Highly specific radioimmunoassay for human insulin
... insulin. Indeed, immune exclusion of all insulin precursors by two MoAbs directed against the junction between A chain and C-peptide and the junction between B chain and C-peptide, respectively, leaves insulin as the sole reactant with the MoAb directed against the B chain. Effects of known amount o ...
... insulin. Indeed, immune exclusion of all insulin precursors by two MoAbs directed against the junction between A chain and C-peptide and the junction between B chain and C-peptide, respectively, leaves insulin as the sole reactant with the MoAb directed against the B chain. Effects of known amount o ...
Autonomic regulation of islet hormone secretion
... the perfused canine pancreas, ganglionic transmission could be more complex than simply involving nicotinic mechanisms. Possibly several other transmission pathways are also involved [16], but this has not been explored in great detail. The postganglionic nerve fibres innervating the islets release ...
... the perfused canine pancreas, ganglionic transmission could be more complex than simply involving nicotinic mechanisms. Possibly several other transmission pathways are also involved [16], but this has not been explored in great detail. The postganglionic nerve fibres innervating the islets release ...
Clinical and Investigative Endocrinology and Diabetes
... evaluated for worsening fatigue and was diagnosed with primary hypothyroidism and started on levothyroxine. He also had weight loss, diarrhea, abdominal pain, and tanned skin, so underwent evaluation for adrenal insufficiency. An ACTH stimulation test showed an elevated baseline ACTH level of 92 pg/ ...
... evaluated for worsening fatigue and was diagnosed with primary hypothyroidism and started on levothyroxine. He also had weight loss, diarrhea, abdominal pain, and tanned skin, so underwent evaluation for adrenal insufficiency. An ACTH stimulation test showed an elevated baseline ACTH level of 92 pg/ ...
Table of Contents - American Association of Clinical Endocrinologists
... in PG. Maternal mortality in undiagnosed patients is reported 17-56% and fetal mortality 26-58%. For tumor localization during PG, MRI is known to be safe. For the mode of delivery, cesarean section is preferred as it allows for greater control. With close monitoring and adequate alpha- adrenergic b ...
... in PG. Maternal mortality in undiagnosed patients is reported 17-56% and fetal mortality 26-58%. For tumor localization during PG, MRI is known to be safe. For the mode of delivery, cesarean section is preferred as it allows for greater control. With close monitoring and adequate alpha- adrenergic b ...
Title Slide
... • Diabetes Insipidus (DI) is a disorder in which there is an abnormal increase in urine output, fluid intake and often thirst (polyuria-polydipsia-syndrome). • Urine output is increased because it is not concentrated normally -> the urine is not yellow but pale, colorless or watery. • Diabetes Insip ...
... • Diabetes Insipidus (DI) is a disorder in which there is an abnormal increase in urine output, fluid intake and often thirst (polyuria-polydipsia-syndrome). • Urine output is increased because it is not concentrated normally -> the urine is not yellow but pale, colorless or watery. • Diabetes Insip ...
Test Selection and Interpretation The Quest Diagnostics Manual
... assays for most of the endocrine systems hormones, important metabolites and carrier proteins, free hormones, many hormone receptors, endocrine system autoantibodies, relevant chromosomal abnormalities, and selected genetic mutations. Our commitment to state of the art diagnostics and our dedication ...
... assays for most of the endocrine systems hormones, important metabolites and carrier proteins, free hormones, many hormone receptors, endocrine system autoantibodies, relevant chromosomal abnormalities, and selected genetic mutations. Our commitment to state of the art diagnostics and our dedication ...
abstracts - American Association of Clinical Endocrinologists
... during the development of the primitive foregut from which the bronchi & lungs develop. It results from aberrant budding from the ventral diverticulum, pinching off lung epithelium from primitive ventral foregut with aberrant migration into abdomen before fusion of diaphragm. Subdiagphramgmatic & me ...
... during the development of the primitive foregut from which the bronchi & lungs develop. It results from aberrant budding from the ventral diverticulum, pinching off lung epithelium from primitive ventral foregut with aberrant migration into abdomen before fusion of diaphragm. Subdiagphramgmatic & me ...
endocrine studies in stroke patients
... nervous system . Every horm one can act on the central nervous system , and the secretion of virtually every horm one is regulated directly or indirectly by the brain (1). In addition, m any horm ones are p roduced locally in the brain. Brain lesions m ay thus influence endocrine function profoundly ...
... nervous system . Every horm one can act on the central nervous system , and the secretion of virtually every horm one is regulated directly or indirectly by the brain (1). In addition, m any horm ones are p roduced locally in the brain. Brain lesions m ay thus influence endocrine function profoundly ...
