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Drug utilisation sub-committee (DUSC)
Drug utilisation sub-committee (DUSC)

... Acute coronary syndrome is a term used to describe the symptoms of coronary artery disease, which include unstable angina, non-ST elevation MI and ST-elevation MI. Acute coronary syndrome is associated with atherosclerosis (build-up of cholesterol-laden plaques) and is usually precipitated by acute ...
Lack of prognostic value of heart rate variability decreased by
Lack of prognostic value of heart rate variability decreased by

... HRV in a routine clinical practice [3, 4]. However, it seems that HRV may not be useful in all coronary disease settings [5, 6]. Coronary artery bypass grafting improves survival [7], but simultaneously decreases HRV [8-11] even more than myocardial infarction does [12]. This may seem contradictory ...
Single Preconditioning Stimulus Becomes
Single Preconditioning Stimulus Becomes

... more strong ischemic challenge causes the more significant protection. There were no significant differences in hemodynamics between groups, which provides an additional evidence for local (intracardiac) nature of the protective IPC mechanism. The pattern of antiarrhythmic IPC action showed in the p ...
Diagnosis, Treatment and Prognosis of Cardiac Rupture in Acute
Diagnosis, Treatment and Prognosis of Cardiac Rupture in Acute

... to have no gender preference (3,10,20-22), although it may seem to be more frequent among women because of their lower incidence of AMI (4,5) ( Table 1 ). Most patients present a first ST segment elevation myocardial infarction (2,4,9,17,18,20), without clinically apparent heart failure (2,17,18,20) ...
Stress Myocardial Perfusion Imaging by CMR Provides Strong
Stress Myocardial Perfusion Imaging by CMR Provides Strong

... disease (CAD) continue to experience higher morbidity and mortality than men independent of age (1). Current noninvasive methods have reduced diagnostic accuracy in women leading to delayed CAD recognition and management, which have been associated with the observed adverse outcomes. Noninvasive det ...
Early Increase in Left Ventricular Compliance after Myocardial
Early Increase in Left Ventricular Compliance after Myocardial

... vessels were trimmed away and the LV was weighed to the nearest gram. Several theoretical and practical limitations of the above methodology are apparent. The relationship between the in vivo and in vitro P-V relationships is not well established. It seems reasonable to assume that the physiologic d ...
Detection and Imaging of Cardiac Allograft Vasculopathy
Detection and Imaging of Cardiac Allograft Vasculopathy

... An example of a primarily fibrotic plaque with a paucity of lymphocytes. Notice the eccentric proliferation of the intima, in contrast to the concentric intimal hyperplasia commonly seen in cardiac allograft vasculopathy (CAV). Image courtesy of Dr. ...
Antecedent hypertension and myocardial injury in patients with
Antecedent hypertension and myocardial injury in patients with

Improvement in coronary circulatory function in morbidly obese
Improvement in coronary circulatory function in morbidly obese

... SBP did not differ significantly (Table 2). Due to the higher heart rate at rest in MOB individuals, the resting RPP was significantly higher in MOB individuals than in CON. The higher RPP at rest in MOB individuals was associated with a significantly higher resting MBF than in CON (Table 2). When a ...
Primary congenital anomalies of the coronary arteries: a coronary
Primary congenital anomalies of the coronary arteries: a coronary

... From a clinical standpoint, there are reports of chest pain, myocardial infarction and sudden cardiac death related to coronary anomalies [2,5,6,15,16]. The origin of the left coronary artery from the contralateral sinus or artery, with subsequent passage between the aorta and right ventricular outf ...
Early glycoprotein IIb–IIIa inhibitors in primary - Heart
Early glycoprotein IIb–IIIa inhibitors in primary - Heart

... IIb–IIIa inhibitors. Mortality was not significantly different between groups, although early abciximab demonstrated improved survival compared with late administration, even after adjustment for clinical and angiographic confounding factors. Conclusions: This meta-analysis shows that pharmacologica ...
Acute coronary syndromes
Acute coronary syndromes

... modern treatment is down to a few percent.11 Despite this progress in cardiovascular medicine cardiovascular mortality remains high. In Sweden 4 out of 10 deaths are cardiovascular 12 and AMI is still the number one killer in the world.13 The trend is positive but threatened by increasing prevalence ...
Comparison of coronary risk scoring systems to predict the severity
Comparison of coronary risk scoring systems to predict the severity

