Avian Medicine: Princilpes and Application
... Available as injectable solutions (50 mg/ml and 250 mg/ml) for IM or SC administration. Limited activity against gram-positive organisms. Should be used only in birds when absolutely necessary to treat gram-negative bacteria (Pseudomonas, Klebsiella spp.) that are resistant to other, less toxic anti ...
... Available as injectable solutions (50 mg/ml and 250 mg/ml) for IM or SC administration. Limited activity against gram-positive organisms. Should be used only in birds when absolutely necessary to treat gram-negative bacteria (Pseudomonas, Klebsiella spp.) that are resistant to other, less toxic anti ...
Extract from the Clinical Evaluation Report for Fentanyl citrate
... The ability to achieve a rapid analgesic effect is important in the management of pain for patients with cancer who, despite continuous background analgesia, often experience recurrent episodes of acute transitory pain otherwise known as breakthrough pain (BTP). Opioid analgesics are standard treatm ...
... The ability to achieve a rapid analgesic effect is important in the management of pain for patients with cancer who, despite continuous background analgesia, often experience recurrent episodes of acute transitory pain otherwise known as breakthrough pain (BTP). Opioid analgesics are standard treatm ...
DRUG NAME: Cytarabine
... Neurotoxicity (8-10%) typically occurs 3-8 days after initiating therapy.2,4,12,22 Cerebellar dysfunction is characterized by difficulty with speech, trouble standing or walking, and tremors. Cerebral dysfunction may be seen concomitantly and is characterized by somnolence, confusion, personality ch ...
... Neurotoxicity (8-10%) typically occurs 3-8 days after initiating therapy.2,4,12,22 Cerebellar dysfunction is characterized by difficulty with speech, trouble standing or walking, and tremors. Cerebral dysfunction may be seen concomitantly and is characterized by somnolence, confusion, personality ch ...
PRODUCT INFORMATION STOCRIN® (efavirenz) Tablets and Oral
... metabolites are essentially inactive against HIV-1. The in vitro studies suggest that CYP3A4 and CYP2B6 are the major isozymes responsible for efavirenz metabolism. In vitro studies have shown that efavirenz inhibited P450 isozymes 2C9, 2C19, and 3A4 with Ki values (8.517µM) in the range of observed ...
... metabolites are essentially inactive against HIV-1. The in vitro studies suggest that CYP3A4 and CYP2B6 are the major isozymes responsible for efavirenz metabolism. In vitro studies have shown that efavirenz inhibited P450 isozymes 2C9, 2C19, and 3A4 with Ki values (8.517µM) in the range of observed ...
The Long-term Effects of Laser Photocoagulation Treatment in
... laser photocoagulation for proliferative diabetic retinopathy was demonstrated in the Diabetic Retinopathy Study (DRS).3 Treatment with photocoagulation, either laser or xenon arc, reduced the rate of severe vision loss (visual acuity of worse than 5/200 for at least 4 months’ duration) by 50%. This ...
... laser photocoagulation for proliferative diabetic retinopathy was demonstrated in the Diabetic Retinopathy Study (DRS).3 Treatment with photocoagulation, either laser or xenon arc, reduced the rate of severe vision loss (visual acuity of worse than 5/200 for at least 4 months’ duration) by 50%. This ...
Aritavi gastro-resistant capsule, hard ENG SmPC
... abrupt (see section 4.8). In clinical trials adverse events seen on abrupt treatment discontinuation occurred in approximately 45 % of patients treated with duloxetine and 23 % of patients taking placebo. The risk of withdrawal symptoms seen with SSRI’s and SNRI’s may be dependent on several factors ...
... abrupt (see section 4.8). In clinical trials adverse events seen on abrupt treatment discontinuation occurred in approximately 45 % of patients treated with duloxetine and 23 % of patients taking placebo. The risk of withdrawal symptoms seen with SSRI’s and SNRI’s may be dependent on several factors ...
Warfarin Therapy in Haemodialysis patients. doc
... • Elderly: The elderly may be more sensitive to anticoagulant therapy. • Ovulating women: May be at risk of developing ovarian hemorrhage at the time of ovulation. • Patients with genomic variants in CYP2C9 and/or VKORC1: Presence of the CYP2C9*2 or *3 allele and/or polymorphism of the vitamin K oxi ...
... • Elderly: The elderly may be more sensitive to anticoagulant therapy. • Ovulating women: May be at risk of developing ovarian hemorrhage at the time of ovulation. • Patients with genomic variants in CYP2C9 and/or VKORC1: Presence of the CYP2C9*2 or *3 allele and/or polymorphism of the vitamin K oxi ...
Product information for strontium ranelate
... ranelic acid have been assessed in healthy young men and healthy postmenopausal women, as well as during long-term exposure in postmenopausal osteoporotic women including elderly women. Due to its high polarity, the absorption, distribution and binding to plasma proteins of ranelic acid are low. The ...
