PSUEDOMONAS AERUGINOSA INFECTIONS IN NIGERIA Original Article
... nor affordable to majority of the populace who live below poverty line earning less than US$1.00 per day. More so, commonly available and affordable agents in routine use such as quinolones, cephalosporins, and some aminoglycosides are gradually losing their ...
... nor affordable to majority of the populace who live below poverty line earning less than US$1.00 per day. More so, commonly available and affordable agents in routine use such as quinolones, cephalosporins, and some aminoglycosides are gradually losing their ...
Methadone Maintenance Treatment (MMT)
... Facts & Consequences of Opioid Addiction in America Understanding Addiction As A Brain Disease At one time, drug addiction was viewed as a failure of willpower or a flaw of moral character. It was not recognized as a disease of the brain, in the same way that mental illnesses previously were not vie ...
... Facts & Consequences of Opioid Addiction in America Understanding Addiction As A Brain Disease At one time, drug addiction was viewed as a failure of willpower or a flaw of moral character. It was not recognized as a disease of the brain, in the same way that mental illnesses previously were not vie ...
What is Spinal Muscular Atrophy Type 4?
... Several research strategies involve manipulating the genetic instructions provided by the SMN2 gene so that more full-length SMN protein can be made. Some researchers are discovering potential drugs in what could be a considered a ‘trial and error’ approach – testing thousands of molecules to find a ...
... Several research strategies involve manipulating the genetic instructions provided by the SMN2 gene so that more full-length SMN protein can be made. Some researchers are discovering potential drugs in what could be a considered a ‘trial and error’ approach – testing thousands of molecules to find a ...
RATIO DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION
... variation, intraday variation and method repeatability studies. In interday variation, the absorbance of standard solutions of OLM (832 μg/ml) and AC (4-16 μg/ml) were measured on three consecutive days. In intraday variation the absorbances were measured three times in a day. In repeatability study ...
... variation, intraday variation and method repeatability studies. In interday variation, the absorbance of standard solutions of OLM (832 μg/ml) and AC (4-16 μg/ml) were measured on three consecutive days. In intraday variation the absorbances were measured three times in a day. In repeatability study ...
6 points each
... some patients. Theoretically, what kinds of change(s) in receptor binding would be desirable in a new drug (call it “neo-olanzapine”) that would have the same therapeutic effect and potency as olanzapine, but less dry mouth. How could the development of such a compound be pursued most effectively? S ...
... some patients. Theoretically, what kinds of change(s) in receptor binding would be desirable in a new drug (call it “neo-olanzapine”) that would have the same therapeutic effect and potency as olanzapine, but less dry mouth. How could the development of such a compound be pursued most effectively? S ...
Hypertension - National Medical Research Council
... Hypertension is a chronic disease that is a major risk factor for coronary artery disease, cardiac failure, stroke and renal failure, and is estimated to cause 4.5% of the current global disease burden. Hypertension is as prevalent in many developing countries, as in the developed world. In Singapor ...
... Hypertension is a chronic disease that is a major risk factor for coronary artery disease, cardiac failure, stroke and renal failure, and is estimated to cause 4.5% of the current global disease burden. Hypertension is as prevalent in many developing countries, as in the developed world. In Singapor ...
Recommendations of the Italian Society for Rheumatology for the
... PsA is one of the commonest inflammatory arthropathies in Italy. It is estimated that 2-3% of the Italian population is affected by psoriasis, a third of which suffers from, or will eventually develop, PsA (23-25). Recent reports suggest that PsA can be as severe as RA (26). In particular, Sokoll et ...
... PsA is one of the commonest inflammatory arthropathies in Italy. It is estimated that 2-3% of the Italian population is affected by psoriasis, a third of which suffers from, or will eventually develop, PsA (23-25). Recent reports suggest that PsA can be as severe as RA (26). In particular, Sokoll et ...
Testosterone Supplementation in Heart Failure A Meta
... SD change using Cohen D. To assess for consistency, peak V̇O2 was also normalized using Cohen D. Because no significant heterogeneity was detected across studies using I2, we did not analyze the data using a meta-regression model. The inverse variance method was used as a weighting factor to combine ...
... SD change using Cohen D. To assess for consistency, peak V̇O2 was also normalized using Cohen D. Because no significant heterogeneity was detected across studies using I2, we did not analyze the data using a meta-regression model. The inverse variance method was used as a weighting factor to combine ...
