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Semprex®-D Capsules(acrivastine and pseudoephedrine
Semprex®-D Capsules(acrivastine and pseudoephedrine

... antihistamines and decongestants. Patients who are or may become pregnant should be told that this product should be used in pregnancy or during lactation only if the potential benefit justifies the potential risks to the fetus or nursing infant. Due to the risk of hypertensive crisis, patients shou ...
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... • AEs: seizures, insomnia, dizziness, HA, nausea, contraindicated if Cr Cl < 50 ml/min • Efficacy: A phase III study showed improved walking (25 ft) in 43% pts vs 9% placebo ...
IN SITU IMPLANTS FOR PARENTERAL ADMINISTRATION    Research Article
IN SITU IMPLANTS FOR PARENTERAL ADMINISTRATION    Research Article

... The  efficiency  of  any  drug  therapy  can  be  described  by  achieving  desired  concentration  of  the  drug  in  blood  or  tissue,  which  is  therapeutically effective and  non toxic  for a  prolonged period. This  goal  can  be  achieved  on  the  basis  of  proper  design  of  the  dosage  ...
PEVISONE Janssen
PEVISONE Janssen

... There are no adequate and well-controlled studies on adverse effects from the use of PEVISONE Cream in pregnant women, and no other relevant epidemiological data are available. No adverse effects on pregnancy or on the health of the foetus/ newborn child have been identified from a limited number of ...
HIGHLIGHTS OF PRESCRIBING INFORMATION Clostridium difficile
HIGHLIGHTS OF PRESCRIBING INFORMATION Clostridium difficile

... Stevens-Johnson syndrome, toxic epidermal necrolysis (some fatal) Infections and Infestations: Clostridium difficile associated diarrhea Metabolism and Nutrition Disorders: hypomagnesemia, hyponatremia ...
Respiratory System
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... Spacers : A spacer is a large-volume chamber attached to a metered-dose inhaler. Spacers decrease the deposition of drug in the mouth caused by improper inhaler technique . Spacers improve delivery of inhaled glucocorticoids and are advised for virtually all patients, especially children less than 5 ...
results of the PROXIMATE-TIMI 27 trial
results of the PROXIMATE-TIMI 27 trial

... all available clinical and safety data. There was no formal stopping rule. After enrolment of seven subjects at 0.03 mg/kg and four subjects in the 0.3 mg/kg dose tier, the Safety Committee recommended termination of recruitment in the 0.3 mg/kg dose group, and modification of the planned dose tiers ...
Sheet 25 - DENTISTRY 2012
Sheet 25 - DENTISTRY 2012

... if more than 25% usually not discovered only if they did a wisdom extraction moderate : factor VIII 1-5% , usually discovered at first year sever : factor VIII less than 1% , once you touch them they will brose and bleed and sometime its spontaneous in general these patient has a dental neglect and ...
ALBALON -A Eye Drops
ALBALON -A Eye Drops

... dispensing container to the eye or to any other surface. The use of the bottle by more than one person may spread infection. Examination of Patient If symptoms persist or worsen after a short period of treatment (approximately 2-3 days), consult a doctor. Use in Pregnancy: Animal reproduction studie ...
Amphetamines Drug Facts
Amphetamines Drug Facts

... Risk taking behaviour: amphetamines can cause over-confidence, irritability and possible aggression. It can contribute to increased violent episodes, especially in night-time economy settings. Amphetamines can also increase libido and the use of methamphetamine in the “chemsex” scene has caused incr ...
Development and Initial Evaluation of a Software
Development and Initial Evaluation of a Software

... delay in the reporting of workload results from health records. In this article, we describe the new system for measuring pharmacist workload associated with patient care, which accompanies medical record documentation. We also describe quantitatively and qualitatively the interventions performed by ...
Oral Presentation: Applications
Oral Presentation: Applications

... model. The VPC is constructed from stochastic simulations from the model therefore all model components contribute and it can help in diagnosing both structural and stochastic contributions. As the VPC is being increasingly used as a key diagnostic to illustrate model appropriateness, it is importan ...
Actelion Presentation
Actelion Presentation

