Genome Projector: zoomable genome map with multiple views
... UniProt, and NCBI, and a 3D protein structure when it is available from the Protein Data Bank (PDB) [27]. The main region showing the map can be used in the same way as Google Maps; for example, mouse click and drag moves the visible region, and mouse scroll wheel or double clicking allows zooming. ...
... UniProt, and NCBI, and a 3D protein structure when it is available from the Protein Data Bank (PDB) [27]. The main region showing the map can be used in the same way as Google Maps; for example, mouse click and drag moves the visible region, and mouse scroll wheel or double clicking allows zooming. ...
Preparation of single rice chromosome for construction of a DNA
... The construction of a rice chromosome-specific library would be helpful in genome mapping because it will provide chromosomal specific sequences for developing genetic markers. In the present study, optical scissors and optical trap were utilized in the isolation of a single chromosome from a metaph ...
... The construction of a rice chromosome-specific library would be helpful in genome mapping because it will provide chromosomal specific sequences for developing genetic markers. In the present study, optical scissors and optical trap were utilized in the isolation of a single chromosome from a metaph ...
Supplementary Data - Word file
... order and orientation and cluster them. The orientation of each cluster is either "+" or "-" (defined as expected from the given coordinate system). Create a list, L, of these seed clusters. Step2: Initialize the Cluster Distance Matrix. Define the bounds of a cluster as its endpoints on each axis o ...
... order and orientation and cluster them. The orientation of each cluster is either "+" or "-" (defined as expected from the given coordinate system). Create a list, L, of these seed clusters. Step2: Initialize the Cluster Distance Matrix. Define the bounds of a cluster as its endpoints on each axis o ...
Genetic of PWS – Explanation for the Rest of Us - Prader
... In this less common form of PWS, the baby inherits both copies of chromosome 15 from one parent—the mother. (Maternal means mother; uniparental means one parent; and disomy means two chromosome bodies). In these cases, the developing baby usually starts out with three copies of chromosome 15 (a cond ...
... In this less common form of PWS, the baby inherits both copies of chromosome 15 from one parent—the mother. (Maternal means mother; uniparental means one parent; and disomy means two chromosome bodies). In these cases, the developing baby usually starts out with three copies of chromosome 15 (a cond ...
Supplementary Figure Legends (doc 34K)
... harbour a complete or partial deletion of the NF1 locus as confirmed by real-time PCR-based gene dosage. Custom high resolution array-CGH enables the accurate characterization of the deletion type. NF1 complete and large partial deletions were observed in 4.2% and 0.5% of NF1 patients in the French ...
... harbour a complete or partial deletion of the NF1 locus as confirmed by real-time PCR-based gene dosage. Custom high resolution array-CGH enables the accurate characterization of the deletion type. NF1 complete and large partial deletions were observed in 4.2% and 0.5% of NF1 patients in the French ...
Clinical Findings in Chromosome Aberrations
... o Congenital malformations omphalocele congenital heart defects renal malformations, large bladder due to urethral obstruction, abnormal male genitalia cleft lip and palate holoprosencephaly and other brain malformations hexadactyly, radial hypo-/aplasia ...
... o Congenital malformations omphalocele congenital heart defects renal malformations, large bladder due to urethral obstruction, abnormal male genitalia cleft lip and palate holoprosencephaly and other brain malformations hexadactyly, radial hypo-/aplasia ...
RECIPROCAL CHROMOSOME TRANSLOCATIONS IN 437
... al. 2008a, 2008b). There is an increased risk for males with autosomal abnormalities to have oligospermia, and chromosome studies on spermatozoa show an unbalanced karyotype in variable proportions, e.g. 54% for reciprocal translocations and 13.7% for Robertsonian translocations (Martin et al. 1993) ...
... al. 2008a, 2008b). There is an increased risk for males with autosomal abnormalities to have oligospermia, and chromosome studies on spermatozoa show an unbalanced karyotype in variable proportions, e.g. 54% for reciprocal translocations and 13.7% for Robertsonian translocations (Martin et al. 1993) ...
