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as diaspartate - Therapeutic Goods Administration
as diaspartate - Therapeutic Goods Administration

... residual solvents, assay and other relevant chemical and physical properties of the drug substance. Detailed information on impurities was provided. Impurity limits are in line with the Ph. Eur. General monograph for substances for pharmaceutical use, criteria applicable to synthetic peptides. The s ...
Prescribing Information
Prescribing Information

... CLARINEX-D 12 HOUR Extended Release Tablets are not indicated for use in pediatric patients under 12 years of age. 8.5 Geriatric Use The number of subjects (n=10) ≥65 years old treated with CLARINEX-D 12 HOUR Extended Release Tablets was too limited to make any formal statistical comparison regardin ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
HIGHLIGHTS OF PRESCRIBING INFORMATION

... The following adverse reactions have been identified during post-approval use of guanfacine. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. An op ...
About Feline Infectious Peritonitis (FIP)
About Feline Infectious Peritonitis (FIP)

... If pleural effusion occurs, the primary clinical signs may include dyspnea, tachypnea, open-mouth breathing, and cyanotic mucous membranes. Heart sounds will be muffled on thoracic auscultation. Other less common signs include ocular or central nervous system (CNS) involvement, pericardial effusion, ...
National minimum retesting intervals in pathology A final report
National minimum retesting intervals in pathology A final report

... electronic patient record is of paramount importance so that prepared logic rules or MRIs can be correctly implemented. The implementation of electronic requesting of tests provides an opportunity to improve the quality of information received from the requester for the laboratory to use. When a pro ...
Course Description - Stephen F. Austin State University
Course Description - Stephen F. Austin State University

... Ordinarily, at the discretion of the instructor of record and with the approval of the academic chair/director, a grade of WH will be assigned only if the student cannot complete the course work because of unavoidable circumstances. Students must complete the work within one calendar year form the e ...
Checking semantic consistency: temporal constraints
Checking semantic consistency: temporal constraints

... This property is important especially at execution time, since, in such a way, the execution tool can provide specific support to the user physicians whenever they have to choose from alternatives; (ii) checks that decision actions are preceded by query actions specifying all the data involved in th ...
Guideline on clinical investigation of medicinal - EMA
Guideline on clinical investigation of medicinal - EMA

... agents, the mechanism of action of the drug should be evaluated and discussed. If there are pharmacologically active metabolites, the contribution to therapeutic and/or toxic effects should be discussed. ...
Clinical Casemix Handbook 2012-2014 Version 3.0
Clinical Casemix Handbook 2012-2014 Version 3.0

... The quality of the information in a patient’s medical record is a key element of the safety and quality of the care we deliver. Accurate and timely health information is vital to safe and effective handover of care between healthcare professionals. Good documentation ensures that all clinical staff ...
Economic effects of clinical pharmacy interventions: A literature review
Economic effects of clinical pharmacy interventions: A literature review

... of clinical pharmacy interventions, identifies gaps in the evidence base, and proposes avenues for designing future economic evaluations of clinical pharmacy interventions. Methods Study design. A literature review focused on clinical pharmacy interventions in the hospital setting was conducted. Stu ...
Treatment-resistant obsessive-compulsive disorder (OCD): current
Treatment-resistant obsessive-compulsive disorder (OCD): current

... algorithm for those patients who fail to respond to a first SRI trial. Method: We carried out a search on MEDLINE/PUBMED database, selecting meta-analyses, systematic reviews and randomized controlled studies written in English on treatment-resistant OCD. We also considered open-label studies and ca ...
Results - KalbeMed
Results - KalbeMed

... coronary angiography were selected in 11 participating centres. Inclusion and exclusion criteria are shown in table 1. Patients were maintained on a lipid-lowering diet according to the practice of the centre. In some centres, patients were seen, regularly by a dietitian; in others, diet-counselling ...
Pharmacology
Pharmacology

... 1) Lecture. Various teaching methods are furnished in pharmacology lectures. Multimedia courseware in aid of blackboard is the common way of teaching. Animations are also used to illustrate the mechanism of drugs, making the abstracts lively and easy to understand. 2) “Problem based learning” (PBL) ...
N-Acetylcysteine in patients with Sickle Cell Disease
N-Acetylcysteine in patients with Sickle Cell Disease

