Hypertension
... Renal artery stenosis Cushing’s syndrome Coarctation of the aorta Drug-induced: NSAIDs; Prophylactic; Mineralocorticoids; Epogen ...
... Renal artery stenosis Cushing’s syndrome Coarctation of the aorta Drug-induced: NSAIDs; Prophylactic; Mineralocorticoids; Epogen ...
Drug Receptors
... Drugs act on the cell membrane by physical and/or chemical interactionsusually through specific drug receptor sites known to be located on the membrane. Some receptor sites have been identified with specific parts of proteins and nucleic acids. In most cases, the chemical nature of the receptor site ...
... Drugs act on the cell membrane by physical and/or chemical interactionsusually through specific drug receptor sites known to be located on the membrane. Some receptor sites have been identified with specific parts of proteins and nucleic acids. In most cases, the chemical nature of the receptor site ...
Volume 30 • Number 6 • 2013 - Controlled Release Society
... might reasonably say that my crystal ball is as cloudy and fuzzy as any other CRS member’s, and you would be right—so here is my philosophy rather than my vision. To some degree at least, we can and do rationally create the future, but the complexity of possible interactions between scientific disci ...
... might reasonably say that my crystal ball is as cloudy and fuzzy as any other CRS member’s, and you would be right—so here is my philosophy rather than my vision. To some degree at least, we can and do rationally create the future, but the complexity of possible interactions between scientific disci ...
Guidelines for surveillance of drug resistance in tuberculosis
... This fifth edition of the Guidelines for surveillance of drug resistance in tuberculosis is an updated version of earlier editions published in 1994 (1), 1997 (2), 2003 (3) and 2009 (4). The document takes into account recent advancements in laboratory diagnostics and subsequent WHO guidance, includ ...
... This fifth edition of the Guidelines for surveillance of drug resistance in tuberculosis is an updated version of earlier editions published in 1994 (1), 1997 (2), 2003 (3) and 2009 (4). The document takes into account recent advancements in laboratory diagnostics and subsequent WHO guidance, includ ...
SUMMARY OF PRODUCT CHARACTERISTICS
... estimated that a breastfed infant may receive 1,4 % of the mother’s weight adjusted dose, and pharmacological effects on the suckling infant cannot be excluded. Zopiclone should therefore not be used during breast-feeding. Fertility There are no adequate data from potential effects on human fertilit ...
... estimated that a breastfed infant may receive 1,4 % of the mother’s weight adjusted dose, and pharmacological effects on the suckling infant cannot be excluded. Zopiclone should therefore not be used during breast-feeding. Fertility There are no adequate data from potential effects on human fertilit ...
IOSR Journal of Applied Physics (IOSR-JAP) e-ISSN: 2278-4861.
... Abstract: In radiotherapy treatment there are many potential error sources, which can increase the uncertainty in the dose delivery to a patient to unacceptable values. Potential error sources can be divided into four categories(1,2); (1) errors in the data transfer from treatment planning system (T ...
... Abstract: In radiotherapy treatment there are many potential error sources, which can increase the uncertainty in the dose delivery to a patient to unacceptable values. Potential error sources can be divided into four categories(1,2); (1) errors in the data transfer from treatment planning system (T ...
Stilnox - Sanofi
... demonstrated that with food, mean AUC and C max were decreased by 15% and 25%, respectively, while mean T max was prolonged by 60% (from 1.4 to 2.2 hr). The half-life remained unchanged. These results suggest that, for faster sleep onset, STILNOX should not be administered with or immediately after ...
... demonstrated that with food, mean AUC and C max were decreased by 15% and 25%, respectively, while mean T max was prolonged by 60% (from 1.4 to 2.2 hr). The half-life remained unchanged. These results suggest that, for faster sleep onset, STILNOX should not be administered with or immediately after ...
voltaren ophtha
... Although systemic absorption of diclofenac sodium has been found to be minimal following ocular application, as a general precaution to reduce systemic absorption, pressure should be applied to the tear-duct immediately after application. In clinical studies, effectiveness was demonstrated in patien ...
