Buprenorphine Bluefish sublingual tablet ENG SmPC
... chronic hepatitis C, alcohol abuse, anorexia, other mitochondrial toxins such as acetylsalicylic acid, isoniazide, valproate, amiodarone, anti-retro-virale nucleoside analogue etc.) may increase the occurrence of such hepatic injuries. These supplemental factors should be considered before prescribi ...
... chronic hepatitis C, alcohol abuse, anorexia, other mitochondrial toxins such as acetylsalicylic acid, isoniazide, valproate, amiodarone, anti-retro-virale nucleoside analogue etc.) may increase the occurrence of such hepatic injuries. These supplemental factors should be considered before prescribi ...
Physostigmine
... More Mixed Overdose • 83 unconscious or severely disoriented patients • 2 mg doses repeated until maximal effect • Followed vital signs and level of consciousness Nilsson: Ann Clin Research 1982;14:165 ...
... More Mixed Overdose • 83 unconscious or severely disoriented patients • 2 mg doses repeated until maximal effect • Followed vital signs and level of consciousness Nilsson: Ann Clin Research 1982;14:165 ...
norspan® transdermal patch - Research Review Australia
... surgery. NORSPAN® patches should be used with caution following abdominal surgery, as opioids are known to impair intestinal motility. Significant respiratory depression has been associated with buprenorphine, particularly by the intravenous route. A number of deaths have occurred when addicts have ...
... surgery. NORSPAN® patches should be used with caution following abdominal surgery, as opioids are known to impair intestinal motility. Significant respiratory depression has been associated with buprenorphine, particularly by the intravenous route. A number of deaths have occurred when addicts have ...
1. NAME OF THE MEDICINAL PRODUCT Dompicare 20 mg, film
... Because of its pharmacologic effects on transit time in the stomach and small intestine, domperidone may alter the absorption of certain drugs. The extent of absorption of drugs that disintegrate, dissolve, and/or are absorbed mainly in the stomach (e.g., digoxin) may be diminished by domperidone, w ...
... Because of its pharmacologic effects on transit time in the stomach and small intestine, domperidone may alter the absorption of certain drugs. The extent of absorption of drugs that disintegrate, dissolve, and/or are absorbed mainly in the stomach (e.g., digoxin) may be diminished by domperidone, w ...
Analgesia en pacientes con ERC
... DOSING: ADULTS or ELDERLY Doses >1.5 mg/kg body weight are not recommended. Pain management (analgesic): Oral, regular release: 30 mg every 4-6 hours as needed; patients with prior opiate exposure may require higher initial doses. Usual range: 15-120 mg every 4-6 hours as needed Oral, controlled rel ...
... DOSING: ADULTS or ELDERLY Doses >1.5 mg/kg body weight are not recommended. Pain management (analgesic): Oral, regular release: 30 mg every 4-6 hours as needed; patients with prior opiate exposure may require higher initial doses. Usual range: 15-120 mg every 4-6 hours as needed Oral, controlled rel ...
Hydrocodone Bitartrate
... Hydrocodone bitartrate is an opioid antitussive and analgesic used for the relief of cough and moderate to moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bi ...
... Hydrocodone bitartrate is an opioid antitussive and analgesic used for the relief of cough and moderate to moderately severe pain. This drug should be given in the smallest effective dose and as infrequently as possible to minimize the development of tolerance and physical dependence. Hydrocodone bi ...
4427 Naltrexone/Carers.NSW
... • Before starting medication the patient must be free from heroin for 7-10 days and up to 14 days if they have been using methadone. This means they must completely detox from opioids before they can begin taking naltrexone. The reason for this is that naltrexone will bring on immediate and possibly ...
... • Before starting medication the patient must be free from heroin for 7-10 days and up to 14 days if they have been using methadone. This means they must completely detox from opioids before they can begin taking naltrexone. The reason for this is that naltrexone will bring on immediate and possibly ...
GHB
... GHB analogs - What does it do • At lower doses, GHB has sedative effects, but, as the dose increases, GHB effects may result in sleep ,eventual coma, respiratory arrest, or death. • It is these effects that make it both a prime drug at Raves, and for Date Rape ...
... GHB analogs - What does it do • At lower doses, GHB has sedative effects, but, as the dose increases, GHB effects may result in sleep ,eventual coma, respiratory arrest, or death. • It is these effects that make it both a prime drug at Raves, and for Date Rape ...
Oxycodone and Acetaminophen Tablets USP 5
... more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products. The risk of acute liver failure is higher in indivi ...
... more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products. The risk of acute liver failure is higher in indivi ...
Opioid Therapy in Chronic Pain
... of severe pain is enough to warrant use of strong pain medications. Recent teaching has been that a report of severe pain warrants treatment with opioids if all efforts to use alternative treatments have failed. But recent evidence shows that for some pain conditions, opioids not only may not work w ...
... of severe pain is enough to warrant use of strong pain medications. Recent teaching has been that a report of severe pain warrants treatment with opioids if all efforts to use alternative treatments have failed. But recent evidence shows that for some pain conditions, opioids not only may not work w ...
