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Control Mechanisms of the GI Tract

... motility and secretions  May decrease gastric emptying (which may increase the tendency to vomit)  Side effects include dry mouth, constipation, urinary retention, and tachycardia  Examples: ...
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... • thresholds for hypertension are: • stage 1 hypertension: • surgery BP 140/90mmHg or higher • ABPM daytime average or HBPM average 135/85mmHg or higher • stage 2 hypertension: • surgery BP 160/100mmHg or higher • ABPM daytime average or HBPM average 150/95mmHg or higher • severe hypertension: • sur ...
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... GPs, as independent contractors, have the right to decline to take clinical and prescribing responsibilities for a patient on their medical list who is being treated elsewhere. However the reason for this action must be documented. In the view of the Doncaster & Bassetlaw APC, it would be the except ...
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... NSAIDs effectively quell the pain and reduce the inflammation that can occur in advanced cases, but they do nothing to halt the disease process [2]. As awareness of the GI side effects associated with NSAIDs increases, safety becomes a primary requisite in treatment. Numerous articles examining the ...
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... In regard to breastfeeding drug concentrations in breast milk that expose the infant to 0.1% of the maternal dose are regarded as safe: 10% regarded as requiring caution or avoidance. In general those patients whose disease is optimally control with DMARDs such as HCQ, sulfasalazine (SSZ) and azathi ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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