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B I S TV!
B I S TV!

... 2010, a meta-analysis was performed to critically evaluate the evidence for the effectiveness or efficacy of botanical treatments in reducing skin aging and wrinkling [Hunt, 2010]. Of 36 potentially relevant studies, 11 trials of botanical extracts for reducing skin wrinkling and the appearance of ...
The oral delivery of macromolecules
The oral delivery of macromolecules

... 4) maintenance of the biological effects of the drug. The supramolecular complex formed by the Carriers and certain therapeutic compounds has applications in the delivery of drugs through other biological membranes, including intestinal, nasal, buccal, sublingual, subcutaneous and intra-ocular membr ...
The Role of Neuroimaging in Clinical Trials and Drug Discovery In
The Role of Neuroimaging in Clinical Trials and Drug Discovery In

... Is blockade of the SERT and the norepinephrine transporter (NET) the therapeutic principle of clomipramine (and of the TCAs in general)? ...
What`s New on the Streets
What`s New on the Streets

... Methamphetamine Methamphetamine is a powerful, highly addictive stimulant that affects the central nervous system. Also known as meth, chalk, ice, and crystal, among many other terms, it takes the form of a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol ...
Potentially hazardous drug interactions with psychotropics
Potentially hazardous drug interactions with psychotropics

... more likely to take several drugs concurrently, are at greater risk of an adverse drug interaction than younger people. This is because of effects of ageing on organs that deal with the metabolism and excretion of drugs, notably the liver and kidneys. Other vulnerable groups include polydrug misuser ...
Biosimilar Strategy at MedImpact
Biosimilar Strategy at MedImpact

... indicated as last-line treatment providing debatable value. Often, ongoing studies of these cancer agents earlier in disease progression show greater value. These drugs then sometimes receive indications for use higher in the treatment pathway. Coverage of these high-cost specialty medications for w ...
Technical Paper III - Pharmacy - Bhutan Civil Service Examinations
Technical Paper III - Pharmacy - Bhutan Civil Service Examinations

... 3. What are the signs and symptoms of seizures? What type of seizure is consistent with Dema’s symptoms? (7) 4. Comment on the pharmacological management of epilepsy. What is the mode of action of valproate and what side effects are associated with its use? (10) 5. Give three examples of drugs recom ...
09107sgp05
09107sgp05

... blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra). Compound Discovery: Sildenafil was synthesized by a group of pharmaceutical chemists wor ...
Bayer Buys Rights to Market GWP`s Cannabis
Bayer Buys Rights to Market GWP`s Cannabis

... acid were well known but “its success was diminished by the irritation and damage it caused to the moist membranes lining the mouth, gullet and stomach.” It was not until the late 1890s that Bayer chemist Felix Hofmann found a simple way to make salicylic acid in a less irritating form by adding an ...
Drug Therapy of Parkinsonism
Drug Therapy of Parkinsonism

... bromocriptine and pergolide than with levodopa. * Like levodopa, brompcriptine and pergolide are contraindicated in patients with history of psychosis. * Pramipexole: Recently introduced dopamine receptor agonists; they are not ergot derivatives. # They are presently considered to be first-line drug ...
Drugs Used to Treat High Blood Pressure
Drugs Used to Treat High Blood Pressure

... lowest strength available was a 25 milligram tablet that had to be broken in half to achieve the 12.5 milligram dose. There is now a 12.5 milligram capsule of hydrochlorothiazide available with the brand name Microzide. There is growing evidence that thiazide diuretics, such as hydrochlorothiazide, ...
drug
drug

... • Disintegration and dissolution are the two main processes for the oral administered drugs before the absorption process. • The absorption rate and absorption ratio of the orally administered drugs are closely related with the above two parameters. ...
ESTIMATION OF TROXIPIDE IN TABLET DOSAGE FORM BY RP-HPLC Research Article
ESTIMATION OF TROXIPIDE IN TABLET DOSAGE FORM BY RP-HPLC Research Article

