• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Buprenorphine Treatment of Refractory
Buprenorphine Treatment of Refractory

... century, the eminent authority Emil Kraepelin recommended tincture of opium for the acute treatment of agitated depression. [2] This use of opium and its derivatives continued to be recommended in psychiatric textbooks until as recently as 1956. [3] However, before the development of modern methods ...
DESIGN DEVELOPMENT AND EVALUATION OF MATRIX TABLETS OF AMBROXOL Original Article
DESIGN DEVELOPMENT AND EVALUATION OF MATRIX TABLETS OF AMBROXOL Original Article

... From the data obtained it was observed that all the formulations showed higher regression coefficient values for first order release of the drug (r2 value; 0.9721 to 0.9928) as compared to zero order release kinetics (r2 value; 0.8793 to 0.9267) indicating that the release of drug followed first ord ...
to - CME Medical
to - CME Medical

... Myfuser flow restrictor capillary is obtained from high quality GLASS of German production. Our technical personnel is engaged in constant control of each single flow restrictor before being assembled in Myfuser. The choice of a glass capillary is justified by the mechanical properties of this mater ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Perception of pain is a major concern for most of the surgical patients. Postoperative pain1 is an acute pain which initiate a systemic stress response 2 that encompasses a wide range of neuroendocrine, immunological, and haematological responses. The overall metabolic effect is one of catabolism of ...
A Missense Cystic Fibrosis Transmembrane
A Missense Cystic Fibrosis Transmembrane

... male genital system. It therefore results in progressive lung disease, pancreatic and intestinal dysfunction, elevated sweat electrolytes, and male infertility.1 CF is characterized by a wide variability of clinical expression. The cloning of the CFTR gene and the identification of mutations in the ...
calibration - Beckman Coulter
calibration - Beckman Coulter

... medicine. Heroin, the principal opiate of abuse, is a semi-synthetic derivative of morphine. Opiates are absorbed rapidly after administration. Approximately 90 percent of morphine and codeine is excreted in urine as conjugated metabolites. Heroin is metabolized to morphine and follows a similar uri ...
Administering Medication
Administering Medication

... Preparing Insulin Therapy When preparing U-100 insulin, use a U100-unit-scaled syringe.  Always have a second nurse double-check insulin for right drug, dose, etc.  Gently roll (not shake) all cloudy insulin for resuspension of insulin. ...
PENTAZOCINE VERSUS PENTAZOCINE WITH RECTAL DICLOFENAC FOR POSTOPERATIVE PAIN
PENTAZOCINE VERSUS PENTAZOCINE WITH RECTAL DICLOFENAC FOR POSTOPERATIVE PAIN

... for postoperative analgesia with limited effect3. A multimodal approach has been proposed to be more effective2. Non-steroidal anti-inflammatory drugs (NSAIDs) have beneficial effect on postoperative analgesia and are devoid of adverse effects associated with opioids such as sedation, respiratory de ...
The true ramifications of genetic criminality research
The true ramifications of genetic criminality research

... their reduced mental ability, but XYY males proved to be no more violent than the population at large – their higher incarceration rate was the result of mostly petty property crimes.40 Like MAOA deficiency, the story of XYY shows that the additional knowledge we have gained since Lombroso’s time ha ...
GENERIC DRUGS: OPTIMIZING THE FUTURE
GENERIC DRUGS: OPTIMIZING THE FUTURE

... In 2011, products with sales of more than $30 billion face generic competition as many major brand name drugs lose market exclusivity. However, the industry will face the full impact of patients shifting to lowercost generics, as well as other brands in their therapy classes, in 2012. This is due to ...
protocol
protocol

... 4. No data will be moved/shared outside of Baystate Medical Center. If presenting the analyzed data for research meetings or publication, then only the de-identified data will be presented. Risks and benefits: Multiple studies have shown clonidine used in the above mentioned doses to have relatively ...
Paternal Exposures—Reproductive Risks
Paternal Exposures—Reproductive Risks

... mechanisms may be useful once repeat studies are done and information is available on specific agents or combinations that are associated with male-mediated effects on the progeny. Recreational exposure Paternal exposures to most ‘‘recreational drugs’’ such as caffeine, cocaine, and methadone have n ...
Chapter-1 Introduction 1.1 INTRODUCTION
Chapter-1 Introduction 1.1 INTRODUCTION

... F Wehling 1996). The major advantages with effervescent formulation approach that it is a well established, easy to implement and mask the bitter taste of drug. The effervescent system is generally composed of a dry acid and dry base which when react facilitate a mild effervescent reaction when the ...
Psychotoxic or Psychedelic - Scholarly Commons
Psychotoxic or Psychedelic - Scholarly Commons

... these reasons, the psychotomimetics have been valuable in the study of the biochemical function of the nervous system. The foregoing brief discussion of the action of, psychotomimetic drugs has been presented so that a basis of comparison can be made with the effects from the inhalation of solvents ...
Rituxan for RA CC
Rituxan for RA CC

... 100 mg (10 mL) or 500 mg (50 mL) single-use vials. The dose is diluted before IV infusion. The rate of the infusion is gradually increased as tolerated up to a maximum rate of 400 mg/hour. If an infusion reaction occurs, the infusion is interrupted or the rate is decreased. If necessary medical mana ...
CNS Analgesic Agents
CNS Analgesic Agents

... CNS – Analgesic Agents Classification of Pain  Classification of pain by onset and duration: ...
Glycopeptides, Oxazolidinones, Streptogramins and
Glycopeptides, Oxazolidinones, Streptogramins and

...  Concentration-dependent killing  Post antibiotic effect  Once daily dosing  Excreted mainly through kidneys ...
- Wiley Online Library
- Wiley Online Library

... the chromosomal background of ␤-thalassemia mutations in several human populations. The eastern region of India is not well characterized in this regard. The Bengali population from the state of West Bengal has been the subject of our study. It is an admixture of native people with later migrants wh ...
The PTPN22 R620W mutation is independent of HLA
The PTPN22 R620W mutation is independent of HLA

... binding element in the IKBL promoter by the IKBL-62T SNP has been described in binding studies [34], which of interest is a sequence shared in many B and T cell lineage specific genes. Decreased IKBL promoter activity has also been functionally associated with the IKBL-62A allele, culminating in an ...
a review on sarpagandha
a review on sarpagandha

... herb because of apparent benefits over the The authors suggest, it is prudent to use extract. The whole herb has many compothe whole herb for therapeutic applicanents which can tions, until and unless any chemical de(1) Help in biotransformation into pharmarivative is proved to be better than the co ...
Chapter 10 and 13
Chapter 10 and 13

... How to Solve Genetics Problems Sample Problem: Mom and dad are heterozygous for tongue rolling where tongue rolling is dominant to non-rolling. What is the chance that the couple will produce a girl that is a non-roller? Use the following steps as a general guide to solve this and other problems: 1. ...
Here - Papworth Hospital
Here - Papworth Hospital

... interested in how HPO could help deliver the bio-informatics frameworks for further analysis. Here help was requested for the conversion of ICD codes into HPO (various tools are available!) and there was also interest in the ‘Phenogrid widget’ to identify possible causative genes based on Phenotype ...
Methadone
Methadone

...  CONVERT BACK TO BUPRENORPHINE AT DISCHARGE ...
chapter fourteen
chapter fourteen

Anesthesia and Neuromuscular Blockade - Power
Anesthesia and Neuromuscular Blockade - Power

< 1 ... 360 361 362 363 364 365 366 367 368 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report