... −Norez C., Noel S., Wilke M., Bijvelds M., Jorna H., Melin P., DeJonge H. and Becq F. Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the alpha-glucosidase inhibitor miglustat. FEBS Lett. 508, 2081-86; 2006. ...
Emerging Drug Trends 2014
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... ixing fentanyl with heroin isn’t new; however, the development of a synthetic fentanyl has just started to make headlines. Three overdose deaths in North Carolina have been linked to acetyl fentanyl, a designer opioid drug closely related to the prescription pain killing opioid fentanyl. Two deaths ...
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Printer Friendly pdf

... many to be of little clinical value as it was small and poorly designed – and particularly flawed as the ‘placebo’ group had previously taken Fosamax for three or more years. Although the study showed that bone mineral density continued to increase with up to 10 years of Fosamax use, it is not at al ...
transdermal approach to pain relief: present and future
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... • Studies into improved delivery systems may also make it possible for a wider range of analgesics to be delivered via a TDDS in the future ...
Emergence of Medication Assisted Therapy (MAT)
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... • Bind to cocaine or nicotine molecules and prevent them from attaching to receptors • Or, facilitate metabolism so the drug never has a chance to exert its full effects • Positive results in early pilot studies • Interesting and could be “game changing” if can develop vaccines that are safe and lon ...
Meta-Analysis of Combined Therapy with Angiotensin Receptor
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... earlier published meta-analysis indicated a benefit from combination therapy compared to ACE-inhibitor alone on readmission rates for heart failure [17], but failed to report overall readmission rates which are of particular interest based on the observed increase in adverse effects observed in the ...
Properties of GLP‐1 agonists and their use in type 2 diabetes
Properties of GLP‐1 agonists and their use in type 2 diabetes

... Experience in patients over 75 years old is limited but no recommendations for dose adjustment are made for people aged 65 years or older. Dose escalation of twice-daily exenatide from 5 to 10µg should “proceed conservatively” in patients over 70 years old. The starting dose of dulaglutide should be ...
Prescribing Information - Mallinckrodt Pharmaceuticals
Prescribing Information - Mallinckrodt Pharmaceuticals

... disorders themselves are the strongest predictors of suicide. There has been a longstanding concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-t ...
Effective October 1, 2012 - Harm Reduction Coalition
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... a state wide prescribing network in collaboration with DMHAS at community based health centers. • We contribute to and acknowledge the importance of legislative work on this issue, but also believe that to effectively fight this epidemic we can not wait for the legislative balance to tip into the ar ...
Post ECBS version ENGLISH ONLY EXPERT COMMITTEE ON
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... This appendix considers the regulatory assessment needed for dealing with situations where, for various reasons, rDNA-derived biotherapeutic products were licensed with data packages that do not follow current international regulatory standards for these biologicals – for instance, biotherapeutic pr ...
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... Fentanyl is a strong opioid, which can be used as an alternative to morphine in patients with moderate to severe pain. Due to its long half-life, it will take at least 12 – 24 hours to achieve therapeutic drug levels and so is only of benefit in patients with STABLE PAIN. ...
Canagliflozin, a New Sodium-Glucose Co
Canagliflozin, a New Sodium-Glucose Co

... drug development and clinical research in the field of diabetes.9 The SGLT2 inhibitors block the reabsorption of filtered glucose in the kidneys, leading to glucosuria—a mechanism of action that holds the potential for improvement of glycemic control, as well as the potential benefit of weight loss ...
WAUSAU HOSPITAL DRUG FORMULARY 2010
WAUSAU HOSPITAL DRUG FORMULARY 2010

... Policy #7465 contains the list of abbreviations which are not allowed for use in clinical documentation. The list contains a number of abbreviations which are considered dangerous and can be misinterpreted when written. Examples include: “U” for units, units should always be spelled out; QD for dail ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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