COMPARATIVE EVALUATION OF POTATO STARCH AND BANANA POWDER AS
... Objective: The main objective of this research was to introduce and evaluate disintegrant property of natural excipients like potato starch and banana powder in tablet formulation. Pharmaceutical excipients developed from natural sources are economic. Methods: Dehydrated banana powder and potato sta ...
... Objective: The main objective of this research was to introduce and evaluate disintegrant property of natural excipients like potato starch and banana powder in tablet formulation. Pharmaceutical excipients developed from natural sources are economic. Methods: Dehydrated banana powder and potato sta ...
An Analysis of the Generic Pharmaceutical Industries in Brazil and
... patent protection allowed developing countries with pharmaceutical industries to manufacture generic versions of high cost drugs (patented in developed countries) at a lower and more affordable cost. Developing countries without pharmaceutical industries also benefited because they could legally imp ...
... patent protection allowed developing countries with pharmaceutical industries to manufacture generic versions of high cost drugs (patented in developed countries) at a lower and more affordable cost. Developing countries without pharmaceutical industries also benefited because they could legally imp ...
Distribution of drugs
... - Diflunisal: not antipyretic (unlike aspirin), only anti-inflammatory - Suramine: is not useful against trypanosomia in brain (→ → melarsoprol) Yet, donepezil (an anti-Alzheimer drug) is 96% PPB, but easily crosses the BBB and its Vd is 12 L/kg! Explanation: Donepezil is lipophilic and PPB is an eq ...
... - Diflunisal: not antipyretic (unlike aspirin), only anti-inflammatory - Suramine: is not useful against trypanosomia in brain (→ → melarsoprol) Yet, donepezil (an anti-Alzheimer drug) is 96% PPB, but easily crosses the BBB and its Vd is 12 L/kg! Explanation: Donepezil is lipophilic and PPB is an eq ...
bargain kinerase
... he science and art of Pharmacy is ever evolving and with it the pharmacist is embracing newer professional roles. Indeed the patient experience has transformed in the last decade. The Pharmacist is a key player in the healthcare team providing a more direct and relevant contribution than in the past ...
... he science and art of Pharmacy is ever evolving and with it the pharmacist is embracing newer professional roles. Indeed the patient experience has transformed in the last decade. The Pharmacist is a key player in the healthcare team providing a more direct and relevant contribution than in the past ...
Guidelines
... “Given the difficulties associated with collecting bioequivalence data with this product, the program suggests that the applicant employ one of the two following options:….” ...
... “Given the difficulties associated with collecting bioequivalence data with this product, the program suggests that the applicant employ one of the two following options:….” ...
Drug, substance that affects the function of living cells
... exclusive right to make and sell a drug, then the drug is available under one brand name only. After the patent expires, typically after 17 years in the United States, other companies can also manufacture the drug and market it under the generic name, or give it a new brand name. Another way to cate ...
... exclusive right to make and sell a drug, then the drug is available under one brand name only. After the patent expires, typically after 17 years in the United States, other companies can also manufacture the drug and market it under the generic name, or give it a new brand name. Another way to cate ...
Me-too drugs: is there a problem
... for most patients, while others are better for a substantial fraction of patients. The increased choice between drugs can be very valuable, particularly for patients for whom the pioneer drug is ineffective or entails undesirable side effects.2 In addition, for some classes of drugs, such as antibio ...
... for most patients, while others are better for a substantial fraction of patients. The increased choice between drugs can be very valuable, particularly for patients for whom the pioneer drug is ineffective or entails undesirable side effects.2 In addition, for some classes of drugs, such as antibio ...
10 × `20 Progress—Development of New Drugs Active Against Gram
... with leaders of the few remaining pharmaceutical and biotechnology companies identified in our earlier survey [2]; the websites of these companies were also accessed and data on drugs in development were reviewed. We focus on new orally or intravenously administered antibiotics that have progressed t ...
... with leaders of the few remaining pharmaceutical and biotechnology companies identified in our earlier survey [2]; the websites of these companies were also accessed and data on drugs in development were reviewed. We focus on new orally or intravenously administered antibiotics that have progressed t ...
Reflection paper on the use of cocrystals of active - EMA
... the lack of clinical significance demonstrated, e.g., by comparison of the intrinsic solubility, etc. The relevant sections of the dossier such as manufacturing description and formula, specifications, etc., must take into account the actual forms used. The SmPC may use wording under section 2 that ...
... the lack of clinical significance demonstrated, e.g., by comparison of the intrinsic solubility, etc. The relevant sections of the dossier such as manufacturing description and formula, specifications, etc., must take into account the actual forms used. The SmPC may use wording under section 2 that ...
Pharm D (Post Baccalaureate)
... 3. Objectives of project work ― The main objectives of the project work is to― (i) show the evidence of having made accurate description of published work of others and of having recorded the findings in an impartial manner; and (ii) develop the students in data collection, analysis and reporting an ...
... 3. Objectives of project work ― The main objectives of the project work is to― (i) show the evidence of having made accurate description of published work of others and of having recorded the findings in an impartial manner; and (ii) develop the students in data collection, analysis and reporting an ...
