ...
Proceedings as -file
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
... Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
Genomic Predictors of Outcome in Prostate Cancer
... of the topic and recent high-quality reviews, we have specifically focused on genomic tests that are already available or approaching the point of clinical use [4–10]. ...
... of the topic and recent high-quality reviews, we have specifically focused on genomic tests that are already available or approaching the point of clinical use [4–10]. ...