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Inhalant Abuse - American Psychological Association
Inhalant Abuse - American Psychological Association

... The last NIDA RFA on inhalants expired in September, 2008 – Encourage NIDA to issue a new one with adequate funding Inhalants rank last in NIDA funding when sorted by drug category ...
click here
click here

... questioning, you find that he does not smoke, has not had any caffeine today, and took all of his morning medications. He has no complaints and is feeling well today. He has a history of T2DM, Dyslipidemia, COPD, allergic rhinitis, esophageal reflux, and osteoarthritis. ...
10.1 Case Report Forms
10.1 Case Report Forms

... is further complicated by the fact that only a few clinical trials have been carried out (WilderSmith et al. 1999 [1]). The best attempt to establish clear guidelines for the treatment of chronic pancreatitis is “American Gastroenterological Association Medical Position Statement: Treatment of Pain ...
Basics Pharmacology Review - Dr. Roland Halil
Basics Pharmacology Review - Dr. Roland Halil

... Clinical Pharmacist, Bruyere Academic Family Health Team March 2014 [email protected] (Partially adapted from slides by Marc Riachi, R.Ph.) ...
QUANTITATIVE ANALYSIS OF DOSE
QUANTITATIVE ANALYSIS OF DOSE

... substrate concentration factors, and Vmax have been cancelled out during derivation) suggests their general applicability (5, 6). This is in contrast to the mechanism-specific reactions (3, 5) for which the equations are far more complex. In more organized cellular or animal systems, the dose-effect ...
Reclast - Novartis Pharmaceuticals Corporation
Reclast - Novartis Pharmaceuticals Corporation

... 1500 mg elemental calcium daily in divided doses (750 mg two times a day, or 500 mg three times a day) and 800 international units vitamin D daily, particularly in the 2 weeks following Reclast administration [see Warnings and Precautions (5.2)]. ...
[Product Monograph Template
[Product Monograph Template

... symptomatic and cannot or will not use an inhaler device or would prefer not to be treated with an inhaled corticosteroid. In children, SINGULAIR® can be a treatment option after “as needed” SABAs if patients remain symptomatic and cannot appropriately use an inhaler device. SINGULAIR® can be a trea ...
Dr. Diana Barnard Dr. Ursula McVeigh
Dr. Diana Barnard Dr. Ursula McVeigh

...  For PO meds, use short acting medications for crisis, then add long acting forms for more even effect  If on IV infusion, once basal rate has started remember it takes 5 half lives to reach steady state (MS4 and HM = 10 hrs), so additional boluses will be needed in the interim ...
Mineralocorticoid receptor antagonists for heart failure with reduced
Mineralocorticoid receptor antagonists for heart failure with reduced

... 25 mg per day or placebo for 4 weeks, after which the dose of eplerenone was increased to a maximum of 50 mg per day. The major exclusion criteria and monitoring procedures are shown in Table 1. Eplerenone reduced time to death from any cause (RR 0.85, 95% CI 0.76–0.96, P ¼ 0.008) and the composite ...
1 - Robert H. Lurie Comprehensive Cancer Center
1 - Robert H. Lurie Comprehensive Cancer Center

... Other examples of common endpoints and things to consider:  Response – often a primary endpoint for phase II trials o Specify which criteria will be used (e.g. RECIST, Cheson, iwCLL2008, etc) o Specify how it will be reported:  By response category (e.g. CR/PR/SD/PD or some combination of these)  ...
ZEMPLAR® (paricalcitol)
ZEMPLAR® (paricalcitol)

... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ZEMPLAR safely and effectively. See full prescribing information for ZEMPLAR. ...
Difficult to Manage symptoms
Difficult to Manage symptoms

...  For PO meds, use short acting medications for crisis, then add long acting forms for more even effect  If on IV infusion, once basal rate has started remember it takes 5 half lives to reach steady state (MS4 and HM = 10 hrs), so additional boluses will be needed in the interim ...
Product Monograph Template - Standard
Product Monograph Template - Standard

