Suggestion from clinicians
... EPS was higher in studies where EPS prophylaxis was administered than in those in which it was not (24 % [95 % CI 13–43] vs. 7 % [95 % CI 3–15]; p = 0.01)” “Dysrhythmia, respiratory distress/arrest, neuroleptic malignant syndrome, and tardive dyskinesia were rarely associated with metoclopramide use ...
... EPS was higher in studies where EPS prophylaxis was administered than in those in which it was not (24 % [95 % CI 13–43] vs. 7 % [95 % CI 3–15]; p = 0.01)” “Dysrhythmia, respiratory distress/arrest, neuroleptic malignant syndrome, and tardive dyskinesia were rarely associated with metoclopramide use ...
Ergogenic Aids
... In the context of sport, an elgogenic aid can be broadly dejined as a technique or substance used for the purpose of enhancing performance. Ergogenic a i d have been classzj?ed as nutritional, pharmacologic, physiologic, or psychologic and range from use of accepted techniques such as carbohydrate l ...
... In the context of sport, an elgogenic aid can be broadly dejined as a technique or substance used for the purpose of enhancing performance. Ergogenic a i d have been classzj?ed as nutritional, pharmacologic, physiologic, or psychologic and range from use of accepted techniques such as carbohydrate l ...
Fever development in neuroleptic malignant syndrome during
... what dose was used the value of the fever was the same. The mechanism responsible for this is unknown, therefore, further research is required. ...
... what dose was used the value of the fever was the same. The mechanism responsible for this is unknown, therefore, further research is required. ...
Submission Guidelines for the CADTH Common Drug Review
... Common Drug Review (CDR) process. The Submission Guidelines for the CADTH Common Drug Review is a companion document to the Procedure for the CADTH Common Drug Review, a document that describes CDR procedures to be followed by all participants involved in the CDR process. The Submission Guidelines f ...
... Common Drug Review (CDR) process. The Submission Guidelines for the CADTH Common Drug Review is a companion document to the Procedure for the CADTH Common Drug Review, a document that describes CDR procedures to be followed by all participants involved in the CDR process. The Submission Guidelines f ...
O A
... The best results were obtained by using 16 nm as Δλ a scaling factor = 100 in order to diminish the error in reading the signal. Figures (3-5) show that it can be determined at 256.4 nm, 269.8 and 226.6 nm for D2, D3 and D4 respectively which correspond to the zero crossing points of its degradate. ...
... The best results were obtained by using 16 nm as Δλ a scaling factor = 100 in order to diminish the error in reading the signal. Figures (3-5) show that it can be determined at 256.4 nm, 269.8 and 226.6 nm for D2, D3 and D4 respectively which correspond to the zero crossing points of its degradate. ...
Enroflox Injection
... at 2.5 mg/kg. It should be administered intramuscularly (IM) as a single dose, followed by initiation of enrofloxacin tablet therapy. ...
... at 2.5 mg/kg. It should be administered intramuscularly (IM) as a single dose, followed by initiation of enrofloxacin tablet therapy. ...
the topical pain relief
... narcotic drugs, such as heroin or cocaine. It would appear that opioid drugs (oxycontin and vicodin) are the biggest problem because they contribute to three out of four of all prescription medication overdose deaths. Several reasons are responsible for this serious situation. First, these opioid dr ...
... narcotic drugs, such as heroin or cocaine. It would appear that opioid drugs (oxycontin and vicodin) are the biggest problem because they contribute to three out of four of all prescription medication overdose deaths. Several reasons are responsible for this serious situation. First, these opioid dr ...
Pharmacological treatment options for hypertrophic cardiomyopathy: high time for evidence
... b-Blockers represent the mainstay of therapy and have proved effective in patients with angina or dyspnoea on effort, particularly when associated with LVOT obstruction, and are often employed to reduce the prevalence of non-sustained ventricular arrhythmias.1,2 These beneficial effects are mediated ...
... b-Blockers represent the mainstay of therapy and have proved effective in patients with angina or dyspnoea on effort, particularly when associated with LVOT obstruction, and are often employed to reduce the prevalence of non-sustained ventricular arrhythmias.1,2 These beneficial effects are mediated ...
glumetza - U.S. Pharmacist
... Early metformin formulations required multiple daily doses because of adverse effects encountered with rapidrelease high single doses. Split multiple daily doses mitigated some of these problems, but required the patient to take two or more doses per day. Unfortunately, one of the most salient obsta ...
