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Immune correlates of HIV-associated cryptococcal meningitis
Immune correlates of HIV-associated cryptococcal meningitis

... Cryptococcosis occurs almost exclusively in individuals with impaired cell-mediated immunity. The vast majority of cases worldwide are associated with advanced HIV infection, illustrating the vital importance of CD4 T cells in the human host response [15, 16]. Other risk factors include solid organ ...
human monoclonal antibody technology.
human monoclonal antibody technology.

... the IgM isotype and they have a low affinity for the antigen. Such characteristics are typical of antibodies derived from a naive or primary immune repertoire. IgGproducing clones have been reported recently to occur in some cases (Boerner et al., 1991), but the general applicability of this in vitr ...
nail and nail-bed disorders
nail and nail-bed disorders

...  Bacterial infection/inflammation of soft tissue around the nail or claw (paronychia) or fungal infection of the nail or claw (onychomycosis)—treatment may be prolonged and response may be influenced by underlying factors that decrease the immune response (immunosuppressive factors)  Fungal infect ...
LEUCOCYTES BENIGN DISORDERS
LEUCOCYTES BENIGN DISORDERS

...  Chronic infection (TB, typhoid fever, infective endocarditis)  Recovery from acute infection ...
Document
Document

... in line with international recommendations.  The determination of priorities for contact investigation is based on the likelihood that a contact: 1) has undiagnosed TB; 2) is at high risk of developing TB if infected; 3) is at risk of having severe TB if the disease develops; and 4) is at high risk ...
Meningitis - Boston Public Health Commission
Meningitis - Boston Public Health Commission

... certain medical problems, some medications, or different types of infections. The severity of the disease and the treatment depend on the cause of infection.  Non–infectious meningitis can be caused by cancers, head injury, brain surgery, and other medical problems. Certain drugs can also cause men ...
conjunctiva anatomy and physiology
conjunctiva anatomy and physiology

Hepatitis B virus genotype in Iranian patients with hepatocellular
Hepatitis B virus genotype in Iranian patients with hepatocellular

... hepatitis B surface antigen (HBsAg) in Iran to be between 2.5% and 7.2%.4 A more recent nationwide study showed that the prevalence of HBsAg ranges from 1.7% to over 5% in the different provinces.5 Although the true prevalence of HCC in Iran is unknown, it is not an uncommon malignancy; 80% of HCC c ...
Infectious calf diarrhea
Infectious calf diarrhea

... perfringens is normally found in the intestine of cattle and can survive for months in the soil. Overeating or sudden change of diet tend to produce indigestion, which slows gut movement, providing the sugars, proteins and lack of oxygen for rapid growth of Clostridium perfringens. Wet conditions al ...
A review of the  infectious diseases of African wild ruminants
A review of the infectious diseases of African wild ruminants

... been eradicated in 1974, it was reintroduced in 1980 and 1983 and caused the death of an estimated one million cattle and mortalities in wildlife including buffaloes, warthogs, waterbuck and bushbuck (Shanthikumar, Malachi & Mayiyagbe 1985; Shanthikumar & Atilola 1990). Currently there are only four ...
Addressing Parents` Concerns: Do Multiple Vaccines
Addressing Parents` Concerns: Do Multiple Vaccines

Document
Document

... has it on their skin, or you could get it by touching objects that have the bacteria on them. – MRSA is carried, or "colonized," by about 1% of the population, although most of them aren't infected. – Infections are most common among people who have weak immune systems and are living in hospitals, n ...
Antimicrobial dressings
Antimicrobial dressings

... reassessment to exclude contributing causes other than infection and may indicate the need for an alternative approach or the addition of systemic therapy. For wounds that improve, antimicrobial dressings should be continued for 14–21 days14, at which time the need for further antimicrobial therapy ...
hepatitis c - AbbVie | Canada
hepatitis c - AbbVie | Canada

... Actually, hepatitis C CAN be cured. Hepatitis C is the only chronic viral infectious disease that may be “virologically cured”. “Virologic cure” means sustained virologic response (the absence of detectable virus in a person’s bloodstream) 24 weeks after the end of treatment (SVR24). However, recent ...
coccidioidomycosis (valley fever): a re
coccidioidomycosis (valley fever): a re

