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Adverse effects
Adverse effects

... in many parts of the world. Areas of high risk for resistant parasites include Sub-Saharan Africa, Latin America, Oceania and some parts of South-East Asia. Chloroquine-resistant Plasmodium vivax is also reported. Any physician who is not familiar with the resistance pattern in the locality from whi ...
Antiarrhythmic Drugs
Antiarrhythmic Drugs

... – Impulse conduction – Combination of the two Results in change of heart rate or contraction of heart muscle in a way that is insufficient to maintain normal cardiac output To understand how antiarrhythmic drugs work, need to understand electrophysiology of normal contraction of heart ...
Pfizer to Acquire Biorexis to Access Novel Technology Platform and
Pfizer to Acquire Biorexis to Access Novel Technology Platform and

... these technologies have the potential to substantially improve patient tolerability as compared to other evolving protein therapeutic technologies. This new platform supports Pfizer's commitment to develop novel protein therapeutic agents where improved patient tolerability will lead to substantial ...
PHARMACEUTICAL ASPECTS OF NICORANDIL   
PHARMACEUTICAL ASPECTS OF NICORANDIL   

... component  of  the  system)  is  integrated  with  another  chemical  or  drug administration process to control rate, release site, or both. The  impetus  for  the  development  of  newer  or  novel  drug  delivery  systems  apart  from  therapeutic  efficacy.  Many  parameters  are  considered  fo ...
A1986E936300001
A1986E936300001

... My review was completed by November 1973 and just missed the deadline for the 1974 volume. However, it appeared at a fortunate time, encouraging others to explore this area when new pharmacological tools had become available. Subsequently, several drug companies developed novel anticonvulsant drugs ...
3 Perinatal Pharmacology
3 Perinatal Pharmacology

... the maternal plasma half-life of these drugs is very short, and less drug will ultimately reach the fetus. Conversely, some drugs have long-lived metabolites which can reach the fetus. For example, normeperidine, a metabolite of meperidine, is twice as toxic as the parent compound but only half as a ...


... The dissolution rate of selected prepared formulations F2 and F8 were compared with that of marketed conventional tablet. The F8 formulation shown prolonged release (86%) up to 12 hrs, but the marketed tablet released 97% of drug within 2.5 hrs. Further, to confirm the mechanism of drug release, F2 ...
Pharma 10
Pharma 10

... why do we have to do this modification for testosterone? Because usually it’s subjected to the first pass metabolic effect in the liver ,by adding alkyl group reduce it’s first path effect in the liver. 5) Patch : on that back or on the scrotum , there is good absorption in the scrotum skin ,also e ...
Diphenhydramine Hydrochloride Injection, USP
Diphenhydramine Hydrochloride Injection, USP

... overdosage may cause hallucinations, convulsions or death. As in adults, antihistamines may diminish mental alertness in pediatric patients. In the young pediatric patient, particularly, they may produce excitation. Use in the Elderly (approximately 60 years or older): Antihistamines are more likely ...
It`s Not Depression, It`s De` Hormones or Are your
It`s Not Depression, It`s De` Hormones or Are your

... Progestins, like Provera, do not resemble at all the bio-chemical structure of a woman’s natural progesterone. They cannot be taken during pregnancy without risking serious consequences for the fetus. Because of this many doctors also assume that bio-identical progesterone is toxic as well. A woman ...
Brief Bioinform-2015-Siavelis-bib_bbv048
Brief Bioinform-2015-Siavelis-bib_bbv048

... and compound enrichment). The main assumption is that a compound’s consistent anti-correlation with the disease reinforces its pharmacological significance. We then devised a back-loaded pipeline that emphasizes on structural comparisons, a common alternative in drug repurposing, based on an in-hous ...
Used Drugs to Treat Peptic Ulcer Disease
Used Drugs to Treat Peptic Ulcer Disease

... hepatic insufficiency. Elimination is through the urine. Headache is a common side effect. Electrocardiographic changes, such as prolongation of the QT interval, can occur with dolasetron; therefore, patients who may be at risk should receive this medication with caution. These drugs are costly. 3-S ...
Original article Pill burden in HIV infection: 20 years of experience
Original article Pill burden in HIV infection: 20 years of experience