... Although systemic absorption of diclofenac sodium has been found to be minimal following ocular application, as a general precaution to reduce systemic absorption, pressure should be applied to the tear-duct immediately after application. In clinical studies, effectiveness was demonstrated in patien ...
to dowload a PDF of the 2015 Treatment Guide
... “unacceptable toxicity,” the drug moves to Phase II to test its effectiveness in people who have HIV. This is when something called a controlled trial begins. Patients receiving the drug are compared with similar patients receiving only a placebo, or an entirely different drug. The focus is on short ...
... “unacceptable toxicity,” the drug moves to Phase II to test its effectiveness in people who have HIV. This is when something called a controlled trial begins. Patients receiving the drug are compared with similar patients receiving only a placebo, or an entirely different drug. The focus is on short ...
Imunovir®500mg Tablets
... patients diagnosed with SSPE was evaluated in a Phase III trial (1997-2002). There were no statistically significant differences between treatment groups on any measure of efficacy. Although there was no significant difference between the treatment groups in rates of clinically defined satisfactory ...
... patients diagnosed with SSPE was evaluated in a Phase III trial (1997-2002). There were no statistically significant differences between treatment groups on any measure of efficacy. Although there was no significant difference between the treatment groups in rates of clinically defined satisfactory ...
enzyme induction and inhibition
... drugs under the same influence. Another disadvantage of antipyrine as a model drug is its ability to act as a mild enzyme inducer; it therefore may stimulate its own metabolism and the metabolism of other drugs such as warfarin and diazepam (Bax et al., 1981; Ohnhaus and Park, 1979; Breckenridge et ...
... drugs under the same influence. Another disadvantage of antipyrine as a model drug is its ability to act as a mild enzyme inducer; it therefore may stimulate its own metabolism and the metabolism of other drugs such as warfarin and diazepam (Bax et al., 1981; Ohnhaus and Park, 1979; Breckenridge et ...
A Pharmacokinetic-Pharmacodynamic Model to Optimize
... mechanism of action is blocking of the CCR5 receptor, which is used by HIV to enter CD4+ cells. Pharmacokinetic/ pharmacodynamic models are ideally developed during the learning phase and then utilized in the design of the confirming phase of drug development. It is important that the models allow b ...
... mechanism of action is blocking of the CCR5 receptor, which is used by HIV to enter CD4+ cells. Pharmacokinetic/ pharmacodynamic models are ideally developed during the learning phase and then utilized in the design of the confirming phase of drug development. It is important that the models allow b ...
Fast Dissolving Tablets- A Novel Approach
... with ever increasing demand. Fast dissolving tablet (FDT) is one such type of an innovative and unique drug delivery system which is swiftly gaining much attention in the research field of rapid dissolving technology. Oral route is the most expedient and safest route of drug delivery because of wide ...
... with ever increasing demand. Fast dissolving tablet (FDT) is one such type of an innovative and unique drug delivery system which is swiftly gaining much attention in the research field of rapid dissolving technology. Oral route is the most expedient and safest route of drug delivery because of wide ...
Genomic selection: the future of marker assisted selection and animal breeding
... same accuracy of selection can be maintained. The latter is not possible in phenotypic selection schemes, because the animals have not been phenotyped, and it is also not possible in schemes where only a part of the total genetic variance is explained by genetic markers. In the following, genomic se ...
... same accuracy of selection can be maintained. The latter is not possible in phenotypic selection schemes, because the animals have not been phenotyped, and it is also not possible in schemes where only a part of the total genetic variance is explained by genetic markers. In the following, genomic se ...
PowerPoint Presentation - Lecture 11
... - Need to teach clients how to use properly: If using Atrovent w/ a beta-agonist, use beta-agonist 5 min. before Atrovent; If using Atrovent w/ an inhaled steroid or cromolyn, use Atrovent 5 min. before the steroid or cromolyn - bronchioles dilate & drugs more effective ...
... - Need to teach clients how to use properly: If using Atrovent w/ a beta-agonist, use beta-agonist 5 min. before Atrovent; If using Atrovent w/ an inhaled steroid or cromolyn, use Atrovent 5 min. before the steroid or cromolyn - bronchioles dilate & drugs more effective ...