Comparison of High Loading Dose Versus Usual Dose of Rectal
... each patient’s medical condition. In addition, choosing the appropriate fever treatment has been a challenging issue for a long time. Antipyretic effects of acetaminophen are equal to that of aspirin. Besides, it does not have the side effects on the gastrointestinal system and platelets function. C ...
... each patient’s medical condition. In addition, choosing the appropriate fever treatment has been a challenging issue for a long time. Antipyretic effects of acetaminophen are equal to that of aspirin. Besides, it does not have the side effects on the gastrointestinal system and platelets function. C ...
(Soma): prescribing indications
... Drug Dependence, Withdrawal and Abuse - In postmarketing experience, cases of drug abuse, dependence and withdrawal have been reported. Carisoprodol should be used with caution in addiction-prone individuals. (See DRUG ABUSE AND DEPENDENCE). Additive Effects --Since the effects of carisoprodol and a ...
... Drug Dependence, Withdrawal and Abuse - In postmarketing experience, cases of drug abuse, dependence and withdrawal have been reported. Carisoprodol should be used with caution in addiction-prone individuals. (See DRUG ABUSE AND DEPENDENCE). Additive Effects --Since the effects of carisoprodol and a ...
GBL
... having used GHB, ecstasy, cocaine and alcohol. Selfdischarged ② May 2007 BIBA from club with GHB, cocaine and ketamine intoxication. 3 tonic-clonic seizures prior to hospital. Required lorazepam and discharged home ③ Feb. 2009 Presented to ED, Self-discharged before seen ④ April 2009 BIBA following ...
... having used GHB, ecstasy, cocaine and alcohol. Selfdischarged ② May 2007 BIBA from club with GHB, cocaine and ketamine intoxication. 3 tonic-clonic seizures prior to hospital. Required lorazepam and discharged home ③ Feb. 2009 Presented to ED, Self-discharged before seen ④ April 2009 BIBA following ...
β-Blocker Ingestion: An Evidence-Based Consensus
... with stated or suspected self-harm or who are the victims of a potentially malicious administration of b-blocker should be referred to an emergency department immediately. In general, this should occur regardless of the dose reported (Grade D). 2) Patients without evidence of self-harm should have f ...
... with stated or suspected self-harm or who are the victims of a potentially malicious administration of b-blocker should be referred to an emergency department immediately. In general, this should occur regardless of the dose reported (Grade D). 2) Patients without evidence of self-harm should have f ...
Part 1 of 3 Trainers Donald Harrell Meg Rumfield
... * Includes pain relievers, tranquilizers, stimulants, sedatives Note: The and specific drug refers to a drug that was used for the first time, regardless of whether it was the first drug used or not. SAMSHA, 2009 National Survey on Drug Use and Health (September 2010). ...
... * Includes pain relievers, tranquilizers, stimulants, sedatives Note: The and specific drug refers to a drug that was used for the first time, regardless of whether it was the first drug used or not. SAMSHA, 2009 National Survey on Drug Use and Health (September 2010). ...
System-Wide Medication Related Decision Evaluation
... settings, including the ED. Safer alternatives will be displayed when codeine is ordered in this population. Swedish Epic does not currently have an interchange built and is reviewing to determine inclusion. Drug Background: Codeine is a prodrug which is converted to its active metabolite, morphin ...
... settings, including the ED. Safer alternatives will be displayed when codeine is ordered in this population. Swedish Epic does not currently have an interchange built and is reviewing to determine inclusion. Drug Background: Codeine is a prodrug which is converted to its active metabolite, morphin ...
Data Sheet
... under close surveillance and ECG monitoring considered, since cardiac effects may be additive. If the dose or administration is likely to result in high blood levels, some patients require special attention to prevent potentially dangerous side effects: • Patients with partial or complete heart bloc ...
... under close surveillance and ECG monitoring considered, since cardiac effects may be additive. If the dose or administration is likely to result in high blood levels, some patients require special attention to prevent potentially dangerous side effects: • Patients with partial or complete heart bloc ...
Data Sheet
... morphine is appropriately indicated. In these patients, an increase in the doses for pain management does not necessarily reflect a development of dependence. On the other hand, in the absence of a clear indication for a strong opioid analgesic, drug-seeking behaviour must be suspected and resisted, ...
... morphine is appropriately indicated. In these patients, an increase in the doses for pain management does not necessarily reflect a development of dependence. On the other hand, in the absence of a clear indication for a strong opioid analgesic, drug-seeking behaviour must be suspected and resisted, ...
prescribing information - Purdue Pharma (Canada)
... DILAUDID should not be consumed with alcohol as it may increase the chance of experiencing dangerous side effects, including death (see CONTRAINDICATIONS and ADVERSE REACTIONS, Sedation, and DRUG INTERACTIONS). Severe pain antagonizes the subjective and respiratory depressant actions of opioid analg ...
