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101KB - NZQA
101KB - NZQA

... Independent assortment: Eg, when (homologous) pairs of chromosomes line up / separate randomly (either homologous or pairs acceptable), the arrangement is random. Mutation, (permanent) change in the (base sequence of) DNA. Explains why mutations produce new alleles. Mutations are a random change to ...
11.3 Notes
11.3 Notes

... TETRAD ...
outline29476
outline29476

... C. Most normal phenotypic differences among individuals are due to multifactorial inheritance. This includes differences in height, hair and skin color, and intelligence. D. Clinical characteristics of complex disorders. 1. These disorders can be common (> 1/5000 births). 2. The disorder tends to be ...
ppt - Villanova Computer Science
ppt - Villanova Computer Science

... survive, breed, and thereby pass their genes on to the next generation. GAs use a similar approach, but unlike nature, the size of the chromosome population remains unchanged from one generation to the next.  The last column in Table shows the ratio of the individual chromosome’s fitness to the pop ...
Chromosomal Microarray Analysis
Chromosomal Microarray Analysis

... – This means that a change was found, but there is little or no medical knowledge about the particular change. Whether the change may lead to medical problems and what types of problems it may cause is uncertain. In this case additional testing is performed, including analysis of DNA from the parent ...
chapter13_Sections 4-6
chapter13_Sections 4-6

... homologous chromosomes in the nucleus of a diploid (2n) reproductive cell. Maternal and paternal chromosomes, shown in pink and blue, have already been duplicated. B Either chromosome of a pair may get attached to either spindle pole during meiosis I. With two pairs of homologous chromosomes, there ...
Name Date__________ Period ______
Name Date__________ Period ______

...  Since the X and Y chromosomes carry different information, any genes found on the X chromosomes are referred to as _________________________________________________________. Therefore, women will have _________alleles for these genes because they have two (XX) chromosomes. On the other hand, men h ...
Exercise 11 - Genetics - Lake
Exercise 11 - Genetics - Lake

... The parents (“Rr” and “Rr”) are the F1 generation and were obtained from the P generation cross of a homozygous dominant (“RR”) and recessive (“rr”) individual. The offspring (“RR, ‘Rr”, “rr”) are then the F2 generation. This cross results in a mixture of phenotypes in the F2 generation. Most of the ...
Genetics - Montville.net
Genetics - Montville.net

... mark or alter the hereditary makeup of an unborn child. 3. Color blindness is more common in males than in females. 4. A person may transmit characteristics to offspring which he/she does not show. 5. Certain inherited traits may be altered by the stars, planets or moon early in development. 6. The ...
Notes on Mitosis and Meiosis
Notes on Mitosis and Meiosis

... 2) Meiosis mixes the forms of each gene that each sex cell (egg or sperm) receives. This makes for a lot of genetic diversity. This trick is accomplished through independent assortment and crossing-over. ...
Genetics Part I - Napa Valley College
Genetics Part I - Napa Valley College

...  Even though people could see this in nature and in agricultural breeding programs, they still believed in the blending theory. ...
Introduction_to_Human_Genetics
Introduction_to_Human_Genetics

... All daughters of an affected male and a normal female are affected (100%) All sons of an affected male and a normal female are normal (100%) Mating of affected females and normal males produce 1/2 the sons affected and 1/2 the daughters affected (50% :50%) Males are usually more severely affected th ...
DNA and Gene Expression - Department of Psychology
DNA and Gene Expression - Department of Psychology

... • Also, math disorder (moderate heritability from twin studies) co-occurs with reading disorder • Sibs and parents of reading-disabled probands do worse on tests of reading ability • Study of 250 twins with one reading disabled: 66% concordance for MZ, 36% for DZ ...
Topic 6 – Dihybrid crosses and Polygenic traits Dihybrid cross
Topic 6 – Dihybrid crosses and Polygenic traits Dihybrid cross

... ­ Complementary interaction – when two different genotypes interact to produce a phenotype  that neither is capable of producing itself n Ex. Combs of chickens  o R allele produces a rose comb o P allele produces a pea comb o R and P alleles together produce a walnut comb ...
Solid Tumour Section Thyroid: Papillary carcinoma Atlas of Genetics and Cytogenetics
Solid Tumour Section Thyroid: Papillary carcinoma Atlas of Genetics and Cytogenetics

... NTRK1, has been found in two other papillary thyroid tumors; although the two rearrangements involve different genomic regions of the partner genes, they occur in the same intron of both TPR and NTRK1; as a consequence, the same mRNA and 1323 aminoacid oncoprotein are produced and designated TRK-T2 ...
dragon genetics lab
dragon genetics lab

