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MMWR in Review: Mouse infestation likely source of lymphocytic
MMWR in Review: Mouse infestation likely source of lymphocytic

... Mouse fecal pellets from the patient's home tested positive for LCMV by polymerase chain reaction. The family was referred for integrated pest management services, and no further household cases were reported. Comment LCMV is a zoonotic arenavirus transmitted to humans by exposure to urine, saliva o ...
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... study who had plasma and PBMC specimen collected upon entrance into the study that specimens had been stored appropriately and were available for testing. The HlV -1 RNA SUBstudy meluded 17 random selected patients from the drug study who had plasma specimen collected on the entrance into the study ...
What are Healthcare Associated Infections?
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... 1. The importance and general principles of infection prevention and control 2. The nature of Healthcare Associated Infection (HCAI) 3. Factors that may increase susceptibility to infection 4. Individual responsibility to infection prevention & control 5. Where to find information, including legisla ...
Rotavirus
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... C. Shigella produces a N-glycosidase that has a specificity for 28S ribosomal RNA and upon this action stops protein synthesis of the host cell D. Vibrio cholerae ADP-ribosylates G-proteins and thereby activates an adenylate cyclase which indirectly affects the efflux of water 4. Each of the followi ...
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Herpes B Virus Information for Labs Handling Non

... Labs handling tissues, organs or cells from macaque species should be familiar with the risk of B virus infection, exposure prevention measures, and special post-exposure first aid measures. B virus infection is caused by the zoonotic agent Macacine herpesvirus (formerly Cercopithecine herpesvirus 1 ...
Sexually Transmitted Infections
Sexually Transmitted Infections

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Chapter 15 - Waukee Community School District Blogs
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Diseases - TWO Academies
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HIV Vaccine Immunogen Design
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... and has the shape of a truncated icosahedron, which resembles a football ball. These molecules decorated with specific carbohydrates (sugars) present affinity by the receptor used as an entry point to infect the cell and act blocking it, thus inhibiting the infection. Researchers employed an artific ...
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Serology Review
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...  Serious for patients with defective immune systems  In babies may cause life threatening illness  Patients with deficient immune systems  AIDS patients  Transplant patients  Detection of CMV antigen in cells using IFA  ELISA to detect antibody to CMV  Other  fluorescence assays,  indirect ...
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...  Be alert for sharp objects, broken glassware, used syringes in trash  Do not pick up broken glass - use brush or broom and ...
The Role of Matrix Metalloproteases in Respiratory Syncytial
The Role of Matrix Metalloproteases in Respiratory Syncytial

... RSV particles is essential for their infectivity, as it mediates the the fusion of the viral envelope and the cell membrane to the target cell thereby allowing the viral nucleocapsid to enter the target cell cytoplasm. At the surface of the infected cell, it also induces fusion between the cell memb ...
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Human cytomegalovirus



Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within Herpesviridae, HCMV belongs to the Betaherpesvirinae subfamily, which also includes cytomegaloviruses from other mammals.Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly other malignancies such as prostate cancer.HCMV is found throughout all geographic locations and socioeconomic groups, and infects between 60% and 70% of adults in industrialized countries and almost 100% in emerging countries.Of all herpes viruses, HCMV harbors the most genes dedicated to altering (evading) innate and adaptive immunity in the host and represents a life-long burden of antigenic T cell surveillance and immune dysfunction.Commonly it is indicated by the presence of antibodies in the general population. Seroprevalence is age-dependent: 58.9% of individuals aged 6 and older are infected with CMV while 90.8% of individuals aged 80 and older are positive for HCMV. HCMV is also the virus most frequently transmitted to a developing fetus.HCMV infection is more widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. Congenital HCMV is the leading infectious cause of deafness, learning disabilities, and intellectual disability in childrenCMV also ""seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality.""
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