Synthesis of Heme
... Hepcidin secretion increases when iron levels are high or in response to cytokines produced at sites of inflammation. Degradation of ferroportin leads to decreased absorption of dietary iron and decreased serum iron. Hepcidin is considered an antimicrobial peptide because by lowering serum iron it w ...
... Hepcidin secretion increases when iron levels are high or in response to cytokines produced at sites of inflammation. Degradation of ferroportin leads to decreased absorption of dietary iron and decreased serum iron. Hepcidin is considered an antimicrobial peptide because by lowering serum iron it w ...
Li_uta_2502D_12817
... Wei Li, PhD The University of Texas at Arlington, 2014 Supervising Professor: Brad Pierce Cysteine dioxygenase (CDO) is an non-heme mononuclear iron enzymes that catalyzes the O2-dependent oxidation of L-cysteine (Cys) to produce cysteine sulfinic acid (CSA). CDO controls cysteine levels in cells an ...
... Wei Li, PhD The University of Texas at Arlington, 2014 Supervising Professor: Brad Pierce Cysteine dioxygenase (CDO) is an non-heme mononuclear iron enzymes that catalyzes the O2-dependent oxidation of L-cysteine (Cys) to produce cysteine sulfinic acid (CSA). CDO controls cysteine levels in cells an ...
Letters in Applied Microbiology
... As strains from P. fluorescens and related species colonize the rhizosphere aggressively, competition with root pathogens for nutrients and root surface colonization has been proposed as an important trait for biological control (Fig. 2; Table 1), although in recent years its significance has been d ...
... As strains from P. fluorescens and related species colonize the rhizosphere aggressively, competition with root pathogens for nutrients and root surface colonization has been proposed as an important trait for biological control (Fig. 2; Table 1), although in recent years its significance has been d ...
The Utilization of Magnesium by Certain Gram
... Although the magnesium requirements for maximal growth in simple chemically defined media are some ten times greater for Gram-positive bacteria than for Gramnegative bacteria (Webb, 1949a) the magnesium contents of these organisms do not differ greatly (Webb, 19498; Rouf, 1964), and it is probable t ...
... Although the magnesium requirements for maximal growth in simple chemically defined media are some ten times greater for Gram-positive bacteria than for Gramnegative bacteria (Webb, 1949a) the magnesium contents of these organisms do not differ greatly (Webb, 19498; Rouf, 1964), and it is probable t ...
6 - Beta-Sheet.org
... dependent upon a cyclic photophosphorylating electron transport chain or alternatively in the dark in the presence of oxygen and reduced organic substrates, utilizing an oxidative electron transport chain for the production of ATP. The organism in either case produces large amounts of cytochrome CP, ...
... dependent upon a cyclic photophosphorylating electron transport chain or alternatively in the dark in the presence of oxygen and reduced organic substrates, utilizing an oxidative electron transport chain for the production of ATP. The organism in either case produces large amounts of cytochrome CP, ...
Synthesis and Structure of Biomimetic Porphyrins
... which the iron has been irreversibly oxidized to the ferric form (Scheme I)8-11. ...
... which the iron has been irreversibly oxidized to the ferric form (Scheme I)8-11. ...
PATHOPHYSIOLOGY OF RED BLOOD CELLS Zsófia Mezei, MD
... Apoferritin synthetised in mucosal cells takes up iron. From ferritin iron gets to the carrier plasma protein transferrin. Transferrin is a beta-globulin synthethised by the liver. Iron distribution: Only small amount of ferritin is found in serum. There is a close relation between Se ferritin and i ...
... Apoferritin synthetised in mucosal cells takes up iron. From ferritin iron gets to the carrier plasma protein transferrin. Transferrin is a beta-globulin synthethised by the liver. Iron distribution: Only small amount of ferritin is found in serum. There is a close relation between Se ferritin and i ...
Correlation between the respiration-driven Na+ pump
... halophiles examined are resistant to hypotonic lysis, do not have any respiration-driven Na+ pump, and exhibit no requirement for Na+ for AIB uptake. Since these Gram-positive halophiles have none of the properties characteristic of marine bacteria, they are unlikely to originate from marine environ ...
... halophiles examined are resistant to hypotonic lysis, do not have any respiration-driven Na+ pump, and exhibit no requirement for Na+ for AIB uptake. Since these Gram-positive halophiles have none of the properties characteristic of marine bacteria, they are unlikely to originate from marine environ ...
