Postdoctoral Associate, Department of Organic Chemistry
... Reporting to the VP(R&D), this senior level position was responsible for planning, managing organizing and directing all regulatory Chemistry, Manufacturing and Controls (CMC) portion of drug development. Key responsibilities included directing the anti-infective discovery research program, taki ...
... Reporting to the VP(R&D), this senior level position was responsible for planning, managing organizing and directing all regulatory Chemistry, Manufacturing and Controls (CMC) portion of drug development. Key responsibilities included directing the anti-infective discovery research program, taki ...
,
... may back up the loss of weight observed in the test groups (table 1) is still obscure even at the level of this research. But this reason may be attributed to the reported decrease in food intake as well as water intake, during the periods of treatment of the animals as in the case of metabolic resp ...
... may back up the loss of weight observed in the test groups (table 1) is still obscure even at the level of this research. But this reason may be attributed to the reported decrease in food intake as well as water intake, during the periods of treatment of the animals as in the case of metabolic resp ...
- American Heart Journal
... for the TQT Study. Second, TQT studies in study subjects with diseases to be treated by a study drug may be infeasible if need for treatment precludes placebo treatment or crossover study design. Finally, comorbidities and concomitant medications in patients can confound QT assessment results. Given ...
... for the TQT Study. Second, TQT studies in study subjects with diseases to be treated by a study drug may be infeasible if need for treatment precludes placebo treatment or crossover study design. Finally, comorbidities and concomitant medications in patients can confound QT assessment results. Given ...
Product Information for Triptorelin Acetate
... administered to trigger ovulation. Therefore in cases of OHSS it is prudent to withhold hCG and advise the patient to refrain from coitus or to use barrier methods for at least 4 days. OHSS may progress rapidly (within 24 hours to several days) to become a serious medical event, therefore patients s ...
... administered to trigger ovulation. Therefore in cases of OHSS it is prudent to withhold hCG and advise the patient to refrain from coitus or to use barrier methods for at least 4 days. OHSS may progress rapidly (within 24 hours to several days) to become a serious medical event, therefore patients s ...
8/30/10 How to use Introduction
... • Combination therapy with valproate enhances antiepileptic effect • Very slow titration is important for better tolerability ...
... • Combination therapy with valproate enhances antiepileptic effect • Very slow titration is important for better tolerability ...
Nebulisers
... A nebuliser is a powerful drug delivery system. It converts liquid into aerosol droplets suitable for inhalation. It should only be used if recommended by the doctor, and if you would benefit from this form of treatment and even then, only under careful medical supervision. Their use is declining bu ...
... A nebuliser is a powerful drug delivery system. It converts liquid into aerosol droplets suitable for inhalation. It should only be used if recommended by the doctor, and if you would benefit from this form of treatment and even then, only under careful medical supervision. Their use is declining bu ...
GenoSure Archive : Cell-associated Viral DNA Assay for
... The success of ARV therapy for each patient is predicated on the identification of a combination of ARV drugs that is active against HIV-1. During replication, the virus may select for mutations that confer reduced susceptibility/resistance to the current ARV regimen. The ability of the virus to dev ...
... The success of ARV therapy for each patient is predicated on the identification of a combination of ARV drugs that is active against HIV-1. During replication, the virus may select for mutations that confer reduced susceptibility/resistance to the current ARV regimen. The ability of the virus to dev ...
Updates in Pharmacotherapy
... Designed to reduce interference with cations Still advised to separate cations (e.g., calcium, iron) Still need to take with plenty of water and remain upright Cost similar to risedronate Risedronate will be generic in 2014 Should not take with antacids/H2 blockers/PPIs May be useful if patients are ...
... Designed to reduce interference with cations Still advised to separate cations (e.g., calcium, iron) Still need to take with plenty of water and remain upright Cost similar to risedronate Risedronate will be generic in 2014 Should not take with antacids/H2 blockers/PPIs May be useful if patients are ...
The Antihypertensive and Lipid-Lowering Treatment to Prevent
... (stroke, from 1.40 to 1.35; and heart failure, from 1.32 to 1.26), and these differences remained statistically significant. The discrepancy is particularly obvious in black patients for stroke, as the data suggested a staggering 40% higher risk of stroke in black patients, while only 13–16% of such ...
... (stroke, from 1.40 to 1.35; and heart failure, from 1.32 to 1.26), and these differences remained statistically significant. The discrepancy is particularly obvious in black patients for stroke, as the data suggested a staggering 40% higher risk of stroke in black patients, while only 13–16% of such ...
a review on: sustained release technology
... It is possible to improve significantly the relative bioavailability of a drug that is unstable in the stomach; the most appropriate controlling unit would be one that release its content only in the intestine. The reverse in the case for those drugs that are unstable in the environment of the intes ...
... It is possible to improve significantly the relative bioavailability of a drug that is unstable in the stomach; the most appropriate controlling unit would be one that release its content only in the intestine. The reverse in the case for those drugs that are unstable in the environment of the intes ...
Product Monograph
... depersonalization. In some cases, the events occurred within several weeks of starting treatment. Rigorous clinical monitoring for suicidal ideation or other indicators of potential for suicidal behaviour is advised in patients of all ages. This includes monitoring for agitationtype emotional and be ...
... depersonalization. In some cases, the events occurred within several weeks of starting treatment. Rigorous clinical monitoring for suicidal ideation or other indicators of potential for suicidal behaviour is advised in patients of all ages. This includes monitoring for agitationtype emotional and be ...
