It is recommended that the MAH shall submit the PSUR
... The Central Drugs Standard Control Organization (CDSCO), being the apex regulatory authority for approval of drugs in India, is committed to safeguard and enhance the Public Health by assuring the safety, efficacy and quality of drugs, cosmetics and medical devices. India has extensive Pharmacovigil ...
... The Central Drugs Standard Control Organization (CDSCO), being the apex regulatory authority for approval of drugs in India, is committed to safeguard and enhance the Public Health by assuring the safety, efficacy and quality of drugs, cosmetics and medical devices. India has extensive Pharmacovigil ...
Psychopharmacology Training
... Others might work on the enzyme MAO Some have direct actions on only one monoamine NT system, while others work on multiple monoamine NT systems The immediate pharmacological actions of all ADs eventually have the effect of boosting the levels of monoamine NTs ...
... Others might work on the enzyme MAO Some have direct actions on only one monoamine NT system, while others work on multiple monoamine NT systems The immediate pharmacological actions of all ADs eventually have the effect of boosting the levels of monoamine NTs ...
Introduction to Drug Utilization Research
... adults. The first study used antidiabetic drugs as an example: it was found that the sum of the DDDs of insulin and oral antidiabetic drugs (about 20 DDDs per1000 inhabitants per day) roughly corresponded to the morbidity due to diabetes after correction for the number of patients treated with dieta ...
... adults. The first study used antidiabetic drugs as an example: it was found that the sum of the DDDs of insulin and oral antidiabetic drugs (about 20 DDDs per1000 inhabitants per day) roughly corresponded to the morbidity due to diabetes after correction for the number of patients treated with dieta ...
05-dhamesha prakash
... Humankind‘s efforts to confront disease dates back to early civilization. Substances taken from nature were tested and used to treat dysfunctions of physiological life processes, ...
... Humankind‘s efforts to confront disease dates back to early civilization. Substances taken from nature were tested and used to treat dysfunctions of physiological life processes, ...
A Multimodal Data Analysis Approach for Targeted Drug Discovery
... (b) choosing a binding site for docking. Owing to the advances in experimental methods such as nuclear magnetic resonance (NMR) spectroscopy, X-ray crystallography, and electron microscopy (EM), we now know the 3D structures of thousands of protein targets [17]. The vast majority of these structures ...
... (b) choosing a binding site for docking. Owing to the advances in experimental methods such as nuclear magnetic resonance (NMR) spectroscopy, X-ray crystallography, and electron microscopy (EM), we now know the 3D structures of thousands of protein targets [17]. The vast majority of these structures ...
HERE - URMC
... primarily prescription pain relievers and heroin, are the main drugs associated with overdose deaths. In 2014, opioids were involved in 28,647 deaths, or 61% of all drug overdose deaths; the rate of opioid overdoses ...
... primarily prescription pain relievers and heroin, are the main drugs associated with overdose deaths. In 2014, opioids were involved in 28,647 deaths, or 61% of all drug overdose deaths; the rate of opioid overdoses ...
PDF - Journal of Nanobiotechnology
... amounts from lipid-based drug delivery systems, such as NLCs and SMEDDS, the cumulative release of FNB increased with introduction of lipase. Pancreatic lipase, bile salts and phospholipids are continuously secreted into the GIT. Lipid-based drug delivery systems are digested by pancreatic lipase to ...
... amounts from lipid-based drug delivery systems, such as NLCs and SMEDDS, the cumulative release of FNB increased with introduction of lipase. Pancreatic lipase, bile salts and phospholipids are continuously secreted into the GIT. Lipid-based drug delivery systems are digested by pancreatic lipase to ...
New Drugs and Formulations: Effect on Therapeutic Paradigms
... Phase 2b Khanlou IDSA 2011 #LB9 Rx-experienced; 3-class resistance; (N=113) ...
... Phase 2b Khanlou IDSA 2011 #LB9 Rx-experienced; 3-class resistance; (N=113) ...
Hallucinogens
... readily absorbed from GI tract concentrated in liver, spleen, kidney clinical symptoms similar to LSD nausea and vomiting 30 min to 2h after ingestion ...