Diamond–Blackfan anemia
... relatively rarely transfused. However, it is a therapy that carries life-threatening risk for a non-malignant disease, whose prognosis might be modified in the coming decade by advances made in our understanding of its pathophysiology. This decision must be made case-by-case. Certain treatments of D ...
... relatively rarely transfused. However, it is a therapy that carries life-threatening risk for a non-malignant disease, whose prognosis might be modified in the coming decade by advances made in our understanding of its pathophysiology. This decision must be made case-by-case. Certain treatments of D ...
PCSK9 Inhibitors Praluent
... respective gene that reduces the liver's ability to remove LDL cholesterol before it is released into the bloodstream. Restricting this protein’s ability to hinder the liver by using PCSK9-inhibiting drugs has shown to lower LDL-C as much as 52%. Studies to date have shown that adverse events are ma ...
... respective gene that reduces the liver's ability to remove LDL cholesterol before it is released into the bloodstream. Restricting this protein’s ability to hinder the liver by using PCSK9-inhibiting drugs has shown to lower LDL-C as much as 52%. Studies to date have shown that adverse events are ma ...
EKOS ® Acoustic Pulse Thrombolysis ™ Treatment
... vasculature. The EkoSonic™ Endovascular System is CE Marked for the treatment of pulmonary embolism with a ≥50% clot burden in one or both main pulmonary arteries or lobar pulmonary arteries, and evidence of right heart dysfunction based on right heart pressures (mean pulmonary artery pressure ≥25 m ...
... vasculature. The EkoSonic™ Endovascular System is CE Marked for the treatment of pulmonary embolism with a ≥50% clot burden in one or both main pulmonary arteries or lobar pulmonary arteries, and evidence of right heart dysfunction based on right heart pressures (mean pulmonary artery pressure ≥25 m ...
Animal Drug User Fee Programs Updated August 4, 2008 Sarah A. Lister
... in the timeliness of reviews, and the elimination of a backlog of pre-approval inspections of foreign manufacturing facilities. FDA presented draft reauthorizing legislation to Congress in April 2008. H.R. 6432, the Animal Drug User Fee Amendments of 2008, a bill to reauthorize the program, was intr ...
... in the timeliness of reviews, and the elimination of a backlog of pre-approval inspections of foreign manufacturing facilities. FDA presented draft reauthorizing legislation to Congress in April 2008. H.R. 6432, the Animal Drug User Fee Amendments of 2008, a bill to reauthorize the program, was intr ...
Genetic Basis of Variation in Bacteria Genetic Basis of Variation in
... There are two types of transduction: – generalized transduction: A DNA fragment is transferred from one bacterium to another by a lytic bacteriophage that is now carrying donor bacterial DNA due to an error in maturation during the lytic life cycle. – specialized transduction: A DNA fragment is tran ...
... There are two types of transduction: – generalized transduction: A DNA fragment is transferred from one bacterium to another by a lytic bacteriophage that is now carrying donor bacterial DNA due to an error in maturation during the lytic life cycle. – specialized transduction: A DNA fragment is tran ...
Drug Interactions Among HIV Patients Receiving
... The dideoxynucleoside analogs known to cause PN are didanosine, stavudine, and zalcitabine (discontinued by the manufacturer in the United States in 2006).5 These have the highest incidence of iatrogenic neuropathy and were the main cause of drug-induced DSPN prior to HAART. DSPN occurs more frequen ...
... The dideoxynucleoside analogs known to cause PN are didanosine, stavudine, and zalcitabine (discontinued by the manufacturer in the United States in 2006).5 These have the highest incidence of iatrogenic neuropathy and were the main cause of drug-induced DSPN prior to HAART. DSPN occurs more frequen ...
Antiretroviral Therapy 2014
... The treatment of Human Immune Deficiency Virus (HIV) has been revolutionized by new potent combination of highly active antiretroviral drugs (HAART) since 1996. ART (antiretroviral therapy) has dramatically reduced HIV-associated morbidity and mortality and has transformed HIV disease into a chroni ...
... The treatment of Human Immune Deficiency Virus (HIV) has been revolutionized by new potent combination of highly active antiretroviral drugs (HAART) since 1996. ART (antiretroviral therapy) has dramatically reduced HIV-associated morbidity and mortality and has transformed HIV disease into a chroni ...