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Guidelines on Choice and Selection of Antipsychotics
Guidelines on Choice and Selection of Antipsychotics

... used to reduce symptoms in the acute psychotic phase of the illness and also as maintenance treatment to reduce the likelihood of psychotic relapses in stable patients. The National Institute of Health and Care Excellence (NICE) Clinical Guidelines 178 for Psychosis and Schizophrenia in Adults recom ...
Xanax (alprazolam)
Xanax (alprazolam)

... Xanax affects alertness and coordination, and patients should exercise caution when driving or performing other tasks requiring alertness while taking this medication. Seniors may be more adversely affected, because it may affect their coordination and reflexes and lead to falls and injury. Taking X ...
Eltroxin - Medsafe
Eltroxin - Medsafe

... to a new brand or formulation. There are approximately 70,000 patients taking Eltroxin in New Zealand. In July 2007, the manufacturer of Eltroxin tablets (GlaxoSmithKline) introduced a new formulation of the product and stopped making the formulation previously supplied in New Zealand. Although the ...
Update on lipid management. Commonly asked questions
Update on lipid management. Commonly asked questions

... authorisation (ezetimibe and its combinations) and by PBS criteria for Medicare reimbursement. The PBS criteria are based on cut-off levels for starting drug therapy, rather than absolute levels of CVD risk. On the basis of absolute risk, a case can be made to provide statins to all highrisk patient ...
alprolix - Biogen Canada
alprolix - Biogen Canada

... IX results can be affected by the type of aPTT reagent used. Measurement with a one-stage clotting assay utilizing a kaolin-based aPTT reagent will likely result in an underestimation of activity level. Monitor for the development of factor IX inhibitors. If bleeding is not controlled with ALPROLIX ...
Monitoring and management of steroid
Monitoring and management of steroid

... vision loss, in which case it is termed steroidinduced ocular hypertension. Patients with healthy optic nerves can tolerate higher IOPs and longer periods of ocular hypertension before their nerves develop sufficient damage to cause vision loss.3 If the IOP rise is high enough or sustained for long ...
Respiratory Pharmacology Week 6
Respiratory Pharmacology Week 6

... causes hepatitis C from spreading inside the body. It is not known if treatment that includes ribavirin and another medication cures hepatitis C infection, prevents liver damage that may be caused by hepatitis C, or prevents the spread of hepatitis C to other people. ...
Product Information: Rifaximin
Product Information: Rifaximin

... Due to the effects on the gut flora, the effectiveness of oral oestrogenic contraceptives could decrease after rifaximin administration. However, such interactions have not been commonly reported. It is however recommended to take additional contraceptive precautions, in particular if the oestrogen ...
Chapter 15 Antiepileptic Drugs
Chapter 15 Antiepileptic Drugs

... Bone marrow hypoplasia Gingival Hyperplasia(齿龈增生)occur to some degree in most patient. ...
Acute Angle Closure Glaucoma
Acute Angle Closure Glaucoma

... Management – Reassessment  Ophthalmic agents, miotic- (Pilocarpine) opening of the angle  Approx 1 hour after beginning treatment, administered every 15 ...
HIGHLIGHTS OF PRESCRIBING
HIGHLIGHTS OF PRESCRIBING

... Sumavel DosePro is contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Sumavel DosePro. Some of these reactions occurred in pat ...
ARVO 2015 Annual Meeting Abstracts 219 Epidemiology
ARVO 2015 Annual Meeting Abstracts 219 Epidemiology

... Nijmegen, Netherlands; 2Ophthalmology, Radboud University Medical Center, Nijmegen, Netherlands. Purpose: Diabetic Retinopathy (DRP) and Age-related Macular Degeneration are the most common visual threatening eye diseases in industrialized countries. Detection of these diseases at an early stage can ...
MIRAPEX Prescribing Information
MIRAPEX Prescribing Information

... MIRAPEX tablets were effective and well tolerated over a dosage range of 1.5 to 4.5 mg/day administered in equally divided doses three times per day with or without concomitant levodopa (approximately 800 mg/day). In a fixed-dose study in early Parkinson's disease patients, doses of 3 mg, 4.5 mg, an ...
Oral Therapies for Cancer - Oncology Nursing Society
Oral Therapies for Cancer - Oncology Nursing Society

