Dupuytren`s Disease: Diagnosis and Treatment
... Surgery is usually successful, but recurrence is common.2 Percutaneous needle aponeurotomy of the nodule is an alternative to surgery.15 The in-office fasciotomy procedure includes a percutaneous needle technique using local anesthesia; it is performed more often in Europe than in the United States. ...
... Surgery is usually successful, but recurrence is common.2 Percutaneous needle aponeurotomy of the nodule is an alternative to surgery.15 The in-office fasciotomy procedure includes a percutaneous needle technique using local anesthesia; it is performed more often in Europe than in the United States. ...
Professional Practice Guideline 10 `Antipsychotic medications as a
... In 2004, a pooled analysis by the UK Committee on Safety of Medicines of data from four published and unpublished studies of risperidone pointed to a three-fold risk of ‘cerebrovascular events’ (3.5% versus 1.2%) versus placebo. These events included non-specific neurological symptoms like dizziness ...
... In 2004, a pooled analysis by the UK Committee on Safety of Medicines of data from four published and unpublished studies of risperidone pointed to a three-fold risk of ‘cerebrovascular events’ (3.5% versus 1.2%) versus placebo. These events included non-specific neurological symptoms like dizziness ...
Identifying and Treating Preclinical and Early Osteoarthritis
... radiographically identified OA do not have elevated systemic levels of acute-phase reactants.22–24 Trials testing different anti-inflammatory approaches for OA, many used in rheumatoid arthritis, are ongoing. THE FEASIBILITY OF IDENTIFYING EARLY OSTEOARTHRITIS ...
... radiographically identified OA do not have elevated systemic levels of acute-phase reactants.22–24 Trials testing different anti-inflammatory approaches for OA, many used in rheumatoid arthritis, are ongoing. THE FEASIBILITY OF IDENTIFYING EARLY OSTEOARTHRITIS ...
The Role of Environmental Exposures in
... (PD) affecting millions of Americans. A common feature of virtually all neurodegenerative diseases is that the consequences are often devastating, with severe mental and physical effects. This is due in large part to the loss or dysfunction of neurons—a highly specialized cell type that is typically ...
... (PD) affecting millions of Americans. A common feature of virtually all neurodegenerative diseases is that the consequences are often devastating, with severe mental and physical effects. This is due in large part to the loss or dysfunction of neurons—a highly specialized cell type that is typically ...
Corticobasal Syndrome Associated With the A9D Progranulin Mutation
... includes that of corticobasal degeneration (CBD), Alzheimer disease, Pick disease, progressive supranuclear palsy, dementia lacking distinctive histopathology, CreutzfeldtJakob disease, diffuse Lewy body disease, and frontotemporal lobar degeneration with ubiquitin (Ub) and TDP-43 (TAR DNA binding p ...
... includes that of corticobasal degeneration (CBD), Alzheimer disease, Pick disease, progressive supranuclear palsy, dementia lacking distinctive histopathology, CreutzfeldtJakob disease, diffuse Lewy body disease, and frontotemporal lobar degeneration with ubiquitin (Ub) and TDP-43 (TAR DNA binding p ...
Treatment of Behavioural and Psychological Symptoms in Dementia
... over age 85 (1). The incidense doubles every five years after the age of 60 years (2). In Norway over 60 000 people suffer from dementia (3). The incidence and prevalence of dementia is increasing due to longer life expectancy of the world population. In the long term this progressive cognitive impa ...
... over age 85 (1). The incidense doubles every five years after the age of 60 years (2). In Norway over 60 000 people suffer from dementia (3). The incidence and prevalence of dementia is increasing due to longer life expectancy of the world population. In the long term this progressive cognitive impa ...
Alzheimer's disease
Alzheimer's disease (AD), also known as Alzheimer disease, or just Alzheimer's, accounts for 60% to 70% of cases of dementia. It is a chronic neurodegenerative disease that usually starts slowly and gets worse over time. The most common early symptom is difficulty in remembering recent events (short-term memory loss). As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, not managing self care, and behavioural issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to nine years.The cause of Alzheimer's disease is poorly understood. About 70% of the risk is believed to be genetic with many genes usually involved. Other risk factors include a history of head injuries, depression, or hypertension. The disease process is associated with plaques and tangles in the brain. A probable diagnosis is based on the history of the illness and cognitive testing with medical imaging and blood tests to rule out other possible causes. Initial symptoms are often mistaken for normal ageing. Examination of brain tissue is needed for a definite diagnosis. Mental and physical exercise, and avoiding obesity may decrease the risk of AD. There are no medications or supplements that decrease risk.No treatments stop or reverse its progression, though some may temporarily improve symptoms. Affected people increasingly rely on others for assistance, often placing a burden on the caregiver; the pressures can include social, psychological, physical, and economic elements. Exercise programs are beneficial with respect to activities of daily living and can potentially improve outcomes. Treatment of behavioral problems or psychosis due to dementia with antipsychotics is common but not usually recommended due to there often being little benefit and an increased risk of early death.In 2010, there were between 21 and 35 million people worldwide with AD. It most often begins in people over 65 years of age, although 4% to 5% of cases are early-onset Alzheimer's which begin before this. It affects about 6% of people 65 years and older. In 2010, dementia resulted in about 486,000 deaths. It was first described by, and later named after, German psychiatrist and pathologist Alois Alzheimer in 1906. In developed countries, AD is one of the most financially costly diseases.