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What unites these phenomena?
What unites these phenomena?

... • Imprinted gene function in mammals -- the level of gene expression is dependent on whether the gene copy came from mom or dad • Phenotypic plasticity associated with variations in the environment to which an organism is exposed • Adult neuronal plasticity and neurogenesis --changes in chromatin ma ...
Klinisches Fehler- und Risikomanagement
Klinisches Fehler- und Risikomanagement

... [12] Naumova OY et al.: Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents. Developmental Psychopathology, 24(1). 143-155 (2012) [13] McGowan PO et al.: Epigenetic regulation in the glucocorticoid receptor in human brai ...
Regulation and Expression of Aldehyde Dehydrogenase in Normal
Regulation and Expression of Aldehyde Dehydrogenase in Normal

... commonly associated with the progression of human cancers. Hypermethylation of CpG islands is the most well categorised epigenetic change to occur in tumours. Many CpG islands associated with transcription of a wide variety of genes become aberrantly methylated in tumours. Genes representing all the ...
Toward the Identification of Peripheral Epigenetic Biomarkersof
Toward the Identification of Peripheral Epigenetic Biomarkersof

... mediating the clinical manifestations and course of the disease. We have reported that two enzymes that belong to the dynamic DNA-methylation/demethylation networkDNMT (DNA-methyltransferase) and TET (5-hydroxycytosine translocator)-are abnormally increased in cortico-limbic structures of the SZ pos ...
Epigenetics: Biologic Targets, Biomarkers and Role in Disease
Epigenetics: Biologic Targets, Biomarkers and Role in Disease

... and appearance of tissues in each multicellular organism. Epigenetic regulation includes chromatin organization and modification of histone tails to provide a “code” for the expression or silencing of genes during differentiation. These states, unlike genetic alterations, are potentially reversible, ...
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Epigenetic clock

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