Formulation and in vitro Evaluation of Alfuzosin Extended Release
... in tablets prepared by direct compression. The amounts of both polymers were taken as independent variables for the 32 Factorial design. The percent drug releases at 1, 6, 12 and 20 h were selected as responses. The main effect and interaction terms were quantitatively evaluated using mathematical m ...
... in tablets prepared by direct compression. The amounts of both polymers were taken as independent variables for the 32 Factorial design. The percent drug releases at 1, 6, 12 and 20 h were selected as responses. The main effect and interaction terms were quantitatively evaluated using mathematical m ...
Placebo Effect
... functional activity, usually by depressing the nervous system. And it have various modes of action and effects. Some are primarily used medically to relieve emotion stress, anxiety, and tension; others induce sleep, and still others are used to relieve pain ...
... functional activity, usually by depressing the nervous system. And it have various modes of action and effects. Some are primarily used medically to relieve emotion stress, anxiety, and tension; others induce sleep, and still others are used to relieve pain ...
DUEXIS® (ibuprofen 800mg/famotidine 26.6mg) oral tablet
... documentation of failure / ineffectiveness of concurrent use (each ingredient used at the same time) of individual generic components. When the drug in question is a low dose formulation, there must be documentation of failure / ineffectiveness of low dose generic formulation. Adverse Drug Event: Al ...
... documentation of failure / ineffectiveness of concurrent use (each ingredient used at the same time) of individual generic components. When the drug in question is a low dose formulation, there must be documentation of failure / ineffectiveness of low dose generic formulation. Adverse Drug Event: Al ...
EVALUATION OF TAMARIND SEED POLYSACCHARIDE AS ABIODEGRADABLE CARRIER FOR COLON SPECIFIC DRUG DELIVERY
... drug delivery. Hence an attempt was made to develop matrix tablet based formulation using TSP which protects the drug in upper GIT and release the major amount of drug in colon due to degradation by bacterial enzymes. The matrix tablets were prepared by wet granulation techniqu ...
... drug delivery. Hence an attempt was made to develop matrix tablet based formulation using TSP which protects the drug in upper GIT and release the major amount of drug in colon due to degradation by bacterial enzymes. The matrix tablets were prepared by wet granulation techniqu ...
Insomnia - Consumer Reports
... Sleeping pills should be taken more judiciously and less often than appears to be the current pattern of use by millions of people in the U.S. There are two main reasons for this advice: • People with only mild insomnia may be relying too heavily on pills and not trying to address their sleep proble ...
... Sleeping pills should be taken more judiciously and less often than appears to be the current pattern of use by millions of people in the U.S. There are two main reasons for this advice: • People with only mild insomnia may be relying too heavily on pills and not trying to address their sleep proble ...
Guidelines
... Arterakine tablets would have contributed to the bioinequivalence of the two formulations, after adjustment for drug content, the Cmax and AUC of both drugs were still outside the acceptance range of 80 to 125% (data not shown). …………... Because the bioavailability of dihydroartemisinin and piperaqui ...
... Arterakine tablets would have contributed to the bioinequivalence of the two formulations, after adjustment for drug content, the Cmax and AUC of both drugs were still outside the acceptance range of 80 to 125% (data not shown). …………... Because the bioavailability of dihydroartemisinin and piperaqui ...
PHAR 7633 Chapter 12 Physical-Chemical Factors
... For a drug to cross a membrane barrier it must normally be soluble in the lipid material of the membrane to get into membrane and it has to be soluble in the aqueous phase as well to get out of the membrane. Many drugs have polar and non-polar characteristics or are weak acids or bases. For drugs wh ...
... For a drug to cross a membrane barrier it must normally be soluble in the lipid material of the membrane to get into membrane and it has to be soluble in the aqueous phase as well to get out of the membrane. Many drugs have polar and non-polar characteristics or are weak acids or bases. For drugs wh ...
Pharmaceutical Dosage Forms
... Pharmaceutical preparations compounded individually These PP are compounded individually for a particular patient according to the physician's prescription in a pharmacy licensed for compounding In contrast to the past, they are used rather rarely and mostly in specific situations It is highly ...
... Pharmaceutical preparations compounded individually These PP are compounded individually for a particular patient according to the physician's prescription in a pharmacy licensed for compounding In contrast to the past, they are used rather rarely and mostly in specific situations It is highly ...
orodispersible_dosage_forms
... low to allow for microbial growth. A major claim of the Zydis product is increased bioavailability compared to traditional tablets. Because of its dispersion and dissolution in saliva while still in the oral cavity, there can be a substantial amount of pregastric absorption from this formulation. Bu ...
