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Mechanisms of drug resistance
Mechanisms of drug resistance

... • It seems that some resistance was already naturally present in bacterial populations • The presence of antibiotics in their environment in higher concentrations increased the pressure by natural selection • Resistant bacteria that survived, rapidly multiplied • They passed their resistant genes on ...
Penicillins
Penicillins

... Most are mild, but about 10% of allergic reactions are lifel-threatening ...
Bacterial Meningitis - UNC
Bacterial Meningitis - UNC

... of several antibiotics like penicillin and cephalosporins  Attack peptioglycans in bacterial cell walls ...
Neurologic Manifestations and Outcome of West Nile Virus Infection BRIEF REPORT
Neurologic Manifestations and Outcome of West Nile Virus Infection BRIEF REPORT

... manifest as a mild febrile illness, but a small proportion of patients (⬍1%) develop acute neurologic illness.1-4 Although recent WNV outbreaks have been associated with severe neurologic disease,1-5 retrospective studies have failed to identify clinical features that distinguish WNV from other vira ...
Empiric Treatment: Pneumonia
Empiric Treatment: Pneumonia

... Diagnosis of Meningitis • The CSF is then examined under a microscope to look for bacteria or fungi. Normal CSF contains set percentages of glucose and protein. These percentages will vary with bacterial, viral, or other causes of meningitis. For example, bacterial meningitis causes a greatly lower ...
Transplant Infectious Diseases - Vanderbilt University Medical Center
Transplant Infectious Diseases - Vanderbilt University Medical Center

... transplant for cystic fibrosis in 1993 in North Carolina. She was EBV seronegative at the time of transplantation. She converted to EBV after transplantation possible from the donor She maintained excellent lung function posttransplant. 13 years later she presented with a month of headache, low-grad ...
18.4 Bacteria and Archaea
18.4 Bacteria and Archaea

... • Archaebacteria are typically obligate anaerobes. • Live in extremely harsh environments, ex.stomachs of cows, high salt concentrated areas such as the Dead Sea and in sulfur springs or deep sea vents. ...
Previous macrolide exposure H. pylori success at risk choose PYlera® capsules plus omeprazole
Previous macrolide exposure H. pylori success at risk choose PYlera® capsules plus omeprazole

... Parameters Committee of the American College of Gastroenterology. American College of Gastroenterology Guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. 2007;102(8):1808-1825. 4. PYLERA® [package insert]. Birmingham, AL: Axcan Pharma US, Inc.; 2011. 5. Vakil N. Manage ...
MLS Laboratory Update: January 25, 2011 (PDF)
MLS Laboratory Update: January 25, 2011 (PDF)

... In June 2010, CLSI published new MIC and disk diffusion interpretive criteria (i.e., breakpoints) for the Enterobacteriaceae for five cephalosporins, including first-generation and third-generation (extendedspectrum) cephalosporins, aztreonam, and for three carbapenems (imipenem, meropenem, and erta ...
Indian J Nephrol
Indian J Nephrol

...  Sexually active women have a markedly increased risk of cystitis  Vast majority of acute symptomatic infections involve young women  A prospective study demonstrated an annual incidence of 0.5-0.7 episodes/patient year in this group  In the absence of prostatitis, bacteriuria and symptomatic UT ...
MRSA Parents and Schools Fact Sheet
MRSA Parents and Schools Fact Sheet

... Discourage sharing of towels and personal items such as clothing or equipment. Wash uniforms, clothes, towels, and sheets with water and laundry detergent after each use. Dry clothes in a hot dryer. Lockers, benches, showers, weight benches and other shared surfaces in athletic training facilities s ...
Understanding Asymptomatic Bacteriuria
Understanding Asymptomatic Bacteriuria

... 6. Warren J, et al. Fever, bacteremia, and death as complications of bacteriuria in women with long-term urethral catheters. J Infect Dis. 1987;155:1151-1158. 7. Stevens V, et al. Cumulative antibiotic exposures over time and the risk of Clostridium difficile infection. Clin Infect Dis. 2011;53:42-4 ...
ANTIBIOTIC RESISTANCE: ORIGINS, EVOLUTION, SELECTION
ANTIBIOTIC RESISTANCE: ORIGINS, EVOLUTION, SELECTION

