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PHL 322 Antiepilepti..
PHL 322 Antiepilepti..

... high levels of phenytoin within minutes. • Fosphenytoin may also be administered intramuscularly (IM). • Phenytoin sodium should never be given IM because it can cause tissue damage and necrosis. • Fosphenytoin is the drug of choice and standard of care for IV and IM administration. • Due to sound-a ...
Memorandum 0861 ‘03  tIAR-3  I’130
Memorandum 0861 ‘03 tIAR-3 I’130

... Attached, please find a published review of scientific studies and other information which establish that this dietary ingredient, when used under the conditions suggested in the labeling of the dietary supplement, is reasonably expected to be safe. Threshold has contacted Takeda, one of the manufac ...
The incentive sensitization theory of addiction
The incentive sensitization theory of addiction

... the expression of such non-associative motivation processes as stress and pain. The contextual control over the expression of sensitization provides an additional mechanism that accounts for why addicts ‘want’ drugs most particularly when they are in drugassociated contexts. Finally, by spreading be ...
This PDF is a selection from an out-of-print volume from... of Economic Research
This PDF is a selection from an out-of-print volume from... of Economic Research

... that cocaine abuse is engendered, in part, by the drug's ability to act as a potent positive reinforcer in much the way that food, water, and sex act in that manner (Johanson and Schuster 1995). The reinforcing effect of cocaine is not unique to humans; it has been demonstrated in a wide variety of ...
WHO Guideline on Country Pharmaceutical Pricing Policies
WHO Guideline on Country Pharmaceutical Pricing Policies

... Development. Up to 90% of the population in developing countries purchase medicines through out-of-pocket payments, making medicines the largest family expenditure item after food. As a result, medicines, particularly those with higher costs, may be unaffordable for large sections of the global popu ...
Chapter 4 Power Point: Consciousness
Chapter 4 Power Point: Consciousness

... coffee, tea, most sodas, chocolate, and even many over-the-counter drugs. ...
Non-Steroidal Anti-Inflammatory Drugs (NSAID
Non-Steroidal Anti-Inflammatory Drugs (NSAID

... are NSAIDs and this places them at risk for over utilization and side effects. Moreover, there are multiple drug-drug interactions that can lead to potentially serious events.10 For instance, because NSAIDs inhibit platelet aggregation and prolong bleeding time, additive effects may be observed in p ...
adis drug evaluation Drugs 1998 Apr 55 (d): 563-584 0012
adis drug evaluation Drugs 1998 Apr 55 (d): 563-584 0012

... Patients in both groups achieved similar FPG and HbA1c levels at end-point (7.6 mmol/L and 7.6%). However, patients in the glimepiride plus insulin group required lower insulin dosages (49 vs 78 U/day) and achieved more rapid lowering of FPG after 2 and 4 weeks of treatment than the insulin/placebo ...
Safety of allopurinol compared with other urate
Safety of allopurinol compared with other urate

... using the patient, intervention, comparator, and outcome (PICO) approach. A librarian developed the search strategy. The following electronic databases were searched: The Cochrane Library (2014); MEDLINE (1950–January 2014); and EMBASE (1980–January 2014). The search was limited by language (English ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
HIGHLIGHTS OF PRESCRIBING INFORMATION

... there were patients who first developed a serum sodium <125 mmol/L more than one year after initiation of therapy. Most patients who developed hyponatremia were asymptomatic but patients in the clinical trials were frequently monitored and some had their Trileptal dose reduced, discontinued, or had ...
Republic of Palau - World Health Organization
Republic of Palau - World Health Organization

... FUNCTION IS IMPAIRED The use of drugs in patients with reduced renal function can give rise to problems for several reasons: -failure to excrete the drug or its metabolite may produce toxicity - sensitivity to some drugs is increased even if elimination is not impaired - many side effects are poorly ...
A Systematic Review and Meta-Analysis of the Efficacy of Piracetam
A Systematic Review and Meta-Analysis of the Efficacy of Piracetam

... More than 1,000 drugs have been tested in experimental stroke, with nearly 500 drugs having reported efficacy in animal models of focal cerebral ischaemia [1]. However, there is to date unequivocal evidence for the clinical efficacy of only 2 drugs – asprin [2] and tissue plasminogen activator [3]. ...
Community/Ambulatory Care Edition December 2008 Vol.7, Issue 12
Community/Ambulatory Care Edition December 2008 Vol.7, Issue 12

... high-alert medication, since it only adds to the potential for dangerous confusion. When branded generics are dispensed to patients, it is important that the generic name be listed on the prescription container label, along with the brand name, as necessary, whether Jantoven or Coumadin. Presently, ...
TYPE 2 DIABETES MELLITUS PREVENTION · prescriptions off
TYPE 2 DIABETES MELLITUS PREVENTION · prescriptions off

