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Trends in Retail Prices of Brand Name Prescription Drugs
Trends in Retail Prices of Brand Name Prescription Drugs

... The AARP Public Policy Institute in its Rx Price Watch series provides reports with separate analyses of the price changes for three different segments of the pharmaceutical market: brand name, generic, and specialty drug products. These three market baskets are important because a different mix of ...
Reassessing Bioavailability of Silymarin
Reassessing Bioavailability of Silymarin

... silymarin is safe at high doses (>1500 mg/day) in humans, the pharmacokinetic studies over the past three decades related to absorption, distribution, metabolism, and excretion of silymarin have revealed poor absorption, rapid metabolism, and ultimately poor oral bioavailability. For optimum silymar ...
Mechanisms and Clinical Consequences of Heart Failure
Mechanisms and Clinical Consequences of Heart Failure

... Clinical Paper. ACVIM consensus statement for the treatment of heart disease Atkins C. et al. Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart ...
Activity of Argyreia speciosa and Acorus calamus
Activity of Argyreia speciosa and Acorus calamus

... Central nervous system (CNS) is vital organ system. Hence, the drugs acting on the CNS are very important by both perspective i.e. their effects and adverse effects. Drugs acting in the central nervous system (CNS) were among the first to be discovered by primitive humans and are still the most wide ...
SUPERGEN INC (Form: DEFA14A, Received: 04/12
SUPERGEN INC (Form: DEFA14A, Received: 04/12

... officers may be deemed to be participants in the solicitation of proxies from the stockholders of the Company in connection with the proposed Transaction. Information regarding the interests of these directors and executive officers in the transaction described herein will be included in the proxy s ...
Quick guide to drugs and alcohol
Quick guide to drugs and alcohol

... The report also showed that many people underestimate the risks involved in driving while affected by drugs—particularly with illegal drugs, for which less information is available. For instance, if alcohol users and non-users are asked if driving above the blood alcohol level of .05 is dangerous, o ...
Standardizing terms for clinical pharmacogenetic test results
Standardizing terms for clinical pharmacogenetic test results

... For the first two survey rounds (surveys 1 and 2), terms that were found acceptable by at least 70% of the experts were retained for use in the next round. To improve semantic consis­ tency, terms that were retained after survey 1 were assembled into value sets, which together described the range of ...
DETERMINATION OF LEVOCETIRIZINE CONFIGURATIONAL STABILITY IN TABLETS USING  CHIRAL HPLC METHOD  Research Article 
DETERMINATION OF LEVOCETIRIZINE CONFIGURATIONAL STABILITY IN TABLETS USING  CHIRAL HPLC METHOD  Research Article 

... pharmacological  time  scale.  The  pharmaceutical  time  scale  which  concern  with  conditions  required  to  keep  the  drugs  configurationally stable during manufacturing processes and for the  whole shelf life. While pharmacological time scale is concerned with  the stability under physiologi ...
SYMBYAX®
SYMBYAX®

... In a study involving 24 healthy subjects, the mean elimination half-life of olanzapine was about 1.5 times greater in elderly subjects (>65 years of age) than in non-elderly subjects (≤ 65 years of age). The disposition of single doses of fluoxetine in healthy elderly subjects (>65 years of age) did ...
Ambien-Sonata - SWLA Center for Health Services
Ambien-Sonata - SWLA Center for Health Services

... Some medications, including over-the-counter medicines, may adversely interact with zaleplon or zolpidem, and they should not be taken concomitantly. The drug interaction may lower the blood level of the affected drug and decrease the drug’s effectiveness; or, it may elevate the blood level of the a ...
Herbal Supplements - St. Vincent Healthcare
Herbal Supplements - St. Vincent Healthcare

... herbal products, and ask your doctor or pharmacist the following questions before taking them: • Is the product safe? • Could it adversely interact with any prescription or OTC medications I am taking? • Are there any side effects? • Does it work? Has research been conducted to prove its effectivene ...
full document
full document

... 9. New active ingredient means an active ingredient contained in the composition of a drug registered for the first time for circulation in Vietnam. 10. New drug means a drug registered for the first time in Vietnam, including: a/ Drugs containing new active ingredients; b/ Drugs with a new combinat ...
NEVADA Medicaid Coverage of Medications for the Treatment of
NEVADA Medicaid Coverage of Medications for the Treatment of

