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Cobalt(II) chloride hexahydrate
Cobalt(II) chloride hexahydrate

... ! Skin contact is not thought to produce harmful health effects (as classified using animal models). Systemic harm, however, has been identified following exposure of animals by at least one other route and the material may still produce health damage following entry through wounds, lesions or abras ...
determination on whether a substance is a hazardous substance
determination on whether a substance is a hazardous substance

... form (attached as Appendix 1 to this document). It is noted that often limited or no information was available on these types of substances for a number of endpoints, especially data on fluoropolymers as a group. Where information was available on specific fluoropolymers, this has been provided. How ...
PERSPECTIVE Rationale and Procedures for Using the Tissue
PERSPECTIVE Rationale and Procedures for Using the Tissue

... of a detailed examination of the data for each compound and emphasize careful selection of compounds based on mechanism of action when considering mixtures or broad classifications. More importantly, several factors (see list in next section) must be considered before an accurate assessment can be m ...
Additivity and Interactions in Ecotoxicity of Pollutant Mixtures: Some
Additivity and Interactions in Ecotoxicity of Pollutant Mixtures: Some

... system”); synergism (“when the effect of the mixture is greater than that estimated for additivity on the basis of the toxicities of the components”); potentiation (“when a component that does not have a toxic effect on an organ system increases the effect of a second chemical on that organ system”) ...
Millennium Ecosystem Assessment
Millennium Ecosystem Assessment

... All comments will be addressed by authors Independent Review Board (85 experts; chaired by José Sarukhán and Anne Whyte) will examine responses and determine whether the comments have been adequately addressed by authors ...
DOC - unece
DOC - unece

... toxicity, developmental toxicity, reproductive ability and capacity, class and category” which are used in paragraphs 3.7.2.1 and 3.7.2.2.1 of the GHS. It is one of the programme elements for the biennium 2003-2004. ...
Calcium carbide - Santa Cruz Biotechnology
Calcium carbide - Santa Cruz Biotechnology

... characterized by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result. SKIN ! The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires tha ...
Chapter 164 - Plants, Mushrooms, and Herbal Medications
Chapter 164 - Plants, Mushrooms, and Herbal Medications

... Nerium oleander (Fig. 164-6), or oleander, is one of many plants that contain toxic cardiac glycosides37,38 structurally similar to digoxin. Ingestion of several leaves is unlikely to cause serious symptoms.39,40 Large exposures from suicide attempts or misidentification of plants used for teas or h ...
Sodium Ascorbyl Phosphate
Sodium Ascorbyl Phosphate

... At the customer site, one to 2 store personnel will receive the drums containing the notified chemical. Drums will be carried on pallets or individually on forklifts to quarantine and sampling areas, and then to the manufacturing site. The total delivery time could be up to 10 minutes with an expect ...
PIC Chemicals - Rotterdam Convention
PIC Chemicals - Rotterdam Convention

... This booklet provides basic information on the chemicals listed in Annex III of the Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade. The Rotterdam Convention is a global treaty that provides an early warning to count ...
9. evaluation of toxicological data
9. evaluation of toxicological data

... with antistatic plastic. It will then be transported by road to industrial establishments for formulation into masterbatch. There is not expected to be any exposure to the notified chemical during storage and distribution, except in the event of a spill. Occupational exposure is likely to occur only ...
Alarm substance from adult zebrafish alters early embryonic
Alarm substance from adult zebrafish alters early embryonic

... in response to predation threat are common place (e.g. Tollrian 1995) but may have associated costs (Peckarsky et al. 2002). Alternatively, the early occurrence of developmental events could relate to later physiological or behavioural traits, as has been demonstrated in tadpoles, which learnt to re ...
Vitamins: a brief guide
Vitamins: a brief guide

... In 1921, the British biochemist Sir Jack Cecil Drummond suggested combining the use of letters of the alphabet with the term ‘vitamin’ to denote a range of related organic micronutrients. These micronutrients consequently became known as vitamins A, B, C and so on. ...
Environmental Defense – DuPont Nano Partnership  February 26, 2007
Environmental Defense – DuPont Nano Partnership February 26, 2007

... considering, determine how to manage those risks, and communicate their decisions to stakeholders such as workers, customers, suppliers, and the public. The Framework can also be useful to other stakeholders, such as government officials, financial institutions, and NGOs. Given the team members’ are ...
There`s xylitol in that too?
There`s xylitol in that too?

... The toxicity of xylitol is dose dependent. The dose necessary to cause hypoglycemia in dogs is approximately 0.1 grams/kg, while the amount needed to cause hepatic necrosis is approximately 0.5 grams/kg. Rarely, hepatic necrosis can be seen without prior hypoglycemia. Most chewing gums and breath mi ...
and poly-fluoroalkyl substances (PFAS)
and poly-fluoroalkyl substances (PFAS)

... broken down in the body. These chemicals are only very slowly eliminated from the body. Studies have shown that Australians have small amounts of PFOS and PFOA in their blood. PFOS and PFOA can also be found in urine and breast milk. People who work in industries that use PFOS and PFOA, or use produ ...
Biodegradation of persistent chlorinated
Biodegradation of persistent chlorinated