... ranelic acid have been assessed in healthy young men and healthy postmenopausal women, as well as during long-term exposure in postmenopausal osteoporotic women including elderly women. Due to its high polarity, the absorption, distribution and binding to plasma proteins of ranelic acid are low. The ...
Pseudomonas aeruginosa infection in cystic fibrosis Infection and Drug Resistance Dove
... in documenting stability or progression of airway obstruction and air trapping. These tests are also useful to detect acute changes associated with pulmonary exacerbations and response to therapy.6 The earliest spirometric evidence of obstructive disease is a decrease in expiratory flows at low volu ...
... in documenting stability or progression of airway obstruction and air trapping. These tests are also useful to detect acute changes associated with pulmonary exacerbations and response to therapy.6 The earliest spirometric evidence of obstructive disease is a decrease in expiratory flows at low volu ...
Product information for strontium ranelate
... (DRESS)] have been reported with the use of PROTOS. Patients should be advised of the signs and symptoms and monitored closely for skin reactions. The highest risk for occurrence of SJS or TEN is within the first weeks of treatment and usually around 3-6 weeks for DRESS. If symptoms or signs of SJS ...
... (DRESS)] have been reported with the use of PROTOS. Patients should be advised of the signs and symptoms and monitored closely for skin reactions. The highest risk for occurrence of SJS or TEN is within the first weeks of treatment and usually around 3-6 weeks for DRESS. If symptoms or signs of SJS ...
Drug Interactions Among HIV Patients Receiving
... 1996 represented a huge breakthrough in the treatment of HIV. The approach has changed a previously fatal disease into one that is chronic but manageable. However, antiretroviral therapy (ART) has been implicated in significant interactions with a variety of drug classes used to treat comorbid condi ...
... 1996 represented a huge breakthrough in the treatment of HIV. The approach has changed a previously fatal disease into one that is chronic but manageable. However, antiretroviral therapy (ART) has been implicated in significant interactions with a variety of drug classes used to treat comorbid condi ...
Renerve P - SR
... suggestive of physical dependence. The patient should be informed about this at the start of the treatment. Convulsions, including status epilepticus and grand mal convulsions, may occur during pregabalin use or shortly after discontinuing pregabalin. Concerning discontinuation of long-term treatmen ...
... suggestive of physical dependence. The patient should be informed about this at the start of the treatment. Convulsions, including status epilepticus and grand mal convulsions, may occur during pregabalin use or shortly after discontinuing pregabalin. Concerning discontinuation of long-term treatmen ...
triumeq - GSK Source
... interferon alfa with or without ribavirin. Discontinue TRIUMEQ as medically appropriate and consider dose reduction or discontinuation of interferon alfa, ribavirin, or both. (5.4) • Immune reconstitution syndrome and redistribution/accumulation of body fat have been reported in patients treated wit ...
... interferon alfa with or without ribavirin. Discontinue TRIUMEQ as medically appropriate and consider dose reduction or discontinuation of interferon alfa, ribavirin, or both. (5.4) • Immune reconstitution syndrome and redistribution/accumulation of body fat have been reported in patients treated wit ...
Insert Slide Title Here - Academy for Infection Management
... pathogens in nosocomial infections has increased at an alarming rate over the past few years • 50–60% of the >2 million nosocomial infections occurring in the USA each year are caused by antibiotic-resistant bacteria • The high rate of antibiotic resistance increases morbidity, mortality and costs a ...
... pathogens in nosocomial infections has increased at an alarming rate over the past few years • 50–60% of the >2 million nosocomial infections occurring in the USA each year are caused by antibiotic-resistant bacteria • The high rate of antibiotic resistance increases morbidity, mortality and costs a ...
Only for the use of Medical Professionals
... congestive heart failure resistant oedema associated with secondary hyperaldosteronism swelling due to excess fluid retention hepatic cirrhosis with ascites Dosage and administration For adult Dilup 20/50: 1 to 4 tablets daily according to patient’s response Dilup 40/50: 1 to 2 tablets daily for pat ...
... congestive heart failure resistant oedema associated with secondary hyperaldosteronism swelling due to excess fluid retention hepatic cirrhosis with ascites Dosage and administration For adult Dilup 20/50: 1 to 4 tablets daily according to patient’s response Dilup 40/50: 1 to 2 tablets daily for pat ...
Pediatric Codeine Formularly Restriction
... Fasting or acutely malnourished and/or dehydrated due to vomiting, diarrhea or fever (reduced hepatic glutathione stores) ...
... Fasting or acutely malnourished and/or dehydrated due to vomiting, diarrhea or fever (reduced hepatic glutathione stores) ...
ISOPTIN Ò SR 240mg
... about 12 hours, and AUC (0-) of 1,300ng-hr/mL. When Isoptin SR was administered to fasting subjects, peak plasma verapamil concentration was 92ng/mL, time to peak plasma verapamil concentration was about 7 hours, and AUC (0-) was 1,270ng-hr/mL. Similar results were demonstrated for plasma norverap ...