... on the Quality of Life (QoL) of patients and the medical health care system. Oxidative stress is hypothesized to play a central role in its pathophysiology. This is supported by the fact that markers of oxidative stress are associated with severity of the disease. In an open label randomized pilot s ...
All students are required to complete the online orientations for
All students are required to complete the online orientations for

... calendar year form the end of the semester in which they received a WH, or the grade automatically becomes an F. If students register for the same course in future terms the WH will automatically become an F and will be counted as a repeated course for the purposes of computing the grade point avera ...
Rituximab in Relapsing and Progressive Forms of Multiple Sclerosis
Rituximab in Relapsing and Progressive Forms of Multiple Sclerosis

... Criteria for Considering Studies for this Review Types of studies. Clinical trials (any kind of clinical trial) including those versus placebo and those comparing rituximab with any other MS therapy alone or in combination. English and Spanish were considered as possible languages. Types of particip ...
DISCLAIMER STATEMENT
DISCLAIMER STATEMENT

... design, because placebo-controlled trials would be unethical to conduct even in patients that have symptoms and signs of mild pneumonia. There was support for the noninferiority clinical trial design, but the AIDAC did not reach a consensus on what the primary endpoint should be when considering the ...
anoro ellipta
anoro ellipta

... beta2-agonist than usual, these may be markers of deterioration of disease. In this setting a re-evaluation of the patient and the COPD treatment regimen should be undertaken at once. Increasing the daily dose of ANORO ELLIPTA beyond the recommended dose is not appropriate in this situation. ...
Guidelines for Registration of Fixed
Guidelines for Registration of Fixed

... finished pharmaceutical product (FDC-FPP) may be less than that of separate products given concurrently, and there are simpler logistics of distribution. Improved patient adherence and reduced development of resistance in the case of antimicrobials can be difficult to prove, but may be additional be ...
The Cochrane Collaboration
The Cochrane Collaboration

... Unbiased selection and abstraction process Critical appraisal of data Synthesis of data ...
Placebos: can you get something for nothing?
Placebos: can you get something for nothing?

... who received no treatment. In such trials, the untreated group may also improve. Problems often do heal by themselves; these are often called “natural history effects”. It is also often the case that people seek treatment (and are enrolled in trials) when their (fluctuating) symptoms are at their wor ...
Tablets CEFTIN for Oral Suspension (cefuroxime axetil tablets)
Tablets CEFTIN for Oral Suspension (cefuroxime axetil tablets)

... Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including CEFTIN, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. diffic ...
Excessive lever pressing following post
Excessive lever pressing following post

... to a compound stimulus (light+tone) and food, thus establishing the stimulus as a signal for the delivery of food. In the second stage (lever press training) rats were trained to lever press for food in a discrete-trial procedure (i.e., the levers were introduced into the operant box at the beginnin ...
| Treating allergic bronchopulmonary aspergillosis: the way forward Richard B. Moss
| Treating allergic bronchopulmonary aspergillosis: the way forward Richard B. Moss

... For reasons that remain unclear, ABPA appears to be more prevalent in south Asia than in many other regions of the world [11]; recently, investigators led by Ritesh Agarwal of the Postgraduate Institute of Medicine Education and Research in Chandigarh, India, who care for a uniquely large cohort of ...
skin touch Department of Dermatology Receives $1M Gift
skin touch Department of Dermatology Receives $1M Gift

... 6. New Program in Teledermatology ...
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Clinical trial

Clinical trials are experiments done in clinical research. Such prospective biomedical or behavioral research studies on human participants are designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial - their approval does not mean that the therapy is 'safe' or effective, only that the trial may be conducted.Depending on product type and development stage, investigators initially enroll volunteers and/or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary in size and cost, and they can involve a single research center or multiple centers, in one country or in multiple countries. Clinical study design aims to ensure the scientific validity and reproducibility of the results.Trials can be quite costly, depending on a number of factors. The sponsor may be a governmental organization or a pharmaceutical, biotechnology or medical device company. Certain functions necessary to the trial, such as monitoring and lab work, may be managed by an outsourced partner, such as a contract research organization or a central laboratory.Only 10% of all drugs started in human clinical trials become an approved drug.
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