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Application of the pseudo-plaque assay for detection and titration of
Application of the pseudo-plaque assay for detection and titration of

... was isolated in 2006 from the blood of a patient from the Kelkit Valley region of Turkey (Tonbak et al., 2006). Crimean-Congo hemorrhagic fever virus Turkey-Kelkit06 was passaged 3 times by intracerebral inoculations of 2–3 days old suckling mice. The mice were euthanized 5 days post-infection (PI), ...
Ebolavirus and Marburgvirus Infections
Ebolavirus and Marburgvirus Infections

... for some time in blood and tissues at room temperature, and can be transmitted on fomites, particularly those contaminated by blood. Survival is prolonged when viruses are kept at 4°C. In incidental hosts, filoviruses are thought to enter the body mainly through mucous membranes and broken skin. Art ...
Hepatitis is the inflammation of the liver. Causes include viruses
Hepatitis is the inflammation of the liver. Causes include viruses

... Hepatitis is acute when it lasts less than six months and chronic when it persists longer. The initial symptoms of hepatitis are nonspecific flu­like symptoms, common to almost all acute viral infections and may include malaise, muscle and joint aches, fever, nausea or vomiting, diarrhea, and headac ...
HIV Superinfection - Division of Infectious Diseases
HIV Superinfection - Division of Infectious Diseases

... RNA genome. If a single cell is infected with 2 different HIV strains, an RNA genome from each strain can be packaged into the same virion. Recombination can then occur when this virion infects the next cell and the viral RT enzyme switches from one viral template to the other, creating a mosaic of ...
CYPRINID HERPESVIRUS 3: AN INTERESTING VIRUS FOR APPLIED AND FUNDAMENTAL RESEARCH
CYPRINID HERPESVIRUS 3: AN INTERESTING VIRUS FOR APPLIED AND FUNDAMENTAL RESEARCH

... Manipulation of large herpesvirus genomes has been facilitated by the use of bacterial artificial chromosome (BAC) vectors (Wagner et al. 2002).These vectors allow the stable maintenance and efficient mutagenesis of the viral genome in Escherichia coli (E. coli) followed by the reconstitution of pro ...
Origin of measles virus: divergence from rinderpest virus between
Origin of measles virus: divergence from rinderpest virus between

... civilization in the Middle East. The speculation accords with mathematical analyses as mentioned above [6,9,10]. Molecular clock analysis can estimate the age of ancestors in evolutionary history by phylogenetic patterns [15,16]. The basic approach to estimating molecular dates is to measure the gen ...
Origin of measles virus: divergence from
Origin of measles virus: divergence from

... civilization in the Middle East. The speculation accords with mathematical analyses as mentioned above [6,9,10]. Molecular clock analysis can estimate the age of ancestors in evolutionary history by phylogenetic patterns [15,16]. The basic approach to estimating molecular dates is to measure the gen ...
Book Review: Tetyana Obukhanych, PhD immunologist.
Book Review: Tetyana Obukhanych, PhD immunologist.

... Research in animals had demonstrated that injection of inactivated virus (and most vaccines are made of attenuated or inactivated viruses) was capable of achieving only short duration of protection, during which the serum taken from such animals had virusneutralizing properties. In contrast, inocul ...
PUBVET, Publicações em Medicina Veterinária e Zootecnia
PUBVET, Publicações em Medicina Veterinária e Zootecnia

... endogenous retroviruses (ERVs), contrasted with exogenous ones, now make up 5-8% of the human genome. As insertions have no known function. However, many endogenous retroviruses play important roles in host biology, such as control of gene transcription, cell fusion during placental development in t ...
Feline Upper Respiratory Tract Pathogens
Feline Upper Respiratory Tract Pathogens

... for diagnosis, anatomic site sampled (conjunctival veralso be present in cats with acute infections. In young sus oropharyngeal), number of cats sampled, seasonal cats, damage to the upper respiratory tract epithelium variation of disease, and clinical criteria used to define a and osteolysis of the ...
www.ephysician.ir - Electronic Physician Journal
www.ephysician.ir - Electronic Physician Journal

... Vadodara because people equate H1N1 flu with death due to very high case fatality rate. This is a viral disease and till date no specific treatment is available. Although drug Tamiflu is available but effectiveness is demonstrated in early diagnosed cases which is not always the case in low and midd ...
A survey on presence of new strains of infectious bronchitis virus in
A survey on presence of new strains of infectious bronchitis virus in

... hypervariable regions of the S1 subunit of the envelope spike (S) glycoprotein gene. The S1 protein is responsible for infection of the host cell (Cavanagh & Davis, 1986; Koch et al., 1990) inducing virus neutralizing antibody (Cavanagh et al., 1988) and immunity (Cavanagh et al., 1997). New variant ...
Hepatitis C - Canadian Public Health Association
Hepatitis C - Canadian Public Health Association

