Targeting protein synthesis in cancer cells (PDF Available)
... Another mechanism which can account for the inefficacy of mTOR inhibitors in pancreatic cancer has been recently highlighted. Although 4E-BP1 is highly expressed in the exocrine pancreas, we have actually found that a primary resistance to mTOR inhibitors exists in pancreatic cancer cells due to the ...
... Another mechanism which can account for the inefficacy of mTOR inhibitors in pancreatic cancer has been recently highlighted. Although 4E-BP1 is highly expressed in the exocrine pancreas, we have actually found that a primary resistance to mTOR inhibitors exists in pancreatic cancer cells due to the ...
PROJECT PROPOSAL for applicants for Ph.D. fellowships
... Plant cells have noticeable developmental plasticity. One of the most interesting examples of this plasticity is somatic embryogenesis during which differentiated somatic plant cells regain totipotency and develop into embryos and after plants. In order to be able to initiate the embryogenic program ...
... Plant cells have noticeable developmental plasticity. One of the most interesting examples of this plasticity is somatic embryogenesis during which differentiated somatic plant cells regain totipotency and develop into embryos and after plants. In order to be able to initiate the embryogenic program ...
The Euglena - Hamilton Local Schools
... Euglena are unicellular organisms classified into the Kingdom Protista, and the Phylum Euglenophyta. All euglena have chloroplasts and can make their own food by photosynthesis. They are not completely autotrophic though, euglena can also absorb food from their environment. Euglena usually live in q ...
... Euglena are unicellular organisms classified into the Kingdom Protista, and the Phylum Euglenophyta. All euglena have chloroplasts and can make their own food by photosynthesis. They are not completely autotrophic though, euglena can also absorb food from their environment. Euglena usually live in q ...
Cell Membrane
... Vesicle-mediated transport Vesicles and vacuoles that fuse with the cell membrane may be utilized to release or transport chemicals out of the cell or to allow them to enter a cell. Exocytosis is the term applied when transport is out of the cell. ...
... Vesicle-mediated transport Vesicles and vacuoles that fuse with the cell membrane may be utilized to release or transport chemicals out of the cell or to allow them to enter a cell. Exocytosis is the term applied when transport is out of the cell. ...
Cell walls
... The carboxyl groups of some of the galacturonosyl residues are methyl esterified. Esterification is more than 75% => pectins (果膠質) Esterification is less than 75% => pectinic acid (果 膠質酸) No esterification => pectate (果膠酸) ...
... The carboxyl groups of some of the galacturonosyl residues are methyl esterified. Esterification is more than 75% => pectins (果膠質) Esterification is less than 75% => pectinic acid (果 膠質酸) No esterification => pectate (果膠酸) ...
Cell Membrane - WasmundScience
... Vesicle-mediated transport Vesicles and vacuoles that fuse with the cell membrane may be utilized to release or transport chemicals out of the cell or to allow them to enter a cell. Exocytosis is the term applied when transport is out of the cell. ...
... Vesicle-mediated transport Vesicles and vacuoles that fuse with the cell membrane may be utilized to release or transport chemicals out of the cell or to allow them to enter a cell. Exocytosis is the term applied when transport is out of the cell. ...
Short-range control of cell differentiation in the Arabidopsis root
... observed in wild-type roots (Fig. 1f, arrow; Table 1). The QC thus controls the differentiation state of columella initials in the absence of cell division. These results show that columella cell division is not a prerequisite for inhibition of differentiation (Fig. 2, model 2). To determine whether ...
... observed in wild-type roots (Fig. 1f, arrow; Table 1). The QC thus controls the differentiation state of columella initials in the absence of cell division. These results show that columella cell division is not a prerequisite for inhibition of differentiation (Fig. 2, model 2). To determine whether ...
Algebra 1 - Edublogs
... _______________. A solution where molecules are evenly distributed is at _________________________. 3 Types of Passive Transport 1. Diffusion is the movement of _________________ from ______ to ______ concentration without ______________. Molecules that are ___________ or ___________ can diffuse acr ...
... _______________. A solution where molecules are evenly distributed is at _________________________. 3 Types of Passive Transport 1. Diffusion is the movement of _________________ from ______ to ______ concentration without ______________. Molecules that are ___________ or ___________ can diffuse acr ...
as a PDF
... et al., 2002). More-recent studies using a similar ectopic oversimultaneously operated by a group of cells (Engelberg-Kulka expression system (Amitai et al., 2004) showed that MazE can and Hazan, 2003). Supporting evidence for the view that indeed resuscitate E. coli cells within six hours of MazF b ...