... DILAUDID should not be consumed with alcohol as it may increase the chance of experiencing dangerous side effects, including death (see CONTRAINDICATIONS and ADVERSE REACTIONS, Sedation, and DRUG INTERACTIONS). Severe pain antagonizes the subjective and respiratory depressant actions of opioid analg ...
These highlights do not include all the information needed
... or could represent a proarrhythmic event. Case reports in patients treated with propafenone for atrial fibrillation/flutter have included increased premature ventricular contractions (PVCs), VT, VF, torsades de pointes, asystole, and death. Overall in clinical trials with propafenone hydrochloride i ...
... or could represent a proarrhythmic event. Case reports in patients treated with propafenone for atrial fibrillation/flutter have included increased premature ventricular contractions (PVCs), VT, VF, torsades de pointes, asystole, and death. Overall in clinical trials with propafenone hydrochloride i ...
Watchful Dosing of Morphine or Morphine
... threshold dose would appear to have arisen at least in part out of concern over the rising pattern of opioid prescribing that has occurred during the past ten years in Canada and its particular association with overdose and death.1 The ‘watchful dose’ would seem to act as an alert for clinicians con ...
... threshold dose would appear to have arisen at least in part out of concern over the rising pattern of opioid prescribing that has occurred during the past ten years in Canada and its particular association with overdose and death.1 The ‘watchful dose’ would seem to act as an alert for clinicians con ...
Deadly pediatric poisons: nine common agents that kill at low doses
... conflicting, data regarding the clinical utility of calcium exist [32–35]. It seems to be most beneficial in mild toxicity, with less efficacy in cases of significant toxicity. The current recommended dose is 10% calcium chloride, 10 to 25 mg/kg (0.10–0.25 mL/kg), or 10% calcium gluconate, 30 to 75 mg/ k ...
... conflicting, data regarding the clinical utility of calcium exist [32–35]. It seems to be most beneficial in mild toxicity, with less efficacy in cases of significant toxicity. The current recommended dose is 10% calcium chloride, 10 to 25 mg/kg (0.10–0.25 mL/kg), or 10% calcium gluconate, 30 to 75 mg/ k ...
Hydromorphone Hydrochloride Injection, USP, CII (1 mg/mL)
... Respiratory depression is the chief hazard of hydromorphone hydrochloride. Respiratory depression occurs most frequently in the elderly, in the debilitated, and in those suffering from conditions accompanied by hypoxia or hypercapnia, or upper airway obstruction in whom even moderate therapeutic dos ...
... Respiratory depression is the chief hazard of hydromorphone hydrochloride. Respiratory depression occurs most frequently in the elderly, in the debilitated, and in those suffering from conditions accompanied by hypoxia or hypercapnia, or upper airway obstruction in whom even moderate therapeutic dos ...
MS Contin - Purdue Pharma
... Serious Warnings and Precautions Limitations of Use Because the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with sustained release opioid formulations, MS Contin® (morphine sulfate sustained release tablets) sh ...
... Serious Warnings and Precautions Limitations of Use Because the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with sustained release opioid formulations, MS Contin® (morphine sulfate sustained release tablets) sh ...
Oxycodone Vitabalans film
... rhinorrhoea, tremor, hyperhidrosis, anxiety, agitation, convulsions and insomnia. However, when used as intended the risk of developing physical or psychological dependence is markedly reduced. There are no data available on the actual incidence of psychological dependence in chronic pain patients. ...
... rhinorrhoea, tremor, hyperhidrosis, anxiety, agitation, convulsions and insomnia. However, when used as intended the risk of developing physical or psychological dependence is markedly reduced. There are no data available on the actual incidence of psychological dependence in chronic pain patients. ...
Dextropropoxyphene
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects. The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias. Its onset of analgesia (pain relief) is said to be 20–30 minutes and peak effects are seen about 1.5–2 hours after oral administration.Dextropropoxyphene is sometimes combined with acetaminophen or aspirin. Trade names include Darvocet-N and Di-Gesic, Darvon with APAP (for dextropropoxyphene and paracetamol) and Darvon with ASA (for dextropropoxyphene and aspirin). The British approved name (i.e. the generic name of the active ingredient) of the paracetamol/dextropropoxyphene preparation is ""co-proxamol"" (sold under a variety of brand names); however, it has been withdrawn since 2007, and is no longer available to new patients, with exceptions. The paracetamol combination(s) are known as Capadex or Di-Gesic in Australia, Lentogesic in South Africa, and Di-Antalvic in France (unlike co-proxamol, which is an approved name, these are all brand names).Dextropropoxyphene is known under several synonyms, including: Alpha-d-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate [(2S,3S)-4-(Dimethylamino)-3- methyl-1,2-diphenylbutan-2-yl] propanoate (+)-1,2-Diphenyl-2-propionoxy- 3-methyl-4-di-methylaminobutane Desoxypropiophen↑ 1.0 1.1 1.2 1.3 1.4 ↑ ↑ ↑ ↑ ↑ ↑ ↑