PRODUCT INFORMATION STOCRIN® (efavirenz) Tablets and Oral
... Pharmacokinetics of efavirenz in patients appear to be similar between men and women and among the racial groups studied. Geriatric Use Clinical studies of STOCRIN did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Pae ...
... Pharmacokinetics of efavirenz in patients appear to be similar between men and women and among the racial groups studied. Geriatric Use Clinical studies of STOCRIN did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Pae ...
Medical Marijuana
... (when smoked chronically), increased levels of anxiety with high dose use, and impaired cognitive ability detract from the potential benefits observed. Unfortunately, clinical trials offer mixed results regarding the effectiveness of marijuana for medicinal purposes; may indicate a lack of clear ben ...
... (when smoked chronically), increased levels of anxiety with high dose use, and impaired cognitive ability detract from the potential benefits observed. Unfortunately, clinical trials offer mixed results regarding the effectiveness of marijuana for medicinal purposes; may indicate a lack of clear ben ...
\\Appganim\Fda\Mt\Alonim\1921.doc PRAMIN INJECTION TABLETS
... recommended doses are administered or renal insufficiency is present. In patients with severe renal function impairment, the dose should be reduced by at least 60% of that normally prescribed. This is particularly important because metoclopramide-induced parkinsonism is resistant to levodopa therapy ...
... recommended doses are administered or renal insufficiency is present. In patients with severe renal function impairment, the dose should be reduced by at least 60% of that normally prescribed. This is particularly important because metoclopramide-induced parkinsonism is resistant to levodopa therapy ...
Probiotics for Gut Health - Bio-Kult
... also have a role, because it is certain that they accelerate recovery from both viral and bacterial infection. More than 25 randomised controlled trials (RCTs) have been undertaken on people with infectious diarrhoea, the majority with children. Almost every study has shown a positive benefit from p ...
... also have a role, because it is certain that they accelerate recovery from both viral and bacterial infection. More than 25 randomised controlled trials (RCTs) have been undertaken on people with infectious diarrhoea, the majority with children. Almost every study has shown a positive benefit from p ...
Pharmaceuticals: Focussing on Appropriate Utilization
... Population Health Research Data Repository to describe and explain patterns of care and profiles of illness, and to explore other factors that influence health, including income, education, employment and social status. This Repository is unique in terms of its comprehensiveness, degree of integrati ...
... Population Health Research Data Repository to describe and explain patterns of care and profiles of illness, and to explore other factors that influence health, including income, education, employment and social status. This Repository is unique in terms of its comprehensiveness, degree of integrati ...
Safety Assessment and Dose Selection for First-in
... in the United Kingdom5 has highlighted how, on rare occasions, mAbs can be highly toxic. It is for this reason that preclinical safety assessment programs for mAbs, together with their dose selection for first clinical entry, will be scrutinized more than ever by the regulatory authorities in the ye ...
... in the United Kingdom5 has highlighted how, on rare occasions, mAbs can be highly toxic. It is for this reason that preclinical safety assessment programs for mAbs, together with their dose selection for first clinical entry, will be scrutinized more than ever by the regulatory authorities in the ye ...
check these out from a debate on legalizing
... "I was up to seventeen different pills, three times a day and I was pretty incapacitated because of the side effects when my application [to the Compassionate IND program for medical marijuana] was finally approved and my doctor received my first shipment of medical marijuana from the federal govern ...
... "I was up to seventeen different pills, three times a day and I was pretty incapacitated because of the side effects when my application [to the Compassionate IND program for medical marijuana] was finally approved and my doctor received my first shipment of medical marijuana from the federal govern ...
Cachexia is the result of a complex array of metabolic... results in loss of appetite, tissue wasting, muscle and visceral...
... Hospital UCLA studied 38 patients with advanced cancer and weight loss. Patients were placed in a carefully-controlled study to evaluate the influence of hydrazine sulfate on carbohydrate metabolism. They were given a standard dose of 60 milligram capsules three times a day for 30 days. Glucose tole ...
... Hospital UCLA studied 38 patients with advanced cancer and weight loss. Patients were placed in a carefully-controlled study to evaluate the influence of hydrazine sulfate on carbohydrate metabolism. They were given a standard dose of 60 milligram capsules three times a day for 30 days. Glucose tole ...