... low to allow for microbial growth. A major claim of the Zydis product is increased bioavailability compared to traditional tablets. Because of its dispersion and dissolution in saliva while still in the oral cavity, there can be a substantial amount of pregastric absorption from this formulation. Bu ...
RDRC Application. - Stony Brook Research
... b. Source of radioactive drug (e.g., SBU lab, non-SBU lab, commercial supplier): 4. Preparation: Commercial products must be supported with either an NDC number or a certificate of analysis which states that materials are intended for human use. For all other materials: a. Provide details of synthes ...
... b. Source of radioactive drug (e.g., SBU lab, non-SBU lab, commercial supplier): 4. Preparation: Commercial products must be supported with either an NDC number or a certificate of analysis which states that materials are intended for human use. For all other materials: a. Provide details of synthes ...
CASE 11 - Caangay
... Anthelminthic Drugs MOA: 1) Paralysis worm 2) Damaging its cuticle, leading to partial digestion or to rejection by immune mechanims 3) Interfere with metabolism of the worm ...
... Anthelminthic Drugs MOA: 1) Paralysis worm 2) Damaging its cuticle, leading to partial digestion or to rejection by immune mechanims 3) Interfere with metabolism of the worm ...
Chapter-2 Review of Literature
... The bioavailability of ontazolast was significantly and substantially enhanced by all of the lipid-based formulations. Abu.T.M.Serajuddin et al. (2008) investigated the solution of a poorly water-soluble drug in a liquid lipid–surfactant mixture, which served as a microemulsion preconcentrate, was c ...
... The bioavailability of ontazolast was significantly and substantially enhanced by all of the lipid-based formulations. Abu.T.M.Serajuddin et al. (2008) investigated the solution of a poorly water-soluble drug in a liquid lipid–surfactant mixture, which served as a microemulsion preconcentrate, was c ...
renal impairment studies in early development services
... diabetes, hypertension and metabolic disorders (eg, increases in urea, lipids, etc). That is why using narrow eligibility criteria could jeopardize patient enrollment and negatively impact timelines, as well as the successful conduct of the study. By following the appropriate criteria, PRA’s PPS gro ...
... diabetes, hypertension and metabolic disorders (eg, increases in urea, lipids, etc). That is why using narrow eligibility criteria could jeopardize patient enrollment and negatively impact timelines, as well as the successful conduct of the study. By following the appropriate criteria, PRA’s PPS gro ...
Profile: Oxycodone - CESAR
... theft, doctor shopping (going from doctor to doctor to collect multiple prescriptions), organized drug rings that divert and sell the drugs, and foreign diversion and smuggling. Unscrupulous doctors, dentists, and pharmacists have also prescribed and sold controlled substances for illicit use. ...
... theft, doctor shopping (going from doctor to doctor to collect multiple prescriptions), organized drug rings that divert and sell the drugs, and foreign diversion and smuggling. Unscrupulous doctors, dentists, and pharmacists have also prescribed and sold controlled substances for illicit use. ...
validated spectroscopic method for estimation of frovatriptan
... for quantitative estimation of frovatriptan succinatein bulk drug and pharmaceutical dosage form. Frovatriptan succinate is dissolved in distilled water and the resulting solution was then scanned in the UV range (200-400nm) in a 10 mm quartz cell in a double beam UV spectrophotometer. The λmax of F ...
... for quantitative estimation of frovatriptan succinatein bulk drug and pharmaceutical dosage form. Frovatriptan succinate is dissolved in distilled water and the resulting solution was then scanned in the UV range (200-400nm) in a 10 mm quartz cell in a double beam UV spectrophotometer. The λmax of F ...
formulation, evaluation and in vitro dissolution performance of
... chains. This relaxation effect, in turn, increases distance among the polymeric chains. In hydrated polymer the molecular volume of polymer is increased that reduces the free volume due to the presence of microspores, which is observed clearly as shift in the drug release mechanism. Other researcher ...
... chains. This relaxation effect, in turn, increases distance among the polymeric chains. In hydrated polymer the molecular volume of polymer is increased that reduces the free volume due to the presence of microspores, which is observed clearly as shift in the drug release mechanism. Other researcher ...
Pharmacology
... •Safety data of different time courses •Short and long-term administration •Animals on long-term administration are monitored for the development of cancer ...
... •Safety data of different time courses •Short and long-term administration •Animals on long-term administration are monitored for the development of cancer ...