The Discovery of Insulin - Albert Einstein College of Medicine
... 19 dogs, 14 of which had died, mostly from causes unrelated to the planned experiments (Bliss, 1982). At the end of the month, the pair prepared their first extract of the hypothetical internal secretion from degenerated pancreas that had been ground up and filtered. The filtrate did not cause a dec ...
... 19 dogs, 14 of which had died, mostly from causes unrelated to the planned experiments (Bliss, 1982). At the end of the month, the pair prepared their first extract of the hypothetical internal secretion from degenerated pancreas that had been ground up and filtered. The filtrate did not cause a dec ...
AFES 2015 Abstract Book V4 Final (English - pdf
... information, for any errors, omissions or inaccuracies, or for any consequences arising therefrom. With respect to any drugs mentioned, the reader is advised to refer to the appropriate medical literature and the product information currently provided by the manufacturer to verify appropriate dosage ...
... information, for any errors, omissions or inaccuracies, or for any consequences arising therefrom. With respect to any drugs mentioned, the reader is advised to refer to the appropriate medical literature and the product information currently provided by the manufacturer to verify appropriate dosage ...
Document
... information, for any errors, omissions or inaccuracies, or for any consequences arising therefrom. With respect to any drugs mentioned, the reader is advised to refer to the appropriate medical literature and the product information currently provided by the manufacturer to verify appropriate dosage ...
... information, for any errors, omissions or inaccuracies, or for any consequences arising therefrom. With respect to any drugs mentioned, the reader is advised to refer to the appropriate medical literature and the product information currently provided by the manufacturer to verify appropriate dosage ...
Renal Gluconeogenesis
... been either hepatectomized or hepatectomized and nephrectomized. In the former group, there was dilution of the plasma glucose 14C specific activity as the animals became hypoglycemic, indicating the release of unlabeled (i.e., endogenously produced) glucose into the circulation from some source oth ...
... been either hepatectomized or hepatectomized and nephrectomized. In the former group, there was dilution of the plasma glucose 14C specific activity as the animals became hypoglycemic, indicating the release of unlabeled (i.e., endogenously produced) glucose into the circulation from some source oth ...
recombiant drug
... secretion involved in digestion. Since then researchers have been trying to understand the role of these cells. In 1889, Oscar Minkowski and Joseph von Mering found that if they removed the pancreas from dogs, the animals would develop diabetes. This meant that this gland and the islets of Langerhan ...
... secretion involved in digestion. Since then researchers have been trying to understand the role of these cells. In 1889, Oscar Minkowski and Joseph von Mering found that if they removed the pancreas from dogs, the animals would develop diabetes. This meant that this gland and the islets of Langerhan ...
endocrinology and diabetes in schemes and images
... diagnostic and treatment algorithms, clinical guidelines and numerous original illustrations and digital images from both patients and diagnostic tests (echo, CT, MRI, nuclear medicine imaging). Most chapters have been reviewed by several members of the Spanish Society of Endocrinology or other scie ...
... diagnostic and treatment algorithms, clinical guidelines and numerous original illustrations and digital images from both patients and diagnostic tests (echo, CT, MRI, nuclear medicine imaging). Most chapters have been reviewed by several members of the Spanish Society of Endocrinology or other scie ...
effect of metformin on thyroid stimulating hormone in euthyroid type
... ABSTRACT: BACKGROUND AND RATIONALE: Metformin use is reported to be associated with reduction in serum thyroid stimulating hormone (TSH) levels. However, recent reports suggest that the effect of metformin on TSH is seen only in those who have hypothyroidism and not in those who are euthyroid. OBJEC ...
... ABSTRACT: BACKGROUND AND RATIONALE: Metformin use is reported to be associated with reduction in serum thyroid stimulating hormone (TSH) levels. However, recent reports suggest that the effect of metformin on TSH is seen only in those who have hypothyroidism and not in those who are euthyroid. OBJEC ...
Glucose Meter - Fundamentals and Design
... the liver cells, insulin instigates the conversion of glucose into glycogen and fat. In the fat cells of the adipose tissue, insulin also promotes the conversion of glucose into more fat and the uptake of glucose. 2. The pancreas will continue to release insulin and liver and fat cells continue to u ...
... the liver cells, insulin instigates the conversion of glucose into glycogen and fat. In the fat cells of the adipose tissue, insulin also promotes the conversion of glucose into more fat and the uptake of glucose. 2. The pancreas will continue to release insulin and liver and fat cells continue to u ...
The human brain produces fructose from glucose
... and in humans, acute ingestion of fructose or glucose causes different patterns of cerebral blood flow changes in brain regions that influence eating behavior (3, 4). Because glucose enters the brain via passage across the blood-brain barrier (BBB) (5, 6), it is generally assumed that the CNS effect ...
... and in humans, acute ingestion of fructose or glucose causes different patterns of cerebral blood flow changes in brain regions that influence eating behavior (3, 4). Because glucose enters the brain via passage across the blood-brain barrier (BBB) (5, 6), it is generally assumed that the CNS effect ...