... et al., 2002). More-recent studies using a similar ectopic oversimultaneously operated by a group of cells (Engelberg-Kulka expression system (Amitai et al., 2004) showed that MazE can and Hazan, 2003). Supporting evidence for the view that indeed resuscitate E. coli cells within six hours of MazF b ...
Minute Total Protein Extraction Kit (For Animal Cultured Cells and
... 1. Prior to protein extraction pre-chill native cell lysis buffer (SN-002) and protein extraction filter cartridge with collection tube on ice. 2. Harvest the cell by low speed centrifugation. Wash the cell in cold PBS once and pellet the cells by centrifugation at 3000 rpm for 2-3 min. Aspirate the ...
... 1. Prior to protein extraction pre-chill native cell lysis buffer (SN-002) and protein extraction filter cartridge with collection tube on ice. 2. Harvest the cell by low speed centrifugation. Wash the cell in cold PBS once and pellet the cells by centrifugation at 3000 rpm for 2-3 min. Aspirate the ...
science - Amazon Web Services
... cells are formed. After fertilization, embryos begin to develop. These embryos grow into adult ferns. Many types of fungi also reproduce by spores. The spores in fungi function somewhat differently than they do in plants. Spores are released into the air by the parent fungus. When they settle onto s ...
... cells are formed. After fertilization, embryos begin to develop. These embryos grow into adult ferns. Many types of fungi also reproduce by spores. The spores in fungi function somewhat differently than they do in plants. Spores are released into the air by the parent fungus. When they settle onto s ...
Document
... A fuel cell is a device that generates electricity without combustion. In a fuel cell, chemical energy is converted directly into electrical energy. Fuel cell is similar to battery. There are two electrodes in a fuel cell. These electrodes are separated by an electrolyte. Fuel is supplied to the ano ...
... A fuel cell is a device that generates electricity without combustion. In a fuel cell, chemical energy is converted directly into electrical energy. Fuel cell is similar to battery. There are two electrodes in a fuel cell. These electrodes are separated by an electrolyte. Fuel is supplied to the ano ...
E - U of L Class Index
... want to obtain useful/measurable electrochemical energy, we need to separate the two half-reactions into compartments called half-cells. This prevents the zinc from reacting with the Cu2+ directly – instead the electrons must travel from one half-cell to the other via connected electrodes. Meanwhile ...
... want to obtain useful/measurable electrochemical energy, we need to separate the two half-reactions into compartments called half-cells. This prevents the zinc from reacting with the Cu2+ directly – instead the electrons must travel from one half-cell to the other via connected electrodes. Meanwhile ...
Laura`s Poster
... Miscanthus is a woody, rhizomatous perennial tall grass, originating from Asia. This fast growing plant exhibits high water efficiency and the ability to grow on low quality lands, qualities which make it an ideal crop for biofuels. However, converting lignocellulosic material into ethanol and other ...
... Miscanthus is a woody, rhizomatous perennial tall grass, originating from Asia. This fast growing plant exhibits high water efficiency and the ability to grow on low quality lands, qualities which make it an ideal crop for biofuels. However, converting lignocellulosic material into ethanol and other ...
Technical Tip - Cytoskeleton, Inc.
... A4. SiR probes are excited by and emit light in the near infrared/far red spectral range, thus avoiding the use of shorter wavelengths such as blue and green light that typically autofluoresce, causing higher background signals. SiR-coupled probes possess two physical states: 1. a non-fluorescent, c ...
... A4. SiR probes are excited by and emit light in the near infrared/far red spectral range, thus avoiding the use of shorter wavelengths such as blue and green light that typically autofluoresce, causing higher background signals. SiR-coupled probes possess two physical states: 1. a non-fluorescent, c ...
Lecture 1
... Microbiology, traditionally, is the study of "small life forms", those that are not easily observable with the unaided eye. These organisms include viruses, bacteria, protists, and even some fungi and animals. Many of these organisms are pathogenic, so a large portion of the course will deal with th ...
... Microbiology, traditionally, is the study of "small life forms", those that are not easily observable with the unaided eye. These organisms include viruses, bacteria, protists, and even some fungi and animals. Many of these organisms are pathogenic, so a large portion of the course will deal with th ...
The mechanism of antibiotics
... • Bacteriostatic: bacterium is unable to produce any proteins correctly, leading to a halt in growth and eventually cell death ...
... • Bacteriostatic: bacterium is unable to produce any proteins correctly, leading to a halt in growth and eventually cell death ...
