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platelet function testing-guided antiplatelet therapy
platelet function testing-guided antiplatelet therapy

... Cardiovascular diseases are the leading cause of death in the Western world. Several factors have led to the increase in vascular disorders, including the aging population, unhealthy lifestyles, increasing rates of diabetes and raised lipids, and further risk factors resulting in inflammation and cal ...
Stingray Barb Injury: A Cause of Late Coronary Occlusion and
Stingray Barb Injury: A Cause of Late Coronary Occlusion and

... The stingray barb is a remarkable feat of bioengineering. It is stiletto thin and sharp, and its edges are lined with backward-pointing, harpoonlike, retroserrations (Fig 4A) that are anchored in soft tissue, preventing its easy removal without severe tissue damage (Fig 4B). The patient was free of ...
Intra-aortic Balloon Counterpulsation: Indications and pitfalls
Intra-aortic Balloon Counterpulsation: Indications and pitfalls

... American Heart Association as well as the European Society of Cardiology for IABP  utilization in STEMI (ST‐Segment Elevation Myocardial Infarction), there is a  growing body of literature that shows no efficacy benefit.   The lack of active cardiac  support, and the need to have some level of resid ...
1 MedCHAMPS Technical Appendix Supplementary Online Content
1 MedCHAMPS Technical Appendix Supplementary Online Content

... The data sources used are shown in eTable 1. Mortality data was obtained from the ministry of health-health information centre for the years 1997 up to 2009. Mortality data for the year 1998 was not complete. The numbers used for the year 1998 were the average number for the previous (1997) and next ...
PEGASUS-TIMI 54: Ticagrelor versus Placebo in Patients with Prior MI
PEGASUS-TIMI 54: Ticagrelor versus Placebo in Patients with Prior MI

... Ticagrelor was used in <1% of patients prior to randomization (~94% were on clopidogrel).    Patients at risk of bradycardia were excluded from the trial. Ticagrelor has been shown to cause more ventricular pauses  ...
Relation of atherosclerosis risk factors with the number of involved
Relation of atherosclerosis risk factors with the number of involved

... some social, environmental and behavioural factors that may increase the risk of atherosclerosis (12). Framingham studies showed that coronary artery disease does not occur completely random and highrisk individuals can be detected based on number of some risk factors before the onset of clinical sy ...
Print this article - Publicatii USAMV Cluj
Print this article - Publicatii USAMV Cluj

... The terminal part of the right coronary artery is flexuous having an “S” – shape like, and continues downwards with the right interventricular artery (the real terminal branch) and with a secondary branch–the right circumflex artery (Fig.8). The right interventricular artery passes downwards on the ...
Establishment of a Two Coronary Artery System in Anomalous
Establishment of a Two Coronary Artery System in Anomalous

... regurgitation with fibrotic papillary muscle. Although this child survived after surgery but left ventricular function was only 20% at 3 months follow up. We suspect an irreversible heart failure on this patient. However Fratz et al [7] studying cardiac magnetic resonance including LV function analy ...
Can Lifestyle Changes Reverse Coronary Heart
Can Lifestyle Changes Reverse Coronary Heart

... (18·5)% in the control group. When only lesions greater than 50% stenosed were analysed, the ...
slides
slides

... • Lumen stabilization and scaffold disappearance are the key ingredients for a durable SFA therapy. • Combining endovascular legacy with deep coronary BVS experience creates a specialized platform to address long term SFA needs BVS for the peripheral arteries in an investigational device outside the ...
Main text
Main text

... dysfunction of cardiac autonomic nerve and more worse diseases was shown between the number of coronary artery diseased and HRV, meanwhile, other clinical practice have similar reports. Takei et al 18, found that among ACS patients, all indicators of HRV in multivessels diseased group were lower si ...
Post-PCI Atrial Fibrillation: Possible Clinical and Prognostic
Post-PCI Atrial Fibrillation: Possible Clinical and Prognostic

... significantly longer intra-atrial and inter-atrial conduction time of sinus impulses [8–10]. This has been confirmed by the finding of P-wave prolongation on 12-lead surface ECG and signal-averaged ECG recordings [11–13]. The importance of P-wave dispersion in predicting recurrence of AF in patients ...
3 - JACC
3 - JACC