... Nevada Medicaid covers Suboxone, buprenorphine/naloxone tablets, and buprenorphine tablets under FFS plans with the following limitations:  In order to approve Suboxone, buprenorphine/naloxone tablets, and buprenorphine tablets for the treatment of opioid use disorder, patients must be enrolled in, ...
PRESIDENT`S MESSAGE Patients with Pain Need Less Stigma, Not
PRESIDENT`S MESSAGE Patients with Pain Need Less Stigma, Not

... the workplace or school, and in society at large. No longer ashamed of themselves, they express profound gratitude to those who have “given them their life back” because social connectedness is at the core of a meaningful life. ...
Pharmacology and Therapeutics
Pharmacology and Therapeutics

... tablet would be appropriate for chronic intake (e.g. for arthritis) or gastric disease. Once the patent on a new drug has expired, it is possible for any drug company to manufacture and market the drug. This often means that cheaper examples (generic versions) of the same drug can be made, in which ...
highlights of prescribing information
highlights of prescribing information

... The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown). This adverse reaction is more common during long-term use of the drug, but has been observed ...
Newsletter - Willamette Valley NORML
Newsletter - Willamette Valley NORML

... a similarly high false positive rate. Of the 15,779 searches conducted after police-dog identification, no drugs were found in 11,694 cases, the Herald reported. The statistics were made public following a Parliamentary inquiry regarding the widespread use of drug dogs.Despite the high error rate, a ...
AVELOX PRODUCT INFORMATION
AVELOX PRODUCT INFORMATION

... groups. No clinically relevant interethnic differences in pharmacokinetics could be detected. Renal impairment The pharmacokinetics of moxifloxacin are not significantly changed by renal impairment (including creatinine clearance < 30 mL/min/1.73m2) and in patients on chronic dialysis i.e. haemodial ...
Topamax tablet - PIO Nas - Badan Pengawas Obat dan Makanan
Topamax tablet - PIO Nas - Badan Pengawas Obat dan Makanan

... be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. In post-marketing experience, cases of hypospadias have been reported in male infants exposed in-utero to topiramate, with or without other anticonvulsants; however, a cau ...
Prescribing - North Essex Partnership University NHS Foundation
Prescribing - North Essex Partnership University NHS Foundation

... 5.8.5. If a Consultant wishes to use an unlicensed medicine not on the approved list, a nonformulary request (Form B – see below) should be submitted to the MMG. 5.8.6. As per the GMC, before prescribing an unlicensed medicine the must prescriber must:  Be satisfied there is sufficient evidence or ...
Phencyclidine (PCP) - Center for Substance Abuse Research
Phencyclidine (PCP) - Center for Substance Abuse Research

... dependence are rare.17 A 1981 study reported that PCP users who sought treatment for PCP withdrawal experienced depression, drug craving, increased appetite, and increased need for sleep.18 Some evidence suggests that psychological dependence may develop in those who use high doses (10 mg or more) o ...
Stroke Prevention in Atrial Fibrillation
Stroke Prevention in Atrial Fibrillation

... who are performing MAZE procedures to prevent atrial fibrillation will now over-sew or exclude the left atrial appendage (with the goal to reduce stroke). There are many echocardiographic studies that question the efficacy of left atrial appendage exclusion [28] and find that certain techniques are ...
to Print Topic Help File ,
to Print Topic Help File ,

... This dosage regimen is very close to that found in part which is based on the drug - specific dosage regimen found in the USP/DI, however, the dose of Captopril for Milli based on normal adult dose and weight as given by Clark's Rule is not so successful. It gives a dose that is nearly 20 times the ...
The New Oral Anticoagulants and a New Use for Arixtra
The New Oral Anticoagulants and a New Use for Arixtra

... Retrospective Study of Medication Prescription in Oklahoma City, n=3 • 64 year old man: 14 medications daily; 31 pills • 61 year old woman: 15 medications; 39 pills • 90 year old man: 15 medications; 27 pills ...
TRIESENCE® Suspension (triamcinolone acetonide injectable
TRIESENCE® Suspension (triamcinolone acetonide injectable

... Since a number of diagnosis codes fall under the broad FDA indication of “ocular inflammatory conditions”, other diagnosis may meet the criteria for medical necessity. Document appropriate diagnosis codes and then check with the specific payor to determine if a topical corticosteroid must be adminis ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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