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sleep disturbances associated with neuropsychiatric disease
sleep disturbances associated with neuropsychiatric disease

... described electrophysiologic patterns of brain electrical activity that correlated with changes in behavioral state. Other investigators discovered that the brain itself was responsible for generating its own intrinsic electrical activity and for switching between behavioral states. Clinicoanatomic ...
Clinical Case Studies
Clinical Case Studies

... to the belief that nightmares are a normal part of early development and will decrease over time (Mindell & Cashman, 1995). However, the literature indicates that trauma-related nightmares may be long-lasting and cause significant impairment and distress (Davis & Wright, 2007). Studies with adults a ...
Author`s personal copy - Sleep, Stress, and Memory Lab
Author`s personal copy - Sleep, Stress, and Memory Lab

... a 50% greater improvement was observed (see Fig. 3B). Critically, another group of subjects was sleep deprived on the first night after training. These subjects were allowed 2 full nights of recovery sleep before being retested 3 days later. The subjects failed to show any residual learning, suggest ...
Effect of Lesions of the Ventrolateral Preoptic Nucleus on NREM and
Effect of Lesions of the Ventrolateral Preoptic Nucleus on NREM and

... Electroencephalogram/electromyogram implantation, sleep recording, and scoring The rats were anesthetized by intraperitoneal chloral hydrate (7% in saline; 350 mg / kg), prepared for aseptic surgery, and secured in a stereotaxic frame. Four electroencephalogram (EEG) electrodes were screwed onto the ...
Idiopathic Hypersomnia: A Study of 77 Cases
Idiopathic Hypersomnia: A Study of 77 Cases

... Clinical Characteristics of Patients with Idiopathic Hypersomnia Hypersomnia began at a mean ± SD age of 16.6 ± 9.4 years (range 0-46 years) with 49 of 77 patients developing symptoms under the age of 18 and, in 7 cases, worsening over several years. Some patients and their families were sure that t ...
Substance Abuse Protracted Withdrawal
Substance Abuse Protracted Withdrawal

...  These signs and symptoms begin within hours or days after last use of the substance and gradually resolve.  The length of time symptoms last depends on the particular ...
Sleep and REM sleep disturbance in the memory
Sleep and REM sleep disturbance in the memory

... Post-traumatic stress disorder (PTSD) is accompanied by disturbed sleep and an impaired ability to learn and remember extinction of conditioned fear. Following a traumatic event, the full spectrum of PTSD symptoms typically requires several months to develop. During this time, sleep disturbances suc ...
Why We Sleep: The Temporal Organization of
Why We Sleep: The Temporal Organization of

... as having deleterious effects on human health. In rats, total sleep deprivation is lethal after two to three weeks [14]. Within days, animals become hyperphagic but lose weight, a state associated with increased heart rate and energy expenditure. Body temperature subsequently drops. Animals are then ...
What Keeps Us Awake: the Neuropharmacology of Stimulants and
What Keeps Us Awake: the Neuropharmacology of Stimulants and

... studied closely for their relationship to the behavioral arousal state (see above). In contrast, the role assigned to dopamine in sleep-wake regulation has been relatively limited, mainly because the dopamine neuron firing rate varies little between sleep and wake states.58,59 However, lesions of do ...
- Sacramento - California State University
- Sacramento - California State University

... of students and has it’s own special education eligibility category (Akinbami et al., 2011.) This disorder can become a major barrier to accessing education and performing at the same level as other peers (Brock, Jimerson, & Hanson, 2009). According to the American Pediatrics Association, School psy ...
be rewarded for the Project. - Sacramento
be rewarded for the Project. - Sacramento

... of students and has it’s own special education eligibility category (Akinbami et al., 2011.) This disorder can become a major barrier to accessing education and performing at the same level as other peers (Brock, Jimerson, & Hanson, 2009). According to the American Pediatrics Association, School psy ...
Rapid eye movement sleep behaviour disorder and psychiatry: a
Rapid eye movement sleep behaviour disorder and psychiatry: a

... and sleep symptoms, albeit comparable diagnoses and psychotropic prescriptions. The psychiatric patients with RBD had more anxiety and depressive symptoms, insomnia, and nightmares, all of which are associated with anxiety and mood disturbances. In addition, nightmare is a core symptom of RBD. Altho ...
A Critical Period of Sleep for Development of Courtship Circuitry and
A Critical Period of Sleep for Development of Courtship Circuitry and

... behavior critical for species propagation and suggest that rapidly growing regions of the brain are most susceptible to sleep perturbations early in life. he ontogenetic hypothesis of sleep, proposed nearly 50 years ago, postulates that early developmental sleep is important for brain patterning (1) ...
Mechanisms of Sleep Control - UCLA Integrative Center for
Mechanisms of Sleep Control - UCLA Integrative Center for

... maximally active in NREM sleep has been identified (Eguchi and Satoh, 1980). In NREM sleep, the role of the raphe system, the midline serotonergic system of the brainstem, remains unclear. Depletion of serotonin with the synthesis inhibitor /7chlorophenylalanine (PCPA) produces insomnia that can be ...
Mammalian Sleep
Mammalian Sleep

