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Antidepressant switching
Antidepressant switching

... of depressive disorders because of the perception that they do not cause major adverse reactions either in therapeutic doses or overdose. Since the introduction of these agents, the risk of severe cardiotoxicity (as seen with TCAs) seems to have decreased, but there have been increasing reports of o ...
Quick Reference Guide
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... restraint need to be established and maintained. It is important to ensure that suitable medications are available for use in these situations and are readily accessible. 2. Identify patients who need referral: referral systems need to be clearly established and communicated. It is recommended that ...
Efficacy and Safety of Lisdexamfetamine for Treatment of Adults With
Efficacy and Safety of Lisdexamfetamine for Treatment of Adults With

... Treatment with the antiobesity agent sibutramine hydrochloride demonstrated some efficacy in clinical trials; however, safety concerns led to market withdrawal.3,14-16 Antiepileptics also have been studied for BED, although they are associated with high rates of discontinuation.3,17,18 The most exte ...
Diagnostic and Management Guidelines for Mental Disorders in
Diagnostic and Management Guidelines for Mental Disorders in

... level this means that primary care should cover all basic aspects of health. This book has been written to ensure that, at the level of service provision, mental health becomes an integral part of the primary care practice. Mental disorders are common in the primary care settings. They are more disa ...
Comorbid Depressive and Anxiety Disorders in 509 Individuals With
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... groups. In addition to attenuated psychotic symptoms, subjects at high risk for psychosis usually present with other clinical concerns. High levels of negative symptoms, significant impairments in academic performance and occupational functioning, and difficulties with interpersonal relationships as ...
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... by Scott and colleagues (Scott et al., 2006). They found that individuals who had experienced 12 or more illness episodes deteriorated with CBT, whereas those who had fewer than 12 episodes of illness improved with treatment. A post-hoc analysis of the study of Psychoeducation by Colom (2008), showe ...
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... reserve antidepressants for nonresponder depressives. A possible option is represented by quetiapine, which has been reported to be effective in the treatment of acute bipolar depression. In our practice, the rate of intolerance of quetiapine or other antipsychotics is high (more than half of patien ...
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... NMDA antagonist (MK-801) induced hyperlocomotion, whereas it had no effect on the hyperlocomotion induced by amphetamine, and it is discussed that its utility as antipsychotic drug should be further evaluated. Both cinnarizine and flunarizine were able to reduce the hyperlocomotion induced by MK-801 ...
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Diagnosis and Management of Generalized Anxiety Disorder and

... tive to caffeine than the general population 5. Feelings of choking. because of genetic polymorphisms in adenos6. Chest pain or discomfort. ine receptors.14 Smoking cessation leads to 7. Nausea or abdominal distress. improved anxiety scores, with relapse lead8. Feeling dizzy, unsteady, light-hea ...
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The ICD-10 Classification of Mental and Behavioural Disorders
The ICD-10 Classification of Mental and Behavioural Disorders

... A psychotic disorder occurring during or immediately after drug use (usually within 48 hours) should be recorded here provided that it is not a manifestation of drugwithdrawal state with delirium (see F1x.4) or of late onset. Late-onset psychotic disorders (with onset more than 2 weeks after substa ...
Evidence-Based Treatment for Pediatric Obsessive-Compulsive Disorder Lindsay Brauer, MA, Adam B. Lewin, PhD,
Evidence-Based Treatment for Pediatric Obsessive-Compulsive Disorder Lindsay Brauer, MA, Adam B. Lewin, PhD,

... concern that many youth will remain symptomatic following an adequate medication course, many SRIs are associated with adverse events which may lead to treatment discontinuation (31, 34, 36) and some families do not find SRI therapy an acceptable intervention (40). In addition, there are few SRI mai ...
Statement of Principles concerning BIPOLAR DISORDER No. 25 of
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... in excess of what would be expected given the type or amount of the substance used or the duration of use; or there is other evidence that suggests the existence of an independent non-substance-induced mood disorder (e.g., a history of recurrent major depressive episodes). ...
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...  Overview and Defining Features  More chronic version of bipolar disorder  Manic and major depressive episodes are less severe  Manic or depressive mood states persist for long periods  Pattern must last for at least 2 years (1 year for children and adolescents)  Facts and Statistics  Average ...
The hidden third: improving outcome in treatment
The hidden third: improving outcome in treatment

... mental disorders (Figure 1) (Wittchen and Jacobi, 2005). Furthermore, MDD in Europe is often under-diagnosed and under-treated, for reasons including, among others, a lack of awareness, stigma, diagnostic problems and inadequate treatment (Arbabzadeh-Bouchez et al., 2002; Lecrubier, 2007). Even in p ...
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Antipsychotic



Antipsychotics (also known as neuroleptics or major tranquilizers) are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, or disordered thought), in particular in schizophrenia and bipolar disorder, and are increasingly being used in the management of non-psychotic disorders (ATC code N05A). The word neuroleptic originates from the Greek word νεῦρον neuron (""nerve"") and λῆψις lepsis (""seizure"", ""fit"", ""occupation"").First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second-generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's dopamine pathways, but atypicals tend to act on serotonin receptors as well.Antipsychotics are more effective than placebo in treating symptoms of psychosis, but some people do not respond fully or even partly to treatment. Their use is associated with significant side effects, most notably movement disorders and weight gain.
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