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IgG2 subclass isotype antibody and intrauterine
IgG2 subclass isotype antibody and intrauterine

... causative agents of intrauterine infections possess capsular and polysaccharide antigens which can elicit IgG2 response. But this response cannot be passively transported to the foetus in expecting mothers due to the inability of IgG2 to pass across placenta. This may be the reason for the deficit i ...
hepatitis b
hepatitis b

... the hepatitis B virus. It can range in severity from a mild illness lasting a few weeks to a serious, lifelong illness. Hepatitis B can be either “acute” or “chronic”. Acute hepatitis B virus infection is a short-term illness that occurs within the first 6 months after someone is exposed to the hepa ...
The Spotty Book - Livewell South West
The Spotty Book - Livewell South West

... This is because their immune systems are less developed and they don’t receive as much natural immunity from their mothers. It’s especially important that premature babies get their vaccines on time, from two months after birth, no matter how premature they are. It may seem very early to give a vacc ...
FAQs about Clostridium difficile (PDF: 180 KB/1 page)
FAQs about Clostridium difficile (PDF: 180 KB/1 page)

... The elderly and people with certain medical problems have the greatest chance of getting C. diff. C. diff spores can live outside the human body for a very long time and may be found on things in the environment such as bed linens, bed rails, bathroom fixtures, and medical equipment. C. diff infecti ...
Recommendations on the Management of HIV Infection in Infants
Recommendations on the Management of HIV Infection in Infants

... decrease in CD4+ lymphocyte counts in the first year of life signifies rapid progression of HIV disease and indicates the immediate need for highly active antiretroviral therapy (HAART). The immunological classification system for HIV infection in children is in Table 4. (b) HIV virus load Quantific ...
M - Control Influenza Main
M - Control Influenza Main

... aerosols (which rise by thermal mixing) will be exposed. ...
Smallpox Fact Sheet
Smallpox Fact Sheet

... Yes, however the vaccine can have serious side effects so it is not available for the general public. Routine vaccination in the U.S. against smallpox stopped in 1972 after the disease was eradicated. At this time the vaccine is only recommended for people who have a high risk of exposure to the vir ...
One Defective Interfering Particle per Cell Prevents Influenza Virus
One Defective Interfering Particle per Cell Prevents Influenza Virus

... The observation that the particle :infectivity ratio of influenza virus increases on passage at high m.o.i., by several orders of magnitude, while the overall production of virus particles remains constant (von Magnus, 1951) led to the recognition of what is now called defective interfering (DI) vir ...
communicable disease exclusion guidelines
communicable disease exclusion guidelines

... preventing MODERATE to SEVERE DISEASE, but only 70% to 85% effective in preventing MILD to MODERATE disease. Cases of varicella may occur in some vaccinated persons following exposure to wild-type virus. This is called breakthrough infection. Breakthrough infection is varicella to wild-type varicell ...
The metaphor that viruses are living is alive and well, but it is no
The metaphor that viruses are living is alive and well, but it is no

Heparan sulphate mediates swine vesicular disease virus
Heparan sulphate mediates swine vesicular disease virus

... the enterovirus genus that causes an emerging disease of pigs (SVD) whose symptoms are similar to those caused by FMDV (Nardelli et al., 1968). The comparison of the complete genome sequences of SVDV and coxsackie B5 viruses (CVB5) reveals a close relationship between these two viruses (Zhang et al. ...
Zika Medical Information
Zika Medical Information

... Pregnancy related Complications ...
Integrating Viral Hepatitis into Client
Integrating Viral Hepatitis into Client

... Primarily transmitted via fecal-oral route and rarely through blood exposure Highly infectious and stable in environment for months Most common transmission through close personal contact with an infected person Vaccine is available to prevent infection ...
Hepatitis B FAQ document - National Institute for Communicable
Hepatitis B FAQ document - National Institute for Communicable

... and fluid intake, most persons recover spontaneously. Occasionally some persons may need to be hospitalized. Chronic hepatitis B is treatable - persons with chronic infection should consult a doctor with experience treating HBV. Persons with chronic HBV should be evaluated for treatment eligibility ...
Isolation Policy - Royal Cornwall Hospitals NHS Trust
Isolation Policy - Royal Cornwall Hospitals NHS Trust