... albicans was seen on nasal exams in 7 of 2,745 patients treated with AVAMYS® during clinical trials and was reported as an adverse event in 3 patients. When such an infection develops, it may require treatment with appropriate local therapy and discontinuation of AVAMYS®. Therefore, patients using A ...
Anesthesia and Neuromuscular Blockade - Power
Anesthesia and Neuromuscular Blockade - Power

trastuzumab - Cancer Care Ontario
trastuzumab - Cancer Care Ontario

... and patients who have had prior cardiotoxic therapy. Note: in the adjuvant trials, patients with cardiac risk factors were excluded from the trials. Exercise caution in patients with pre-existing pulmonary disease or patients with extensive pulmonary tumour involvement, as they may experience more s ...
GENERIC DRUGS: OPTIMIZING THE FUTURE
GENERIC DRUGS: OPTIMIZING THE FUTURE

... many major brand name drugs lose market exclusivity. However, the industry will face the full impact of patients shifting to lowercost generics, as well as other brands in their therapy classes, in 2012. This is due to the timing and expected competitive intensity among generic entrants. As depicted ...
INTENDED USE SUMMARY AMPHETAMINE (AMP 1,000
INTENDED USE SUMMARY AMPHETAMINE (AMP 1,000

... urine exceeds 500 ng/mL. At present, the Substance Abuse and Mental Health Services Administration (SAMHSA) does not have a recommended screening cut-off for Methylenedioxymethamphetamine positive specimens. ...
Revised: January 2016 AN. 01318/2015 SUMMARY OF PRODUCT
Revised: January 2016 AN. 01318/2015 SUMMARY OF PRODUCT

... For the treatment of bronchitis and congestive heart failure in dogs. ...
MULTIPLE UNIT EXTENDED RELEASE PELLETS OF PROPRANOLOL HYDROCHLORIDE: PREPARATION AND CHARACTERIZATION
MULTIPLE UNIT EXTENDED RELEASE PELLETS OF PROPRANOLOL HYDROCHLORIDE: PREPARATION AND CHARACTERIZATION

Jesse Sue Wageman Pharm.D. Kootenai Health Pharmacy Resident
Jesse Sue Wageman Pharm.D. Kootenai Health Pharmacy Resident

... aggression, and anxiety peak at about 1 week after the last marijuana. ...
Generic Industry
Generic Industry

... • Not allowed in EP – Not considered industrially applicable – pre2007 – Not considered patentable for moral reasons – post-2007 ...
The Řie-Tozer Model of Drug D
The Řie-Tozer Model of Drug D

... Dominguez [1], a decade prior to introduction of pharmacokinetics term by Dost in 1953 (for excellent reviews of history of pharmacokinetics see [2, 3]). Drug distribution patterns and their quantification using volume of drug distribution are among the primary considerations in drug discovery, deve ...
Preparation, characterization, and in vivo evaluation of - e
Preparation, characterization, and in vivo evaluation of - e

... among the frontrunners.7,8 The nasal route of administration is gaining popularity among pharmaceutical scientists as a potential route for achieving faster absorption and optimal bioavailability of a drug. The nasal cavity has an advantage of easy accessibility, larger surface area, porous endothel ...
PID comments (clarifax in January 2006) - Bristol
PID comments (clarifax in January 2006) - Bristol

... patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function (see DOSAGE AND ADMINISTRATION: Renal Impairment). Use in Racial/Ethnic Groups Clinical studies of ...
GUIDE FOR HERBAL PRODUCT USE BY MEXICAN AMERICANS
GUIDE FOR HERBAL PRODUCT USE BY MEXICAN AMERICANS

... In the United States, Hispanics, including Mexican Americans of both sexes and various age groups, seem to have a positive acceptance to the use of a great variety of herbal medicines for the treatment of an equally diverse array of ailments, such as cancer, diabetes, hypertension, for example. 2,3 ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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