Iron mediated methylthiolation of tRNA as a regulator of operon
... 3.5 ( Whatman 3MM paper (8)). Ap,Cp,Gp,Up and s Up (PL Biochemicals Inc.,USA) were used as markers. Radioactive compounds were obtained from The Radiochemical Centre, Amershara. Polypeptide synthesis in vitro E. ooli was grown in trypticase soy broth with or without ovotransferrin from an inoculum o ...
... 3.5 ( Whatman 3MM paper (8)). Ap,Cp,Gp,Up and s Up (PL Biochemicals Inc.,USA) were used as markers. Radioactive compounds were obtained from The Radiochemical Centre, Amershara. Polypeptide synthesis in vitro E. ooli was grown in trypticase soy broth with or without ovotransferrin from an inoculum o ...
Mechanisms that promote bacterial fitness in fungal
... As outlined in Fig. 1, the mycorrhizosphere constitutes a specific microhabitat in soil that offers specific niches to adapted microbial soil inhabitants. It encompasses the mutual effects of plant roots and their associated fungal hyphae, resulting in a locally defined microhabitat shaped by the tw ...
... As outlined in Fig. 1, the mycorrhizosphere constitutes a specific microhabitat in soil that offers specific niches to adapted microbial soil inhabitants. It encompasses the mutual effects of plant roots and their associated fungal hyphae, resulting in a locally defined microhabitat shaped by the tw ...
PORPHYRINS
... • Turnover of Hemeproteins (Hemoglobin, etc) is coordinated with synthesis and degradation of porphyrins • Bound iron is recycled ...
... • Turnover of Hemeproteins (Hemoglobin, etc) is coordinated with synthesis and degradation of porphyrins • Bound iron is recycled ...
University of Groningen The ecological success of
... (416 million years ago), land was increasingly colonized by plants (Redecker et al., 2000; Gensel, 2008). Given the primary production by plants (del Giorgio, 1998) and the known release of carbonaceous compounds by their roots, members of the soil microbiota would have evolved at an early stage to ...
... (416 million years ago), land was increasingly colonized by plants (Redecker et al., 2000; Gensel, 2008). Given the primary production by plants (del Giorgio, 1998) and the known release of carbonaceous compounds by their roots, members of the soil microbiota would have evolved at an early stage to ...
Isolation of Rat Transferrin Using CNBr-Activated
... Introduction For studies on the rate of renewal of components in biological systems we have chosen äs a model the iron transporting system (1). For this reason we require the iron containing proteins transferrin and ferritin in a homogeneous state. Transferrin is the most important transport protein ...
... Introduction For studies on the rate of renewal of components in biological systems we have chosen äs a model the iron transporting system (1). For this reason we require the iron containing proteins transferrin and ferritin in a homogeneous state. Transferrin is the most important transport protein ...
Sam P. de Visser,* Jan-Uwe Rohde,* Yong
... bond activation for a variety of purposes, including biosynthetic functions, DNA repair, and cellular oxygen sensing. Many of these enzymes, including several ˛-ketoglutarate- (˛KG) and pterin-dependent oxygenases for which such a high-valent Fe intermediate has been trapped in recent years, contain ...
... bond activation for a variety of purposes, including biosynthetic functions, DNA repair, and cellular oxygen sensing. Many of these enzymes, including several ˛-ketoglutarate- (˛KG) and pterin-dependent oxygenases for which such a high-valent Fe intermediate has been trapped in recent years, contain ...
A tribute to sulfur - Wiley Online Library
... was found that the active site Cys residue is located in the middle of a highly flexible loop of 12 amino acids, which may be able to adapt to varied geometries in acceptor proteins. The 3D structure of C-DES from Synechocystis has now also become available [52]. Contrary to the NifS type Cys desulf ...
... was found that the active site Cys residue is located in the middle of a highly flexible loop of 12 amino acids, which may be able to adapt to varied geometries in acceptor proteins. The 3D structure of C-DES from Synechocystis has now also become available [52]. Contrary to the NifS type Cys desulf ...
Constitutive expression of RyhB regulates the heme biosynthesis
... In this study, we found that the constitutive overexpression of natural small RNA RyhB influenced the transcription of iron-containing enzymes and drove the metabolic flux to ALA production. Interestingly, overexpression of ryhB down-regulated the transcription of hemB and hemH. The presence of poss ...
... In this study, we found that the constitutive overexpression of natural small RNA RyhB influenced the transcription of iron-containing enzymes and drove the metabolic flux to ALA production. Interestingly, overexpression of ryhB down-regulated the transcription of hemB and hemH. The presence of poss ...
Multiple long-term, experimentally
... iron is to secrete and reabsorb small molecules called siderophores that chelate extracellular Fe (III), as well as the transporters to utilize them. E. coli also has the ability to take up Fe (II), and a transport system to directly capture Fe (III) from host proteins like transferrin or lactoferri ...