... Generally these patients are most at risk from their own resident flora (endogenous infection) but must also be protected from the risk of cross infection (exogenous infection). As most infections are endogenous, there should be an emphasis on patient education regarding hand washing and basic hygie ...
Factors that make an infectious disease outbreak
Factors that make an infectious disease outbreak

... he global spread of severe acute respiratory syndrome (SARS) in early 2003 caused at least 800 deaths and substantial morbidity and had a significant economic cost for the worse affected countries (1–4). Despite rapid early spread, the epidemic eventually was contained, reflecting in part a highly e ...
Mumps Clinical Signs and Symptoms
Mumps Clinical Signs and Symptoms

... Clinical Signs and Symptoms ...
http://ecdc.europa.eu/en/publications/Publications/Zika-virus-French-Polynesia-rapid-risk-assessment.pdf
http://ecdc.europa.eu/en/publications/Publications/Zika-virus-French-Polynesia-rapid-risk-assessment.pdf

... Laboratory diagnosis Zika diagnosis is primarily based on detection of viral RNA from clinical specimens. The viraemic period has not been established but is believed to be short, allowing for direct virus detection during the first 3–5 days after onset of symptoms [1,14]. Specific assays have been ...
Influenza - UNM Hospitalist Group / FrontPage
Influenza - UNM Hospitalist Group / FrontPage

Understanding Viruses, Third Edition SEE WHAT`S NEW TO THE
Understanding Viruses, Third Edition SEE WHAT`S NEW TO THE

... This Transition Guide outlines many of the changes and new content in the Third Edition. Use this guide for an easy transition to the new edition. From Adenovirus to Zika virus, the Third Edition of best-selling Understanding Viruses provides a strong, comprehensive introduction to human viral disea ...
Cleaning and Disinfection Protocol
Cleaning and Disinfection Protocol

... This document has been developed in accordance with current applicable infection control and  regulatory guidelines.  It is intended for use as a guideline only.  At no time should this document replace  existing documents established by the facility unless written permission has been obtained from  ...
A Study of Risk Factors for Acquisition of Epstein
A Study of Risk Factors for Acquisition of Epstein

Zika Information for - BC Centre for Disease Control
Zika Information for - BC Centre for Disease Control

... Laboratory Testing (see Table 1 for Laboratory Testing Guidelines) Zika viral RNA may be present in a patient’s blood for approximately 7 days after symptom onset and has been shown to persist in urine for greater than 10 days. If symptoms have resolved or the patient is asymptomatic, diagnosis is b ...
Fact Sheet Norovirus in Food Handlers Fact Sheet
Fact Sheet Norovirus in Food Handlers Fact Sheet

Vaccine discovery and translation of new vaccine technology
Vaccine discovery and translation of new vaccine technology

... vaccine antigens in silico (reviewed by Vivona et al, 2008), usually surface-exposed proteins, ranking them based on a variety of factors and finally testing their vaccine potential in animal disease models. This approach was pioneered by Rino Rappuoli and colleagues at Novartis for meningococcal va ...
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Human cytomegalovirus



Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within Herpesviridae, HCMV belongs to the Betaherpesvirinae subfamily, which also includes cytomegaloviruses from other mammals.Although they may be found throughout the body, HCMV infections are frequently associated with the salivary glands. HCMV infection is typically unnoticed in healthy people, but can be life-threatening for the immunocompromised, such as HIV-infected persons, organ transplant recipients, or newborn infants. After infection, HCMV remains latent within the body throughout life and can be reactivated at any time. Eventually, it may cause mucoepidermoid carcinoma and possibly other malignancies such as prostate cancer.HCMV is found throughout all geographic locations and socioeconomic groups, and infects between 60% and 70% of adults in industrialized countries and almost 100% in emerging countries.Of all herpes viruses, HCMV harbors the most genes dedicated to altering (evading) innate and adaptive immunity in the host and represents a life-long burden of antigenic T cell surveillance and immune dysfunction.Commonly it is indicated by the presence of antibodies in the general population. Seroprevalence is age-dependent: 58.9% of individuals aged 6 and older are infected with CMV while 90.8% of individuals aged 80 and older are positive for HCMV. HCMV is also the virus most frequently transmitted to a developing fetus.HCMV infection is more widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. Congenital HCMV is the leading infectious cause of deafness, learning disabilities, and intellectual disability in childrenCMV also ""seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality.""
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