... page, for a total of 36 strips per page.) Apply rubber cement or Elmer's glue to both sides of a popsicle stick, and glue strips on both sides of the popsicle stick, continuing this until all the strips have been used to make popsicle stick chromosomes. For the autosomes and for the sex chromosomes ...
Genetic and Molecular Abnormalities in Tumors of the Bone and Soft
Genetic and Molecular Abnormalities in Tumors of the Bone and Soft

... or MDM2 genes. It has also been reported that the absence of MDM2 and p53 immunoreactivity in lipomas may be used in the differential diagnosis from well-differentiated liposarcoma lipoma-like (WDLPS).6 The WDLPS/atypical lipoma group is characterized by an extra ring and/or an extra giant chromosom ...
Faster-Z Evolution Is Predominantly Due to Genetic Drift Research
Faster-Z Evolution Is Predominantly Due to Genetic Drift Research

... org), and all probes that mapped either to the Z chromosome or autosomes were used in subsequent analysis. Sexbiased expression was defined as log2 (average male expression)/(average female expression), resulting in positive values for male-biased genes and negative values for femalebiased genes. Th ...
Document
Document

... Incomplete Dominance: Occurs when neither allele is dominant. They both have an affect on the heterozygous individual which shows a phenotype between the two homozygous phenotypes. Law of Dominance: If two alleles in a gene pair are different, then one allele can control and the other can be hidden. ...
SNP Analysis (GAW15 data)
SNP Analysis (GAW15 data)

... the MHC region makes the largest single contribution (relative recurrence risk ~1.8 ) to disease susceptibility7 A set of alleles at the DRB1 locus, many of which share a common polymorphic sequence, the “shared epitope”, explain a large portion, but not all, of the genetic risk within the MHC. ...
Control of Chromosome Pairing and Genome Evolution in Disomic
Control of Chromosome Pairing and Genome Evolution in Disomic

... They suggested the following mechanisms for the observed results: They suggested the following mechanisms for the observed results: “The changes we observed could have resulted from several different processes, such as chromosome rearrangement, point mutation, gene conversion, DNA methylation, and o ...
LOCATION OF THE CENTROMERES ON THE LINKAGE
LOCATION OF THE CENTROMERES ON THE LINKAGE

... percent or less. Proven crossovers with Y have not yet been obtained for study. With so much suppression of crossing over, little can be inferred as to the location of the Y locus with reference to the centromere. Translocations in the satellite or nucleola,r region have given less than 2 0 percent ...
Microsoft Word 97 - 2003 Document
Microsoft Word 97 - 2003 Document

... individual traits as having a possible maximum of two expressions. However, Mendel and geneticists after him found that some traits or phenotypes were controlled by more than two genes. Some individual traits were found to be affected by 3, 4 or even more genes. Phenotypes or traits affected by more ...
Teacher notes and student sheets
Teacher notes and student sheets

... explains evolution is natural selection. There is always variation between individuals in the same species. Some individuals will have characteristics which give them a better chance of surviving in a particular environment. Those individuals that survive will reproduce and pass on their characteris ...
Patterns of Inheritance
Patterns of Inheritance

... produce only one type of gamete; also called “pure.” Heterozygous: The condition in which two alternate forms (alleles) of a gene are contained within the organism, e.g. Rr; also called “hybrid.” Monohybrid cross: a cross (mating) involving a single trait. Dihybrid cross: a cross (mating) ...
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Skewed X-inactivation

Skewed X chromosome inactivation occurs when the inactivation of one X chromosome is favored over the other, leading to an uneven number of cells with each chromosome inactivated. It is usually defined as one allele being found on the active X chromosome in over 75% of cells, and extreme skewing is when over 90% of cells have inactivated the same X chromosome. It can be caused by primary nonrandom inactivation, either by chance due to a small cell pool or directed by genes, or caused by secondary nonrandom inactivation, which occurs by selection. Most females will have some levels of skewing. It is relatively common in adult females; around 35% of women have skewed ratio over 70:30, and 7% of women have an extreme skewed ratio of over 90:10. This is of medical significance due to the potential for the expression of disease genes present on the X chromosome that are normally not expressed due to random X inactivation. X chromosome inactivation occurs in females to provide dosage compensation between the sexes. If females kept both X chromosomes active they would have twice the number of active X genes than males, who only have one copy of the X chromosome. At approximately the time of implantation (see Implantation (human embryo), one of the two X chromosomes is randomly selected for inactivation. The cell undergoes transcriptional and epigenetic changes to ensure this inactivation is permanent. All progeny from these initial cells will maintain the inactivation of the same chromosome, resulting in a mosaic pattern of cells in females.
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