Gene mapping and medical genetics Human chromosome 8
... use in cardiac disease. Since chromosome 8 represents about 5% of the human genome, we may expect it to carry about 5% of human gene loci. This would correspond to about 90 of the fully validated phenotypes in the MIM7 catalogue.' The 27 genes assigned to chromosome 8 at the Ninth Human Gene Mapping ...
... use in cardiac disease. Since chromosome 8 represents about 5% of the human genome, we may expect it to carry about 5% of human gene loci. This would correspond to about 90 of the fully validated phenotypes in the MIM7 catalogue.' The 27 genes assigned to chromosome 8 at the Ninth Human Gene Mapping ...
NEW EVIDENCE FOR THE HOMOLOGY OF THE SHORT
... and in the distal half of the 19th section (but to the left of the rightmost break of the inversion associated with the mutant C e ) . The break in IIIR is located at approximately one fifth the length from the distal end. The long, middle part of the X chromosome, to the proximal end of which the s ...
... and in the distal half of the 19th section (but to the left of the rightmost break of the inversion associated with the mutant C e ) . The break in IIIR is located at approximately one fifth the length from the distal end. The long, middle part of the X chromosome, to the proximal end of which the s ...
Evolution of Gene Order and Chromosome Number in
... the lineage leading to K. lactis, and proposed that all 55 duplicated chromosomal regions arose simultaneously in a whole-genome duplication making yeast, in effect, a degenerate tetraploid. Some regions of the K. lactis genome have gene orders that correspond to an amalgamation of genes from both c ...
... the lineage leading to K. lactis, and proposed that all 55 duplicated chromosomal regions arose simultaneously in a whole-genome duplication making yeast, in effect, a degenerate tetraploid. Some regions of the K. lactis genome have gene orders that correspond to an amalgamation of genes from both c ...
Slides
... Mapping Structural Variation in Humans >1 kb segments - Structural Variations are Common 40% of the genome -Structural Variations are involved in phenotype variation and disease - Until recently most methods for detection were low resolution (>50 kb) ...
... Mapping Structural Variation in Humans >1 kb segments - Structural Variations are Common 40% of the genome -Structural Variations are involved in phenotype variation and disease - Until recently most methods for detection were low resolution (>50 kb) ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
... (inter) once for the entire genome, then the intra-chromosome simulator (intra) once for each chromosome. This process is called a cycle. The output from one cycle can be used as input to another cycle. It is generally better to run many short cycles rather than one or a few long cycles as longer cy ...
An organism containing a normal chromosome complement and
... (III) from which it was derived or with both (V). Rarely it may be left out as a univalent at pachytene. A pentavalent (V) configuration is likely to be produced. ...
... (III) from which it was derived or with both (V). Rarely it may be left out as a univalent at pachytene. A pentavalent (V) configuration is likely to be produced. ...
How imprinting is relevant to human disease - Development
... abnormalities only when they occur in the chromosome transmitted from the mother or from the father. Thus, families with chromosomal rearrangements that come to attention because of a phenotypically abnormal child need to be re-evaluated in relation to the sex of the parent transmitting the rearrang ...
... abnormalities only when they occur in the chromosome transmitted from the mother or from the father. Thus, families with chromosomal rearrangements that come to attention because of a phenotypically abnormal child need to be re-evaluated in relation to the sex of the parent transmitting the rearrang ...
The Complete Chloroplast and Mitochondrial DNA Sequence of
... immediate ancestors, a group of algae known as ‘‘charophyte green algae’’ (e.g., Chaetosphaeridium globosum), whereas Chlorophyta contain the other green algae (e.g., Chlamydomonas reinhardtii) that form a monophyletic assemblage and are a sister group to the Streptophyta (Graham and Wilcox 2000). S ...
... immediate ancestors, a group of algae known as ‘‘charophyte green algae’’ (e.g., Chaetosphaeridium globosum), whereas Chlorophyta contain the other green algae (e.g., Chlamydomonas reinhardtii) that form a monophyletic assemblage and are a sister group to the Streptophyta (Graham and Wilcox 2000). S ...
Powerpoint template for scientific posters (Swarthmore College)
... the engrailed expression correlates with embryo lethality. If the females used to generate these embryos had reduced dosage of a factor that worked with runt to repress engrailed, that the repression of engrailed would be somewhat relieved, resulting in an increase in the viability. Results mentione ...