... three surviving monotremes (egg-laying mammals) that diverged early from the main paths of mammalian evolution (see Fig. 8–4). It may seem that some characteristic of the echidna (mode of reproduction, fossorial adaptation, or low body temperature) obviates the need for PS and explains its absence, ...
PDF - UNT Digital Library
PDF - UNT Digital Library

... people with insomnia met criteria for clinical depression or anxiety while only 3% of people without insomnia met criteria for clinical depression or anxiety. In a community-based sample, people with chronic insomnia had higher rates than people without insomnia for heart disease (22% vs. 10%), hype ...
Duration of sleep contributes to next-day pain report in the
Duration of sleep contributes to next-day pain report in the

... laboratory-based sleep deprivation studies have also suggested that reductions in total sleep time are accompanied by increased sensitivity to noxious stimuli [15,17], and by decrements in endogenous pain-inhibitory processes [27]. Thus, this study’s observed association of reduced sleep time with s ...
Sleep duration varies as a function of glutamate and GABA in rat
Sleep duration varies as a function of glutamate and GABA in rat

... weighing 235–250 g were purchased from Charles River Laboratories (Wilmington, MA, USA) and housed in a temperature and humidity controlled environment. Rats were kept on a 12 h light/ dark cycle (lights on at 0600), had ad libitum access to food and water, and were allowed a minimum of 1 week for a ...
State transitions between wake and sleep, and within the
State transitions between wake and sleep, and within the

... succeed each other in an apparently simple and well-defined manner: wake to light (stage 2) sleep to deep slow wave sleep then back to light (stage 2) sleep before entry into REM sleep or wake. As indicated later, this simplicity holds only when the data are averaged over many subjects, but it does ...
Ictal SPECT in patients with rapid eye movement
Ictal SPECT in patients with rapid eye movement

... ß The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: [email protected] ...
Trazodone for the treatment of fibromyalgia
Trazodone for the treatment of fibromyalgia

... sleep [21]. Trazodone does not only increase the total duration of slow wave sleep, but has also demonstrated to reduce the alpha activity in the sleep of fibromyalgia patients [5]. It is thus possible that the beneficial effects of trazodone on sleep quality in our patients could be due to its diff ...
Nightmares and their treatment options
Nightmares and their treatment options

... of REM dreams with aggression and self-denigrating themes than those with secure attachment (McNamara et al 2011). Although the relationship between nightmares and attachment in childhood has not yet been studied, it may be hypothesized that anxious attachment in childhood may predispose to nightmar ...
Metabolic signals in sleep regulation: recent insights The Harvard
Metabolic signals in sleep regulation: recent insights The Harvard

... has a wide distribution of cognate receptors extending its effects on central as well as peripheral targets, thereby regulating various physiological mechanisms such as feeding, energy metabolism, arousal, onset of REM, reward, and autonomic function.34–38 Clinical studies have underscored the impor ...
Presentazione standard di PowerPoint
Presentazione standard di PowerPoint

... fine and behaviourally relevant neural plasticity and “complex forms of network integration” should be accompanied by a slowing down of conduction. This is in fact what we should expect with a too long node of Ranvier, which may hinder the progression of the action potential. The time seems ripe to ...
Conscious Modulation in Normal Sleep
Conscious Modulation in Normal Sleep

... side of the brain. During non-REM sleep, the same TMS stimulus elicited neural activity at the site of stimulation, without spreading beyond that point. These findings suggest that different areas of cortex indeed stop talking to each other during non-REM sleep—a stage of sleep in which people often ...
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Insomnia

Insomnia, or trouble sleeping, is a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired. While the term is sometimes used to describe a disorder demonstrated by polysomnographic or actigraphic evidence of disturbed sleep, this sleep disorder is often practically defined as a positive response to either of two questions: ""Do you experience difficulty sleeping?"" or ""Do you have difficulty falling or staying asleep?""Insomnia is most often thought of as both a medical sign and a symptom that can accompany several sleep, medical, and psychiatric disorders characterized by a persistent difficulty falling asleep and/or staying asleep or sleep of poor quality. Insomnia is typically followed by functional impairment while awake. Insomnia can occur at any age, but it is particularly common in the elderly. Insomnia can be short term (up to three weeks) or long term (above 3–4 weeks); it can lead to memory problems, depression, irritability and an increased risk of heart disease and automobile related accidents.Insomnia can be grouped into primary and secondary, or comorbid, insomnia. Primary insomnia is a sleep disorder not attributable to a medical, psychiatric, or environmental cause. It is described as a complaint of prolonged sleep onset latency, disturbance of sleep maintenance, or the experience of non-refreshing sleep. A complete diagnosis will differentiate between free-standing primary insomnia, insomnia as secondary to another condition, and primary insomnia co-morbid with one or more conditions.Cognitive behavioral therapy is useful in insomnia that is present for a long duration. Those who are having trouble sleeping sometimes turn to sleeping pills, which may help, but also may lead to substance dependency or addiction if used regularly for an extended period.
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