... Oncology Education and Research Hospital. A total of 205 patients with significant CAD who underwent a coronary angiography due to a diagnosis of stable angina pectoris between January 2012 and December 2014 were included in this study. Local Ethics Committee approved the study and written consent w ...
Influence of a Nonionic, Iso-Osmolar Contrast Medium
Influence of a Nonionic, Iso-Osmolar Contrast Medium

... nonionic contrast media during percutaneous transluminal coronary angioplasty (PTCA) and the influences of these media on clinical outcome are controversial.1– 8 Thrombosis and vessel dissection may influence the clinical outcome after coronary angioplasty, a procedure that invariably damages the en ...
Metabolic Response during Impending Myocardial
Metabolic Response during Impending Myocardial

... rise which occurs in plasma glucose levels. In addition, there is recent evidence that glucose uptake by the myocardium in normal resting man is inversely related to FFA levels42 and perhaps less dependent on insulin than was previously thought. Thus, ischemic myocardial cells may in some patients b ...
The effects of daily exercise on susceptibility to sudden
The effects of daily exercise on susceptibility to sudden

... Cardiac autonomic neural function was assessed by activation of the baroreceptor reflex. The animals were given bolus injection of phenylephrine HCI (Neo-Synephrine; Winthrop Laboratories 10 jig/kg) to raise systolic arterial pressure 30 to 50 mm Hg. RR interval (and heart rate) were plotted against ...
Continuous positive airway pressure decreases myocardial oxygen
Continuous positive airway pressure decreases myocardial oxygen

induction of a chronic myocardial infarction
induction of a chronic myocardial infarction

Dual LAD – Contemporary Review
Dual LAD – Contemporary Review

... decided to write one. According to the literature, incidence of the coronary artery anomalies in general population is approximately 1% [4]. They are often not associated with clinical signs and symptoms, but some of them can lead to sudden cardiac death. According to the Sudden Death Committee of t ...
Coronary Artery Calcification: Methods and Clinical Value
Coronary Artery Calcification: Methods and Clinical Value

... tion) has significantly reduced over the last two decades; the incidence of new onset of CHD has remained stable during this period (4-6). This finding points to the fact that although we have made great strides in secondary prevention, we have failed poorly in our primary efforts of decreasing the ...
ACCF/ACR/SCCT/SCMR/ ASNC/NASCI/SCAI/SIR Appropriateness
ACCF/ACR/SCCT/SCMR/ ASNC/NASCI/SCAI/SIR Appropriateness

... CMR and related resources. Our approach is not to diminish the acknowledged ambiguity of clinical decision making for certain patients by statistical means or consensus techniques, but to recognize that real differences in clinical opinion can exist for particular patient presentation, especially in ...
Left Ventricular Mechanical Support with Impella
Left Ventricular Mechanical Support with Impella

... However, ECMO systems have device-related disadvantages such as hemolysis, coagulation disorders, and limited device durability. Furthermore, the efficacy of ECMO has been questioned with respect to the mechanoenergetic status of the heart.4,5 Adverse effects of ECMO on a failing heart are increased ...
Clinical application of genetic risk assessment strategies for
Clinical application of genetic risk assessment strategies for

... medical therapy including niacin and fibrates [119,120], and avoidance of bblockers if possible [121]. Fish oil supplementation also improves the lipid profile associated with ALP [122]. Modifying ALP with the aforementioned measures, particularly niacin alone or in combination with other lipidlowerin ...
Delayed Systolic Blood Pressure Recovery After Graded Exercise
Delayed Systolic Blood Pressure Recovery After Graded Exercise

... with a resting SBP ⬎140 mm Hg or a resting diastolic blood pressure ⬎90 mm Hg, or treatment with antihypertensive medications, were defined as having resting hypertension (10). Vital signs including weight were obtained by direct measurement. All these data, as well as stress test data, were entered ...
Stress Echo
Stress Echo

... Myocardial perfusion imaging is also often used as an initial test to evaluate the presence, and extent of coronary disease. Like stress echocardiography it is also used to stratify the risk for patients with and without significant disease. Similar to all stress testing MPI can be used for monitori ...
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