... about 12 hours, and AUC (0-) of 1,300ng-hr/mL. When Isoptin SR was administered to fasting subjects, peak plasma verapamil concentration was 92ng/mL, time to peak plasma verapamil concentration was about 7 hours, and AUC (0-) was 1,270ng-hr/mL. Similar results were demonstrated for plasma norverap ...
- University of Mississippi
... become limp and unexpectedly drop to the ground. These seizures are also referred to as drop attacks and often result in injury (“Types of Seizures”, 2016). Unlike generalized seizures, in focal/partial seizures consciousness is not lost and the region of the brain affected is limited to a particul ...
... become limp and unexpectedly drop to the ground. These seizures are also referred to as drop attacks and often result in injury (“Types of Seizures”, 2016). Unlike generalized seizures, in focal/partial seizures consciousness is not lost and the region of the brain affected is limited to a particul ...
Anti-malarial drugs [PPT]
... Pharmacokinetics • Oral • Widely distributed & concentrated in tissues like liver, spleen, kidney, lungs (several hundred-fold), skin, leucocytes and some other tissues • Its selective accumulation in retina is responsible for the ocular toxicity seen with prolonged use ...
... Pharmacokinetics • Oral • Widely distributed & concentrated in tissues like liver, spleen, kidney, lungs (several hundred-fold), skin, leucocytes and some other tissues • Its selective accumulation in retina is responsible for the ocular toxicity seen with prolonged use ...
Adverse events associated with dietary supplements - Direct-MS
... frequency between callers. Of patients whose sex was known, 54% (415) were women. Table 2 shows the distribution of patients’ ages. Only 6 (9%) of the 67 children with symptoms under age 12 years developed more than mild symptoms, but 48 (72%) of these exposures were the result of unintentional inge ...
... frequency between callers. Of patients whose sex was known, 54% (415) were women. Table 2 shows the distribution of patients’ ages. Only 6 (9%) of the 67 children with symptoms under age 12 years developed more than mild symptoms, but 48 (72%) of these exposures were the result of unintentional inge ...
Buprenorphine Bluefish sublingual tablet ENG SmPC
... chronic hepatitis C, alcohol abuse, anorexia, other mitochondrial toxins such as acetylsalicylic acid, isoniazide, valproate, amiodarone, anti-retro-virale nucleoside analogue etc.) may increase the occurrence of such hepatic injuries. These supplemental factors should be considered before prescribi ...
... chronic hepatitis C, alcohol abuse, anorexia, other mitochondrial toxins such as acetylsalicylic acid, isoniazide, valproate, amiodarone, anti-retro-virale nucleoside analogue etc.) may increase the occurrence of such hepatic injuries. These supplemental factors should be considered before prescribi ...
Oxycodone Vitabalans film
... The usual starting dose for opioid naive patients is 5 mg every 6 hours. The dose may be increased in steps of 25% to 50% of the respective dose. The aim is a patient-specific dosage which allows for adequate analgesia with tolerable undesirable effects. Therefore, the dosing interval may be shorten ...
... The usual starting dose for opioid naive patients is 5 mg every 6 hours. The dose may be increased in steps of 25% to 50% of the respective dose. The aim is a patient-specific dosage which allows for adequate analgesia with tolerable undesirable effects. Therefore, the dosing interval may be shorten ...
Drug Safety 24: 255
... sildenafil and ED). The key words used in the search were: sildenafil, erectile dysfunction, impotence. The second step was a ‘hand search’ of the available publications, mostly based on examination of reference lists from articles found on Medline. Additional data were also acquired through a searc ...
... sildenafil and ED). The key words used in the search were: sildenafil, erectile dysfunction, impotence. The second step was a ‘hand search’ of the available publications, mostly based on examination of reference lists from articles found on Medline. Additional data were also acquired through a searc ...
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS 1
... related to idiopathic or heritable PAH and PAH associated with connective tissue disease. The use of riociguat in other forms of PAH not studied is not recommended (see section 5.1). In chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy is the treatment of choice as it is a pote ...
... related to idiopathic or heritable PAH and PAH associated with connective tissue disease. The use of riociguat in other forms of PAH not studied is not recommended (see section 5.1). In chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy is the treatment of choice as it is a pote ...
Bisoprolol Fumarate 1.25 mg, 2.5 mg, 5 mg and 10 mg Tablets
... Combination of bisoprolol fumarate with calcium antagonists of the verapamil and diltiazem type, with Class I antiarrhythmic drugs and with centrally acting antihypertensive drugs is generally not recommended, for details please refer to section 4.5. In bronchial asthma or other chronic obstructive ...
... Combination of bisoprolol fumarate with calcium antagonists of the verapamil and diltiazem type, with Class I antiarrhythmic drugs and with centrally acting antihypertensive drugs is generally not recommended, for details please refer to section 4.5. In bronchial asthma or other chronic obstructive ...
Ofloxacin
Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.