Public Assessment Report Decentralised Procedure Levofloxacin 250 mg and 500 mg Film-coated
... fluoroquinolones, including levofloxacin, which can be rapid in its onset. Levofloxacin should be discontinued if the patient experiences symptoms of neuropathy in order to prevent the development of an irreversible condition. Opiates In patients treated with levofloxacin, determination of opiates i ...
... fluoroquinolones, including levofloxacin, which can be rapid in its onset. Levofloxacin should be discontinued if the patient experiences symptoms of neuropathy in order to prevent the development of an irreversible condition. Opiates In patients treated with levofloxacin, determination of opiates i ...
Product Monograph Template - Standard
... administering this drug to patients with hepatic impairment. KALETRA® has not been studied in patients with severe hepatic impairment. Pharmacokinetic data suggests increases in lopinavir plasma concentrations of approximately 30% as well as decreases in plasma protein binding in HIV and hepatitis C ...
... administering this drug to patients with hepatic impairment. KALETRA® has not been studied in patients with severe hepatic impairment. Pharmacokinetic data suggests increases in lopinavir plasma concentrations of approximately 30% as well as decreases in plasma protein binding in HIV and hepatitis C ...
Hydrocodone Bitartrate and Acetaminophen Tablets, USP
... Assess each patient’s risk for opioid addiction, abuse, or misuse prior to prescribing Hydrocodone Bitartrate and Acetaminophen Tablets, and monitor all patients receiving Hydrocodone Bitartrate and Acetaminophen Tablets for the development of these behaviors and conditions. Risks are increased in p ...
... Assess each patient’s risk for opioid addiction, abuse, or misuse prior to prescribing Hydrocodone Bitartrate and Acetaminophen Tablets, and monitor all patients receiving Hydrocodone Bitartrate and Acetaminophen Tablets for the development of these behaviors and conditions. Risks are increased in p ...
PRODUCT MONOGRAPH UNIPHYL Theophylline Sustained
... Therefore, it is advisable to individualize the dosage regimen. Ideally, all patients should have serum theophylline levels measured which would enable doses and dosing regimens to be tailored for each patient in order to maintain therapeutic levels, ensure optimal clinical response and avoid toxici ...
... Therefore, it is advisable to individualize the dosage regimen. Ideally, all patients should have serum theophylline levels measured which would enable doses and dosing regimens to be tailored for each patient in order to maintain therapeutic levels, ensure optimal clinical response and avoid toxici ...
SALT SOLID DISPERSIONS
... accepted approach to improve dissolution rate of poorly water-soluble ionic drugs. Nevertheless, the salt formation process is often empirical and may not always lead to desired end product profile. Alternatively, pH-modifiers have been used as formulation components for such compounds. The purpose ...
... accepted approach to improve dissolution rate of poorly water-soluble ionic drugs. Nevertheless, the salt formation process is often empirical and may not always lead to desired end product profile. Alternatively, pH-modifiers have been used as formulation components for such compounds. The purpose ...
Product Monograph CEFTIN
... Clostridium difficile-associated disease (CDAD) has been reported with use of many antibacterial agents including CEFTIN® (see ADVERSE REACTIONS). CDAD may range in severity from mild diarrhea to fatal colitis. It is important to consider this diagnosis in patients who present with diarrhea, or symp ...
... Clostridium difficile-associated disease (CDAD) has been reported with use of many antibacterial agents including CEFTIN® (see ADVERSE REACTIONS). CDAD may range in severity from mild diarrhea to fatal colitis. It is important to consider this diagnosis in patients who present with diarrhea, or symp ...
Full Text PDF - International Journal of ChemTech Research
... Antacids are agents that react with protons in the lumen of the gut. The use of antacids effectively reduce peptic ulcers occurrence when used regularly in large doses which are to raise stomach pH. Aluminum compound also stimulates protective functions of gastric mucosa. 4 Conventional antacids hav ...
... Antacids are agents that react with protons in the lumen of the gut. The use of antacids effectively reduce peptic ulcers occurrence when used regularly in large doses which are to raise stomach pH. Aluminum compound also stimulates protective functions of gastric mucosa. 4 Conventional antacids hav ...
STAXYN PRODUCT MONOGRAPH
... advised to contact their physician for dose adjustment if they are not satisfied with the quality of their erection or if they have an undesirable effect as vardenafil in film-coated tablets are available in other strengths. Patients should be counselled about the importance of notifying their phys ...
... advised to contact their physician for dose adjustment if they are not satisfied with the quality of their erection or if they have an undesirable effect as vardenafil in film-coated tablets are available in other strengths. Patients should be counselled about the importance of notifying their phys ...
Hydroxyzine Dihydrochloride
... Caution is needed in patients who have a known predisposing factor to cardiac arrhythmia, including electrolytes imbalance (hypokalaemia, hypomagnesaemia), who have pre-existing heart disease, or who are concomitantly treated with a potentially arrhythmogenic drug. In these patients use of alternati ...