... statistically significant effect on the placebo-adjusted geometric mean percent changes from baseline in TnI at 16 h post-PCI (⫺3.4%, p ⫽ 0.81), in TnI at 24 h post-PCI (⫺1.4%, p ⫽ 0.93), in peak TnI (⫺1.5%, p ⫽ 0.92), in the AUC over 24 h for TnI (⫺27.2%, p ⫽ 0.19), and in CK-MB at 16 h (⫺7.0%, p ⫽ ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Although revascularization procedures by percutaneous intervention or bypass surgery are largely used in the treatment of ischemic heart disease, there remains a relatively large number of patients with refractory angina. These “no options” patients frequently have diffuse coronary disease without a ...
Drugs used in the treatment of Angina Pectoris
Drugs used in the treatment of Angina Pectoris

... - clonidine lowers heart rate and cardiac output more than does methyldopa. - Reduction in arterial blood pressure by clonidine and methyldopa is accompanied by decreased renal vascular resistance and maintenance of renal blood flow. - Adverse effects: Dry mouth and sedation , should not be given to ...
Isolated congenital absence of coronary sinus - Heart
Isolated congenital absence of coronary sinus - Heart

... increase in intensity of the murmur after exercise and glyceryl trinitrate was, we believe, caused by increased venous return across the stenosis consequent upon an increase in myocardial blood flow. The further decrease in systemic oxygen saturation on exercise reflects both increased myocardial ox ...
Print - Circulation
Print - Circulation

... vessels. At the completion of the second anastomosis, the aortic clamp was removed and the heart resumed its beats spontaneously. Excessive bleeding from the anastonmosis compelled us to reclamp the aorta and try to control the bleeding. We also elected to perform the pulmonary artery anastomosis at ...
RENAL ARTERY STENOSIS
RENAL ARTERY STENOSIS

... There were 2 technical failures and 12 patients should not have been randomized because they had less than 50% stenosis on angiography and thus were not stented. Yet all 64 patients were analyzed(by intention to treat) in the stent group • Like DRASTIC , this trial was underpowered • High complicati ...
A Clinical Randomized Trial to Evaluate the Safety
A Clinical Randomized Trial to Evaluate the Safety

... the feasibility of prophylactic revascularization in high-risk patients scheduled for major vascular surgery, and to obtain initial efficacy and safety estimates needed for the design of an adequately powered randomized controlled clinical trial. We aimed for the enrollment of 100 patients, 50 in ea ...
Prognostication of long-term outcomes for patients with ischemic
Prognostication of long-term outcomes for patients with ischemic

... were evaluated. Risk factors for CHD were evaluated during this study. Arterial hypertension was diagnosed with a history of BP ≥140/90 mm Hg or if antihypertensive medications were prescribed for a patient. Dyslipidemia was diagnosed as an increase in low-density lipoprotein cholesterol (LDL-Ch) le ...
Acute Care Case Study Paper
Acute Care Case Study Paper

... one that is high in saturated fat and sodium and low in fiber, usually resulting in obesity and abnormal lipid profiles (elevated serum LDL cholesterol, total cholesterol and triglycerides paired with low serum HDL cholesterol). Given this dietary-dyslipidemic relationship, the greater the concentra ...
Postoperative bleeding in CABG Patients: New Study in Southwest
Postoperative bleeding in CABG Patients: New Study in Southwest

... (12). In addition to the economic burden, administration of blood products in cardiac surgery have important clinical outcomes, that increased hospital mortality, renal dysfunction, perioperative infections, sepsis, and permanent impairment of quality of life and pulmonary dysfunction and prolonged ...
Percutaneous Coronary Intervention (PCI)
Percutaneous Coronary Intervention (PCI)

... Plan to have a responsible adult take you home the day following your PCI. For their own safety, children under 16 may not visit in the testing area. They may stay in the waiting room with a responsible adult. You will be assigned a bed for both your pre- and post-PCI care. After you change into a h ...
The REGULATE-PCI Randomized Clinical Trial
The REGULATE-PCI Randomized Clinical Trial

... phase 3 trial to test the hypothesis that near complete FIXa inhibition with Pegnivacogin during PCI would provide a greater reduction in ischemic events than bivalirudin without increased bleeding as a result of anticoagulant reversal with Anivamersen. ...
this PDF file - Pakistan Heart Journal
this PDF file - Pakistan Heart Journal

... frequency cannot be deemed to be the prevalence of WMA in the general population. Therefore, this is a major limitation in our study. However, this does gives us an idea of the percentage of WMA cases in patients having some sort of Cardiac symptoms (for which they had been come or were referred for ...
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Drug-eluting stent



A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.
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