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Glossary 29Sept2012_Genetics
Glossary 29Sept2012_Genetics

... gene. The order of a DNA string's base pairs determines which proteins are produced, and thus the function of a particular cell. Trait: The physical characteristics, like eye color or nose shape, which are determined by inherited genes. ...
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Analyzing Genomic Dose-Response Information to Inform Key

... arsenic-induced apoptosis (chemotherapy). E.g., apoptotic genes (e.g., JNK) may be activated at lower concentrations than in primary cells; in the ST486 B-lymphoma cell line, 80% apoptosis was observed at 5µM (Muscarella and Bloom 2002). Some genes are functionally inactive in cancerous cells. In hu ...
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... 9. Is the following sentence true or false? Barr bodies are found only in males. ________________________________________ 10. If you see a white cat with orange and black spots, is it most likely a male or a female? ______________________ Explain _____________________________________________________ ...
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Concept 9.2 The Cell Cycle Multiplies Cells

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... Q13:* To get entire genome of cell by broken up DNA at it ,then cleaved with restriction endonuclease, these DNA piece are spliced into plasmids or phages and cloned, then various selective techniques are used to isolate the desired DNA sequences. *it starts with cells in which the gene of interest ...
Cancer Doesn’t Happen Overnight
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Gene Section MTA3 (metastasis associated 1 family, member 3)

... Haemangiogenesis and lymphomagenesis A high expression level of MTA3 was found in germinal centre B lymphocytes, suggesting an involvement in B cell maturation by direct interaction with BCL6. BCL6 (B-cell lymphoma-6) is a transcriptional repressor that is co-expressed with MTA3 in the germinal cent ...
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Polycomb Group Proteins and Cancer

The Polycomb-group proteins (PcGs) are a family of proteins that use epigenetic mechanisms to maintain or repress expression of their target genes. They were originally discovered in Drosophila (fruit flies), though they've been shown to be conserved in many species due to their vital roles in embryonic development. These proteins' ability to alter gene expression has made them targets of investigation for research groups seeking to understand disease pathology and oncology.
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