Pravin R - Pivot Pharmaceuticals
... Build and enhance the pipeline value of the company through development of early-stage preclinical assets of the company across GI, diabetes and cancer areas Integrated all the scientific and operational activities of the company across multiple sites in the United States and in India Led the Joint ...
... Build and enhance the pipeline value of the company through development of early-stage preclinical assets of the company across GI, diabetes and cancer areas Integrated all the scientific and operational activities of the company across multiple sites in the United States and in India Led the Joint ...
Bioremediation
... compounds are released into the environment each year as a result of human activities. The release may be: Deliberate and well regulated (industrial emissions) Accidental and largely unavoidable (chemical/oil ...
... compounds are released into the environment each year as a result of human activities. The release may be: Deliberate and well regulated (industrial emissions) Accidental and largely unavoidable (chemical/oil ...
Homeostasis - MF011 General Biology 2
... Under hormonal control as they excrete wastes and salts ...
... Under hormonal control as they excrete wastes and salts ...
Cefalexin
... peak plasma concentration of about 18 micrograms/mL occurs 1 hour after a 500-mg oral dose. If cefalexin is taken with food, absorption may be delayed, but the total amount absorbed is not appreciably altered. Up to 15% of a dose is bound to plasma proteins. The plasma half-life is about 1 hour; it ...
... peak plasma concentration of about 18 micrograms/mL occurs 1 hour after a 500-mg oral dose. If cefalexin is taken with food, absorption may be delayed, but the total amount absorbed is not appreciably altered. Up to 15% of a dose is bound to plasma proteins. The plasma half-life is about 1 hour; it ...
P97
... variation. Frusemide treatment is known to induce renal renin release. (6) whereas the intrarenal adenosine, acting synergistically with angiotensin II, a renin metabolite, mediates the tubuloglomerular feedback, (7) which is blocked by theophylline, an adenosine receptor antagonist. (8) Aim: To rep ...
... variation. Frusemide treatment is known to induce renal renin release. (6) whereas the intrarenal adenosine, acting synergistically with angiotensin II, a renin metabolite, mediates the tubuloglomerular feedback, (7) which is blocked by theophylline, an adenosine receptor antagonist. (8) Aim: To rep ...
Module I
... Rates of heroin use are declining among youth • 8th grade use peaked in 1996 • 10th grade use peaked in 1997 • 12th grade use peaked in 2000 Rates of non-medical use of opioids are increasing • Rates in all ages peaked in 2007 • Rates highest in 18-25 year olds ...
... Rates of heroin use are declining among youth • 8th grade use peaked in 1996 • 10th grade use peaked in 1997 • 12th grade use peaked in 2000 Rates of non-medical use of opioids are increasing • Rates in all ages peaked in 2007 • Rates highest in 18-25 year olds ...
Psychoactive plants used in designer drugs as a
... nervousness [13]. Jeet et al. [12] have shown that methanol and ethyl acetate extracts of whole aerial part of Argyreia nervosa have antipyretic activity in animal model, but the exact active principle responsible for this effect is still unknown. Subramoniam et al. [14] investigated the aphrodisiac ...
... nervousness [13]. Jeet et al. [12] have shown that methanol and ethyl acetate extracts of whole aerial part of Argyreia nervosa have antipyretic activity in animal model, but the exact active principle responsible for this effect is still unknown. Subramoniam et al. [14] investigated the aphrodisiac ...
Woody - CTN Dissemination Library
... of psychotherapies produce approximately equal outcomes of mild/moderate effect sizes – Disappointing to investigators, but useful if the therapy increases costs but does not add benefits ...
... of psychotherapies produce approximately equal outcomes of mild/moderate effect sizes – Disappointing to investigators, but useful if the therapy increases costs but does not add benefits ...
Chapter 13 Soil and Its Uses
... bury and kill vegetation, and fill drainage and irrigation ditches. Water erosion will also pollute the runoff by the chemical pesticides and fertilizers remained in the water-carried particles.) c. Wind is an important mover of soil. It may not be as evident as water erosion, since it does not leav ...
... bury and kill vegetation, and fill drainage and irrigation ditches. Water erosion will also pollute the runoff by the chemical pesticides and fertilizers remained in the water-carried particles.) c. Wind is an important mover of soil. It may not be as evident as water erosion, since it does not leav ...
