QUALITY BY DESIGN IN INHALATION PRODUCT DEVELOPMENT
... essential to start by understanding the input materials, formulation, container closure systems, and process variables, and how these affect the critical quality attributes and therefore the finished product’s performance within the design space. The operating space is used to define the range for t ...
... essential to start by understanding the input materials, formulation, container closure systems, and process variables, and how these affect the critical quality attributes and therefore the finished product’s performance within the design space. The operating space is used to define the range for t ...
History of anticoagulant therapy
... • No specific antidote for any of the new OACs – New agents in development may solve this problem • Activated charcoal will reduce drug absorption if administered within a few hours of ingestion • Rivaroxaban & apixaban effect may be reversed by giving prothrombin complex concentrate (PCC) (limited ...
... • No specific antidote for any of the new OACs – New agents in development may solve this problem • Activated charcoal will reduce drug absorption if administered within a few hours of ingestion • Rivaroxaban & apixaban effect may be reversed by giving prothrombin complex concentrate (PCC) (limited ...
| Linezolid to treat MDR-/XDR-tuberculosis: available evidence and future scenarios Giovanni Sotgiu
... Furthermore, a group of patients was successfully treated with a lower dose (300 mg) of linezolid. The proportion of adverse events was >80% but was less elevated in the group of individuals exposed to 300 mg once a day [32, 33]. In the current issue of the European Respiratory Journal, an important ...
... Furthermore, a group of patients was successfully treated with a lower dose (300 mg) of linezolid. The proportion of adverse events was >80% but was less elevated in the group of individuals exposed to 300 mg once a day [32, 33]. In the current issue of the European Respiratory Journal, an important ...
DEVELOPMENT OF SUSTAINED RELEASE MATRIX TABLET OF TRAMADOL HYDROCHLORIDE Research Article
... objectives of ensuring safety and improving efficacy of drugs as well as patient compliance, which can be achieved by better control of plasma drug levels and less frequent dosing1. Physical blending of drug with polymer matrix, followed by direct compression, compression molding, injection molding, ...
... objectives of ensuring safety and improving efficacy of drugs as well as patient compliance, which can be achieved by better control of plasma drug levels and less frequent dosing1. Physical blending of drug with polymer matrix, followed by direct compression, compression molding, injection molding, ...
Adverse drug reactions: definitions, diagnosis, and management
... the drug if possible and specific treatment of its effects. Suspected adverse drug reactions should be reported. Surveillance methods can detect reactions and prove associations. Any substance that is capable of producing a therapeutic effect can also produce unwanted or adverse effects. The risk of ...
... the drug if possible and specific treatment of its effects. Suspected adverse drug reactions should be reported. Surveillance methods can detect reactions and prove associations. Any substance that is capable of producing a therapeutic effect can also produce unwanted or adverse effects. The risk of ...
Case Studies - Richman Chemical Inc.
... What went wrong? • Showa Denko had a 50% market share and manufactured LTryptophan with a bacterial fermentation process. ...
... What went wrong? • Showa Denko had a 50% market share and manufactured LTryptophan with a bacterial fermentation process. ...
What is Nanocrystal Technology
... Expertise in drug formulation, development, scale-up & manufacture • More than 30 products launched in 100+ countries • 15 products in clinical development • Extensive product development, scale-up and manufacturing capabilities in US and EU ...
... Expertise in drug formulation, development, scale-up & manufacture • More than 30 products launched in 100+ countries • 15 products in clinical development • Extensive product development, scale-up and manufacturing capabilities in US and EU ...
Elan Drug Technology
... Expertise in drug formulation, development, scale-up & manufacture • More than 30 products launched in 100+ countries • 15 products in clinical development • Extensive product development, scale-up and manufacturing capabilities in US and EU ...
... Expertise in drug formulation, development, scale-up & manufacture • More than 30 products launched in 100+ countries • 15 products in clinical development • Extensive product development, scale-up and manufacturing capabilities in US and EU ...
Pharmacology
... pediatrics) and many other disciplines. Pharmacology is characterized by wide range of contents and profound theories, making it an indispensable course for medical and pharmaceutical research as well as clinical and production practice. The goal of pharmacology includes: 1) to clarify the action of ...
... pediatrics) and many other disciplines. Pharmacology is characterized by wide range of contents and profound theories, making it an indispensable course for medical and pharmaceutical research as well as clinical and production practice. The goal of pharmacology includes: 1) to clarify the action of ...
ARTER & HADDENLLP
... In addition, Metabolize has devoted a significant amount of time and resources to ensure that its products are safe and effective. First, Metabolize is one of two companies which invested in animal studies to evaluate the health effects of its products. These 1994 studies evaluated an herbal compoun ...
