Controlled drug release
... We seek to maintain drug conc in blood within the Therapeutic range during therapy. This requires not only the selection of an appropriate daily dose, the drug must also be given with sufficient frequency so as to minimize the range of blood conc that are produced. The ratio of max to minimum drug c ...
... We seek to maintain drug conc in blood within the Therapeutic range during therapy. This requires not only the selection of an appropriate daily dose, the drug must also be given with sufficient frequency so as to minimize the range of blood conc that are produced. The ratio of max to minimum drug c ...
M.Sc.(PHARMACEUTICAL CHEMISTRY) PART
... answer / objective type questions, which will cover the entire syllabus uniformly and will carry 28 marks (2 marks each). INSTRUCTIONS FOR THE CANDIDATES: ...
... answer / objective type questions, which will cover the entire syllabus uniformly and will carry 28 marks (2 marks each). INSTRUCTIONS FOR THE CANDIDATES: ...
Antifungal drugs
... Pharmacokinetics and administration -F(oral): » 50% (micronization of the drug and a high-fat food favor oral absorption) -Distribution is mainly in keratinized tissues where the drug is tightly bound and where it can be detected 4-8 hours after oral administration. Concentration in other tissues ...
... Pharmacokinetics and administration -F(oral): » 50% (micronization of the drug and a high-fat food favor oral absorption) -Distribution is mainly in keratinized tissues where the drug is tightly bound and where it can be detected 4-8 hours after oral administration. Concentration in other tissues ...
Carolinas HealthCare System: Medication Management for Older
... Case 2: Mr. Jones 3) What physiologic change associated with normal aging may affect Mr. Jones’ clinical response to medications? c) Prolonged half-life of lipid-soluble drugs due to a higher relative composition of body fat compared to younger individuals ...
... Case 2: Mr. Jones 3) What physiologic change associated with normal aging may affect Mr. Jones’ clinical response to medications? c) Prolonged half-life of lipid-soluble drugs due to a higher relative composition of body fat compared to younger individuals ...
Variation in Drug Responsiveness
... c. Genetic factors also can play an important role in altering the number or function of specific receptors e.g a specific genetic variant of 2C-adrenoceptor when inherited with 1-adrenoceptor greatly increased risk of CHF which can be reduced by early intervention using antagonist drugs Pharma ...
... c. Genetic factors also can play an important role in altering the number or function of specific receptors e.g a specific genetic variant of 2C-adrenoceptor when inherited with 1-adrenoceptor greatly increased risk of CHF which can be reduced by early intervention using antagonist drugs Pharma ...
It`s not just marijuana anymore: A review of illicit drugs. Ahna Brutlag
... The exposure of animals to illicit drugs through inadvertent or intentional action can result in serious consequences. Each week Pet Poison Helpline receives calls where illicit drug exposure is confirmed or strongly suspected in cats and dogs. Understandably, the confirmation of illicit drug exposu ...
... The exposure of animals to illicit drugs through inadvertent or intentional action can result in serious consequences. Each week Pet Poison Helpline receives calls where illicit drug exposure is confirmed or strongly suspected in cats and dogs. Understandably, the confirmation of illicit drug exposu ...
DIA 2013 Annual Meeting - Alliance for Safe Biologic Medicines
... • Switching a patient between biological products – whether biosimilar or simply biologics in the same class – could have unwanted and unintended consequences, including an unwanted immune response. • Therefore, biologic drug shortages could create additional risk for patients. ...
... • Switching a patient between biological products – whether biosimilar or simply biologics in the same class – could have unwanted and unintended consequences, including an unwanted immune response. • Therefore, biologic drug shortages could create additional risk for patients. ...
Sedative-HypnoticsJGeneral Depressants alcohol (ethyl alcohol, or
... Note: A number of these substances are classified as Schedule I drugs and therefore are not legally available. Hence, their trade names, referred to here, are those that were used when they were sold as prescription drugs; they are not currently manufactured under these trade names. ...
... Note: A number of these substances are classified as Schedule I drugs and therefore are not legally available. Hence, their trade names, referred to here, are those that were used when they were sold as prescription drugs; they are not currently manufactured under these trade names. ...
for the lecture
... Rapid death of TB XDR patients at Tugela Ferry: 52/53 died, half within 16 days ...
... Rapid death of TB XDR patients at Tugela Ferry: 52/53 died, half within 16 days ...
Antimicrobial Agents
... • 1940 Florey and Chain mass produce penicillin for war time use, becomes available to the public. • 1935 Sulfa drugs discovered • 1943 Streptomycin discovered • Western civilization fundamentally changed ...
... • 1940 Florey and Chain mass produce penicillin for war time use, becomes available to the public. • 1935 Sulfa drugs discovered • 1943 Streptomycin discovered • Western civilization fundamentally changed ...
Institutional Review Board
... 2. If the drug that is undergoing investigation is lawfully marketed as a prescription drug product, the investigation is not intended to support a significant change in the advertising for the product; 3. The investigation does not involve a route of administration or dosage level or use in a pati ...
... 2. If the drug that is undergoing investigation is lawfully marketed as a prescription drug product, the investigation is not intended to support a significant change in the advertising for the product; 3. The investigation does not involve a route of administration or dosage level or use in a pati ...
Document
... Soon after (until May 1998) Bayer received 6 SADRs of cerivastatin associated rhabdomyolysis in patients also taking gemfibrozil. This was followed by label update – rhabdomyolysis warning. ...
... Soon after (until May 1998) Bayer received 6 SADRs of cerivastatin associated rhabdomyolysis in patients also taking gemfibrozil. This was followed by label update – rhabdomyolysis warning. ...
Synthetic Opioids Did you know?