How to do an enquiry on interactions between complementary or
... therapeutic window such as warfarin, phenytoin and digoxin. Other patients at risk are those with poor drug clearance such as patients with kidney or liver impairment, the old and very young (5). In such patients or in those whose therapy is deemed critical e.g. patients receiving chemotherapy, it m ...
... therapeutic window such as warfarin, phenytoin and digoxin. Other patients at risk are those with poor drug clearance such as patients with kidney or liver impairment, the old and very young (5). In such patients or in those whose therapy is deemed critical e.g. patients receiving chemotherapy, it m ...
1 Diosynth Biotechnology – Riding the Biomanufacturing Wave
... is a certified cGMP manufacturer. However, besides benefiting from general industry growth, Diosynth also enjoys some advantages by virtue of its function as a CMO. While large biotechnology or pharmaceutical firms are able to provide add-on services, they lack the agility of smaller firms, given th ...
... is a certified cGMP manufacturer. However, besides benefiting from general industry growth, Diosynth also enjoys some advantages by virtue of its function as a CMO. While large biotechnology or pharmaceutical firms are able to provide add-on services, they lack the agility of smaller firms, given th ...
Phyto-phospholipid complex vesicles for phytoconstituents and
... overviews recent advance in phytosome technology, their application for various standardized herbal extracts and aims to provide complete scientific information about phytosomes as promising drug delivery system. Keywords: Phytosomes, Phyto-phospholipid complex, Phospholipid, Herbal Extract ...
... overviews recent advance in phytosome technology, their application for various standardized herbal extracts and aims to provide complete scientific information about phytosomes as promising drug delivery system. Keywords: Phytosomes, Phyto-phospholipid complex, Phospholipid, Herbal Extract ...
Geriatrics
... ■ By 2040 the number of elderly over the age of 85 is expected to increase to 14.1 million ■ Polypharmacy is a huge issue in the elderly – Defined as 5 or more medications for a single patient (does not include supplements/vitamins). – Polypharmacy increases with age. Patient is assisted living comm ...
... ■ By 2040 the number of elderly over the age of 85 is expected to increase to 14.1 million ■ Polypharmacy is a huge issue in the elderly – Defined as 5 or more medications for a single patient (does not include supplements/vitamins). – Polypharmacy increases with age. Patient is assisted living comm ...
Parkinsonism
... Pyridoxine reversal of levodopa – do not occur On/Off effect – minimum Better overall improvement of patient ...
... Pyridoxine reversal of levodopa – do not occur On/Off effect – minimum Better overall improvement of patient ...
Isoniazid, rifampicin and pyrazinamide plasma concentrations 2 and
... case of PZA, the majority of our patients had concentrations within the target range, which is perhaps due to the wide reference range for PZA (20–50 μg /ml). The prevalence of low drug plasma concentration is common and has been studied previously.10,18,19 In Tappero et al., 30% of patients had low ...
... case of PZA, the majority of our patients had concentrations within the target range, which is perhaps due to the wide reference range for PZA (20–50 μg /ml). The prevalence of low drug plasma concentration is common and has been studied previously.10,18,19 In Tappero et al., 30% of patients had low ...
McKim Chapter 9 - FIT ABA Materials: Eb Blakely
... Rohypnol is one of the drugs most commonly implicated in drug-facilitated rape. It can mentally and physically paralyze an individual. Effects of the drug are of particular concern in combination with alcohol and can lead to anterograde amnesia, where events that occurred during the time the drug wa ...
... Rohypnol is one of the drugs most commonly implicated in drug-facilitated rape. It can mentally and physically paralyze an individual. Effects of the drug are of particular concern in combination with alcohol and can lead to anterograde amnesia, where events that occurred during the time the drug wa ...
Public Assessment Report Scientific discussion AlendroSteo Kit 70
... medicine was assessed and its authorisation recommended as well as its conditions of use. It is not intended to provide practical advice on how to use AlendroSteo Kit. For practical information about using this medicine, patients should read the package leaflet or contact their doctor or pharmacist. ...
... medicine was assessed and its authorisation recommended as well as its conditions of use. It is not intended to provide practical advice on how to use AlendroSteo Kit. For practical information about using this medicine, patients should read the package leaflet or contact their doctor or pharmacist. ...
Pharmaceuticals utilized in stem cell transplant
... malignant B and T lymphocytes, NK cells, monocytes and macrophages FDA approved for the treatment of B-cell chronic lymphocytic leukemia in patients who have been treated with alkylating agents and have failed ...