... readily absorbed from GI tract concentrated in liver, spleen, kidney clinical symptoms similar to LSD nausea and vomiting 30 min to 2h after ingestion ...
CDAS|Safety Pharmacology
... Database (SED). Our SED contains profile data for more than 2,300 compounds including marketed, failed, withdrawn, and OTC drugs as well as reference agents, agrochemicals and natural product compounds which have been screened through 65 ligand binding and enzyme assays. The result is a highly enric ...
... Database (SED). Our SED contains profile data for more than 2,300 compounds including marketed, failed, withdrawn, and OTC drugs as well as reference agents, agrochemicals and natural product compounds which have been screened through 65 ligand binding and enzyme assays. The result is a highly enric ...
Getting Noticed: The Importance of
... Case Study – Purple Pill • Purple Pill - a prescription drug Prilosec manufactured by AstraZeneca for relief from heartburn caused by acid reflux disease. • An huge marketing campaign was carried out in 1997, where advertisements for the “Purple Pill” appeared everywhere—on TV, the Internet, and in ...
... Case Study – Purple Pill • Purple Pill - a prescription drug Prilosec manufactured by AstraZeneca for relief from heartburn caused by acid reflux disease. • An huge marketing campaign was carried out in 1997, where advertisements for the “Purple Pill” appeared everywhere—on TV, the Internet, and in ...
VALIDATED EXTRACTIVE SPECTROPHOTOMETRIC ESTIMATION OF CINITAPRIDE IN PURE AND ITS SOLID DOSAGE FORM Research Article
... chemical reactions upon which the procedures are based rather than upon the sophistication of the instrument. This aspect of spectrophotometric analysis is of major interest in analytical pharmacy since it offers distinct possibility in the assay of a particular componen ...
... chemical reactions upon which the procedures are based rather than upon the sophistication of the instrument. This aspect of spectrophotometric analysis is of major interest in analytical pharmacy since it offers distinct possibility in the assay of a particular componen ...
national pharmaceutical drug misuse
... individuals who unintentionally misuse these medications and who have developed an iatrogenic dependence2 (Royal Australasian College of Physicians, RACP, 2009). So too for some, the benefits derived from the use of medicines are no longer optimal and alternative more effective treatment options exi ...
... individuals who unintentionally misuse these medications and who have developed an iatrogenic dependence2 (Royal Australasian College of Physicians, RACP, 2009). So too for some, the benefits derived from the use of medicines are no longer optimal and alternative more effective treatment options exi ...
Anti Ulceration and Anti Emetics
... cationic groups in proteins, glycoproteins, etc. It can form complex gels with mucus, an action that is thought to decrease the degradation of mucus by pepsin and to limit the diffusion of H+. Sucralfate can also inhibit the action of pepsin and stimulate secretion of mucus, bicarbonate and prostagl ...
... cationic groups in proteins, glycoproteins, etc. It can form complex gels with mucus, an action that is thought to decrease the degradation of mucus by pepsin and to limit the diffusion of H+. Sucralfate can also inhibit the action of pepsin and stimulate secretion of mucus, bicarbonate and prostagl ...
APPLICATION OF NOVEL CONCEPT OF MIXED SOLVENCY IN THE DESIGN... DEVELOPMENT OF FLOATING MICROSPHERS OF FUROSEMIDE
... INTRODUCTION Oral drug delivery is the most desirable method of administering therapeutic agents mainly because of patient acceptance, convenience in administration, and cost-effective manufacturing process. For many drug substances, conventional immediate-release formulations provide clinically eff ...
... INTRODUCTION Oral drug delivery is the most desirable method of administering therapeutic agents mainly because of patient acceptance, convenience in administration, and cost-effective manufacturing process. For many drug substances, conventional immediate-release formulations provide clinically eff ...
Hydroquinine hydrobromide and hypoglycaemia
... Netherlands for the treatment of nocturnal cramps when treatment with drugs is considered necessary. It is available in the Netherlands since March 1990 as an over-the-counter drug with a dose of 200 mg with the evening meal and a further 100 mg at bedtime for 14 days. According to the Summary of Pr ...