... detected in the aquatic and terrestrial species including human decades after their application to soil [2,3]. Such bioaccumulation represents a great threat since DDT metabolites are both toxic and estrogenic and can alter reproductive development in reptiles and mammals [4-8]. Therefore, remediati ...
Québec Pesticide Strategy 2015-2018
Québec Pesticide Strategy 2015-2018

... The use of all neonicotinoids on lawns and flower beds for esthetic purposes will be banned. This proposal will allow Québec to join Ontario’s approach, which since 2009 has banned the use of pesticides (including neonicotinoids) for esthetic purposes on lawns and in individual gardens. Québec will ...
Information about GB Non-native Species Risk Assessments
Information about GB Non-native Species Risk Assessments

... The Convention on Biological Diversity (CBD) emphasises the need for a precautionary approach towards non-native species where there is often a lack of firm scientific evidence. It also strongly promotes the use of good quality risk assessment to help underpin this approach. The GB risk analysis mec ...
Annex XV report PROPOSAL FOR IDENTIFICATION OF A
Annex XV report PROPOSAL FOR IDENTIFICATION OF A

... high concern in accordance with Article 57(f) of Regulation (EC) 1907/2006 (REACH) because it is a substance with skin sensitising properties for which there is scientific evidence of probable serious effects to human health which gives rise to an equivalent level of concern (ELoC) to those substanc ...
NA/320 - NICNAS
NA/320 - NICNAS

... Due to a high Tyndall effect and the formation of micelles (CMC = 0.4 g.L-1), solubility behaviour deviates from that of simple organics. The chemical is dispersible in water (Priazul 2118 is a nonionic surfactant). No hydrolysis data was available for the notified chemical. Hydrolysis of the chemic ...
LD50 - ctaeir.org
LD50 - ctaeir.org

... Instructions: Read the material and make notes of important points, answer questions, and be ready to discuss this topic. ...
Toxicology (Introduction) - Home
Toxicology (Introduction) - Home

... -Chemicals in liquid form are more toxic than those in solid form -Coloring agents as tartazin yellow cause allergy. -Micronization increase toxicity. -Vehicles as alcohols increase CNS depressant action of hypnotics. -Impurities; some herbicide as 2,4,5-trichlorophenoxy acetic acid may contain the ...
STD/1490
STD/1490

... and Assessment) Act 1989 (Cwlth) (the Act) and Regulations. This legislation is an Act of the Commonwealth of Australia. The National Industrial Chemicals Notification and Assessment Scheme (NICNAS) is administered by the Department of Health, and conducts the risk assessment for public health and o ...
9. evaluation of toxicological data
9. evaluation of toxicological data

... import containers of notified chemical. These operators will transfer the chemical from import containers into storage tanks via a spear/hose connected to a pump. From storage containers, the notified chemical will be metered automatically into a closed 1000L mixing tank where the chemical is mixed ...
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Biocide

A biocide is defined in the European legislation as a chemical substance or microorganism intended to destroy, deter, render harmless, or exert a controlling effect on any harmful organism by chemical or biological means. The US Environmental Protection Agency (EPA) uses a slightly differenct definition for biocides as ""a diverse group of poisonous substances including preservatives, insecticides, disinfectants, and pesticides used for the control of organisms that are harmful to human or animal health or that cause damage to natural or manufactured products"". When compared, the two definitions roughly imply the same, although the US EPA definition includes plant protection products and some veterinary medicines.The terms ""biocides"" and ""pesticides"" are regularly interchanged, and often confused with ""plant protection products"". To clarify this, pesticides include both biocides and plant protection products, where the former regards substances for non food and feed purposes and the latter regards substances for food and feed purposes.When discussing biocides a distinction should be made between the biocidal active substance and the biocidal product. The biocidal active substances are mostly chemical compounds, but can also be microorganisms (e.g. bacteria). Biocidal products contain one or more biocidal active substances and may contain other non-active co-formulants that ensure the effectiveness as well as the desired pH, viscosity, colour, odour, etc. of the final product. Biocidal products are available on the market for use by professional and/or non-professional consumers.Although most of the biocidal active substances have a relative high toxicity; there are also examples of active substances with low toxicity, such as CO2, which exhibit their biocidal activity only under certain specific conditions such as in closed systems. In such cases, the biocidal product is the combination of the active substance and the device that ensures the intended biocidal activity, i.e. suffocation of rodents by CO2 in a closed system trap. Another example of biocidal products available to consumers are products impregnated with biocides (also called treated articles), such as clothes and wristbands impregnated with insecticides, socks impregnated with antibacterial substances etc.Biocides are commonly used in medicine, agriculture, forestry, and industry. Biocidal substances and products are also employed as anti-fouling agents or disinfectants under other circumstances: chlorine, for example, is used as a short-life biocide in industrial water treatment but as a disinfectant in swimming pools. Many biocides are synthetic, but there are naturally occurring biocides classified as natural biocides, derived from, e.g., bacteria and plants.A biocide can be: A pesticide: this includes fungicides, herbicides, insecticides, algicides, molluscicides, miticides and rodenticides. An antimicrobial: this includes germicides, antibiotics, antibacterials, antivirals, antifungals, antiprotozoals and antiparasites. See also spermicide.Biocide can also refer to the destruction of life, a form of omnicide that affects every living thing, not just humans; one who wishes that everything in the entire world, or universe, face extinction, is labeled a 'Biocidist', or having 'biocidal' ideologies.
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