ARA Prescriber`s Information on Medications for Rheumatic
... Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible. Category D: Drugs which have caused, are suspected to have caused or may be expe ...
... Category C: Drugs which, owing to their pharmacological effects, have caused or may be suspected of causing, harmful effects on the human foetus or neonate without causing malformations. These effects may be reversible. Category D: Drugs which have caused, are suspected to have caused or may be expe ...
Parkinsonism-b
... (A) It should not be administered to patients taking antimuscarinic drugs (B) Effectiveness in Parkinson's disease requires its metabolic conversion to an active metabolite (C) The drug is contraindicated in patients with a history of psychosis (D) The drug should not be administered to patients alr ...
... (A) It should not be administered to patients taking antimuscarinic drugs (B) Effectiveness in Parkinson's disease requires its metabolic conversion to an active metabolite (C) The drug is contraindicated in patients with a history of psychosis (D) The drug should not be administered to patients alr ...
Document
... 4) Both ointments and creams are semisolid emulsions of oil and water. In ointments, the main ingredient is water; in creams, the main ingredient is oil. Answer: FALSE Explanation: The main ingredient in ointments is oil. The main ingredient in creams is water. 5) Specially formulated ointments and ...
... 4) Both ointments and creams are semisolid emulsions of oil and water. In ointments, the main ingredient is water; in creams, the main ingredient is oil. Answer: FALSE Explanation: The main ingredient in ointments is oil. The main ingredient in creams is water. 5) Specially formulated ointments and ...
How are drugs developed?
... in addition to the inconvenience of having to take various different drugs, this system of administration causes a high number of side effects. The objective of this research group is to combine two drugs by means of a molecule chain, forming one single, more complex molecule which would make it pos ...
... in addition to the inconvenience of having to take various different drugs, this system of administration causes a high number of side effects. The objective of this research group is to combine two drugs by means of a molecule chain, forming one single, more complex molecule which would make it pos ...
INTRODUCTION TO MEDICINAL CHEMISTRY
... Pure organic compounds are the chief source of agents for the cure, mitigation or the prevention of disease. These remedial agents could be classified according to their origin: • Natural compounds: materials obtained from both plant and animal, e.g. vitamins, hormones, amino acids, antibiotics, alk ...
... Pure organic compounds are the chief source of agents for the cure, mitigation or the prevention of disease. These remedial agents could be classified according to their origin: • Natural compounds: materials obtained from both plant and animal, e.g. vitamins, hormones, amino acids, antibiotics, alk ...
Syllabus
... Dass, New Age International (P) Ltd. , Publishers, Ansari road, Second edition, New Delhi-110002. 3. I. L. Finar, Organic Chemistry, Vol. I and II, The English Language Book Society. 4. P.Sykes, A Guidebook to Machanisms in Organic Chemistry, Orient Longman, New Delhi. 5. J. March, Advanced Organic ...
... Dass, New Age International (P) Ltd. , Publishers, Ansari road, Second edition, New Delhi-110002. 3. I. L. Finar, Organic Chemistry, Vol. I and II, The English Language Book Society. 4. P.Sykes, A Guidebook to Machanisms in Organic Chemistry, Orient Longman, New Delhi. 5. J. March, Advanced Organic ...
Know the facts about drugs
... common are the leaves and stalks of the plant, called grass or weed. The third kind, cannabis oil, is rarely seen in Ireland. Cannabis is usually rolled with tobacco into a ‘joint’ or ‘spliff’ and smoked, but it can also be cooked and eaten. Effects – Getting ‘stoned’ on cannabis makes you feel rela ...
... common are the leaves and stalks of the plant, called grass or weed. The third kind, cannabis oil, is rarely seen in Ireland. Cannabis is usually rolled with tobacco into a ‘joint’ or ‘spliff’ and smoked, but it can also be cooked and eaten. Effects – Getting ‘stoned’ on cannabis makes you feel rela ...
Luitpold Animal Health - Luitpold Pharmaceuticals
... appropriate treatment regimen for your animals. Luitpold has established a dedicated webpage on www.adequan.com where concerned parties can register to receive future communications and updates on this matter. You may also contact our Customer Service Department at 1-800458-0163. Adequan® i.m. and I ...
... appropriate treatment regimen for your animals. Luitpold has established a dedicated webpage on www.adequan.com where concerned parties can register to receive future communications and updates on this matter. You may also contact our Customer Service Department at 1-800458-0163. Adequan® i.m. and I ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.