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BMC Research Notes
BMC Research Notes

... Background: THP-1 is a human monocytic leukemia cell line derived from a patient with acute monocytic leukemia. The cell line differentiates into macrophage-like cells by stimulation with phorbol myristate acetate (PMA). Although it has been used frequently as a model for macrophage differentiation ...
Chapter 6 - kespinosa
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A family of human Y chromosomes has dispersed throughout
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... the regions involved in the first homologous recombination events in the two pathways. (B) FISH probes hybridized to interphase nuclei from a man (PD223) whose STS results are consistent with the reference sequence in (A). Hybridization with the green and red probes produced the expected pattern: gr ...
Practice Test - Cardinal Newman High School
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Evolutionary Computation in High Energy Physics
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... Note: Although FISH with a probe to the RUNX1 (AML1) gene is required to accurately identify this abnormality, the duplicated chromosome 21 is easily visible using conventional cytogenetics. The morphology of the abnormal chromosome 21 is highly heterogeneous presenting as a metacentric, acrocentric ...
Standard B-4: The student will demonstrate an understanding of the
Standard B-4: The student will demonstrate an understanding of the

... these are known as sex chromosomes. All other chromosomes are known as autosomal chromosomes, or autosomes. ○ Cells (except for sex cells) contain one pair of each type of chromosome.  Each pair consists of two chromosomes that have genes for the same proteins.  One chromosome in each pair was inh ...
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Student Note Packet
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Chavis Biology
Chavis Biology

... these are known as sex chromosomes. All other chromosomes are known as autosomal chromosomes, or autosomes. ○ Cells (except for sex cells) contain one pair of each type of chromosome.  Each pair consists of two chromosomes that have genes for the same proteins.  One chromosome in each pair was inh ...
Standard B-4: The student will demonstrate an
Standard B-4: The student will demonstrate an

... these are known as sex chromosomes. All other chromosomes are known as autosomal chromosomes, or autosomes. ○ Cells (except for sex cells) contain one pair of each type of chromosome. ♦ Each pair consists of two chromosomes that have genes for the same proteins. ♦ One chromosome in each pair was inh ...
Inheritance - CCRI Faculty Web
Inheritance - CCRI Faculty Web

... Mutations • Changes to the nucleotide sequence of the genetic material of an organism • Can be caused by: ...
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Karyotype



A karyotype (from Greek κάρυον karyon, ""kernel"", ""seed"", or ""nucleus"", and τύπος typos, ""general form"") is the number and appearance of chromosomes in the nucleus of a eukaryotic cell. The term is also used for the complete set of chromosomes in a species, or an individual organism.Karyotypes describe the chromosome count of an organism, and what these chromosomes look like under a light microscope. Attention is paid to their length, the position of the centromeres, banding pattern, any differences between the sex chromosomes, and any other physical characteristics. The preparation and study of karyotypes is part of cytogenetics. The study of whole sets of chromosomes is sometimes known as karyology. The chromosomes are depicted (by rearranging a photomicrograph) in a standard format known as a karyogram or idiogram: in pairs, ordered by size and position of centromere for chromosomes of the same size.The basic number of chromosomes in the somatic cells of an individual or a species is called the somatic number and is designated 2n. Thus, in humans 2n = 46. In the germ-line (the sex cells) the chromosome number is n (humans: n = 23).p28So, in normal diploid organisms, autosomal chromosomes are present in two copies. There may, or may not, be sex chromosomes. Polyploid cells have multiple copies of chromosomes and haploid cells have single copies.The study of karyotypes is important for cell biology and genetics, and the results may be used in evolutionary biology (karyosystematics) and medicine. Karyotypes can be used for many purposes; such as to study chromosomal aberrations, cellular function, taxonomic relationships, and to gather information about past evolutionary events.
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