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Clinical condition / indication(s) for use
Clinical condition / indication(s) for use

... (GSL) and Pharmacy (P) medicines, and supply in prisons only of complete packs of the smallest available pack size of some GSL medicines to clients, by registered nurses employed by Worcestershire Health and Care NHS Trust. This policy enables a registered nurse to administer an agreed list of medic ...
Evidence for Appropriate Pain Treatment Guidelines
Evidence for Appropriate Pain Treatment Guidelines

... Long-term effectiveness • Cochrane review included 26 studies >6 monthsb • 25 studies were case series or uncontrolled long-term ...
Demographic Differences in the Misuse and Abuse of Oxycodone
Demographic Differences in the Misuse and Abuse of Oxycodone

... difficulty ambulating, nystagmus, tremors, and sleepiness. • The patient vomited and had worsening CNS depression, requiring intubation and mechanical ventilation. ...
MICROSPONGE DELIVERY SYSTEM (MDS): A UNIQUE
MICROSPONGE DELIVERY SYSTEM (MDS): A UNIQUE

... have some disadvantages like unpleasant odour, greasiness and skin irritation and fail to reach the systemic circulation in sufficient amounts in few cases. This problem is overcome by microsponge delivery system. Microsponges are tiny sponge like spherical and highly porous micro-sized particles wi ...
ADA guidelines: Implications of the United Kingdom Prospective
ADA guidelines: Implications of the United Kingdom Prospective

... ADA guidelines: Implications of the United Kingdom Prospective Diabetes Study American Diabetes Association Diabetes Care, (Supplement 1) 21:S28-32, 2001. Copyright © 2001 by the American Diabetes Association, Inc., www.diabetes.org/Diabetes or www.diabetes.org/DiabetesCare. Diabetes is a metabolic ...
Why pediatric dosing errors happen & how to avoid them
Why pediatric dosing errors happen & how to avoid them

... the length-based tape dose for epinephrine 1:1,000, not realizing that it was the endotracheal tube cardiac arrest dose instead of the IM anaphylaxis dose. In 1999 the Institutes of Medicine (IOM) published a landmark paper, “To Err is Human,” that shocked the medical community with the conclusion t ...
7: Obstetrics, Gynaecology and Urinary Tract Disorders
7: Obstetrics, Gynaecology and Urinary Tract Disorders

... The risk of cardiovascular disease (including venous thromboembolism) is higher with pills containing 50 micrograms oestrogen but there is no evidence for a difference in cardiovascular risk between 20 and 30 micrograms. The MHRA has agreed that while evidence suggests that combined oral contracepti ...


... The most widely used drugs in immune-mediated oral mucosal diseases are the topical corticosteroids. The aim of such treatment is to eliminate the symptoms, thereby allowing the patient to eat, speak and perform normal oral hygiene, since topical corticosteroids reduce or even suppress the pain and ...
Myrbetriq
Myrbetriq

... reaction information from clinical trials is useful for identifying drug-related adverse events and for approximating rates. In three, 12-week, double-blind, placebo-controlled safety and efficacy studies in patients with overactive bladder (Studies 178-CL-046, -047, and -074), MYRBETRIQ was evaluat ...
DEVELOPMENT AND VALIDATION OF SIMULTANEOUS EQUATION METHOD FOR
DEVELOPMENT AND VALIDATION OF SIMULTANEOUS EQUATION METHOD FOR

Gabapentin Fact Sheet - The Main Line Center for the Family
Gabapentin Fact Sheet - The Main Line Center for the Family

... Neurontin (gabapentin) is better known for its use as an anticonvulsant—a medication for treating epilepsy. This may present some confusion for patients, as well as their families, when they are prescribed Neurontin without a history of seizures. Although Neurontin is approved by the U.S. Food and D ...
Quinidine for Pharmacological Cardioversion of Long-lasting
Quinidine for Pharmacological Cardioversion of Long-lasting

... In the daily clinical practice, patients with longlasting (>48 hours) AF are not uncommon. In these cases, the fast activation of atrial miocardiocytes causes a complex pattern of electrophysiological alterations, called “electrical remodeling”,4 which is able to change the pharmacological sensibili ...
Ritalin and Attention Deficit Disorder: History of its Use, Effects and
Ritalin and Attention Deficit Disorder: History of its Use, Effects and

... slowly increased until an ‘effect’ is noticed. Rapport et al., however, express concern that since this ‘effect’ is judged by parents and teachers who are more likely to base their judgements on children’s social behavior, the ‘effect’ noticed may not reflect improvement in learning and impulsivity. ...
Pharmacy update What`s new in the world of pharmaceuticals?
Pharmacy update What`s new in the world of pharmaceuticals?