... Caution is needed in patients who have a known predisposing factor to cardiac arrhythmia, including electrolytes imbalance (hypokalaemia, hypomagnesaemia), who have pre-existing heart disease, or who are concomitantly treated with a potentially arrhythmogenic drug. In these patients use of alternati ...
Morphine Sulfate Extended-Release Tablets Page 1 of 22
... opioid, morphine sulfate extended-release tablets expose users to the risks of addiction, abuse, and misuse. As modified-release products such as morphine sulfate extended-release tablets deliver the opioid over an extended period of time, there is a greater risk for overdose and death due to the la ...
... opioid, morphine sulfate extended-release tablets expose users to the risks of addiction, abuse, and misuse. As modified-release products such as morphine sulfate extended-release tablets deliver the opioid over an extended period of time, there is a greater risk for overdose and death due to the la ...
VALIDATED HPLC METHOD FOR SIMULTANEOUS QUANTITATION OF TADALAFIL AND
... analysis data for the calibration plots showed a good linear relationship over the concentration range of 0.25-4 µg/mL for Tadalafil and 0.75-12 µg/mL for Dapoxetine Hydrochloride respectively. The mean values of the correlation coefficient, slope and intercept were 0.9995 ± 1.27, 133612 ± 0.72 and ...
... analysis data for the calibration plots showed a good linear relationship over the concentration range of 0.25-4 µg/mL for Tadalafil and 0.75-12 µg/mL for Dapoxetine Hydrochloride respectively. The mean values of the correlation coefficient, slope and intercept were 0.9995 ± 1.27, 133612 ± 0.72 and ...
... appropriate treatment measures should be established. Management of pseudomembranous colitis should include sigmoidoscopy, appropriate bacteriologic studies, fluids, electrolytes and protein supplementation. If the colitis does not improve after the drug has been discontinued, or if the symptoms are ...
SIMULTANEOUS ESTIMATION OF CETRIZINE HYDROCHLORIDE AND PHENYLPROPANOLAMINE HYDROCHLORIDE BY HIGH PERFORMANCE THIN LAYER
... determined by various pharmacopeial and non‐pharmacopeial methods. The pharmacopeial methods include potentiometric titration and liquid chromatographic method. Many liquid chromatography methods have been reported for the estimation of PPA alone in biological fluids and i ...
... determined by various pharmacopeial and non‐pharmacopeial methods. The pharmacopeial methods include potentiometric titration and liquid chromatographic method. Many liquid chromatography methods have been reported for the estimation of PPA alone in biological fluids and i ...
Pharmaceutical Technology
... 3. Process aids – Preservatives and surfactants are added to the gelatin solution during capsule manufacture to aid in processing. Gelatin solutions are an ideal medium for bacterial growth at temperatures below 55○ C. preservatives are added to the gelatin and colorant solutions to reduce the grow ...
... 3. Process aids – Preservatives and surfactants are added to the gelatin solution during capsule manufacture to aid in processing. Gelatin solutions are an ideal medium for bacterial growth at temperatures below 55○ C. preservatives are added to the gelatin and colorant solutions to reduce the grow ...
CARDOXIN doctor leaflet
... Pharmacodynamic properties Dipyridamole has an antithrombotic action based on its ability to modify various aspects of platelet function, such as platelet aggregation, adhesion and survival, which have been shown to be factors associated with the initiation of thrombus formation. Dipyridamole also h ...
... Pharmacodynamic properties Dipyridamole has an antithrombotic action based on its ability to modify various aspects of platelet function, such as platelet aggregation, adhesion and survival, which have been shown to be factors associated with the initiation of thrombus formation. Dipyridamole also h ...
maxzide
... Following oral administration, peak hydrochlorothiazide plasma levels are attained in approximately 2 hours. It is excreted rapidly and unchanged in the urine. Well controlled studies have demonstrated that doses of hydrochlorothiazide as low as 25 mg given once daily are effective in treating hyper ...
... Following oral administration, peak hydrochlorothiazide plasma levels are attained in approximately 2 hours. It is excreted rapidly and unchanged in the urine. Well controlled studies have demonstrated that doses of hydrochlorothiazide as low as 25 mg given once daily are effective in treating hyper ...
Amstan Tablets.FH11
... Amlodipine and Valsartan are antihypertensive compounds with complementary mechanisms to control blood pressure in patients with essential hypertension. The combination of these substances has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alon ...
... Amlodipine and Valsartan are antihypertensive compounds with complementary mechanisms to control blood pressure in patients with essential hypertension. The combination of these substances has an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alon ...
Oxycodone and Acetaminophen Tablets USP 5
... potential drug of abuse. They should protect it from theft, and it should never be given to anyone other than the individual for whom it was prescribed. Laboratory Tests Although oxycodone may cross-react with some drug urine tests, no available studies were found which determined the duration of de ...