... Early metformin formulations required multiple daily doses because of adverse effects encountered with rapidrelease high single doses. Split multiple daily doses mitigated some of these problems, but required the patient to take two or more doses per day. Unfortunately, one of the most salient obsta ...
Volume 4, Supplement 1
... chemistry and biological advances in the fundamental and clinical study of antiviral diseases and their treatment. Areas covered include HIV, hepatitis B, hepatitis C and emerging viruses, co-infections, vaccines, animal models, pharmacology, microbicides, alternative therapies, viral dynamics and r ...
... chemistry and biological advances in the fundamental and clinical study of antiviral diseases and their treatment. Areas covered include HIV, hepatitis B, hepatitis C and emerging viruses, co-infections, vaccines, animal models, pharmacology, microbicides, alternative therapies, viral dynamics and r ...
APPLICATION CHECKLIST (ICH CTD)
... APPENDIX 3A APPLICATION CHECKLIST (ASEAN CTD – NDA and GDA) This Application Checklist should be used to ensure submission of a complete dataset in the ASEAN Common Technical Dossier (ACTD) format for NDA and GDA applications only. All documents required under Part I must be submitted in softcopy in ...
... APPENDIX 3A APPLICATION CHECKLIST (ASEAN CTD – NDA and GDA) This Application Checklist should be used to ensure submission of a complete dataset in the ASEAN Common Technical Dossier (ACTD) format for NDA and GDA applications only. All documents required under Part I must be submitted in softcopy in ...
Antibody–drug conjugates nonclinical support: from early to late
... may require different endpoints to address these questions [9,12,13] . During early drug discovery stage that involves candidate selection, optimization and early nonclinical assessments, the goal of ADC bioanalysis is to provide insights into the overall stability, safety and efficacy characterist ...
... may require different endpoints to address these questions [9,12,13] . During early drug discovery stage that involves candidate selection, optimization and early nonclinical assessments, the goal of ADC bioanalysis is to provide insights into the overall stability, safety and efficacy characterist ...
A bitter pill. Overview of ecstasy (MDMA, MDA) related
... (1998) suggest that the more serious complications (delirium, seizures, coma) are commoner when MDMA is consumed together with cocaine and amphetamines. In patients with a history negative for viral hepatitis and alcohol abuse, the occurrence of a toxic acute hepatitis has been reported. This potent ...
... (1998) suggest that the more serious complications (delirium, seizures, coma) are commoner when MDMA is consumed together with cocaine and amphetamines. In patients with a history negative for viral hepatitis and alcohol abuse, the occurrence of a toxic acute hepatitis has been reported. This potent ...
Accelerating antimalarial drug discovery through repositioning Holly
... the requirements for a Degree of Doctor of Philosophy, is a presentation of my own research work. Wherever contributions of others are involved, every effort is made to indicate this clearly with due reference to the literature and acknowledgement of collaborative research and discussions. The conte ...
... the requirements for a Degree of Doctor of Philosophy, is a presentation of my own research work. Wherever contributions of others are involved, every effort is made to indicate this clearly with due reference to the literature and acknowledgement of collaborative research and discussions. The conte ...
Phenylephrine Hydrochloride
... vasopressor in spinal anesthesia has been questioned because hypotension does not always occur during spinal anesthesia and treatment can readily be instituted if necessary. It has been suggested that vasopressors be administered prophylactically only in those cases in which a substantial decrease ...
... vasopressor in spinal anesthesia has been questioned because hypotension does not always occur during spinal anesthesia and treatment can readily be instituted if necessary. It has been suggested that vasopressors be administered prophylactically only in those cases in which a substantial decrease ...
PIRACETAM ñ AN OLD DRUG WITH NOVEL PROPERTIES?
... piracetam were reported almost 30 years ago but its mechanism of action was unknown for a long time. Piracetam was firstly tested in a model of ìcentral nystagmusî which was sensitive only to anticholinergic and antihistaminic drugs (2, 11). The current use of piracetam in vertigo might be related t ...
... piracetam were reported almost 30 years ago but its mechanism of action was unknown for a long time. Piracetam was firstly tested in a model of ìcentral nystagmusî which was sensitive only to anticholinergic and antihistaminic drugs (2, 11). The current use of piracetam in vertigo might be related t ...