... In addition, Metabolize has devoted a significant amount of time and resources to ensure that its products are safe and effective. First, Metabolize is one of two companies which invested in animal studies to evaluate the health effects of its products. These 1994 studies evaluated an herbal compoun ...
Pharmacology
... A particular drug might be good for more than one thing, but the drug company has to choose for which use they want to seek approval. • If the drug is ultimately approved, the approval will be for that indication only. • Later, the FDA may approve the drug to treat a different indication after condu ...
... A particular drug might be good for more than one thing, but the drug company has to choose for which use they want to seek approval. • If the drug is ultimately approved, the approval will be for that indication only. • Later, the FDA may approve the drug to treat a different indication after condu ...
drug
... • The closer the pKa value to the pH of the body fluids (generally 7.4), the greater is the change in ionization degree. ...
... • The closer the pKa value to the pH of the body fluids (generally 7.4), the greater is the change in ionization degree. ...
Clinical Trial Guidelines - Pharmacy and Poisons Board
... verify the clinical, pharmacological and/or other pharmacodynamic effects of an investigational product(s), and/or to identify any adverse reactions to an investigational product(s), and/or to study absorption, distribution, metabolism, and excretion of an investigational product(s) with the object ...
... verify the clinical, pharmacological and/or other pharmacodynamic effects of an investigational product(s), and/or to identify any adverse reactions to an investigational product(s), and/or to study absorption, distribution, metabolism, and excretion of an investigational product(s) with the object ...
achieving success in the sustained regeneration form of corporate
... subject to similar development constraints. Issues such as time-to-market and cost of development are impacted by the drug testing and marketing regulations which are administered, in the United States for example, by the Food and Drugs Administration (FDA) (Tonkens, 2005). By focusing on the pharma ...
... subject to similar development constraints. Issues such as time-to-market and cost of development are impacted by the drug testing and marketing regulations which are administered, in the United States for example, by the Food and Drugs Administration (FDA) (Tonkens, 2005). By focusing on the pharma ...
![STV(])FES O!}{(])CJ(vq POqt£/ffl1flLS](http://s1.studyres.com/store/data/016575417_1-aba7121b9567f1c5ba5243ddcf13ada3-300x300.png)
STV(])FES O!}{(])CJ(vq POqt£/ffl1flLS
... therapeutics. Prontosll (2, 4 - diaminoazobenzene - 4'-sulphanamide) introduced by Domagk in 1932 was the first chemotherapeutic agent active against bacteria. In spite of its therapeutic effects had no in vitro antibacterial activity. ...
... therapeutics. Prontosll (2, 4 - diaminoazobenzene - 4'-sulphanamide) introduced by Domagk in 1932 was the first chemotherapeutic agent active against bacteria. In spite of its therapeutic effects had no in vitro antibacterial activity. ...
ATOMOXETINE for ADHD
... In adults, the presence of symptoms of ADHD that were pre-existing in childhood should be confirmed. Third-party corroboration is desirable and atomoxetine should not be initiated when the verification of childhood ADHD symptoms is uncertain. Diagnosis cannot be made solely on the presence of one or ...
... In adults, the presence of symptoms of ADHD that were pre-existing in childhood should be confirmed. Third-party corroboration is desirable and atomoxetine should not be initiated when the verification of childhood ADHD symptoms is uncertain. Diagnosis cannot be made solely on the presence of one or ...
CHIRALITY (AS PREFORMULATION ASPECTS)
... Tao and Cooks recently reported that quantitative chiral analysis could be done by tandem MS. The method is rapid and requires very little sample. Lou recently reported that it would be useful to determine enantiomers and other structurally similar drug impurities using one rather than two analytica ...
... Tao and Cooks recently reported that quantitative chiral analysis could be done by tandem MS. The method is rapid and requires very little sample. Lou recently reported that it would be useful to determine enantiomers and other structurally similar drug impurities using one rather than two analytica ...
Nursing Pharmacology
... As the understanding of plants as drug sources became more sophisticated, researchers sought to isolate and intensify active components while avoiding harmful ones. The active components of plants vary in character and effect: • Alkaloids, the most active component in plants, react with acids to for ...
... As the understanding of plants as drug sources became more sophisticated, researchers sought to isolate and intensify active components while avoiding harmful ones. The active components of plants vary in character and effect: • Alkaloids, the most active component in plants, react with acids to for ...
the role of promotion on marketing in turkish drug industry
... Drug promotion is sensed as an important subject all arround the world. In our country, drugs are being marketed and promoted in a way forever years. But as in all sectors, some problems occur about promotion in drug sector. The main problem is the positive or negative effects on sector about the su ...
... Drug promotion is sensed as an important subject all arround the world. In our country, drugs are being marketed and promoted in a way forever years. But as in all sectors, some problems occur about promotion in drug sector. The main problem is the positive or negative effects on sector about the su ...