... the engrailed expression correlates with embryo lethality. If the females used to generate these embryos had reduced dosage of a factor that worked with runt to repress engrailed, that the repression of engrailed would be somewhat relieved, resulting in an increase in the viability. Results mentione ...
High-Resolution Single-Copy Gene Fluorescence in Situ
... maize cosmid clones on maize chromosomes by adding Cot-100 DNA to suppress the repetitive sequences presented in the probes (Sadder et al., 2000; Sadder and Weber, 2002). Recently, Koumbaris and Bass (2003) have developed a strategy to avoid the cross-hybridization of repetitive sequences using sorg ...
... maize cosmid clones on maize chromosomes by adding Cot-100 DNA to suppress the repetitive sequences presented in the probes (Sadder et al., 2000; Sadder and Weber, 2002). Recently, Koumbaris and Bass (2003) have developed a strategy to avoid the cross-hybridization of repetitive sequences using sorg ...
Chromosome anomalies course
... sequence, is imprinted and therefore silenced. AS is named after a British pediatrician, Dr. Harry Angelman, who first described the syndrome in 1965. People with AS are sometimes known as "angels", both because of the syndrome's name and because of their youthful, happy ...
... sequence, is imprinted and therefore silenced. AS is named after a British pediatrician, Dr. Harry Angelman, who first described the syndrome in 1965. People with AS are sometimes known as "angels", both because of the syndrome's name and because of their youthful, happy ...
CapeTownGenomes
... New technologies need new assembly algorithms Just as the the transition from ‘clone by clone’ approach to Whole Genome Shotgun spawned new algorithms for sequence assembly the increasing use of short-read technologies requires new assembly algorithm developments Genomics clones (30-300 kb) Phrap ...
... New technologies need new assembly algorithms Just as the the transition from ‘clone by clone’ approach to Whole Genome Shotgun spawned new algorithms for sequence assembly the increasing use of short-read technologies requires new assembly algorithm developments Genomics clones (30-300 kb) Phrap ...
Comparative Genomics of Microbes
... Gene Cluster (Genes that are part of a known metabolic pathway, are found to exist as a group) – Colinearity of gene order is referred as synteny – A conserved group of genes in the same order in two genomes as a syntenic groups or syntenic clusters – Translocation: movement of genomic part from one ...
... Gene Cluster (Genes that are part of a known metabolic pathway, are found to exist as a group) – Colinearity of gene order is referred as synteny – A conserved group of genes in the same order in two genomes as a syntenic groups or syntenic clusters – Translocation: movement of genomic part from one ...
Concept_Paper
... Genes are compact in genomic space. Introns are few, small and are not spliced in alternative forms. They comprise at most about a third of the transcribed DNA [from ref. 37]. This compactness is also evident in the related ciliate Paramecium, in which an 8- ...
... Genes are compact in genomic space. Introns are few, small and are not spliced in alternative forms. They comprise at most about a third of the transcribed DNA [from ref. 37]. This compactness is also evident in the related ciliate Paramecium, in which an 8- ...
Nematode genome evolution
... an 11-gene region sequenced from P. pacificus chromosome III, 10/11 genes had orthologs on C. elegans chromosome III (Lee et al., 2003). This led Lee et al. to suggest that P. pacificus chromosome III and C. elegans chromosome III shared a common ancestor. If this is true, there must have been a lot ...
... an 11-gene region sequenced from P. pacificus chromosome III, 10/11 genes had orthologs on C. elegans chromosome III (Lee et al., 2003). This led Lee et al. to suggest that P. pacificus chromosome III and C. elegans chromosome III shared a common ancestor. If this is true, there must have been a lot ...
A long-term demasculinization of X
... these taxa. New Drosophila retrogenes tend to escape from the X chromosome and are more likely to be expressed in testis (Betrán et al. 2002), and excessive male-biased retrogene traffic has been observed on the mammalian X chromosome (Emerson et al. 2004). Further studies showed that new DNA-based ...
... these taxa. New Drosophila retrogenes tend to escape from the X chromosome and are more likely to be expressed in testis (Betrán et al. 2002), and excessive male-biased retrogene traffic has been observed on the mammalian X chromosome (Emerson et al. 2004). Further studies showed that new DNA-based ...