... tacrolimus, ergot alkaloids, simvastatin. Avoid co‐administration or administer  cautiously.  Avoid grapefruit juice and grapefruit.  Is teratogenic and embryo‐fetal toxic. Women of childbearing potential should  be advised to avoid pregnancy. Women should not breastfeed while on  dasatinib. Can imp ...
Dabigatran - Developing Anaesthesia
Dabigatran - Developing Anaesthesia

... The NOACs as a group are potent anticoagulant agents and overdose with any amount could result in clinically significant bleeding. Classic coagulation tests correlate poorly with the anticoagulant effect of these agents and have a limited role in refining the risk assessment. There are no published ...
Intra-patient Dose Escalation
Intra-patient Dose Escalation

... • If analyzed properly, they can provide information about inter-patient variability in dose–response effects • The succession of dose levels is not necessarily determined completely by choices made before the onset of the trial ...
Second-generation cephalosporins
Second-generation cephalosporins

... • The second generation agents have inferior activity against penicillin-resistant S. pneumoniae compared to either the 3rd generation agents or ampicillin and therefore should not be used for treatment of meningitis or pneumonia. • In case where Gm -ve bacteria and anaerobes are involved such as in ...
Anti VEGF Agents in Retinal Disorders – Current Scenario
Anti VEGF Agents in Retinal Disorders – Current Scenario

... baseline was +8.7 letters at week 52 and +7.9 letters at week 96, with a mean of 16.5 injections over the two years   *  "A  X  /<  #  result was also good. Decreased frequency of treatment while retaining the safety       ! "   _ ...
Diuretics
Diuretics

... Distribution in extracellular space Elimination unchanged in kidney Variable elimination kinetics and therefore variable half-lives of elimination ranging from hours to days. ...
Initial dose per day (mg)
Initial dose per day (mg)

...  Moderate GI/low CV risk: should receive a COX-2 inhibitor alone or a conventional NSAID PLUS a PPI or misoprostol.  Moderate GI/high CV risk: should receive naproxen PLUS a PPI or misoprostol  Low GI/high CV risk: should receive naproxen PLUS a PPI or misoprostol  Low GI/low CV risk: can receiv ...
Chapter 40 - parangalan.com
Chapter 40 - parangalan.com

... hypertension and considered 2nd line treatment, because tends to change color of the iris Sympathomimetic Agents, (ex. Epinephrine) stimulate adrenergic receptors within the eye, initially may result in a reduction of aqueous humor production, prolonged therapy with these drugs may result in an incr ...
GPs guide to some topical eye medications
GPs guide to some topical eye medications

... Topical steroids are also used in selected infective conditions, including herpes zoster keratitis and after trauma including thermal, chemical or radiation injury, after weighing the risk against the benefit of reduction of inflammation. In these situations, specialist involvement is strongly advis ...
DIOVAN
DIOVAN

... Other adverse experiences with frequency below 1 % included: oedema; asthenia; insomnia; rash; decreased libido, vertigo. It is unknown whether these effects were causally related to valsartan therapy. Post-marketing data revealed very rare cases of angioedema, rash, pruritus, and other hypersensiti ...
The Itchy Eye: Diagnosis and Management of Ocular Pruritus
The Itchy Eye: Diagnosis and Management of Ocular Pruritus

... patients about proper hygiene. It may be helpful to change to daily-wear contact lenses. Once the exacerbation has­resolved, mast-cell stabilizers are sometimes used as maintenance ther­ apy. For those who remain intolerant, refractive surgery is an alternative. Meibomian gland dysfunction/ blephari ...
Prescribing Information
Prescribing Information

... Pregnancy Category C There are no adequate and well-controlled trials in pregnant women. In developmental toxicity studies in rats and rabbits, oral administration of sumatriptan to pregnant animals was associated with embryolethality, fetal abnormalities, and pup mortality. When administered by the ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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