PDF
... treatment and was almost twice that of the controls at 3 h (Table 1). The mitotic index remained at this high level until 15 h after treatment and then declined gradually towards normal values, which were reached by 24 h (Table 1). No distinct morphological abnormalities could be detected in the mit ...
... treatment and was almost twice that of the controls at 3 h (Table 1). The mitotic index remained at this high level until 15 h after treatment and then declined gradually towards normal values, which were reached by 24 h (Table 1). No distinct morphological abnormalities could be detected in the mit ...
traffic jams affect plant development and signal transduction
... Although the basic machinery for vesicular transport is conserved among all eukaryotic cells, the plant endomembrane system also has unique components. In mammals and yeast, each cell has only one type of vacuole, whereas in plants, different types of vacuole — lytic and protein storage — frequently ...
... Although the basic machinery for vesicular transport is conserved among all eukaryotic cells, the plant endomembrane system also has unique components. In mammals and yeast, each cell has only one type of vacuole, whereas in plants, different types of vacuole — lytic and protein storage — frequently ...
EphA2 (D4A2) XP® Rabbit mAb
... EphB receptors bind to ephrin B proteins that have a transmembrane and cytoplasmic domain (1,2). Eph receptors and ligands may be involved in many diseases including cancer (3). Both ephrin A and ephrin B ligands have dual functions. As RTK ligands, the ephrins stimulate the kinase activity of the E ...
... EphB receptors bind to ephrin B proteins that have a transmembrane and cytoplasmic domain (1,2). Eph receptors and ligands may be involved in many diseases including cancer (3). Both ephrin A and ephrin B ligands have dual functions. As RTK ligands, the ephrins stimulate the kinase activity of the E ...
Introduction - Cedar Crest College
... In E. coli, EnvZ is a transmembrane protein that acts as the receptor for changes in solute concentration. It extends into the space between the plasma membrane and the porous outer membrane, which forms a complex with the cell wall. ...
... In E. coli, EnvZ is a transmembrane protein that acts as the receptor for changes in solute concentration. It extends into the space between the plasma membrane and the porous outer membrane, which forms a complex with the cell wall. ...
DNA, Genes, and Chromosomes
... Two exact copies of a chromosome that are connected together. The point where they are connected near the middle is called the centromere. Chromatids are made when new cells are going to be made. ...
... Two exact copies of a chromosome that are connected together. The point where they are connected near the middle is called the centromere. Chromatids are made when new cells are going to be made. ...
Embryonic Stem Cells Maintain an Undifferentiated State on
... proposed for maintaining the undifferentiated state and pluripotent ability of ES cells during in vitro cultures. An example of this includes exogenous stimulation via signaling molecules by introducing them into medium or onto the culture substrate. Some studies have reported that the exogenous sol ...
... proposed for maintaining the undifferentiated state and pluripotent ability of ES cells during in vitro cultures. An example of this includes exogenous stimulation via signaling molecules by introducing them into medium or onto the culture substrate. Some studies have reported that the exogenous sol ...
Two vacuole-mediated defense strategies in plants
... linked to the hypersensitive response (HR), which is accompanied by rapid and localized programmed cell death (PCD) known as hypersensitive cell death. The HR is controlled by multiple signal transduction pathways that are initiated upon recognition of a pathogen avirulence (Avr) factor by a plant r ...
... linked to the hypersensitive response (HR), which is accompanied by rapid and localized programmed cell death (PCD) known as hypersensitive cell death. The HR is controlled by multiple signal transduction pathways that are initiated upon recognition of a pathogen avirulence (Avr) factor by a plant r ...
Cytokinesis
Cytokinesis (cyto- + kinesis) is the process during cell division in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells. It usually initiates during the early stages of mitosis, and sometimes meiosis, splitting a mitotic cell in two, to ensure that chromosome number is maintained from one generation to the next. After cytokinesis two (daughter) cells will be formed that are exact copies of the (parent) original cell. After cytokinesis, each daughter cell is in the interphase portion of the cell cycle. In animal cells, one notable exception to the normal process of cytokinesis is oogenesis (the creation of an ovum in the ovarian follicle of the ovary), where the ovum takes almost all the cytoplasm and organelles, leaving very little for the resulting polar bodies, which then die. Another form of mitosis without cytokinesis occurs in the liver, yielding multinucleate cells. In plant cells, a dividing structure known as the cell plate forms within the centre of the cytoplasm and a new cell wall forms between the two daughter cells.Cytokinesis is distinguished from the prokaryotic process of binary fission.