... A 27 year old man with a history of heroin abuse was found unresponsive and apneic in bed. Next to him were three small bags containing a white powder and labeled “100 mg PFBF”. There was no response to 2 mg naloxone (intranasal) given by EMS, but he woke up and became agitated after a second 2 mg d ...
... A 27 year old man with a history of heroin abuse was found unresponsive and apneic in bed. Next to him were three small bags containing a white powder and labeled “100 mg PFBF”. There was no response to 2 mg naloxone (intranasal) given by EMS, but he woke up and became agitated after a second 2 mg d ...
NEW Psychoactive DRUGS www.mycrew.org.uk
... MDAI is similar to MDMA but less potent and with less stimulant effects and therefore MDAI is commonly found mixed with stimulant NPS in branded packets. It can make you feel a rush through your body and head, often experienced as a tingling sensation and it also increases your heart rate and blood ...
... MDAI is similar to MDMA but less potent and with less stimulant effects and therefore MDAI is commonly found mixed with stimulant NPS in branded packets. It can make you feel a rush through your body and head, often experienced as a tingling sensation and it also increases your heart rate and blood ...
Pharmacology Update 1999 - Distance Learning Center for
... Initiation of Substance Use (Incidence, or First-Time Use) The illicit drug use categories with the largest number of recent initiates among persons aged 12 or older were nonmedical use of pain relievers (2.2 million) and marijuana use (2.1 million). These estimates are not significantly differen ...
... Initiation of Substance Use (Incidence, or First-Time Use) The illicit drug use categories with the largest number of recent initiates among persons aged 12 or older were nonmedical use of pain relievers (2.2 million) and marijuana use (2.1 million). These estimates are not significantly differen ...
Brand-Name vs Generic Finasteride Jan-Feb 2016
... brand-name medications. Branded drugs are priced higher than the generic drugs. Therefore, the sales commission is much higher for everyone in the supply chain. Since the generics are priced considerably lower, the revenue earned by everyone in the supply chain is lower. Cost differences can be subs ...
... brand-name medications. Branded drugs are priced higher than the generic drugs. Therefore, the sales commission is much higher for everyone in the supply chain. Since the generics are priced considerably lower, the revenue earned by everyone in the supply chain is lower. Cost differences can be subs ...
Imatinib
... blast crisis. Dose increases from 400 mg to 600 mg or 800 mg in patients with chronic phase disease, or from 600 mg to a maximum of 800 mg (given as 400 mg twice daily) in patients with accelerated phase or blast crisis may be considered in the absence of severe adverse drug reaction and severe nonl ...
... blast crisis. Dose increases from 400 mg to 600 mg or 800 mg in patients with chronic phase disease, or from 600 mg to a maximum of 800 mg (given as 400 mg twice daily) in patients with accelerated phase or blast crisis may be considered in the absence of severe adverse drug reaction and severe nonl ...
Protein Data Bank Advisory Committee
... • collects triglycerides from very low density or low density lipoproteins (VLDL or LDL) and exchanges them for cholesteryl esters from high density lipoproteins (and vice versa) • A long tunnel with two major binding sites. Docking studies suggest that it possible that torcetrapib binds to both of ...
... • collects triglycerides from very low density or low density lipoproteins (VLDL or LDL) and exchanges them for cholesteryl esters from high density lipoproteins (and vice versa) • A long tunnel with two major binding sites. Docking studies suggest that it possible that torcetrapib binds to both of ...
Drug Identification, continued
... ® Any drugs taken in excessive amounts and causes illness or death is classified as a poison ® Legal drugs that are taken solely for pleasure are considered illicit drugs. ® “Controlled substances” are drugs that are restricted by law. ® The Controlled Substances Act is a law that was enacted in 197 ...
... ® Any drugs taken in excessive amounts and causes illness or death is classified as a poison ® Legal drugs that are taken solely for pleasure are considered illicit drugs. ® “Controlled substances” are drugs that are restricted by law. ® The Controlled Substances Act is a law that was enacted in 197 ...
Understanding Drug and Alcohol Abuse and Addiction
... Neuroadaptation • Tolerance – need for increased amounts of the substance to achieve intoxication or desired effect – markedly diminished effect with continued use of the same amount of the substance ...
... Neuroadaptation • Tolerance – need for increased amounts of the substance to achieve intoxication or desired effect – markedly diminished effect with continued use of the same amount of the substance ...
Protein Data Bank Advisory Committee
... • collects triglycerides from very low density or low density lipoproteins (VLDL or LDL) and exchanges them for cholesteryl esters from high density lipoproteins (and vice versa) • A long tunnel with two major binding sites. Docking studies suggest that it possible that torcetrapib binds to both of ...
... • collects triglycerides from very low density or low density lipoproteins (VLDL or LDL) and exchanges them for cholesteryl esters from high density lipoproteins (and vice versa) • A long tunnel with two major binding sites. Docking studies suggest that it possible that torcetrapib binds to both of ...
Drug Therapy for Older Adults
... concomitant diseases, medications and nutritional status than by aging alone. New drugs should be avoided/ used cautiously until their full effects in older persons are known. ...
... concomitant diseases, medications and nutritional status than by aging alone. New drugs should be avoided/ used cautiously until their full effects in older persons are known. ...
A new international, multicenter study has found that incretin
... noted the pancreatic cancer risk (but which didn't specifically investigate it) were limited in a number of ways including, small sample sizes, low duration time follow-ups and a low number of specific incretin-based drugs. The findings of this new study suggests that when compared to sulfonylureas, ...
... noted the pancreatic cancer risk (but which didn't specifically investigate it) were limited in a number of ways including, small sample sizes, low duration time follow-ups and a low number of specific incretin-based drugs. The findings of this new study suggests that when compared to sulfonylureas, ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.