Direct-to-Consumer Advertising of Prescription
... Several submitters considered that DTCA is unable to provide full and balanced information. There was strong concern that such advertising misrepresents particular products, is biased and incomplete and could result in confused, misinformed and anxious consumers. Some submitters specifically commen ...
... Several submitters considered that DTCA is unable to provide full and balanced information. There was strong concern that such advertising misrepresents particular products, is biased and incomplete and could result in confused, misinformed and anxious consumers. Some submitters specifically commen ...
DRUGS THAT AFFECT CARDIOVASCULAR FUNCTIONS
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
drugs that affect cardiovascular system
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
Level of Evidence Associated with FDA Safety Communications with
... Purpose: Approximately 800,000 safety reports are submitted to the FDA annually, however, only significant issues generate drug safety communications (DSC). The purpose of this study was to determine the type of clinical evidence used to warrant a change in drug labeling for drugs with DSC between J ...
... Purpose: Approximately 800,000 safety reports are submitted to the FDA annually, however, only significant issues generate drug safety communications (DSC). The purpose of this study was to determine the type of clinical evidence used to warrant a change in drug labeling for drugs with DSC between J ...
Demystifying FDA`s 505(b)(2) Drug Registration Process
... Depending upon the nature and scope of efficacy studies required by FDA for 505(b)(2) drugs, an integrated summary of efficacy may be required. This requirement is more likely when the sponsor conducts PK bioequivalence studies and efficacy and safety studies to demonstrate that the drug’s profile w ...
... Depending upon the nature and scope of efficacy studies required by FDA for 505(b)(2) drugs, an integrated summary of efficacy may be required. This requirement is more likely when the sponsor conducts PK bioequivalence studies and efficacy and safety studies to demonstrate that the drug’s profile w ...
Slide 1
... Failing to register as a Controlled Substance Prescribing Practitioner if you are a physician, or an osteopathic doctor who prescribes any controlled substance for the treatment of “chronic nonmalignant pain”. Chronic Nonmalignant Pain is defined as pain that is unrelated to cancer or rheumatoid art ...
... Failing to register as a Controlled Substance Prescribing Practitioner if you are a physician, or an osteopathic doctor who prescribes any controlled substance for the treatment of “chronic nonmalignant pain”. Chronic Nonmalignant Pain is defined as pain that is unrelated to cancer or rheumatoid art ...
McKesson Buys US Oncology: What Does This Further
... greater penetration of the market, particularly in areas of regional concentration of McKesson and US Oncology customers. The program will have greater success recruiting participating practices if McKesson is able to turn Pathways compliance into enhanced reimbursements from local payers. The succe ...
... greater penetration of the market, particularly in areas of regional concentration of McKesson and US Oncology customers. The program will have greater success recruiting participating practices if McKesson is able to turn Pathways compliance into enhanced reimbursements from local payers. The succe ...
Benefit vs. Risk: How CDER Approves New Drugs
... and drug advertising in medical journals was required to provide complete information to doctors— The "Elixir Sulfanilamide" tragedy of 1937 ensured enactthe risks, as well as the benefits. The ment the following year of the Federal Food, Drug, and amendments also required that Cosmetic Act. More th ...
... and drug advertising in medical journals was required to provide complete information to doctors— The "Elixir Sulfanilamide" tragedy of 1937 ensured enactthe risks, as well as the benefits. The ment the following year of the Federal Food, Drug, and amendments also required that Cosmetic Act. More th ...
Effect of acidic Ph. and heat on the degradation of omeprazole and
... formulations. Moreover the low aqueous solubility of OMZ, ~0.4% at 25 oC, is responsible for small dissolution rates and so low bioavailability [7]. OMZ is acid labile and a prodrug. It is converted into its active sulphenamide form by rearrangement under acidic conditions. It is a racemic mixture o ...
... formulations. Moreover the low aqueous solubility of OMZ, ~0.4% at 25 oC, is responsible for small dissolution rates and so low bioavailability [7]. OMZ is acid labile and a prodrug. It is converted into its active sulphenamide form by rearrangement under acidic conditions. It is a racemic mixture o ...
SPECTROPHOTOMETRIC DETERMINATION OF AMILORIDE IN BULK AND PHARMACEUTICAL FORMULATIONS Research Article
... were extracted quantitatively into chloroform and exhibiting absorption maxima at 590 nm and 420 nm with WFB and BCG respectively. The experimental factors affecting the development and stability of the ion-association complexes were studied and optimized. Such factors include pH, concentration of r ...
... were extracted quantitatively into chloroform and exhibiting absorption maxima at 590 nm and 420 nm with WFB and BCG respectively. The experimental factors affecting the development and stability of the ion-association complexes were studied and optimized. Such factors include pH, concentration of r ...
world preview 2014, outlook to 2020
... healthcare. Governments and payers will need to be more flexible in budget planning to accommodate these revolutionary new products, but do not expect easy discussions on products offering marginal benefits over generic products that are the current standard treatment of care. Surge in value of the ...
... healthcare. Governments and payers will need to be more flexible in budget planning to accommodate these revolutionary new products, but do not expect easy discussions on products offering marginal benefits over generic products that are the current standard treatment of care. Surge in value of the ...