... potential drug of abuse. They should protect it from theft, and it should never be given to anyone other than the individual for whom it was prescribed. Laboratory Tests Although oxycodone may cross-react with some drug urine tests, no available studies were found which determined the duration of de ...
SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME OF THE
... Posology and method of administration For oral use between injections, as a follow up to a course of injections and as prophylactic therapy. Adults and adolescents over 15 years: 1-2 tablets 1-3 times a day. Children over 7 years: 1 tablet once a day. Children under 7 years: on physician's prescript ...
... Posology and method of administration For oral use between injections, as a follow up to a course of injections and as prophylactic therapy. Adults and adolescents over 15 years: 1-2 tablets 1-3 times a day. Children over 7 years: 1 tablet once a day. Children under 7 years: on physician's prescript ...
Specials information pack - Barking and Dagenham Clinical
... Risk Hierarchy for the use of unlicensed medicines • An unlicensed product should not be used where a product available and licensed within the UK could be used to meet the patient's special need. • Although the MHRA does not recommend "off label" (outside of the licensed indications) use of produc ...
... Risk Hierarchy for the use of unlicensed medicines • An unlicensed product should not be used where a product available and licensed within the UK could be used to meet the patient's special need. • Although the MHRA does not recommend "off label" (outside of the licensed indications) use of produc ...
Azithromycin - Rebound Health
... been used to prevent bacterial infections in infants and those with weaker immune systems. It is also effective against certain venereal diseases, such as non-gonococcal urethritis, chlamydia, gonorrhea and cervicitis. Recent studies have also indicated it to be effective against late-onset asthma, ...
... been used to prevent bacterial infections in infants and those with weaker immune systems. It is also effective against certain venereal diseases, such as non-gonococcal urethritis, chlamydia, gonorrhea and cervicitis. Recent studies have also indicated it to be effective against late-onset asthma, ...
Zopiclone is a drug with very similar effects
... Zopiclone and Z-drugs Zopiclone is prescribed in tablet form, either as zopiclone or under the brand name Zimovane, which along with zolpidem (brand name Stilnoct) and zaleplon (brand name Sonata), are known as ‘Z drugs’ – that is, sleeping pills which begin with the letter ’z’. Zopiclone tablets go ...
... Zopiclone and Z-drugs Zopiclone is prescribed in tablet form, either as zopiclone or under the brand name Zimovane, which along with zolpidem (brand name Stilnoct) and zaleplon (brand name Sonata), are known as ‘Z drugs’ – that is, sleeping pills which begin with the letter ’z’. Zopiclone tablets go ...
Product Monograph
... compared with that of the fasting state and tend to cancel the effect of enhanced postprandial absorption. In common with other antibiotics, cefuroxime axetil may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives. Drug-Laboratory Test I ...
... compared with that of the fasting state and tend to cancel the effect of enhanced postprandial absorption. In common with other antibiotics, cefuroxime axetil may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives. Drug-Laboratory Test I ...
Thyroxine Sodium - Therapeutic Goods Administration
... Stability data were generated under accelerated and long-term conditions on batches packaged in the proposed container closure system (which includes a child-resistant closure). This would support a shelf life of 2 years when stored below 25ºC with the condition protect from light. The tablets are m ...
... Stability data were generated under accelerated and long-term conditions on batches packaged in the proposed container closure system (which includes a child-resistant closure). This would support a shelf life of 2 years when stored below 25ºC with the condition protect from light. The tablets are m ...
Australian public assessment for Thyroxine Sodium
... Stability data were generated under accelerated and long-term conditions on batches packaged in the proposed container closure system (which includes a child-resistant closure). This would support a shelf life of 2 years when stored below 25ºC with the condition protect from light. The tablets are m ...
... Stability data were generated under accelerated and long-term conditions on batches packaged in the proposed container closure system (which includes a child-resistant closure). This would support a shelf life of 2 years when stored below 25ºC with the condition protect from light. The tablets are m ...
Tablet (pharmacy)
A tablet is a pharmaceutical dosage form. Tablets may be defined as the solid unit dosage form of medicament or medicaments with or without suitable diluents and prepared either by molding or by compression. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.The compressed tablet is the most popular dosage form in use today. About two-thirds of all prescriptions are dispensed as solid dosage forms, and half of these are compressed tablets. A tablet can be formulated to deliver an accurate dosage to a specific site; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally. The tablet is just one of the many forms that an oral drug can take such as syrups, elixirs, suspensions, and emulsions. Medicinal tablets were originally made in the shape of a disk of whatever color their components determined, but are now made in many shapes and colors to help distinguish different medicines. Tablets are often stamped with symbols, letters, and numbers, which enable them to be identified. Sizes of tablets to be swallowed range from a few millimeters to about a centimeter.