Insulin - Diabetes Care - American Diabetes Association
... any unexplained increase in blood glucose to possible reductions in insulin potency. If uncertain about the potency of a vial of insulin, the individual should replace the vial in question with another of the same type. Mixing insulin Administration of mixtures of rapid- or short- and intermediate- ...
... any unexplained increase in blood glucose to possible reductions in insulin potency. If uncertain about the potency of a vial of insulin, the individual should replace the vial in question with another of the same type. Mixing insulin Administration of mixtures of rapid- or short- and intermediate- ...
Downloaded - Journal of Clinical Investigation
... fate for the glucose that is taken up by the liver (1) and defects in hepatic glycogen synthesis contribute to postprandial hyperglycemia of patients with poorly controlled insulin-dependent diabetes mellitus (IDDM)1 (2). Both insulin deficiency and relative hyperglucagonemia may lead to these abnor ...
... fate for the glucose that is taken up by the liver (1) and defects in hepatic glycogen synthesis contribute to postprandial hyperglycemia of patients with poorly controlled insulin-dependent diabetes mellitus (IDDM)1 (2). Both insulin deficiency and relative hyperglucagonemia may lead to these abnor ...
Chapter 20 outline
... Associated with a complete lack of insulin secretion, increased glucagon secretion, rapid onset of disease, ketosis, and severe symptoms Without insulin, type I DM is fatal Must be treated with injections of insulin cont’d… Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights res ...
... Associated with a complete lack of insulin secretion, increased glucagon secretion, rapid onset of disease, ketosis, and severe symptoms Without insulin, type I DM is fatal Must be treated with injections of insulin cont’d… Copyright © 2011, 2007 Mosby, Inc., an affiliate of Elsevier. All rights res ...
PDF - EnM :: Endocrinology and Metabolism
... Methods: A total of 154 patients (57 hyperthyroid patients, 61 euthyroid patients, and 36 hypothyroid patients; mean age, 47.9 years) were enrolled. Serum leptin, ghrelin, and insulin levels were measured and insulin resistance was calculated using the formula of the homeostasis model assessment of ...
... Methods: A total of 154 patients (57 hyperthyroid patients, 61 euthyroid patients, and 36 hypothyroid patients; mean age, 47.9 years) were enrolled. Serum leptin, ghrelin, and insulin levels were measured and insulin resistance was calculated using the formula of the homeostasis model assessment of ...
Hyperinsulinemic Hypoglycemia After Gastric
... study, we obtained pancreata collected at autopsy from the same institution. Pancreatic cancer is known to disturb islet function (19) and might also be expected to disturb islet morphology, given the markedly decreased food intake typically present in pancreatic cancer. Autopsy pancreas is prone to ...
... study, we obtained pancreata collected at autopsy from the same institution. Pancreatic cancer is known to disturb islet function (19) and might also be expected to disturb islet morphology, given the markedly decreased food intake typically present in pancreatic cancer. Autopsy pancreas is prone to ...
Effects of physiological hyperinsulinemia on systemic, renal, and
... Much of the glucose release by the liver is the result of glycogenolysis, a process that appears to be more sensitive to insulin than gluconeogenesis (6), whereas glucose release by the kidney is almost exclusively due to gluconeogenesis (46). Acidosis stimulates renal gluconeogenesis while suppress ...
... Much of the glucose release by the liver is the result of glycogenolysis, a process that appears to be more sensitive to insulin than gluconeogenesis (6), whereas glucose release by the kidney is almost exclusively due to gluconeogenesis (46). Acidosis stimulates renal gluconeogenesis while suppress ...
Supplementation by thylakoids to a high carbohydrate meal
... by the most energydense nutrient of fat also generates potent satiety signals via cholecystokinin (CCK), it is not able to inhibit energy intake fast enough to prevent overconsumption (Holt, Miller, Petocz, & Farmakalidis, 1995). In Sweden, intake of carbohydrates and proteins increased during the l ...
... by the most energydense nutrient of fat also generates potent satiety signals via cholecystokinin (CCK), it is not able to inhibit energy intake fast enough to prevent overconsumption (Holt, Miller, Petocz, & Farmakalidis, 1995). In Sweden, intake of carbohydrates and proteins increased during the l ...
Beta-cell function and mass in type 2 diabetes
... reduction of BCM and the ability to follow this parameter over time would greatly improve our understanding of disease progression and allow evaluation of pharmacological methods to increase BCM. BCM cannot, at present, be measured in vivo in humans. We therefore set out to further validate data fro ...
... reduction of BCM and the ability to follow this parameter over time would greatly improve our understanding of disease progression and allow evaluation of pharmacological methods to increase BCM. BCM cannot, at present, be measured in vivo in humans. We therefore set out to further validate data fro ...