... The World Health Organization estimates that up to 3% of the world’s population is infected with hepatitis C virus (HCV) and that there are more than 170 million chronic carriers.1 Many infected people may have no symptoms and are unaware of their condition, and unknowingly act as sources of infecti ...
Susceptibility of farmed juvenile giant grouper
Susceptibility of farmed juvenile giant grouper

... Mahardika et al., 2004; Qin et al., 2003). Our infection experiments results showed that naive giant grouper was susceptible to GIV-R infection with high mortality (80%). The newly isolated ranavirus GIV-R could cause severe systemic disease to juvenile giant grouper, characterized by degeneration a ...
COPD - UniNursety
COPD - UniNursety

... Mycobacterium tuberculosis, measles virus, and varicella [chickenpox] virus) can remain infectious while dispersed over long distances by air currents, causing infection in susceptible individuals who have not had face-to-face contact (or been in the same room) with the infectious individual. Specia ...
Human Herpes Virus-6 and Human Herpes Virus
Human Herpes Virus-6 and Human Herpes Virus

... The comparisons between groups were evaluated using chi-square test, Fisher’s exact test and independent t test. Significant differences (two-tailed p) less than 0.05 were regarded as significant. ...
THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF
THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF

... risk for symptoms not involving the liver. This is because, while the DAAs cure HCV, they do not reverse the effects of the virus that have already been caused, in the liver or elsewhere. Thus, delay in the provision of DAAs to infected persons until their liver deteriorates causes some irreversible ...
Giant toads Bufo marinus in Australia and
Giant toads Bufo marinus in Australia and

... Toads are toxic to predators at all stages of their life cycle; they may compete for food and also act as predators on native fauna. Until recently the transmission of infectious agents from toads was not considered a major threat to Australia's vertebrates. The significance of the toad's expanding ...
PHS 398 (Rev. 11/07), Biographical Sketch Format Page
PHS 398 (Rev. 11/07), Biographical Sketch Format Page

... BMRF1 transcriptional function, but not BMRF1 phosphorylation by the BGLF4-encoded viral kinase, is important for Epstein-Barr virus replication. 4. Seaman, W. T., Gershburg, E., Delecluse, H.-J., Pagano, J. S. and S. C. Kenney. Effects of the EBV-encoded viral kinase, EBV-PK, on BZLF1 function and ...
TWINRIX® ADULT and TWINRIX® JUNIOR
TWINRIX® ADULT and TWINRIX® JUNIOR

... There is no specific treatment for hepatitis A or hepatitis B. Vaccination is the best way to protect against infection. TWINRIX will not protect against hepatitis caused by other agents or viruses (such as hepatitis C or hepatitis E). If a person is already infected with hepatitis A or hepatitis B ...
as Adobe PDF - Edinburgh Research Explorer
as Adobe PDF - Edinburgh Research Explorer

... with HAV, 11 with HBV and 17 with HCV. However, the majority of patients (n = 48, 59%), were shown to be infected with HEV. The number of cases of HEV infection has increased in recent years, with 13 diagnosed in 2012, 20 in 2013 and 15 in the first 4 months of 2013. Despite the introduction of routi ...
Emergence of Acquired HIV-1 Drug Resistance Almost Stopped in
Emergence of Acquired HIV-1 Drug Resistance Almost Stopped in

... (GRTs) performed by all authorized laboratories in Switzerland. Sequences are stored in a central database (SmartGene; Integrated Database Network System version 3.6.13). All laboratories perform population-based sequencing [5, 20]. The SHCS is highly representative and includes 72% of the patients ...
A Review of Melanie`s Marvelous Measles
A Review of Melanie`s Marvelous Measles

... Indeed, according to the representatives of the medical establishment and public health, measles can be a deadly disease. This statement is entirely correct and factual. In addition to making it more prevalent in (young) infants via mass vaccination of the generation of their mothers, there are in f ...
Biliary atresia
Biliary atresia

... (PCR), potential role ROTAVIRUS . rotavirus inoculation was found to induce EHBA in newborn mice ...
Vomiting as a Symptom and Transmission Risk in Norovirus
Vomiting as a Symptom and Transmission Risk in Norovirus

... Snow Mountain viruses were similar, but the cumulative shedding during Hawaii virus infection was 2–3 logs lower than the other viruses (2.3x105). However, it should be noted that only one subject infected with Hawaii virus had sample volume data available. The relationship between virus titers in e ...
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Antiviral drug

Antiviral drugs are a class of medication used specifically for treating viral infections. Like antibiotics for bacteria, specific antivirals are used for specific viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit their development.Antiviral drugs are one class of antimicrobials, a larger group which also includes antibiotic (also termed antibacterial), antifungal and antiparasitic drugs, or antiviral drugs based on monoclonal antibodies. Most antivirals are considered relatively harmless to the host, and therefore can be used to treat infections. They should be distinguished from viricides, which are not medication but deactivate or destroy virus particles, either inside or outside the body. Antivirals also can be found in essential oils of some herbs, such as eucalyptus oil and its constituents.
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