... malignant B and T lymphocytes, NK cells, monocytes and macrophages FDA approved for the treatment of B-cell chronic lymphocytic leukemia in patients who have been treated with alkylating agents and have failed ...
GenOne™ Spray
... systemic use of synthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs. Cushing’s syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. PRECAUTIONS: Antibiotic susceptibility of the pathogenic organism(s) shou ...
... systemic use of synthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs. Cushing’s syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. PRECAUTIONS: Antibiotic susceptibility of the pathogenic organism(s) shou ...
B-8 - New Psychiatric Medications
... • Starting dose 1 mg twice daily • Target dosage range 6-12 mg twice daily • Increase by no more than 2 mg twice daily every day until target range – Slow titration due to increased risk of low blood pressure, dizziness, and falls ...
... • Starting dose 1 mg twice daily • Target dosage range 6-12 mg twice daily • Increase by no more than 2 mg twice daily every day until target range – Slow titration due to increased risk of low blood pressure, dizziness, and falls ...
Miconazole - Antimicrobe.org
... Contraindications/Warnings/Precautions: Precautions: None Drug Interactions: Clotrimazole is an inhibitor of the cytochrome P450 3A4, 2A6, 2C8/9, and 2E1, 2C19, 2D6 isoenzymes. Caution should be exercised and monitoring is suggested when concomitantly administering miconazole with drugs that have n ...
... Contraindications/Warnings/Precautions: Precautions: None Drug Interactions: Clotrimazole is an inhibitor of the cytochrome P450 3A4, 2A6, 2C8/9, and 2E1, 2C19, 2D6 isoenzymes. Caution should be exercised and monitoring is suggested when concomitantly administering miconazole with drugs that have n ...
Wettability - IVT Network
... The efficiency and effectiveness of this coating is very dependent on the wettabilities involved. Good wetting properties are required to get uniform liquid distribution and well controlled granule growth. If the solids have low wetting (i.e., high contact angles) the film will not be created and th ...
... The efficiency and effectiveness of this coating is very dependent on the wettabilities involved. Good wetting properties are required to get uniform liquid distribution and well controlled granule growth. If the solids have low wetting (i.e., high contact angles) the film will not be created and th ...
PHYTOSOMES: A NOVEL DOSAGE FORM FOR ENHANCEMENT OF BIOAVAILABILITY OF BOTANICALS AND NEUTRACEUTICALS Review Article
... existing natural molecules. Toxicity and limited absorption of different phytoconstituents obtained from herbs are major problems in exploring their real potentials against different diseases. So, extensive research in the field of herbal drug delivery systems as a means of impr ...
... existing natural molecules. Toxicity and limited absorption of different phytoconstituents obtained from herbs are major problems in exploring their real potentials against different diseases. So, extensive research in the field of herbal drug delivery systems as a means of impr ...
Toxicology and safety pharmacology and metabolic studies
... – Understand effects on efflux/influx transporters – Determine which CYPs are responsible for drug metabolism plus any potential for CYP induction/inhibition – Determine cross-species plasma protein binding (only unbound drug can interact with target) ...
... – Understand effects on efflux/influx transporters – Determine which CYPs are responsible for drug metabolism plus any potential for CYP induction/inhibition – Determine cross-species plasma protein binding (only unbound drug can interact with target) ...
pharmaceutical informations on the web
... US healthcare lobby groups asked the Canadian government to decrease online drug trade in Canada, because it might be dangerous for the healt of Canadian patients. Canadians were told, that if US people buy drugs from Canada, that can cause serious deficits in the selling of drugs in Canada and also ...
... US healthcare lobby groups asked the Canadian government to decrease online drug trade in Canada, because it might be dangerous for the healt of Canadian patients. Canadians were told, that if US people buy drugs from Canada, that can cause serious deficits in the selling of drugs in Canada and also ...
Environmental impact of pharmaceuticals and personal care products
The environmental impact of pharmaceuticals and personal care products (PPCPs) is largely speculative. PPCPs are substances used by individuals for personal health or cosmetic reasons and the products used by agribusiness to boost growth or health of livestock. PPCPs have been detected in water bodies throughout the world. The effects of these chemicals on humans and the environment are not yet known, but to date there is no scientific evidence that they have an impact on human health. The term PPCPs contains as well environmental persistent pharmaceutical pollutants (EPPPs). The European Union summarizes pharmaceutical residues with the potential of contamination of water and soil together with other micropollutants under “priority substances”.