PREPARATION AND EVALUATION OF NOVEL TOPICAL GEL PREPARATIONS FOR WOUND
... Diabetes mellitus is one of the metabolic disorders that impedes normal steps of wound healing process. Recently, statins have been shown to have anticoagulant, immunosuppressive and antiproliferative effects that could conceivably affect wound healing or the risk of wound complications after surger ...
... Diabetes mellitus is one of the metabolic disorders that impedes normal steps of wound healing process. Recently, statins have been shown to have anticoagulant, immunosuppressive and antiproliferative effects that could conceivably affect wound healing or the risk of wound complications after surger ...
Brain death
... The irreversible cessation of brainstem function (brainstem death), whether induced by intracranial events or result of extra-cranial phenomena will produce the same clinical state Brainstem death is equivalent to death of the individual. U.K. Criteria for the diagnosis of brainstem death (Working G ...
... The irreversible cessation of brainstem function (brainstem death), whether induced by intracranial events or result of extra-cranial phenomena will produce the same clinical state Brainstem death is equivalent to death of the individual. U.K. Criteria for the diagnosis of brainstem death (Working G ...
Pharmacokinetics Study of Pioglitazone (30 mg) Tablets in Healthy
... Accomplishment of clinical benefits, safe and effective drug therapy is difficult due to large interpatient variability in response to many drugs.3 The knowledge of a drug’s pharmacokinetic profile within individual has allowed the clinician to ensure optimization of the drug’s performance.7 Hence, ...
... Accomplishment of clinical benefits, safe and effective drug therapy is difficult due to large interpatient variability in response to many drugs.3 The knowledge of a drug’s pharmacokinetic profile within individual has allowed the clinician to ensure optimization of the drug’s performance.7 Hence, ...
ASHP Guidelines on Surgery and Anesthesi
... compliance with established guidelines. In organizations with automated anesthesia record keepers, collection and manipulation of medication-use information is greatly facilitated.11 Drug Information. The pharmacist should provide timely and accurate drug information in response to known needs and r ...
... compliance with established guidelines. In organizations with automated anesthesia record keepers, collection and manipulation of medication-use information is greatly facilitated.11 Drug Information. The pharmacist should provide timely and accurate drug information in response to known needs and r ...
The Top 6 June specials 2015
... The most common side effects seen with midodrine are piloerection (goose bumps), pruritus and paraesthesia (particularly of the scalp), urinary retention or urgency, and supine hypertension. The longer-term efficacy and safety of midodrine has not been assessed in the RCTs, nor has its effect on act ...
... The most common side effects seen with midodrine are piloerection (goose bumps), pruritus and paraesthesia (particularly of the scalp), urinary retention or urgency, and supine hypertension. The longer-term efficacy and safety of midodrine has not been assessed in the RCTs, nor has its effect on act ...
GIST clinical trials - The Life Raft Group
... 89%-Obtaining possible benefit “very important” 17%-Helping future cancer patients/treatments Other factors cited as “very important” 66%-Trust in doctor 66%-Being treated by the latest treatment available 61%-Better standard of care and closer follow-up 71% stated that “surviving for as long ...
... 89%-Obtaining possible benefit “very important” 17%-Helping future cancer patients/treatments Other factors cited as “very important” 66%-Trust in doctor 66%-Being treated by the latest treatment available 61%-Better standard of care and closer follow-up 71% stated that “surviving for as long ...
ANTI-ARRHYTHMIC DRUGS
... postoperative hypertension, and sometimes for hypertensive emergencies, particularly when hypertension is associated with tachycardia ...
... postoperative hypertension, and sometimes for hypertensive emergencies, particularly when hypertension is associated with tachycardia ...
Hypertension Update and Treatment Options
... Combination therapy usually required to reach BP goals ...
... Combination therapy usually required to reach BP goals ...
Complementary Medicine in Allergy and Immunology
... 1. Use of CAM, especially natural products for chronic diseases, is nothing new. In the 1940s and 1950s, pharmacists sold a product known as “Asthmador,” which contained belladonna, an anticholinergic-containing herb. Ma huang was commonly used in herbal preparations marketed for use in asthma, unti ...
... 1. Use of CAM, especially natural products for chronic diseases, is nothing new. In the 1940s and 1950s, pharmacists sold a product known as “Asthmador,” which contained belladonna, an anticholinergic-containing herb. Ma huang was commonly used in herbal preparations marketed for use in asthma, unti ...