... ulcers.2-4. It has been postulated that Troxipide's mucosal protective effect in gastric ulcer and gastritis is exerted via the inhibition of inflammatory responses and neutrophil-mediated5 mucosal injury. As neutrophils are thought to be involved in the pathogenesis of H. pylori-mediated mucosal in ...
Antidepressant
Antidepressant

... serotonin and norepinephrine. These agents may be effective in treating depression in patients in whom SSRIs are ineffective, in addition to treat the painful symptoms that associate depression such as backache and muscle aches. The SNRIs, unlike the tricyclic antidepressants, have little activity a ...
co-guide
co-guide

... and prolongs the life1. Despite the positive therapeutic effects, antiretroviral therapy (ART) may cause undesirable adverse effects. Adverse drug reactions (ADRs) are the most common reasons for ART interruption among HIV infected patients and over 25% of these patients discontinue ART within the f ...
Lecture 9 - Abercrombie 10/27 Notes
Lecture 9 - Abercrombie 10/27 Notes

... Inhalation - Very large surface area and high degree of vascularization of lungs. Lungs receive half of blood pumped from heart. Most effective absorptive area of body. Gases are almost always small molecules of high lipid solubility and are almost instantaneously absorbed when inhaled. Aerosol prep ...
Report on New Patented Drugs — Olmetec Application of the
Report on New Patented Drugs — Olmetec Application of the

... The publication of Summary Reports is part of the PMPRB’s commitment to make its price review process more transparent. Where comparators and dosage regimens are referred to in the Summary Reports, they have been selected by the HDAP for the purpose of carrying out the PMPRB’s regulatory mandate, wh ...
M.Pharm. Dissertation protocol
M.Pharm. Dissertation protocol

... The present work is aimed to design and evaluate the stavudine gellan gum microbeads by ionotropic gelation technique as a sustained release system. It is widely used as a antiviral agent. The drug is practically soluble in water. Hence, the main aim of the present study is to develop a sustained dr ...
ANS Review+Qs
ANS Review+Qs

... Monoamine oxidase inhibitors (phenelzine) ...
International and Canadian standards
International and Canadian standards

... US Food and Drug Administration (FDA) Regulations ...
Short- and Long-Term Effects and Withdrawal Symptoms
Short- and Long-Term Effects and Withdrawal Symptoms

... strength, frequency or manner that causes damage to the physical or mental functioning of an individual, it becomes ‘drug abuse’. Any type of drug can be abused; drugs with medical uses can also be abused. Illegal drugs like brown sugar and ganja have no medical use at all. To use them, is to abuse ...
ALDEN, an Algorithm for Assessment of Drug Causality in Stevens
ALDEN, an Algorithm for Assessment of Drug Causality in Stevens

... necrolysis (TEN) are usually drug related and are characterized by a high death rate. The process of epidermal necrolysis (EN) results in extensive blisters and detachment of skin and mucous membranes.8 SJS and TEN are two forms of EN, ­differing only with respect to the amount of skin detachment re ...
biotransformation
biotransformation

...  Most common phase II reaction. Catalyzed by glucuronyl transferase in S.E.R. in liver, kidney and other tissues in presence of uridie diphosphate glucuronate (DP-G) as glucuronate donor to form glucaronides which are: 1) Generally inactive  But morphine glucuronide is more active than morphine as ...
Adverse reactions to drugs, BMJ 1998
Adverse reactions to drugs, BMJ 1998

... toxic metabolite to bind to proteins, resulting in hepatocellular damage.19 The use of Nacetylcysteine to treat paracetamol overdose shows that elucidation of the mechanism of drug toxicity can lead to the development of rational treatments that will prevent toxicity. Alcoholic patients show increas ...
Outsourcing human tissue research_Outsourcing Pharma
Outsourcing human tissue research_Outsourcing Pharma

... and delivery of in vitro human data. We have a dedicated team of scientists that has significant expertise in both human tissue research and drug discovery, and who work closely with customers to provide professionally managed research support, with as much consultation and flexibility in scientific ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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