Barbiturates (ex. phenobarbital)
... and should be utilized in conjunction with pertinent clinical information. The author of this lecture and/or handout has checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publicat ...
... and should be utilized in conjunction with pertinent clinical information. The author of this lecture and/or handout has checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publicat ...
2012 פברואר ה
... 4.6. Pregnancy and lactation 4.6.1 Use during Pregnancy Although intravaginal absorption is limited, Gyno-Daktarin vaginal capsules should only be used in the first trimester of pregnancy if, in the judgement of the physician, the potential benefits outweigh the possible risks. 4.6.2 Use during lact ...
... 4.6. Pregnancy and lactation 4.6.1 Use during Pregnancy Although intravaginal absorption is limited, Gyno-Daktarin vaginal capsules should only be used in the first trimester of pregnancy if, in the judgement of the physician, the potential benefits outweigh the possible risks. 4.6.2 Use during lact ...
Combination therapy versus monotherapy for the treatment of
... The inflammatory process is both the central feature of the RA and the focus of antirheumatic therapy. The optimal approach to the treatment of RA remains controversial. The reasons for the move away from traditional management approaches are manifold and include the realization that RA is a debilit ...
... The inflammatory process is both the central feature of the RA and the focus of antirheumatic therapy. The optimal approach to the treatment of RA remains controversial. The reasons for the move away from traditional management approaches are manifold and include the realization that RA is a debilit ...
Ecstasy and Club Drugs
... In its most common form, Ecstasy is a small tablet that is impressed with any one of a number of logos intended to attract young people. It can also be in capsule or powder form and can be injected. Among the street names for Ecstasy are Adam, X-TC, Clarity, Essence, Stacy, Lover’s Speed, Eve, etc. ...
... In its most common form, Ecstasy is a small tablet that is impressed with any one of a number of logos intended to attract young people. It can also be in capsule or powder form and can be injected. Among the street names for Ecstasy are Adam, X-TC, Clarity, Essence, Stacy, Lover’s Speed, Eve, etc. ...
Product Monograph - Ask Novartis Pharma
... If a dose is missed, a single drop should be applied as soon as possible before reverting to the regular routine. Do not use a double dose to make up for a missed dose. Administration Shake well before use. Nasolacrimal occlusion or gently closing the eyelid for two minutes after instillation is rec ...
... If a dose is missed, a single drop should be applied as soon as possible before reverting to the regular routine. Do not use a double dose to make up for a missed dose. Administration Shake well before use. Nasolacrimal occlusion or gently closing the eyelid for two minutes after instillation is rec ...
PDF
... Case 8 You are asked to recommend antithrombotic therapy for a 76 year old male with permanent non-valvular atrial fibrillation who presented 8 weeks ago with an ischemic CVA. He is currently recovering in a rehab center and has a feeding tube placed as a residual effect of the stroke. PMH: Permane ...
... Case 8 You are asked to recommend antithrombotic therapy for a 76 year old male with permanent non-valvular atrial fibrillation who presented 8 weeks ago with an ischemic CVA. He is currently recovering in a rehab center and has a feeding tube placed as a residual effect of the stroke. PMH: Permane ...
Can we predict good drugs ?
... Only some side effects fall into the remit of this approach, which assumes an off-target mechanism. Almost 46% of the predicted drug–target associations were disproved, but they were just as often confirmed by experimental ways. The method was used automatically at scale, without human interve ...
... Only some side effects fall into the remit of this approach, which assumes an off-target mechanism. Almost 46% of the predicted drug–target associations were disproved, but they were just as often confirmed by experimental ways. The method was used automatically at scale, without human interve ...
proe-pran - DavisPlus
... Abrupt withdrawal of propranolol may precipitate life-threatening arrhythmias, hypertension, or myocardial ischemia. Drug should be tapered over a 2-week period before discontinuation. Assess patient carefully during tapering and after medication is discontinued. Consider that patients taking propra ...
... Abrupt withdrawal of propranolol may precipitate life-threatening arrhythmias, hypertension, or myocardial ischemia. Drug should be tapered over a 2-week period before discontinuation. Assess patient carefully during tapering and after medication is discontinued. Consider that patients taking propra ...
Harvey M. Richey DO, FCCP Interim Regional Chairman Department of Medicine
... * Definitions of ratings: A: preferred; B: acceptable alternative; C: offer when A and B cannot be given; E: should never be given. When DOT is used, drugs may be given 5 days/week and the necessary number of doses adjusted accordingly. Although there are no studies that compare five with seven dail ...
... * Definitions of ratings: A: preferred; B: acceptable alternative; C: offer when A and B cannot be given; E: should never be given. When DOT is used, drugs may be given 5 days/week and the necessary number of doses adjusted accordingly. Although there are no studies that compare five with seven dail ...
Protocol for Fibromyalgia
... *2 Potential drug interactions with vitamin D3: Calcipotriene is aVitamin D analog used topically for psoriasis, and supplementing with vitamin D could cause hypercalcemia. Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if supplements are taken concurrently. ...
... *2 Potential drug interactions with vitamin D3: Calcipotriene is aVitamin D analog used topically for psoriasis, and supplementing with vitamin D could cause hypercalcemia. Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if supplements are taken concurrently. ...
curriculum vitae - The University of Sydney
... (702, JJJ, Health Report), Sydney Morning Herald, Time, New Scientist and The Australian. Expert witness and consultant in numerous legal cases. ...
... (702, JJJ, Health Report), Sydney Morning Herald, Time, New Scientist and The Australian. Expert witness and consultant in numerous legal cases. ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.