... 10. The Th1 cytokine profile correlates with resistance to Coccidioides infection while the Th2 cytokine profile correlates with susceptibility. Interleukin-6 plays a key role in acute inflammation and in the differentiation of T lymphocytes into cells that secrete interleukin-17. Persistent activat ...
recommended wording for national laboratories to report
recommended wording for national laboratories to report

... HBsAg positivity for 6 months or more is consistent with CHRONIC hepatitis B infection. If CHRONIC hepatitis B infection: recommend testing for HBeAg, anti-HBe, HBV viral load, HCV, HDV, HIV, assessment of liver function including ultrasound and specialist referral. For further information see www.h ...
docx - Center for Inference and Dynamics of Infectious Diseases
docx - Center for Inference and Dynamics of Infectious Diseases

... member(s) of an enrolled cluster who were detected via surveillance (i.e., the reason for the enrollment of the cluster into the study) as the index case(s). In humans, the complex nature of the process defining whether an infected/symptomatic individual will be detected by surveillance system can l ...
Case 6:”Kutis Porcelana”
Case 6:”Kutis Porcelana”

... within 24 hrs of the rash results in diminution and duration of skin lesions. Should be considered in adolescents and adults with varicella VZIG should be given with 96 hrs of exposure to susceptible high risk patients for severe or complicated Varicella ...
What is hepatitis B?
What is hepatitis B?

... Most people do not die from it. There are cases where hepatitis B can cause liver damage (cirrhosis [sir-O-sis]) that does not go away. Hepatitis B can also cause liver cancer, which may lead to death. Good medical care can make your risk less for these. ...
viral hepatitis in health service workers in the province of wielkopolska
viral hepatitis in health service workers in the province of wielkopolska

Is AIDS really caused by a virus?
Is AIDS really caused by a virus?

Immunohistochemical analysis of infectious hematopoietic necrosis
Immunohistochemical analysis of infectious hematopoietic necrosis

... Proteins. The nucleocapsid protein is the most abundant and highly conserved protein of IHNV (Gilmore and Leong 1988). The N protein binds to the ssRNA genome and provides stability and structure. It is necessary for encapsidation and infectivity. Because of the highly conserved, abundant nature of ...
Epidemiologic, clinical and laboratory features of scrub
Epidemiologic, clinical and laboratory features of scrub

... the IFA test8 and the indirect immunoperoxidase test using yolk sac-propagated or cell culture-derived O. tsutsugamushi antigens.26 The specificity and sensitivity of the IFA test are 0.96 and 0.54, respectively, at the cutoff titers used in our study.8 Because of a limited supply of O. tsutsugamush ...
Seasonality, variation in species prevalence, and localized disease
Seasonality, variation in species prevalence, and localized disease

... (FV3) cause most of the infections in amphibians in the United States (Chinchar et al. 2009). Mortality in pond-dwelling larval amphibians, where most virus-associated mortality is observed, can occur in excess of 90% during die-off events (Green & Converse 2005). In the Southwestern United States, ...
New Born Calf Serum - HiMedia Laboratories
New Born Calf Serum - HiMedia Laboratories

... New Born Calf Serum is processed from calves that are 3-10 days old. It contains higher levels of proteins and immunoglobulins and less growth factors than Fetal Bovine Serum (FBS). It is a cost effective alternative to FBS and can be used for culturing most mammalian cell lines. It has proved to be ...
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Human cytomegalovirus



Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within Herpesviridae, HCMV belongs to the Betaherpesvirinae subfamily, which also includes cytomegaloviruses from other mammals.Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly other malignancies such as prostate cancer.HCMV is found throughout all geographic locations and socioeconomic groups, and infects between 60% and 70% of adults in industrialized countries and almost 100% in emerging countries.Of all herpes viruses, HCMV harbors the most genes dedicated to altering (evading) innate and adaptive immunity in the host and represents a life-long burden of antigenic T cell surveillance and immune dysfunction.Commonly it is indicated by the presence of antibodies in the general population. Seroprevalence is age-dependent: 58.9% of individuals aged 6 and older are infected with CMV while 90.8% of individuals aged 80 and older are positive for HCMV. HCMV is also the virus most frequently transmitted to a developing fetus.HCMV infection is more widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. Congenital HCMV is the leading infectious cause of deafness, learning disabilities, and intellectual disability in childrenCMV also ""seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality.""
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