... Netherlands for the treatment of nocturnal cramps when treatment with drugs is considered necessary. It is available in the Netherlands since March 1990 as an over-the-counter drug with a dose of 200 mg with the evening meal and a further 100 mg at bedtime for 14 days. According to the Summary of Pr ...
points to consider on multiplicity issues in clinical trials
... Here, interpretation of the results is most clear-cut because, in order to provide sufficient evidence of the clinically relevant treatment benefit, each null hypotheses on every primary variable has to be rejected at the same significance level (e.g. 0.05). For examples of this clinical situation, ...
... Here, interpretation of the results is most clear-cut because, in order to provide sufficient evidence of the clinically relevant treatment benefit, each null hypotheses on every primary variable has to be rejected at the same significance level (e.g. 0.05). For examples of this clinical situation, ...
available now
... indication for another class • Specified particular antihypertensive medication classes for patients with compelling indications, ie, diabetes, CKD, heart failure, myocardial infarction, stroke, and high CVD risk • Included a comprehensive table of oral antihypertensive drugs including names and usu ...
... indication for another class • Specified particular antihypertensive medication classes for patients with compelling indications, ie, diabetes, CKD, heart failure, myocardial infarction, stroke, and high CVD risk • Included a comprehensive table of oral antihypertensive drugs including names and usu ...
bicycle therapeutics announces a candidate preclinical milestone in
... inhibitor, holds great promise for ophthalmology applications, expanding the range of treatment options available for people with diseases of the eye, particularly DME. We are rapidly moving towards the clinic, and expect to begin clinical development early in 2018.” About Bicycle Therapeutics Bicyc ...
... inhibitor, holds great promise for ophthalmology applications, expanding the range of treatment options available for people with diseases of the eye, particularly DME. We are rapidly moving towards the clinic, and expect to begin clinical development early in 2018.” About Bicycle Therapeutics Bicyc ...
Beta 2 Agonist: Therapeutic Use Exemption, Misuse in Sports and its
... 3.5 Other Adverse Effects In rare cases, a serious allergic reaction may occur while using beta-2 agonist medications. Symptoms include hives, difficulty breathing and swelling of your face, lips, tongue or throat, reports. Other serious effects include depression; fainting, rapid heartbeat and jaun ...
... 3.5 Other Adverse Effects In rare cases, a serious allergic reaction may occur while using beta-2 agonist medications. Symptoms include hives, difficulty breathing and swelling of your face, lips, tongue or throat, reports. Other serious effects include depression; fainting, rapid heartbeat and jaun ...
Anticholinergic drugs
... CNS. Atropine has an overall stimulant action. Its stimulant effects are not appreciable at low doses which produce peripheral effects because of restricted entry into the brain. Hyoscine produces central depressant effects even at low doses. •Atropine stimulates many medullar centers – vagal, respi ...
... CNS. Atropine has an overall stimulant action. Its stimulant effects are not appreciable at low doses which produce peripheral effects because of restricted entry into the brain. Hyoscine produces central depressant effects even at low doses. •Atropine stimulates many medullar centers – vagal, respi ...
Slide 1
... CNS. Atropine has an overall stimulant action. Its stimulant effects are not appreciable at low doses which produce peripheral effects because of restricted entry into the brain. Hyoscine produces central depressant effects even at low doses. •Atropine stimulates many medullar centers – vagal, respi ...
... CNS. Atropine has an overall stimulant action. Its stimulant effects are not appreciable at low doses which produce peripheral effects because of restricted entry into the brain. Hyoscine produces central depressant effects even at low doses. •Atropine stimulates many medullar centers – vagal, respi ...
pharmacology 2008 - addiction education home
... Effects range from the artificial sociability imbued by various intoxicating agents to the depressed and socially withdrawn state frequently observed in chronic drug users. Understanding such effects is of great potential significance in addiction neurobiology. In this review we focus on the 'social ...
... Effects range from the artificial sociability imbued by various intoxicating agents to the depressed and socially withdrawn state frequently observed in chronic drug users. Understanding such effects is of great potential significance in addiction neurobiology. In this review we focus on the 'social ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.