... significantly from 0.5 ±1.7 in 1993 to 2.8 ±4.1 in 1995. It has remained between 2.0 and 2.6 since 1996; however, the yearly standard deviation has increased from 1.9 in 1990 to 4.5 in 2010. OTCs show similar trends albeit more modest and with much lower numbers of pills per day. By year 2000, most ...
Medical Assistant Pharmacology - Career and Technical Education
Medical Assistant Pharmacology - Career and Technical Education

...  physician’s signature blank – DAW or generic  refills  label prescription abbreviations Examine JCAHO’s website and find the DO NOT USE list for abbreviations that have been banned as part of JCAHO’s 2004 patient safety goals. Propose a reason for the banning of each abbreviation. interpret medi ...
Formulation and evaluation of delayed-onset extended
Formulation and evaluation of delayed-onset extended

... Several studies have demonstrated circadian rhythmicity for all body functions. Incidence of several cardiovascular events, like myocardial infarction, stroke and sudden cardiac death, also exhibit circadian rhythm (1, 2). These events are often observed early in the morning as the blood pressure (B ...
Metacam Risks in Cats
Metacam Risks in Cats

... Metacam Risks in Cats What is Metacam? Metacam® is the veterinary brand name for meloxicam, a non-steroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. This article deals with two versions: Metacam Solution for Injection (for cats) and Metacam Oral Suspension (for dogs). Met ...
RSI Drugs Powerpoint - Sites@Duke
RSI Drugs Powerpoint - Sites@Duke

... • At the completion of this module the learner should be able to: – Choose the appropriate induction agent and neuromuscular blocking agent for a given clinical situation – Calculate the appropriate dose of both induction agent and paralytic for a given patient and clinical situation – Understand re ...
SMALL RUMINANT ANESTHESIA
SMALL RUMINANT ANESTHESIA

... small ruminants for analgesia and muscle relaxation. Xylazine is sometimes used for premedication of sheep and goats but is not always necessary in the small ruminants and is not always well tolerated. Diazepam in combination with ketamine (6-7.5 mg/kg IV) is, in my opinion, the induction of choice. ...
phentermine HCl - Citius Pharmaceuticals
phentermine HCl - Citius Pharmaceuticals

... therapy with Suprenza and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. ...
D7A8D793D794D799D79C..
D7A8D793D794D799D79C..

... administered by oral capsule, targeting gastrointestinal and other solid tumors; (vii) RP101 currently subject to an option-to-acquire by RedHill, RP101 is a Phase II-stage first-in-class Hsp27 inhibitor, administered by oral tablet, targeting pancreatic and other gastrointestinal cancers; (viii) R ...
DEVELOPMENT AND EVALUATION OF CONTROLLED RELEASE
DEVELOPMENT AND EVALUATION OF CONTROLLED RELEASE

... including abdominal discomfort, constipation, diarrhea, dyspepsia, nausea and vomiting; these are usually mild and reversible but in some patient’s peptic ulceration and severe gastrointestinal bleeding may occur. Moreover, it requires frequent dosing due to its short elimination half-life of 3.9 hr ...
Treatments for Diabetes Mellitus
Treatments for Diabetes Mellitus

GenDrux: A guided supervised biomedical
GenDrux: A guided supervised biomedical

... recognition (NER) to extract information related to the disease-gene-drug nexus from an archive of relevant literature. This archive is generated using automated methods. This tool is freely accessible access by means of an Internet browser. The results generated by GenDrux are designed to alleviate ...
Uses
Uses

... diarrhoea and encourages overgrowth by resistant and undesirable bacteria (e.g. Staphylococcus aureus) and fungi (e.g. Candida sp.). – Interference with bone devolopment and brown staining of teeth occurs in the foetus and in children and thus these drugs should be avoid in pregnancy and in children ...
orodispersible_dosage_forms
orodispersible_dosage_forms

... low to allow for microbial growth. A major claim of the Zydis product is increased bioavailability compared to traditional tablets. Because of its dispersion and dissolution in saliva while still in the oral cavity, there can be a substantial amount of pregastric absorption from this formulation. Bu ...
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Prescription costs

Prescription costs are a common health care cost for many people and also the source of considerable economic hardship for some. These costs are sometimes referred to as out-of-pocket prescription costs, since for those with insurance, the total cost of their prescriptions may include expenses covered by a third party, such as an insurance company, as well as the individual. Out-of-pocket prescription costs include deductibles, co-payments, and upper limits in coverage.
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