... iron is to secrete and reabsorb small molecules called siderophores that chelate extracellular Fe (III), as well as the transporters to utilize them. E. coli also has the ability to take up Fe (II), and a transport system to directly capture Fe (III) from host proteins like transferrin or lactoferri ...
Iron-sulfur proteins and the role of iron in the gene expression of
... fundamental importance. This metal is crucial for the survival and replication of almost all living organisms because of its unparalleled versatility as a biological catalyst. Its unique features originate from the extreme flexibility of the Fe2+/Fe3+ redox potential, which is determined by the char ...
... fundamental importance. This metal is crucial for the survival and replication of almost all living organisms because of its unparalleled versatility as a biological catalyst. Its unique features originate from the extreme flexibility of the Fe2+/Fe3+ redox potential, which is determined by the char ...
"Bacteria" pdf file
... needed before starting this kind of production. American scientists have thought of taking pieces of DNA which are responsible for the conversion cycle of glucose into energy storage molecules from different organisms and then combine this genetic material and insert it into a microorganism to give ...
... needed before starting this kind of production. American scientists have thought of taking pieces of DNA which are responsible for the conversion cycle of glucose into energy storage molecules from different organisms and then combine this genetic material and insert it into a microorganism to give ...
physiological limitations on phytoplankton productivity in the ocean
... symptoms of an environmental constraint on phytoplankton growth rates. The aim of diagnostics is to interrogate, without experimentally manipulating, natural phytoplankton. If, for example, the growth rate of cells is limited by temperature or the availability of nitrogen, iron, or light, then signa ...
... symptoms of an environmental constraint on phytoplankton growth rates. The aim of diagnostics is to interrogate, without experimentally manipulating, natural phytoplankton. If, for example, the growth rate of cells is limited by temperature or the availability of nitrogen, iron, or light, then signa ...
Bioorganometallic Chemistry - Chemistry and Biochemistry
... of hydrogenase active sites and those of other complex iron-sulfur enzymes and iron-sulfur mineral structures and reactivity have also been gaining interest. Given that complex iron-sulfur enzymes are involved with reactions such as reversible hydrogen oxidation, nitrogen fixation, and reversible car ...
... of hydrogenase active sites and those of other complex iron-sulfur enzymes and iron-sulfur mineral structures and reactivity have also been gaining interest. Given that complex iron-sulfur enzymes are involved with reactions such as reversible hydrogen oxidation, nitrogen fixation, and reversible car ...
Reaction Mechanisms of Mononuclear Non
... PAH has been cloned from both prokaryotes and eukaryotes, whereas TH and TPH seem to be strictly eukaryotic enzymes. Interestingly, to date, there are many amino acid sequences coding eukaryotic PAH that have been deposited on NCBI, whereas there are only about seven prokaryotic sequences. Although ...
... PAH has been cloned from both prokaryotes and eukaryotes, whereas TH and TPH seem to be strictly eukaryotic enzymes. Interestingly, to date, there are many amino acid sequences coding eukaryotic PAH that have been deposited on NCBI, whereas there are only about seven prokaryotic sequences. Although ...
The influence of iron deficiency on the functioning of skeletal
... genes in skeletal muscle, see Polonifi et al.41 and Sekyere et al.42 ) As mentioned before, little has as yet been unravelled regarding the mechanisms that control local iron regulation in skeletal muscle. Since the expression of two main regulatory peptides, namely HAMP and HJV, has been confirmed ...
... genes in skeletal muscle, see Polonifi et al.41 and Sekyere et al.42 ) As mentioned before, little has as yet been unravelled regarding the mechanisms that control local iron regulation in skeletal muscle. Since the expression of two main regulatory peptides, namely HAMP and HJV, has been confirmed ...
Transport and Storage of Metal Ions in Biology
... an environment ®lled with metal ion chelators such as soluble proteins, peptides (e.g., glutathione), and organic metabolites (e.g., citrate). These molecules may impede the ability of metalloproteins to acquire their metal cofactor by acting as competitive chelators. In the case of Cu, speci®c solu ...
... an environment ®lled with metal ion chelators such as soluble proteins, peptides (e.g., glutathione), and organic metabolites (e.g., citrate). These molecules may impede the ability of metalloproteins to acquire their metal cofactor by acting as competitive chelators. In the case of Cu, speci®c solu ...
Siderophore
Siderophores (Greek: ""iron carrier"") are small, high-affinity iron chelating compounds secreted by microorganisms such as bacteria, fungi and grasses. Siderophores are amongst the strongest soluble Fe3+ binding agents known.