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STV(])FES O!}{(])CJ(vq POqt£/ffl1flLS
STV(])FES O!}{(])CJ(vq POqt£/ffl1flLS

... to detailed investigation of their structure and pharmacological action. Some of the compounds were found to possess a definite physiological activity and later it was observed that the physiological activity of a compound is associated with a particular structural unit or group and if this structur ...
Public Assessment Report Scientific discussion Paroxetine Jubilant
Public Assessment Report Scientific discussion Paroxetine Jubilant

... The product specification includes tests for appearance, dimensions, identity (of the active substance as well as colorants), loss on drying, uniformity of dosage units, dissolution, related substances, assay and microbial quality. The release and shelf-life requirements/limits are identical, except ...
to our information package
to our information package

STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 
STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 

... standard  stock  solution  was  prepared  by  dissolving  250  mg  of  drug in 25 ml of 0.1 N NaOH, to give a concentration of 10 mg/ml.  For Ramipril,  standard stock solution  was prepared  by  dissolving  125mg of drug in 25 ml of 0.1 N NaOH, to give a concentration of 5  mg/ml.  Chromatographic  ...
1. Results of Operations (1) Analysis of Consolidated
1. Results of Operations (1) Analysis of Consolidated

RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS

... The standard stock solutions of TAM and TOL (1 mg/mL) were prepared separately by dissolving 50mg of each drug in 50mL of methanol. Several aliquots of these standard stock solutions were taken in different 10 mL volumetric flasks and diluted upto the mark with the mobile phase such that the final l ...
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... approval was required.17 The Florida Breckenridge plaintiff, the maker of a generic prescription hormonal replacement therapy drug, also sought a declaratory judgment against the maker of similar drug who had neglected to obtain FDA approval.18 In cases of the second type like Ethex and Florida Brec ...
International Journal of Pharmaceutical Research & Analysis
International Journal of Pharmaceutical Research & Analysis

... as a suitable method for the simultaneous estimation of mosapride and pantoprazole dosage form. The chromatographic conditions were optimized by changing the mobile phase composition. Different ratios were experimented to optimize the mobile phase. Finally, buffer and acetonitrile in the ratio 45:55 ...
Formulation and Evaluation of Terbutaline Sulphate Loaded
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... content increases, size of nanoparticles also increases. Particle size of designed formulations was in the range of 50-120 nm. Zeta potential of inhalation nanoparticles was determined using Zeta sizer and the obtained values were in the range 30.27 to 54.93mV and all the formulations carried slight ...
HERBAL TREATMENT FOR URINARY STONES
HERBAL TREATMENT FOR URINARY STONES

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The Manipulation of Data and Attitudes about ADHD: A
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... advertisement for a disease are more likely to bring up any concerns about a potential symptom with their doctor. The proponents of DTCA point out that, from a public health perspective, this is beneficial because increased disease awareness in the general population results in more people being tre ...
Updating the Beers Criteria for Potentially Inappropriate Medication
Updating the Beers Criteria for Potentially Inappropriate Medication

FDA Safety Reviews on Drugs, Biologics, and Vaccines: 2007–2013
FDA Safety Reviews on Drugs, Biologics, and Vaccines: 2007–2013

... defect, and other serious important medical events as well as unexpected events that may be potentially related to the product.8 For drugs, pediatric age is usually defined as birth through 16 years. Drug utilization data provide an estimate of patient exposure in the pediatric population and an idea ...
3. ACHIEVEment of policy goals
3. ACHIEVEment of policy goals

... territorial or federal plans. In most cases, patients share in the costs of reimbursed medicines through copayments or co-insurance, sometimes after meeting a deductible. The lack of protection against the risk of catastrophic out-of-pocket spending for drugs remains an issue for a small part of the ...
Alzheimer's Drugs Market, 2012 - 2017 Brochure
Alzheimer's Drugs Market, 2012 - 2017 Brochure

... Amongst other things, this report provides a detailed overview of the most promising pipeline drugs for the treatment of Alzheimer's. The market is desperate for a therapy that can slow or reverse disease progression. The next five years, from 2012-2017, will see the launch of many new drugs. Scope ...
PREPARATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF FINASTERIDE USING CO-PROCESSED EXCIPIENTS
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... Finasteride is a drug approved for the treatment of benign prostatic hyperplasia and male pattern baldness. It is a type II 5α-reductase inhibitor. 5αreductase is an enzyme that converts testosterone to dihydrotestosterone. Objective: The objective of this research was to formulate orodispersible ta ...
Spectrophotometric Determination of Drugs Using Iodine As Analytical Reagent  Sayaji Rao
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... dopamine D2 receptor antagonist. Its localization outside the blood –brain barrier and antiemetic properties has made it is a useful adjunct in therapy for Parkinson’s disease. There has been rehabilitated curiosity in antidopaminergic prokinetic agents, a 5-HT4 agonist, from the market. Domperidone ...
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR

... studied. The data obtained was used to derive simultaneous equations for determining the concentrations of the two drugs. Different parameters of study were optimized and the method was validated as per ICH guidelines. Results: PYR and DOX showed absorption maxima at 290 and 260 nm respectively. The ...
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... these tools, which aim to achieve standardisation in healthcare provision. In general most are based on evidence (see Chapter 7) and some have considerable ownership among the stakeholders expected to use them, which is an essential component of effective guidance. Their effectiveness in influencing ...
ALDEN, an Algorithm for Assessment of Drug Causality in Stevens
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... had been described as inconclusive exposures. Being more sensitive than a general method, ALDEN, which correlates well with case–control analysis results, can be considered a reference tool in SJS/TEN. Assessment of the causality of adverse events is important not only in the management of patients ...
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Pharmaceutical marketing

Pharmaceutical marketing, sometimes called medico-marketing or pharma marketing in some countries, is the business of advertising or otherwise promoting the sale of pharmaceuticals or drugs.Many countries have measures in place to limit advertising by pharmaceutical companies.Pharmaceutical company spending on marketing far exceeds that of its research budget. In Canada, $1.7 billion was spent in 2004 to market drugs to physicians; in the United States, $21 billion was spent in 2002. In 2005, money spent on pharmaceutical marketing in the United States was estimated at $29.9 billion with one estimate as high as $57 billion. When the U.S. numbers are broken down, 56% was free samples, 25% was pharmaceutical sales representative ""detailing"" (promoting drugs directly to) physicians, 12.5% was direct to user advertising, 4% on detailing to hospitals, and 2% on journal ads. There is some evidence that marketing practices can negatively affect both patients and the health care profession.
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