Iboga and Ibogaine - From Forest to Lab
... National Institute on Drug Abuse (NIDA) for ibogaine. •Acute Oral Toxicity Study of Ibogaine HCl in Rats. •32 Day Range-Finding Study of Ibogaine in Rats. •Dose Response Neurotoxicity Study of Ibogaine in Rats. •Dose Response Effect of Ibogaine on Analgesia and Mortality in Morphine-Dependent Rats. ...
... National Institute on Drug Abuse (NIDA) for ibogaine. •Acute Oral Toxicity Study of Ibogaine HCl in Rats. •32 Day Range-Finding Study of Ibogaine in Rats. •Dose Response Neurotoxicity Study of Ibogaine in Rats. •Dose Response Effect of Ibogaine on Analgesia and Mortality in Morphine-Dependent Rats. ...
Formulation and Evaluation of Almotriptan Malate Nasal Drops
... E15 was added in different proportions from 2.57.5% w/v. The osmolarity was recorded on Osmomat 30. Viscosity of the solutions was recorded using a cone and plate viscometer. In vitro permeation studies were performed using a Franz diffusion cell with dialysis membrane. The receptor compartment cont ...
... E15 was added in different proportions from 2.57.5% w/v. The osmolarity was recorded on Osmomat 30. Viscosity of the solutions was recorded using a cone and plate viscometer. In vitro permeation studies were performed using a Franz diffusion cell with dialysis membrane. The receptor compartment cont ...
Research Review Chemicals March16
... Median lethal dose (LD50) is the amount of a substance required to kill 50% of a test population. Assuming a body weight of 75kg, the LD50 for water is six litres when imbibed all at once11, that of caffeine is 118 cups of coffee (or 175 shots of espresso)7 and that of ethanol is 585mL (or 29 shots ...
... Median lethal dose (LD50) is the amount of a substance required to kill 50% of a test population. Assuming a body weight of 75kg, the LD50 for water is six litres when imbibed all at once11, that of caffeine is 118 cups of coffee (or 175 shots of espresso)7 and that of ethanol is 585mL (or 29 shots ...
Development and application of highly sensitive high−performance
... In recent years, many kinds of drugs of abuse have been used worldwide and caused serious social problems. Among these, methamphetamine (MP) is the most popular drug of abuse in Japan. In addition to MP illegal designer drugs, 3,4−methylenedioxymethamphetamine and 3,4−methylendioxyamphetamine have b ...
... In recent years, many kinds of drugs of abuse have been used worldwide and caused serious social problems. Among these, methamphetamine (MP) is the most popular drug of abuse in Japan. In addition to MP illegal designer drugs, 3,4−methylenedioxymethamphetamine and 3,4−methylendioxyamphetamine have b ...
Pharmacokinetics of Pyrazoloacridine in the Rhesus Monkey
... lectively inhibits RNA synthesis (1). Interest in pyrazoloacridine as a potential anticancer drug is based on several important characteristics of this agent, including solid tumor selectivity (1-3), activity against hypoxic and noncycling cells (1, 4), and activity against cells having the multidru ...
... lectively inhibits RNA synthesis (1). Interest in pyrazoloacridine as a potential anticancer drug is based on several important characteristics of this agent, including solid tumor selectivity (1-3), activity against hypoxic and noncycling cells (1, 4), and activity against cells having the multidru ...
Guideline on the Evaluation of the Pharmacokinetics of
... important organ with respect to drug disposition, patients with hepatic impairment constitute an important subgroup of such special populations. Hepatic function decreases with age, but due to the high capacity of the liver this is considered not to change the pharmacokinetics to a clinically releva ...
... important organ with respect to drug disposition, patients with hepatic impairment constitute an important subgroup of such special populations. Hepatic function decreases with age, but due to the high capacity of the liver this is considered not to change the pharmacokinetics to a clinically releva ...
Bledsoe_V1_ch09a
... This typically includes the common concentration of the available preparations; many drugs come in different concentrations. ...
... This typically includes the common concentration of the available preparations; many drugs come in different concentrations. ...
King Saud University 351 PHL
... Effect of certain agonists & their antagonists on the isolated rabbit intestine Points to be discussed: 1. Agonists & their specific antagonists acting on isolated rabbit intestine. 2. Determine the site of action of unknown drug. Lab work: 1- Material: Physiological solution: Tyrode’s solution. ...
... Effect of certain agonists & their antagonists on the isolated rabbit intestine Points to be discussed: 1. Agonists & their specific antagonists acting on isolated rabbit intestine. 2. Determine the site of action of unknown drug. Lab work: 1- Material: Physiological solution: Tyrode’s solution. ...