... organisms as well. These normally harmless bacteria, such as E. coli or enterococcus, can cause a fatal illness if the person is immunocompromised. Moreover, these bacteria harbour resistance genes which can spread to the bacterial strains that do cause infection. Unfortunately, these reservoirs are ...
European Respiratory Society Annual Congress 2012
European Respiratory Society Annual Congress 2012

... [email protected] MD 3 and Dr. Hongqiu 7245 Pan [email protected] MD 4. 1 Department of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China, 210029 ; 2 Department of Chronic Infectious Diseases, Center for Disease Control and Prevention of Jia ...
Mechanism of Human Disease/ Infectious Disease
Mechanism of Human Disease/ Infectious Disease

... the nasopharynx. It performs three functions: ventilation, protection, and clearance via mucociliary transport. Viral upper respiratory infection or allergy causes inflammation and edema in the eustachian tube, impairing its normal functions. When ventilation of the middle ear is lost, oxygen is abs ...
Clinical Nutrition Week 2001: A Summary of Recommendations
Clinical Nutrition Week 2001: A Summary of Recommendations

... along with our nutrition support (TF/TPN) recommendations for appropriate patients Should we consider implementing protocols for glutamine and antioxidants in our facilities? Would a combination of supplementation with glutamine and antioxidants together be beneficial? ...
Strep Throat - St. Clair County
Strep Throat - St. Clair County

... The strep test will help the healthcare professional decide if a person needs antibiotics, which can: ...
Carbapenemase June 2015 programme and registration form.indd
Carbapenemase June 2015 programme and registration form.indd

... Carbapenemase-producing Gram-negatives have become a major concern worldwide. Many factors, including the ease of international travel for medical tourism and migration and the importation of food products, have been responsible for introducing these microorganisms to several countries far beyond th ...
Increase in transmitted resistance to non
Increase in transmitted resistance to non

... Methods: Clinical, epidemiological and virological data from 4317 patients newly diagnosed with HIV-1 infection between 2002 and 2007 were analysed. Patients were enrolled using a pre-defined sampling strategy. Results: The overall prevalence of TDRM in this period was 8.9% (95% CI: 8.1-9.8). Intere ...
Increase in transmitted resistance to non
Increase in transmitted resistance to non

... Methods: Clinical, epidemiological and virological data from 4317 patients newly diagnosed with HIV-1 infection between 2002 and 2007 were analysed. Patients were enrolled using a pre-defined sampling strategy. Results: The overall prevalence of TDRM in this period was 8.9% (95% CI: 8.1-9.8). Intere ...
VAP RN ICU
VAP RN ICU

...  Due to high incidence of SIRS and ARDS in ICU, the validity of a radiographic infiltrate becomes less reliable ...
Cross Infection in Dentistry
Cross Infection in Dentistry

... effectiveness can be limited by the standard of any of its members as well as the degree to which they can co-operate. The general recommendation is that dental work, such as impressions, gypsum casts, dentures, and wax registration records, should be disinfected at the clinic prior to sending them ...
Group A Streptococcal Infection - Sandwell and West Birmingham
Group A Streptococcal Infection - Sandwell and West Birmingham

... Close contacts of a person with GAS infection will also be given antibiotics if they have symptoms suggesting that they are also infected. If a mother or baby in the neonatal period (first 28 days of life) develops iGAS, both will be given antibiotics. Antibiotics may also be given as a control meas ...
APIC Text of Infection Control and Epidemiology
APIC Text of Infection Control and Epidemiology

... Although most resistance can be traced to the human behaviors that lie behind these forces, the development and spread of resistance also are greatly affected by certain microbial characteristics, such as the ease by which an organism can develop or acquire resistance traits. Infection prevention, b ...
Impetigo Fact Sheet
Impetigo Fact Sheet

... Antibiotics are prescribed to treat Impetigo and are given by mouth or a cream. It is important that this medication be used exactly as the doctor instructs. ...
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Carbapenem-resistant enterobacteriaceae

Carbapenem-resistant enterobacteriaceae (CRE) or Carbapenemase-producing Enterobacteriaceae (CPE), are gram-negative bacteria that are nearly resistant to the carbapenem class of antibiotics, considered the ""drug of last resort"" for such infections. Enterobacteriaceae are common commensals and infectious agents. Experts fear CRE as the new ""superbug"". The bacteria can kill up to half of patients who get bloodstream infections. Tom Frieden, head of the Centers for Disease Control has referred to CRE as ""nightmare bacteria"".
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