Rehabilitation of Insectivorous Bats
... be willing to set up account. Dairies and fish farms use inexpensive microbiology labs and often are willing to share. You can get basic C & S for around $18.00. ...
... be willing to set up account. Dairies and fish farms use inexpensive microbiology labs and often are willing to share. You can get basic C & S for around $18.00. ...
Harm Reduction Journal
... activate the receptors since it seemed unlikely that cannabis receptors had evolved so people could partake of cannabis. In 1992, anandamide was discovered [8]. This lipid metabolite was the first ligand of an ever-expanding class of molecules known as endocannabinoids (internal marijuana-like compo ...
... activate the receptors since it seemed unlikely that cannabis receptors had evolved so people could partake of cannabis. In 1992, anandamide was discovered [8]. This lipid metabolite was the first ligand of an ever-expanding class of molecules known as endocannabinoids (internal marijuana-like compo ...
COMPOUNDING OPHTHALMIC LIQUIDS Y. Pramar, Ph.D
... 1. Prepare the solution in a manner similar to a parenteral preparation, using aseptic technique with sterile parenteral drug products as the solution ingredients, and packaging the solution in a clean, particle-free, sterile container. 2. Prepare the solution using non-sterile but high-quality ing ...
... 1. Prepare the solution in a manner similar to a parenteral preparation, using aseptic technique with sterile parenteral drug products as the solution ingredients, and packaging the solution in a clean, particle-free, sterile container. 2. Prepare the solution using non-sterile but high-quality ing ...
Simultaneous Inhibition of Fatty Acid Amide Hydrolase and
... NJ) per day after sessions. Forty-five mice used for brain dissection had continuous access to food (Teklad 7912; Harlan, Houston, TX) in the home cage. Water was continuously available in the home cage for all mice. Mice were maintained and experiments were conducted in accordance with the Universi ...
... NJ) per day after sessions. Forty-five mice used for brain dissection had continuous access to food (Teklad 7912; Harlan, Houston, TX) in the home cage. Water was continuously available in the home cage for all mice. Mice were maintained and experiments were conducted in accordance with the Universi ...
Expert peer review No.1 Agenda item 6.1: Tramadol
... combination with serotonergic agents, tramadol may induce the serotonin syndrome. The resulting hyperthermia could be potentially fatal. As well, few cases of severe respiratory depression associated with tramadol use have been reported but these were overdoses. Seizures ha ...
... combination with serotonergic agents, tramadol may induce the serotonin syndrome. The resulting hyperthermia could be potentially fatal. As well, few cases of severe respiratory depression associated with tramadol use have been reported but these were overdoses. Seizures ha ...
RP-HPLC Analysis of Aspirin - Indian Journal of Pharmaceutical
... Antifungal activities of different extracts of Millingtonia hortensis were investigated against various fungal pathogens. Methanol extract was found to have stronger activity than fluconazole against yeast like fungi: 4 fold against Candida krusei with 4 µg/ml minimal inhibitory concentration and 2 ...
... Antifungal activities of different extracts of Millingtonia hortensis were investigated against various fungal pathogens. Methanol extract was found to have stronger activity than fluconazole against yeast like fungi: 4 fold against Candida krusei with 4 µg/ml minimal inhibitory concentration and 2 ...
Review of cough and cold medicines in children
... Cough and cold medicines in children are used for acute or recurrent cough, usually without a definite diagnosis, and for cough and other symptoms believed by a parent to be due to the common cold. The brief discussion to follow refers to causes of these symptoms and to symptom patterns associated w ...
... Cough and cold medicines in children are used for acute or recurrent cough, usually without a definite diagnosis, and for cough and other symptoms believed by a parent to be due to the common cold. The brief discussion to follow refers to causes of these symptoms and to symptom patterns associated w ...
Sulodexide - Wiley Online Library
... with adjusted doses (international normalized ratio) of acenocoumarol. There were no differences in either clinical evolution of the disease or the number of venous recurrences over the course of the treatment period between groups. In the group treated with sulodexide there were no hemorrhagic comp ...
... with adjusted doses (international normalized ratio) of acenocoumarol. There were no differences in either clinical evolution of the disease or the number of venous recurrences over the course of the treatment period between groups. In the group treated with sulodexide there were no hemorrhagic comp ...