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miRNA pptx - NUS School of Computing
miRNA pptx - NUS School of Computing

... use the expression level of a known target genes for that specific intergenic miRNA If its target genes are consistently down-regulated, then we can assume that the expression level of the intergenic miRNA gene is up-regulated ...
Module 1: Introduction
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... GO Structure • Terms are related within a hierarchy – is-a – part-of ...
RNA Interference and Small Interfering RNAs
RNA Interference and Small Interfering RNAs

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BioACTS Quarter THREE
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An Introduction to Streptomyces
An Introduction to Streptomyces

... 8,667,507bp, and 7,825 predicted genes making it one of the largest bacterial genome to be sequenced to date. It is nearly twice the size of Escherichia coli (Blattner, 1997), Bacillus subtilis (Kunst, 1997) and Mycobacterium tuberculosis (Cole, 1998). It also has a greater number of genes than the ...
Identification of Quantitative Trait Loci That Affect Aggressive
Identification of Quantitative Trait Loci That Affect Aggressive

... (Lynch and Walsh, 1998), i.e., a binary variable, that was defined by the presence or absence of reproducible attack behavior; we chose not to measure aggression as a score based on a composite of various behaviors, because other behaviors, such as tail rattling, are only weakly correlated with atta ...
Review Process - The EMBO Journal
Review Process - The EMBO Journal

... interactions among other insulator DNA-binding proteins. Its own binding to chromatin seems to be in some cases dependent on other insulator proteins and in other cases independent. In this work, the authors have asked if CP190 associates with proteins that might explain its chromatin binding behavi ...
A gene expression atlas of a bicoid-depleted
A gene expression atlas of a bicoid-depleted

... License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. ...
XSL Formatter - H:\XML
XSL Formatter - H:\XML

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Chromatin Signature Identifies Monoallelic Gene Expression Across
Chromatin Signature Identifies Monoallelic Gene Expression Across

... genes predicted as MAE in GM12878 showed only minor changes compared to our previous study, consistent with the use of slightly different ChIP-Seq datasets. To note, in this context, the use of quantile rank is equivalent to quantile normalization, but without requiring a reference dataset. Conseque ...


... The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles (“cards”) on genes, leukaemias, solid tumours, canc ...
SB2. Students will analyze how biological traits are passed on to
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... have a positive effect these are called beneficial mutations. • These mutations lead to new versions of proteins that help an organism and its future generations better adapt to changes in their environment. • Example: – Deletion of CCR5 gene leads to HIV resistance – Found in European descent – Bel ...
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... The CATALYST is to be done independently and silently. Answer the following questions in your notebook: ...
Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE
Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE

... inherited recessively, we need to take a quantitative look at protein function. With the exception of sex-linked genes, diploid individuals have two copies of every gene. In a simple dominant/ recessive relationship, the recessive allele does not affect the phenotype of the heterozygote. In other wo ...
chapter 12 powerpoint notes
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Creating conditional dual fluorescence labelled transgenic animals
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Genetics of Primary ciliary dyskinesia - HAL
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... Thanks to a genetic linkage analysis performed in one large consanguineous multiplex family, mutations have been identified in a second gene encoding a dynein heavy chain, DNAH5 33 34. DNAH5, located on chromosome 5, codes for a protein orthologous of the Chlamydomonas axonemal heavy chain of the O ...
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Prader-Willi and Angelman syndromes: Sister imprinted disorders

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Gene Expression in Prokaryotes

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Functions of the nonsense-mediated RNA decay pathway in Drosophila development. PLoS Genetics 2 , 2143-2154.

... Upf1 and Upf2 are broadly active during development, and they are required for NMD as well as for proper expression of dozens of wild-type genes during development and for larval viability. Genetic mosaic analysis shows that Upf1 and Upf2 are required for growth and/or survival of imaginal cell clon ...
Scenario 3 - People.vcu.edu
Scenario 3 - People.vcu.edu

... Evidently no human has touched this annotation (System is given as the only source). Is the functional annotation sound? Mouse over* to the blue motif bar above the graphical representation of all1290. *In real life, information will pop up when you mouse to an informative position. In this simulati ...
GENE EXPRESSION
GENE EXPRESSION

... Chapter Fourteen Gene Expression: Control in Prokaryotes and Phages ...
Genetics chapt10
Genetics chapt10

... The allele for dark hair dominates the allele for light hair. If both parents are heterozygous for earlobe shape and hair color, what types of offspring can they produce, and what is the probability for each type? Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or di ...
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X-inactivation



X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated. The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes, X-inactivation prevents them from having twice as many X chromosome gene products as males, who only possess a single copy of the X chromosome (see dosage compensation). The choice of which X chromosome will be inactivated is random in placental mammals such as humans, but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cell and its descendants in the organism. Unlike the random X-inactivation in placental mammals, inactivation in marsupials applies exclusively to the paternally derived X chromosome.
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