Guidelines for the medical management of patients with
... that there were 72 700 dependent methamphetamine users, or 7.3 per 1000 population aged 15–49 years.35 It is important to be aware that amphetamine use is likely to be a part of a polydrug use pattern. For example, in the National Drug Strategy Household Survey,34 recent users of amphetamines (used ...
... that there were 72 700 dependent methamphetamine users, or 7.3 per 1000 population aged 15–49 years.35 It is important to be aware that amphetamine use is likely to be a part of a polydrug use pattern. For example, in the National Drug Strategy Household Survey,34 recent users of amphetamines (used ...
TYPE OF MANUSCRIPT: ORIGINAL RESEARCH ARTICLE
... Wound healing is an intricate and continual cascade of events, with various cellular and biochemical processes, ultimately resulting in the reconstruction and regeneration of damaged tissue. Plants and their extracts have immense potential for the management and treatment of wounds. The phyto-medici ...
... Wound healing is an intricate and continual cascade of events, with various cellular and biochemical processes, ultimately resulting in the reconstruction and regeneration of damaged tissue. Plants and their extracts have immense potential for the management and treatment of wounds. The phyto-medici ...
Determination and validation of hydrazine content by
... A simple and sensitive spectrophotometric method was developed, optimized and validated for the determination of hydrazine in various drug substances. Which is the process genotoxic impurity. The validation of analytical method was realized trough specificity, linearity, Limit of detection, Limit of ...
... A simple and sensitive spectrophotometric method was developed, optimized and validated for the determination of hydrazine in various drug substances. Which is the process genotoxic impurity. The validation of analytical method was realized trough specificity, linearity, Limit of detection, Limit of ...
Renal Dose Adjustment per Pharmacy
... appropriateness of dosing by a pharmacist at least every 72 hours. B. The need for a SCr should be evaluated at least every 3-7 days for appropriate monitoring of patients on these medications. If this is not ordered by a physician, the pharmacist is allowed to order a SCr to estimate CrCl if applic ...
... appropriateness of dosing by a pharmacist at least every 72 hours. B. The need for a SCr should be evaluated at least every 3-7 days for appropriate monitoring of patients on these medications. If this is not ordered by a physician, the pharmacist is allowed to order a SCr to estimate CrCl if applic ...
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF ONDANSETRON HYDROCHLORIDE Research Article
... which has been proved effective in prevention of chemotherapy and radiotherapy-induced nausea and vomiting. Ondansetron hydrochloride has been used by oral and injectable administration. Ondansetron hydrochloride is rapidly absorbed orally, but extensively metabolized by the liver. It should be admi ...
... which has been proved effective in prevention of chemotherapy and radiotherapy-induced nausea and vomiting. Ondansetron hydrochloride has been used by oral and injectable administration. Ondansetron hydrochloride is rapidly absorbed orally, but extensively metabolized by the liver. It should be admi ...
taste masking methods and agents in pharmaceutical formulations
... odour of their own to product and have a mild anesthetic effect on sensory receptor organs associated with taste8. Sweeteners Use of sweeteners is the simplest and common approach for taste masking especially in the chewable tablets, pediatric and liquid formulations. But it is not very successful f ...
... odour of their own to product and have a mild anesthetic effect on sensory receptor organs associated with taste8. Sweeteners Use of sweeteners is the simplest and common approach for taste masking especially in the chewable tablets, pediatric and liquid formulations. But it is not very successful f ...
Natural products as starting points for future anti
... Results: Natural product scaffolds have been the basis of the majority of current anti-malarial medicines. Molecules such as quinine, lapachol and artemisinin were originally isolated from herbal medicinal products. After improvement with medicinal chemistry and formulation technologies, and combina ...
... Results: Natural product scaffolds have been the basis of the majority of current anti-malarial medicines. Molecules such as quinine, lapachol and artemisinin were originally isolated from herbal medicinal products. After improvement with medicinal chemistry and formulation technologies, and combina ...
INVESTIGATION OF ANALGESIC AND ANTI-INFLAMMATORY POTENTIAL OF ETHANOLIC WIGHTIANA Research Article
... The abdominal writhing response induced by acetic acid is sensitive process to establish peripherally acting analgesics. Local peritoneal receptors are responsible for abdominal writhing action. Intraperitoneal administration of acetic acid causes an increase in of PGE 2 and PGF 2 α and produce anal ...
... The abdominal writhing response induced by acetic acid is sensitive process to establish peripherally acting analgesics. Local peritoneal receptors are responsible for abdominal writhing action. Intraperitoneal administration of acetic acid causes an increase in of PGE 2 and PGF 2 α and produce anal ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.