Edluar sublingual tablet ENG SmPC
... agents with a short duration of action, withdrawal phenomena can become manifest within the dosage interval, especially when the dosage is high. As the risk of withdrawal symptoms/rebound phenomena are more likely to develop after abrupt discontinuation of treatment, it is recommended to decrease th ...
... agents with a short duration of action, withdrawal phenomena can become manifest within the dosage interval, especially when the dosage is high. As the risk of withdrawal symptoms/rebound phenomena are more likely to develop after abrupt discontinuation of treatment, it is recommended to decrease th ...
FULL PRESCRIBING INFORMATION 1 INDICATIONS
... bind to cytosolic receptor protein. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization and inflammatory processes. However, the significance of these findings with regard to the mechanism of action of adapalene ...
... bind to cytosolic receptor protein. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization and inflammatory processes. However, the significance of these findings with regard to the mechanism of action of adapalene ...
Vytorin - Merck.com
... Due to the increased risk of myopathy, including rhabdomyolysis, associated with the 10/80-mg dose of VYTORIN, patients unable to achieve their LDL-C goal utilizing the 10/40-mg dose of VYTORIN should not be titrated to the 10/80-mg dose, but should be placed on alternative LDL-C-lowering treatment( ...
... Due to the increased risk of myopathy, including rhabdomyolysis, associated with the 10/80-mg dose of VYTORIN, patients unable to achieve their LDL-C goal utilizing the 10/40-mg dose of VYTORIN should not be titrated to the 10/80-mg dose, but should be placed on alternative LDL-C-lowering treatment( ...
Use of low-dose pregabalin in patients undergoing - STOP-Bang
... scores were analysed with the Kruskal–Wallis test. If there was a significant difference among the groups, individual groups were compared in a pairwise manner using a Mann– Whitney U-test. Patient data, analgesic consumption, sideeffects, and recovery scores were analysed with analysis of variance. ...
... scores were analysed with the Kruskal–Wallis test. If there was a significant difference among the groups, individual groups were compared in a pairwise manner using a Mann– Whitney U-test. Patient data, analgesic consumption, sideeffects, and recovery scores were analysed with analysis of variance. ...
cdph/oa/adap - Magellan Rx
... Refills may be obtained after 80 percent of the previously dispensed days’ supply has been used; however, there is an annual maximum of 13 fills per prescription. ...
... Refills may be obtained after 80 percent of the previously dispensed days’ supply has been used; however, there is an annual maximum of 13 fills per prescription. ...
Product Monograph
... Geriatrics ( 65 years of age): The safety and efficacy of EPIVAL® in elderly patients with epilepsy or mania has not been evaluated in clinical trials. Caution should thus be exercised in dose selection for an elderly patient, recognizing the more frequent hepatic and renal dysfunctions, and limite ...
... Geriatrics ( 65 years of age): The safety and efficacy of EPIVAL® in elderly patients with epilepsy or mania has not been evaluated in clinical trials. Caution should thus be exercised in dose selection for an elderly patient, recognizing the more frequent hepatic and renal dysfunctions, and limite ...
The Management of Atrial Fibrillation in the ICU
... The current delivered to the heart is determined by both the energy chosen (J) and the transthoracic impedance [31,32]. The use of bare paddles without a couplant (gel/cream) results in very high transthoracic impedance [31,32]. Impedance may be reduced by strong pressure on the paddles, anteroposte ...
... The current delivered to the heart is determined by both the energy chosen (J) and the transthoracic impedance [31,32]. The use of bare paddles without a couplant (gel/cream) results in very high transthoracic impedance [31,32]. Impedance may be reduced by strong pressure on the paddles, anteroposte ...
Anti platelet Agents
... safety of antiplatelet therapy is provided by the collaborative meta-analysis of 287 secondary prevention trials, prepared by the Antithrombotic Trialists’ (ATT) Collaboration2 (available online at www.bmj.com). The purpose of the present guidelines is to integrate a mechanistic understanding as to ...
... safety of antiplatelet therapy is provided by the collaborative meta-analysis of 287 secondary prevention trials, prepared by the Antithrombotic Trialists’ (ATT) Collaboration2 (available online at www.bmj.com). The purpose of the present guidelines is to integrate a mechanistic understanding as to ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.