... specialty of medicine, but it may be more common in areas of medicine in which the patient population is less likely to be included in clinical trials (for example, pediatric, pregnant, or psychiatric patients). ...
NEUROMUSCULAR EFFECTS OF CISATRACURIUM IN MORBIDLY OBESE PATIENTS Z
NEUROMUSCULAR EFFECTS OF CISATRACURIUM IN MORBIDLY OBESE PATIENTS Z

... obesity is described as an excess of the ideal body weight (more than 160%), or BMI over 35 or 40. This condition leads to major health problems1,2. In our country, obesity is common, involving 26.4% of females and 38.5% of males. Obesity is associated with changes in body composition and functions ...
MS_Word ~ KB
MS_Word ~ KB

... oxidase inhibitors-MAOIs) and directly stimulating serotonin receptors (bromocriptine, lithium). Specific diagnostic criteria for serotonin toxicity have been identified. 31 32Clinically, serotonin toxicity may vary in severity and is usually self- limiting when appropriate supportive care has been ...
Graphene Oxide for Biomedical Applications
Graphene Oxide for Biomedical Applications

... biomedical applications revealed and confirmed the scope of its potential capabilities as biomaterial. GO alone and its modified form with different materials (surface functionalization, immobilization of nanoparticles and composite formation) also proved as a multifunctional candidate for medical b ...
MS_Word ~ 131 KB
MS_Word ~ 131 KB

... 60 mg SC and morphine 10 mg SC .3 Codeine caused the least spasm of the sphincter of Oddi, followed by pethidine and then morphine. Other studies directly measuring intrabiliary pressure have shown that parenteral pethidine and morphine produce a similar degree of increase in biliary pressure. 1 4 5 ...


... Specific diagnostic criteria for serotonin toxicity have been identified. 31 Clinically, serotonin toxicity may vary in severity and is usually self- limiting when appropriate supportive care has been instituted. Symptoms commonly resolve over 12 to 24 hours when the offending drugs are discontinued ...
Effects of Phenobarbital and carbon tetrachloride on liver enzymes
Effects of Phenobarbital and carbon tetrachloride on liver enzymes

... these rats. Bone disease could also not be suggestive compared to the results of ALP levels among these rats, which were at normal levels. Rats in group two also had increased elevated levels too, though rat 2a was within the normal levels but on the higher side. Rat 2b had elevated levels above the ...
Drugs of Abuse, Driving and Traffic Safety
Drugs of Abuse, Driving and Traffic Safety

... outcome measure of the driving test is the standard deviation of the lateral position (SDLP), i.e. the weaving of the car. Subjects are allowed to take over slower vehicles and are accompanied by a driving instructor with dual controls. In more than 60 on-the-road driving studies, dose-dependent imp ...
Cough and Angioedema in Patients Receiving Angiotensin
Cough and Angioedema in Patients Receiving Angiotensin

... switch to an angiotensin-II receptor blocker (ARB). ACEI-related angioedema does not have a specific treatment and the response to classical therapy is poor. (13) Fortunately, most cases are not severe and do not require treatment at all. In the OCTAVE trial, 86 out of 12,557 patients receiving enal ...
Click here for handout
Click here for handout

... remains difficult, since more than 85 % of physicians are unaware of the serotonin syndrome as a clinical diagnosis. ...
Intraspinal Drug Infusion for Chronic Pain
Intraspinal Drug Infusion for Chronic Pain

... delivery BEFORE proceeding with a trial Goals defined on a case-by-case basis Theoretically, the trial should approximate as closely as possible the conditions of long-term therapy IT drug delivery is represents only a SINGLE element in overall long-term pain management for a given patient ...
Card_dyslipidemia diabetes2 ER.indd
Card_dyslipidemia diabetes2 ER.indd

... More than 60% of type 2 diabetic subjects in the Eastern Mediterranean Region have some degree of dyslipidaemia. More than 40% of type 2 diabetic individuals have hypercholesterolemia and a further 23% have hypertriglyceridaemia and/or a low level of HDL cholesterol. In contrast, <25% of non-diabeti ...
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Prescription costs

Prescription costs are a common health care cost for many people and also the source of considerable economic hardship for some. These costs are sometimes referred to as out-of-pocket prescription costs, since for those with insurance, the total cost of their prescriptions may include expenses covered by a third party, such as an insurance company, as well as the individual. Out-of-pocket prescription costs include deductibles, co-payments, and upper limits in coverage.
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