... • "Because of the risks of addiction, abuse and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with extended-release opioid formulations, reserve [Tradename] for use in patients for whom alternative treatment options (e.g., non-opioid analgesic ...
Headache treatment:
Headache treatment:

... ●Melatonin – Oral melatonin (10 mg) was more effective than placebo in double-blind, randomized controlled study involving 20 patients, but the response rate was relatively low (5 of 10 patients) ●Indomethacin – Although short-term indomethacin treatment is considered ineffective for cluster headach ...
Triple abx vs bactrim
Triple abx vs bactrim

... sulfonamides = bactrim/septra (tmp/smx) The most important thing you should know about antibiotics! Never expect a doctor to phone-in a prescription for an antibiotic without seeing you first. Epididymitis (inflammation of the epididymis; see the image below) is a significant cause of morbidity and ...
Margolin
Margolin

... care for themselves by contracting for their own healing, and collectives or states insisting upon caring for their members by subjecting them to procedures they define as therapeutic. Our contemporary drug problems thus cannot be understood without paying proper attention to the subtle but powerful ...
Anti-Parkinsonism drugs
Anti-Parkinsonism drugs

... a. With L-DOPA to enhance motor response b. For end-of-dose deterioration of L-DOPA , or for on-off attacks to replace L-DOPA S.Es include: nausea & vomiting; postural hypotension In high doses: delusions & hallucination (so avoided in psychotic patients); dyskinesia may also occur; ergot effects wi ...
Clinical Pharmacology of Drugs Acting on the Respiratory Organs
Clinical Pharmacology of Drugs Acting on the Respiratory Organs

... When mast cells become activated, they release a host of preformed chemical mediators which initiate an asthma attack consisting of increasing cough, wheeze, and difficulty breathing. The job of the mast cells is not complete with this act. Mast cells begin to produce a different mixture of chemical ...
Teaching Philosophy - Center for Excellence in Teaching and
Teaching Philosophy - Center for Excellence in Teaching and

... 4. Intense to the End: The end of a rotation can create a lull in learning and growth. The students can extract chart information with greater ease, they know what is expected with patient presentations during preceptor discussions, and they see the end of the rotation coming. Over the course of the ...
Exposure to Rifampicin Is Strongly Reduced in
Exposure to Rifampicin Is Strongly Reduced in

... contributing factor, we compared the pharmacokinetics of rifampicin in patients with TB, with and without DM. Methods. Seventeen adult Indonesian patients with TB and DM and 17 age- and sex-matched patients with TB and without DM were included in the study during the continuation phase of TB treatme ...
Marijuana Concentrates
Marijuana Concentrates

... (agitation and temperature) do not pose the same risks and can be done by almost anybody in a residence without danger. Next, there is a need for education about the high potency of marijuana concentrates. As mentioned, concentrates can contain up to 90 percent THC, whereas raw marijuana tops out at ...
“CRIME SCENE INVESTIGATION” AT AN ANESTHETIC COCKTAIL PARTY WITH ATRIOVENTRICULAR DISSOCIATION c
“CRIME SCENE INVESTIGATION” AT AN ANESTHETIC COCKTAIL PARTY WITH ATRIOVENTRICULAR DISSOCIATION c

... in the first place that their combination might have elicited this AV dissociation. Timing of the appearance of neostigmine shortly before the onset of the AV dissociation would also suggest that it played the major role in this act. Furthermore, due to the well known parasympathomimetic effect of n ...
INT_CAT_NGO_RUS_13012_E
INT_CAT_NGO_RUS_13012_E

... About 37.2% of injecting drug users who live in Russia are living with HIV,11 and in some regions HIV prevalence in this group reaches 75%.12 According to the official data, about 80% of HIV cases from 1987 to 2008 were related to injecting drug use.13 For 59.2% of HIV positive people identified in ...
Access OpenFDA: A Cloud Based Big Data Portal Using SAS®
Access OpenFDA: A Cloud Based Big Data Portal Using SAS®

... CROs: We have seen growth of utilizing CROs in data analysis for all phases of clinical trials, and for both small and big drug companies. Other than CRO and other data service provider, nowadays we have seen more co-developing or co-marketing efforts which join forces of 2 pharmas together to push ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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